Information on EC 1.1.2.3 - L-lactate dehydrogenase (cytochrome)

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

EC NUMBER
COMMENTARY
1.1.2.3
-
RECOMMENDED NAME
GeneOntology No.
L-lactate dehydrogenase (cytochrome)
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Metabolic pathways
-
methylglyoxal degradation V
-
Pyruvate metabolism
-
SYSTEMATIC NAME
IUBMB Comments
(S)-lactate:ferricytochrome-c 2-oxidoreductase
Identical with cytochrome b2; a flavohemoprotein (FMN).
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
Cyb2
Saccharomyces cerevisiae D273-10B/A1
-
-
-
cytochrome b2
-
-
-
-
cytochrome c oxido reductase
-
-
FC b2
Ogataea angusta 356, Ogataea angusta C-105, Ogataea angusta K-105
-
-
-
FC b2
Saccharomyces cerevisiae IZR-106, Saccharomyces cerevisiae IZR-42
-
-
-
flavocytochrome b
-
-
flavocytochrome b2
-
-
-
-
flavocytochrome b2
-
-
flavocytochrome b2
Ogataea angusta 356, Ogataea angusta C-105, Ogataea angusta K-105
-
-
-
flavocytochrome b2
P00175
-
flavocytochrome b2
Saccharomyces cerevisiae D273-10B/A1, Saccharomyces cerevisiae IZR-106, Saccharomyces cerevisiae IZR-42
-
-
-
flavocytochrome b2
-
-
L(+)-lactate:cytochrome c oxidoreductase
-
-
-
-
L-(+)-lactate ferricytochrome c oxidoreductase
-
-
L-lactate cytochrome c oxidoreductase
-
-
-
-
L-lactate cytochrome c oxidoreductase
-
-
L-lactate cytochrome c oxidoreductase
Ogataea angusta 356, Ogataea angusta K-105
-
-
-
L-lactate cytochrome c oxidoreductase
-
-
L-lactate cytochrome c oxidoreductase
P00175
-
L-lactate cytochrome c oxidoreductase
Saccharomyces cerevisiae IZR-106, Saccharomyces cerevisiae IZR-42
-
-
-
L-lactate cytochrome c reductase
-
-
-
-
L-lactate dehydrogenase [Cytochrome]
-
-
-
-
L-lactate ferricytochrome C oxidoreductase
-
-
-
-
L-lactate ferricytochrome C oxidoreductase
-
-
L-lactate: cytochrome c oxidoreductase
-
-
L-lactate:cytochrome c oxidoreductase
-
-
L-lactate:cytochrome c oxidoreductase
P00175
-
L-lactate:cytochrome c-oxidoreductase
-
-
L-lactate:cytochrome c-oxidoreductase
Ogataea angusta C-105
-
-
-
L-lactate:cytochrome c-oxidoreductase
-
-
L-LCR
-
-
-
-
L-LDH (FMN-dependent)
-
-
lactate dehydrogenase (cytochrome)
-
-
-
-
lactic acid dehydrogenase
-
-
-
-
lactic cytochrome c reductase
-
-
-
-
NAD+ - independent LDH
-
-
CAS REGISTRY NUMBER
COMMENTARY
9078-32-4
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
L. Corm, before, 10 and 30 days after rooting, three isoforms
-
-
Manually annotated by BRENDA team
three isoforms
-
-
Manually annotated by BRENDA team
356; K-105
-
-
Manually annotated by BRENDA team
i.e. Pichia angusa, gene CYB2
-
-
Manually annotated by BRENDA team
Ogataea angusta 356
356
-
-
Manually annotated by BRENDA team
Ogataea angusta C-105
-
-
-
Manually annotated by BRENDA team
Ogataea angusta K-105
K-105
-
-
Manually annotated by BRENDA team
cytochrome domain expressed in Escherichia coli
-
-
Manually annotated by BRENDA team
IZR-106; IZR-42
-
-
Manually annotated by BRENDA team
Saccharomyces cerevisiae D273-10B/A1
-
-
-
Manually annotated by BRENDA team
Saccharomyces cerevisiae IZR-106
IZR-106
-
-
Manually annotated by BRENDA team
Saccharomyces cerevisiae IZR-42
IZR-42
-
-
Manually annotated by BRENDA team
flavin and heme domain expressed in Escherichia coli
-
-
Manually annotated by BRENDA team
pH RANGE
pH RANGE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
5.2
-
-
almost no activity
pI VALUE
pI VALUE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
SOURCE TISSUE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
SOURCE
-
optimization of culture conditions for recombinant cells of strain C-105 expressing gene CYB2 and showing increased FCb2 activity
Manually annotated by BRENDA team
-
two isozymes
Manually annotated by BRENDA team
PDB
SCOP
CATH
ORGANISM
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
TEMPERATURE STABILITY
TEMPERATURE STABILITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
additional information
-
-
thermostable enzyme
APPLICATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
analysis
-
sensitive and stable visualization of enzyme activity in cell-free extracts or during purification by by formation of precipitates of Berlin blue
analysis
-
development of a amperometric biosensor selective to L-lactate, bioanalytical properties are very fast response and high sensitivity and selectivity
environmental protection
-
the reductive pathway of the enzyme resulting in formation of less toxic Cr(III)-species is suggested to be the most important among possible mechanisms for chromate biodetoxification
synthesis
-
the enzyme is potentially important for bioanalytical technologies for highly selective assays of L-lactate in biological fluids and foods
environmental protection
Ogataea angusta C-105
-
the reductive pathway of the enzyme resulting in formation of less toxic Cr(III)-species is suggested to be the most important among possible mechanisms for chromate biodetoxification
-