Information on EC 3.1.1.1 - carboxylesterase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Xeropicta derbentina

EC NUMBER
COMMENTARY
3.1.1.1
-
RECOMMENDED NAME
GeneOntology No.
carboxylesterase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
rapid-equilibrium random mechanism
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
-
-
-
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
catalytic triad near the C-terminus includes His275
Q9LAB8
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
active site residues are Ser203, His448, and Asp97
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
reaction and substrate binding mechanism, structure distinct binding pockets of the wild-type and mutant enzymes, Gly105 plays an important role
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
a catalytic triad is formed by residues Ser221, Glu353, and His466; a catalytic triad is formed by residues Ser224, Glu341, and His452; a catalytic triad is formed by residues Ser227, Glu344, and His456; a catalytic triad is formed by residues Ser230, Glu347, and His459
O35535, O70631, P16303, Q63108, Q64573, Q8K3R0
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
reaction mechanism
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
active site structure, catalytic triad consists of residues Ser82, His235, and Asp207
-, P13001
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
active site structure, substrate binding and reaction mechanism
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
reaction mechanism
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
the catalytic triad consists of Ser160, His285, ans ASp255, and an oxyanion hole binding the nucleophile is formed by Gly88, Gly89, and Ala161
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
catalytic triad consists of S325, D516, and H558
Q840T2
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
catalytic triad consists of S162, H290, and D260 and is located at the bottom of a solvent accessible pocket. The guanidine moiety close to H290 confers a low pH shift of the catalytic His molecule
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
catalytic triad consists of S325, D516, and H558
Lactobacillus casei CL96
-
-
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
active site residues are Ser203, His448, and Asp97
Sus scrofa PLE
-
-
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hydrolysis
-
-
hydrolysis of carboxylic ester
-
-
-
-
hydrolysis of carboxylic or thio-esters
-, P13001
-
hydrolysis of carboxylic or thio-esters
Escherichia coli DH5alpha
-
-
-
hydrolysis of esters
P04335
-
PATHWAY
KEGG Link
MetaCyc Link
Drug metabolism - other enzymes
-
methyl indole-3-acetate interconversion
-
retinol biosynthesis
-
SYSTEMATIC NAME
IUBMB Comments
carboxylic-ester hydrolase
Wide specificity. The enzymes from microsomes also catalyse the reactions of EC 3.1.1.2 (arylesterase), EC 3.1.1.5 (lysophospholipase), EC 3.1.1.6 (acetylesterase), EC 3.1.1.23 (acylglycerol lipase), EC 3.1.1.28 (acylcarnitine hydrolase), EC 3.1.2.2 (palmitoyl-CoA hydrolase), EC 3.5.1.4 (amidase) and EC 3.5.1.13 (aryl-acylamidase). Also hydrolyses vitamin A esters.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
4-nitrophenyl esterase
-
-
ACAT
-
-
-
-
Acetyl esterase
-
-
acid retinyl ester hydrolase
-
-
Acyl coenzyme A:cholesterol acyltransferase
-
-
-
-
acylcarnitine hydrolase
-
-
AF1763
O28511
gene name
AF1763
O28511
locus name
ali-esterase
-
-
-
-
aliesterase
-
-
-
-
alpha-carboxylesterase
-
-
-
-
aspirin hydrolase
-
-
B-esterase
-
-
-
-
BioHs
B0M0H6
-
BioHs
B0M0H6
-
-
Brain carboxylesterase hBr1
-
-
-
-
BsE-NP01
D0EPY0
-
BsE-NP01
Bacillus subtilis ECU0554
D0EPY0
-
-
butyrate esterase
-
-
-
-
butyryl esterase
-
-
-
-
CaE
-
-
-
-
carboxyesterase
-
-
-
-
Carboxyesterase ES-10
-
-
-
-
carboxyl ester hydrolase
-
-
-
-
carboxyl esterase
-
-
carboxyl esterase
Aspergillus nomius HS-1
-
-
-
carboxyl/cholinesterase
-
-
carboxylate esterase
-
-
-
-
carboxylesterase 1
P23141
-
carboxylesterase 1
-
-
carboxylesterase 1A2
-
-
carboxylesterase 2
-
-
carboxylesterase B
-
-
carboxylesterase B
Escherichia coli HB17
-
-
-
carboxylesterase B1
Culex sp.
-
-
carboxylesterase-2
-
-
Carboxylesterase-5C
-
-
-
-
carboxylic acid esterase
-
-
-
-
carboxylic ester hydrolase
-
-
-
-
carboxylic esterase
-
-
-
-
Carboxylic-ester hydrolase
-
-
-
-
Carboxylic-ester hydrolase
Anoxybacillus sp.
-
-
Carboxylic-ester hydrolase
-
-
-
CarE
O76177
-
CarE
O76177 and Q95UJ4
-
CE1
-
carboxylesterase from liver
CE1
-
hepatic carboxylesterase
CE1
-
isozyme
CE2
-
isozyme
CE21p
O35535
-
CES
-
-
-
-
CES-2
-
-
CES1
-
hepatic carboxylesterase
CES1
-
isoform
CES1
-
isozyme
CES1
P23141
-
CES1
P23141
isozyme
CES1
-
isozyme
CES1-b
-
carboxylesterase 1 form b
CES1-c
-
carboxylesterase 1 form c
CES1A
P23141
isoform
CES1A
P23141
isozyme
CES1A1
P23141
precursor of CES1A
CES1A2
-
-
CES1A2
P23141
precursor of CES1A
CES2
-
isoform
CES2
-
isozyme
CES2
P23141
isozyme
CES2
-
isozyme
CES2
O70631
-
CES2
O70631
isozyme
cholesteryl ester hydrolase
-
-
cocaine esterase
-
-
-
-
cocaine:benzoylecgonine esterase
-
-
COE
B3SST1 and B3SST2
-
CPT-CE
-
-
Egasyn
-
-
-
-
Es-22
-
-
-
-
ES-HTEL
-
-
-
-
ES-HVEL
-
-
-
-
ES-Male
-
-
-
-
ES-THET
-
-
-
-
ES10
-
isozyme
ES10
O70631
isozyme
ES10
P16303
-
ES11
-
isozyme
ES3
Q63108
-
ES4
O70631
isozyme
ES4
Q64573
-
EST
Anoxybacillus sp.
-
-
EST-5A
-
-
-
-
EST-5B
-
-
-
-
EST-5C
-
-
-
-
Est0071
Q976W8
-
Est0071
Sulfolobus tokodaii 7
Q976W8
-
-
Est1
O73957
gene name
Est1
O73957
gene name
-
Est1
Sulfolobus solfataricus P1
-
-
-
EST2
Q97VU2
-
-
ESt3
Q97VW1
-
-
Est3 esterase
Q97VW1
-
Est3 esterase
Q97VW1
-
-
EstA
Acinetobacter lwoffii I6C-1
-
-
-
EstA
Lactobacillus delbrueckii subsp. lactis MG1363 EstA
-
-
-
EstA esterase
Q8KWI9
-
estBB1
Q4PNS3
-
EstC
Q8KT44
-
EstC
Lactobacillus casei LILA EstC
Q8KT44
-
-
EstC1
Bacillus coagulans 81-11
-
-
-
esterase
P04335
-
esterase 1F
-
-
esterase 2
Q97VU2
-
esterase 2
Q97VU2
-
-
esterase 2B
-
-
esterase 6A
-
-
esterase 9A
-
-
esterase A
-
-
-
-
esterase B
-
-
-
-
esterase D
-
-
-
-
esterase Sso2518
Q97VU1
-
esterase Sso2518
Q97VU1
-
-
esterase, carboxyl
-
-
-
-
Esterase-22
-
-
-
-
Esterase-31
-
-
-
-
EstGtA2
Geobacillus thermodenitrificans CMB-A2
G3JWZ2
-
-
EstP
Q52NW7
-
EstP
Q52NW7
-
-
EstSt7
Q96Z02
-
EstSt7
Sulfolobus tokodaii 7
Q96Z02
-
-
HCE1
-
isozyme
HCE1
P23141
-
HCE2
-
isozyme
hiCE
-
-
hiCE
-
intestinal carboxylaesterase
HMSE
-
-
-
-
hormone-sensitive lipase
-
-
ICE
-
carboxylesterase from intestine
JHE-related
-
gene name
JHER
-
gene name
Kidney microsomal carboxylesterase
-
-
-
-
LIP4
Thalassobacillus sp.
-
-
Liver microsomal carboxylesterase
-
-
-
-
malathion carboxylesterase
-
-
MAP esterase
-
-
MAP esterase
-
-
-
MeIAA esterase
Q9SG92
-
MeSA esterase
-
-
methylbutyrase
-
-
-
-
methylbutyrate esterase
-
-
-
-
Microsomal palmitoyl-CoA hydrolase
-
-
-
-
monobutyrase
-
-
-
-
Non-specific carboxylesterase
-
-
-
-
nonspecific carboxylesterase
-
-
-
-
PA3859
Q9HXE7
-
PI 5.5 esterase
-
-
-
-
PI 6.1 esterase
-
-
-
-
pig liver esterase
-
-
pig liver esterase
Sus scrofa PLE
-
-
-
PLE
Sus scrofa PLE
-
-
-
PPMTase
-
-
PrbA
Enterobacter cloacae EM
-
-
-
prenylated methylated protein methyl esterase
-
-
procaine esterase
-
-
-
-
Proline-beta-naphthylamidase
-
-
-
-
propionyl esterase
-
-
-
-
SABP2's methyl salicylate esterase
-
-
salicylic acid-binding protein 2
-
-
SeE
B5THG6
-
serine-type carboxylesterase
Thalassobacillus sp.
-
-
serine-type carboxylesterase
-
-
-
SiRe0290
F0NDQ1
-
SiRe0290
F0NDQ1
-
-
SshEstI esterase
-
-
SshEstI esterase
Sulfolobus shibatae DSM5389
-
-
-
Sso P1 carboxylesterase
-
-
Sso P1 carboxylesterase
Sulfolobus solfataricus P1
-
-
-
Sso-EST1
Sulfolobus solfataricus P1
-
-
-
SSO2493
Q97VW1
locus name
SSO2493
Q97VW1
locus name; locus name
-
SSO2517
Q97VU2
locus name
SSO2517
Q97VU2
locus name
-
SSoP1 CE
Sulfolobus solfataricus P1
-
-
-
SsoPEst
Q97VU1
-
SsoPEst
Q97VU1
-
-
ST0071
Q976W8
locus name
ST0071
Sulfolobus tokodaii 7
Q976W8
locus name
-
ST2026
Q96Z02
; locus name
ST2026
Sulfolobus tokodaii 7
Q96Z02
; locus name
-
STK_00710
Q976W8
locus name
STK_00710
Sulfolobus tokodaii 7
Q976W8
locus name
-
Sto-Est
Q976W8
-
Sto-Est
Sulfolobus tokodaii 7
Q976W8
-
-
triacetin esterase
-
-
-
-
triacylglycerol hydrolase
-
-
triacylglycerol hydrolase
-
-
triacylglycerol hydrolase
-
-
-
vitamin A esterase
-
-
-
-
Monocyte/macrophage serine esterase
-
-
-
-
additional information
-
the enzyme belongs to the methyl esterase, MES, family
additional information
Q9SG92
the enzyme belongs to the methyl esterase family
additional information
-
the enzyme belongs to the BioH enzyme family
CAS REGISTRY NUMBER
COMMENTARY
9016-18-6
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
strain I6C-1, enzyme EstA
-
-
Manually annotated by BRENDA team
Acinetobacter lwoffii I6C-1
strain I6C-1, enzyme EstA
-
-
Manually annotated by BRENDA team
isoform CXE1
Uniprot
Manually annotated by BRENDA team
Anoxybacillus sp.
-
-
-
Manually annotated by BRENDA team
-
O76177 and Q95UJ4
UniProt
Manually annotated by BRENDA team
strains MRR and MSS
UniProt
Manually annotated by BRENDA team
gene At3g10870 or AtMES17
UniProt
Manually annotated by BRENDA team
isoform AtFSGH
-
-
Manually annotated by BRENDA team
isoform CXE12
-
-
Manually annotated by BRENDA team
isoform CXE18
-
-
Manually annotated by BRENDA team
contains a hyper-thermophilic carboxylaesterase AFEST
-
-
Manually annotated by BRENDA team
strain DSM 4304
-
-
Manually annotated by BRENDA team
strain SC-69828
-
-
Manually annotated by BRENDA team
Arthrobacter globiformis SC-69828
strain SC-69828
-
-
Manually annotated by BRENDA team
family VIII esterase
-
-
Manually annotated by BRENDA team
strain NRRL B-1973
-
-
Manually annotated by BRENDA team
Arthrobacter viscosus NRRL B-1973
strain NRRL B-1973
-
-
Manually annotated by BRENDA team
strain HS-1
-
-
Manually annotated by BRENDA team
Aspergillus nomius HS-1
strain HS-1
-
-
Manually annotated by BRENDA team
moderate thermophile, strain MAS2
-
-
Manually annotated by BRENDA team
strain 81-11
-
-
Manually annotated by BRENDA team
Bacillus coagulans 81-11
strain 81-11
-
-
Manually annotated by BRENDA team
strain BP-7, type B enzyme
-
-
Manually annotated by BRENDA team
strain BP-7, type B enzyme
-
-
Manually annotated by BRENDA team
enantioselective enzyme estBB1
SwissProt
Manually annotated by BRENDA team
isoform BS2, enzyme additionally shows amidase activity
Uniprot
Manually annotated by BRENDA team
recombinant enzyme, 4-nitrophenyl esterase, enzyme contains the GGGX sequence motif
-
-
Manually annotated by BRENDA team
strain 168, isoform CesA, CesB; strain Thai I-8, isoform NP
-
-
Manually annotated by BRENDA team
strain SR22
-
-
Manually annotated by BRENDA team
strasin RRL 1789
-
-
Manually annotated by BRENDA team
Bacillus subtilis 168
strain 168, isoform CesA, CesB
-
-
Manually annotated by BRENDA team
Bacillus subtilis ECU0554
-
UniProt
Manually annotated by BRENDA team
Bacillus subtilis SR22
strain SR22
-
-
Manually annotated by BRENDA team
Bacillus subtilis Thai I-8
strain Thai I-8, isoform NP
-
-
Manually annotated by BRENDA team
fragments; sweetpotato whitefly, strains SUD-S and B-ref
B3SST1 and B3SST2
UniProt
Manually annotated by BRENDA team
gene EstC, formerly Pseudomonas marginata
SwissProt
Manually annotated by BRENDA team
gene lipA encodes a thermostable esterase
-
-
Manually annotated by BRENDA team
Culex sp.
isoform CaE B1
-
-
Manually annotated by BRENDA team
Culex sp.
mosquito
-
-
Manually annotated by BRENDA team
Culex sp.
mosquito, isoform B1, expressed in Escherichia coli
-
-
Manually annotated by BRENDA team
expression in baculoviral system
-
-
Manually annotated by BRENDA team
strain PW1
-
-
Manually annotated by BRENDA team
Emericella nidulans PW1
strain PW1
-
-
Manually annotated by BRENDA team
strain EM, enzyme PrbA
-
-
Manually annotated by BRENDA team
Enterobacter cloacae EM
strain EM, enzyme PrbA
-
-
Manually annotated by BRENDA team
enzyme BioH, selenomethionine enriched protein, contains 2 Gly-Xaa-Ser-Xaa-Gly motifs
-
-
Manually annotated by BRENDA team
gene bioHe
-
-
Manually annotated by BRENDA team
strain HB17
-
-
Manually annotated by BRENDA team
Escherichia coli HB17
strain HB17
-
-
Manually annotated by BRENDA team
isoforms Est30, Est55
-
-
Manually annotated by BRENDA team
Geobacillus stearothermophilus CICC 20156
-
-
-
Manually annotated by BRENDA team
Geobacillus thermodenitrificans CMB-A2
-
G3JWZ2
UniProt
Manually annotated by BRENDA team
at least 4 major isoenzymes in blood monocytes
-
-
Manually annotated by BRENDA team
isoenzyme hBr3/pTARGET and HU1/pTARGET
SwissProt
Manually annotated by BRENDA team
isoform CES2, several splice variants
-
-
Manually annotated by BRENDA team
isoform CES3, expression in baculoviral system; isoforms CES1A1, CES2
-
-
Manually annotated by BRENDA team
isoform hCE1
SwissProt
Manually annotated by BRENDA team
isoform hCE1
-
-
Manually annotated by BRENDA team
isoform hCE1
SwissProt
Manually annotated by BRENDA team
isoform hCE2
SwissProt
Manually annotated by BRENDA team
isoform hiCE
-
-
Manually annotated by BRENDA team
isoform hiCE
SwissProt
Manually annotated by BRENDA team
isoform hormone-sensitive lipase
-
-
Manually annotated by BRENDA team
isoforms hCE-1 and hCE-2, recombinant enzymes
SwissProt
Manually annotated by BRENDA team
isoforms hCE1 and hCE2
-
-
Manually annotated by BRENDA team
isoforms hCE1 and hiCE
SwissProt
Manually annotated by BRENDA team
isoforms hCE1, hCE2
-
-
Manually annotated by BRENDA team
isozymes CE-1 and CE-2
-
-
Manually annotated by BRENDA team
isozymes CE1 and intestinal CE
-
-
Manually annotated by BRENDA team
isozymes CES1 and CES2
-
-
Manually annotated by BRENDA team
Japanese population, gene CES2
-
-
Manually annotated by BRENDA team
monomeric and trimeric enzyme form
-
-
Manually annotated by BRENDA team
strain ZD112
SwissProt
Manually annotated by BRENDA team
strain ZD112
SwissProt
Manually annotated by BRENDA team
LILA, EstC
SwissProt
Manually annotated by BRENDA team
strain CL96
SwissProt
Manually annotated by BRENDA team
Lactobacillus casei CL96
strain CL96
SwissProt
Manually annotated by BRENDA team
Lactobacillus casei LILA EstC
LILA, EstC
SwissProt
Manually annotated by BRENDA team
Lactobacillus delbrueckii subsp. lactis MG1363 EstA
MG1363, EstA
-
-
Manually annotated by BRENDA team
ssp. cremoris, strain CNRZ253, EstA esterase
SwissProt
Manually annotated by BRENDA team
ssp. lactis, strain TIL46, EstA esterase
SwissProt
Manually annotated by BRENDA team
expression in baculoviral system
-
-
Manually annotated by BRENDA team
cultivar Royal Gala AO3
-
-
Manually annotated by BRENDA team
strain 7-1W, AKU 163
-
-
Manually annotated by BRENDA team
Microbacterium sp. 7-1W
strain 7-1W, AKU 163
-
-
Manually annotated by BRENDA team
strain YGJ1, isoforms E1 and E2
-
-
Manually annotated by BRENDA team
strain YGJ1, isoforms E1 and E2
-
-
Manually annotated by BRENDA team
expressed in baculoviral system
-
-
Manually annotated by BRENDA team
expressed in baculoviral system
SwissProt
Manually annotated by BRENDA team
isoform MT2282
-
-
Manually annotated by BRENDA team
protein Rv1399c, overexpressed in Escherichia coli
-
-
Manually annotated by BRENDA team
juvenile, after exposure to chlorpyrifos or esfenvalerate
-
-
Manually annotated by BRENDA team
isoform rCE
-
-
Manually annotated by BRENDA team
isoform rCE
SwissProt
Manually annotated by BRENDA team
isoform rCE1
SwissProt
Manually annotated by BRENDA team
monomeric and trimeric enzyme form
-
-
Manually annotated by BRENDA team
saw-toothed grain beetle, strains VOSCM and VOS48
-
-
Manually annotated by BRENDA team
ssp. shermanii, enzyme EstA, gene estA
-
-
Manually annotated by BRENDA team
isoform EstA
-
-
Manually annotated by BRENDA team
strain PAO1
-
-
Manually annotated by BRENDA team
strain KCTC1767
Uniprot
Manually annotated by BRENDA team
Pseudomonas fluorescens KCTC1767
strain KCTC1767
Uniprot
Manually annotated by BRENDA team
IFO12996
SwissProt
Manually annotated by BRENDA team
Pseudomonas putida IFO12996
IFO12996
SwissProt
Manually annotated by BRENDA team
strain B11-1, cold-adapted enzyme
SwissProt
Manually annotated by BRENDA team
strain KWI-56
-
-
Manually annotated by BRENDA team
strain B11-1, cold-adapted enzyme
SwissProt
Manually annotated by BRENDA team
strain KWI-56
-
-
Manually annotated by BRENDA team
strain Ant300
-
-
Manually annotated by BRENDA team
strain Ant300
-
-
Manually annotated by BRENDA team
4 independent lipolytic carboxylesterases
-
-
Manually annotated by BRENDA team
hydrolases A and B
-
-
Manually annotated by BRENDA team
isozyme CES2
SwissProt
Manually annotated by BRENDA team
male Sprague-Dawley rat, isoenzyme ES10, belonging to the nonspecific carboxylesterase family
SwissProt
Manually annotated by BRENDA team
male Sprague-Dawley rat, isoenzyme ES3, belonging to the nonspecific carboxylesterase family
SwissProt
Manually annotated by BRENDA team
male Sprague-Dawley rat, isoenzyme ES4, belonging to the nonspecific carboxylesterase family
SwissProt
Manually annotated by BRENDA team
male Sprague-Dawley rat, isoenzyme termed AB010635, belonging to the nonspecific carboxylesterase CES2 family
SwissProt
Manually annotated by BRENDA team
male Sprague-Dawley rat, isoenzyme termed AY034877, belonging to the nonspecific carboxylesterase CES2 family
Q8K3R0
SwissProt
Manually annotated by BRENDA team
male Sprague-Dawley rat, isoenzyme termed D50580 or CE21p, belonging to the nonspecific carboxylesterase family
SwissProt
Manually annotated by BRENDA team
eastern subterranean termite, workers, 3 isozymes ME1, ME2, and ME3, which are B type serine esterases
-
-
Manually annotated by BRENDA team
strain SES-01, gene bioHs
UniProt
Manually annotated by BRENDA team
strain SES-01, gene bioHs
UniProt
Manually annotated by BRENDA team
subspecies Streptococcus equi equi
B5THG6
UniProt
Manually annotated by BRENDA team
DSM5389; strain DSM5389, expression in Escherichia coli
-
-
Manually annotated by BRENDA team
Sulfolobus shibatae DSM5389
DSM5389; strain DSM5389, expression in Escherichia coli
-
-
Manually annotated by BRENDA team
fragment; strain P1
-
-
Manually annotated by BRENDA team
isoform EST2
-
-
Manually annotated by BRENDA team
strain P1, enzyme Est1
-
-
Manually annotated by BRENDA team
Sulfolobus solfataricus DSM 1617
-
-
-
Manually annotated by BRENDA team
Sulfolobus solfataricus MT4
strain MT4
-
-
Manually annotated by BRENDA team
Sulfolobus solfataricus P1
-
-
-
Manually annotated by BRENDA team
Sulfolobus solfataricus P1
-
UniProt
Manually annotated by BRENDA team
Sulfolobus solfataricus P1
fragment; strain P1
-
-
Manually annotated by BRENDA team
Sulfolobus solfataricus P1
strain P1
-
-
Manually annotated by BRENDA team
Sulfolobus solfataricus P1
strain P1, enzyme Est1
-
-
Manually annotated by BRENDA team
; strain 7
SwissProt
Manually annotated by BRENDA team
Sulfolobus tokodaii 7
-
SwissProt
Manually annotated by BRENDA team
Sulfolobus tokodaii 7
-
UniProt
Manually annotated by BRENDA team
Sulfolobus tokodaii 7
; strain 7
SwissProt
Manually annotated by BRENDA team
commercial product
-
-
Manually annotated by BRENDA team
enzyme contains the GGGX sequence motif
-
-
Manually annotated by BRENDA team
isoenzyme carboxylase 1
-
-
Manually annotated by BRENDA team
isoenzyme I and V
-
-
Manually annotated by BRENDA team
isoform gamma-rPLE
-
-
Manually annotated by BRENDA team
minipig
-
-
Manually annotated by BRENDA team
PLE
-
-
Manually annotated by BRENDA team
Sus scrofa PLE
PLE
-
-
Manually annotated by BRENDA team
Thalassobacillus sp.
-
-
-
Manually annotated by BRENDA team
Thermobifida fusca KW3
-
-
-
Manually annotated by BRENDA team
flour beetle, 2 strains, one is resistant to insecticide malathion possissing a malathion carboxylesterase, the other is suceptible to malathion possessing a non-specific carboxylesterase
-
-
Manually annotated by BRENDA team
Trichosporon sp.
strain DSMZ 11829
-
-
Manually annotated by BRENDA team
enzyme EstA3, isolated from drinking water genome
-
-
Manually annotated by BRENDA team
isoform EstE1, organism isolated from a thermal environmental sample
-
-
Manually annotated by BRENDA team
enzyme EstCE1, isolated from soil metagenome
-
-
Manually annotated by BRENDA team
analysis of alpha- and beta-esterase polymorphisms in different cultivars. alpha-Carboxylesterase EST-3 is absent in 61.7% of vines
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
malfunction
-
the knockdown of CES1 with siRNA results in lower levels of hepatitis C virus replication (reduction in hepatitis C virus RNA and NS3 and NS5A proteins by 80, 50, and 75%, respectively, up to 72 h post-transfection)
malfunction
-
underexpression by knockout mutation and/or RNAi-mediated silencing of multiple AtMES genes, including AtMES1, -2, -7, and -9, compromises systemic acquired resistance in Arabidopsis and correlated with enhanced accumulation of MeSA in the systemic tissue of systemic acquired resistance-induced plants
malfunction
Q9SG92
methyl 1H-indole-3-carboxylate exerts inhibitory activity on the growth of wild-type roots when applied exogenously. However, the roots of Arabidopsis plants carrying T-DNA insertions in the putative MeIAA esterase gene AtMES17 displays significantly decreased sensitivity to indole-3-acetic acid methyl ester compared with wild-type roots while remaining as sensitive to free indole.3.acetic acid as wild-type roots
physiological function
-
carboxylesterases are involved in lipid homeostasis, including cholesterol metabolism and transport with a proposed role in the development of atherosclerosis
physiological function
-
CES1 plays a role in the metabolism and detoxification of many compounds
physiological function
-
carboxylesterase from the chlorpyrifos-methyl-resistant strain VOSCM of Oryzaephilus surinamensis plays a role in conferring resistance to chlorpyrifos-methyl
physiological function
-
hepatic carboxylesterase CE1 plays a significant role in CPT-11 hydrolysis even though it is up to 100fold less efficient at drug activation than intestinal carboxylesterase. The drug activation in the intestine and kidney are likely major contributors to SN-38 production in vivo
physiological function
-
up-regulation of CES1 is observed to favor hepatitis C virus propagation implying an important role for this host cell protein. CES1 activity is observed to increase the size and density of lipid droplets, which are necessary for the maturation of very low density lipoproteins, one of the likely vehicles for hepatitis C virus release. CES1 increases triacylglycerol and cholesteryl ester levels and apolipoprotein B secretion
physiological function
-
CXE1 has an impact on apple flavour through its ability to hydrolyse relevant flavour esters in ripe apple fruit
physiological function
-
in antennae, CXE10 expression is associated with sensilla responding to the sex pheromones and to plant odours
physiological function
-
SABP2's methyl salicylate esterase activity is required in healthy systemic tissues of infected plants to release the active defense phytohormone SA from methyl salicylate, which serves as a long-distance signal for systemic acquired resistance
physiological function
Q9SG92
indole-3-acetic acid methyl ester, i.e. methyl 1H-indole-3-carboxylate, is an inactive form of indole-3-acetic acid, and the manifestations of indole-3-acetic acid methyl ester in vivo activity are due to the action of free indole-3-acetic acid that is generated from indole-3-acetic acid methyl ester upon hydrolysis by one or more plant esterases
metabolism
-
CES1 does not influence the mevalonate pathway
additional information
-
BioHe also functions as a pimeloyl-CoA thioesterase/acyltransferase for the biotin synthetic pathway
additional information
B0M0H6
BioHs also functions as a pimeloyl-CoA thioesterase/acyltransferase for the biotin synthetic pathway
additional information
-
of 14 recombinant methyl esterase proteins tested, five show preference for methyl salicylate as a substrate and display salicylate inhibition of methyl salicylate esterase activity in vitro, i.e. AtMES1, -2, -4, -7, and -9
additional information
-
BioHs also functions as a pimeloyl-CoA thioesterase/acyltransferase for the biotin synthetic pathway
-
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(+)-1,2-O-isopropylidenglycerol caprylate + H2O
(+)-1,2-O-isopropylidenglycerol + caprylate
show the reaction diagram
Bacillus subtilis, Bacillus subtilis 168, Bacillus subtilis Thai I-8
-
-
-
-
?
(+)-menthylacetate + H2O
(+)-menthol + acetate
show the reaction diagram
-
enzyme is highly enantioselective for (+)-menthylacetate
-
-
?
(+)-trans 4-nitrophenyl crysanthemate + H2O
(+)-trans-crysanthemic acid + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
(+)-trans-ethyl crysanthemate + H2O
(+)-trans crysanthemic acid + ethanol
show the reaction diagram
-
-
-
-
?
(+/-)-1,2-O-isopropylidenglycerol butanoate + H2O
(+/-)-1,2-O-isopropylidenglycerol + butanoate
show the reaction diagram
-
-, no substrate for isoform CesB
-
-
?
(+/-)-1,2-O-isopropylidenglycerol butanoate + H2O
(+/-)-1,2-O-isopropylidenglycerol + butanoate
show the reaction diagram
Bacillus subtilis 168
-
-, no substrate for isoform CesB
-
-
?
(+/-)-1,2-O-isopropylidenglycerol butanoate + H2O
(+/-)-1,2-O-isopropylidenglycerol + butanoate
show the reaction diagram
Bacillus subtilis Thai I-8
-
-, no substrate for isoform CesB
-
-
?
(-)-1,2-O-isopropylidenglycerol caprylate + H2O
(-)-1,2-O-isopropylidenglycerol + caprylate
show the reaction diagram
-
-, no substrate for isoform CesB
-
-
?
(-)-1,2-O-isopropylidenglycerol caprylate + H2O
(-)-1,2-O-isopropylidenglycerol + caprylate
show the reaction diagram
Bacillus subtilis 168, Bacillus subtilis Thai I-8
-
-
-
-
?
(1R)-bioresmethrin + H2O
?
show the reaction diagram
-
-
-
-
?
(1R)-bioresmethrin + H2O
?
show the reaction diagram
-
substrate for isoform hCE1, not for hCE2
-
-
?
(1RS)-cis-permethrin + H2O
cis-dichlorochrysamthemic acid + 3-phenoxybenzyl alcohol
show the reaction diagram
-
-
-
-
?
(1RS)-cis-permethrin + H2O
cis-dichlorochrysamthemic acid + 3-phenoxybenzyl alcohol
show the reaction diagram
-
isoforms hCE1 and hCE2 hydrolyze trans-permethrin 8- and 28fold more efficiently than cis-permethrin, resp.
-
-
?
(1RS)-trans-permethrin + H2O
trans-dichlorochrysamthemic acid + 3-phenoxybenzyl alcohol
show the reaction diagram
-
-
-
-
?
(1RS)-trans-permethrin + H2O
trans-dichlorochrysamthemic acid + 3-phenoxybenzyl alcohol
show the reaction diagram
-
isoforms hCE1 and hCE2 hydrolyze trans-permethrin 8- and 28fold more efficiently than cis-permethrin, resp.
-
-
?
(2R)-fenvalerate + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
(2S)-fenvalerate + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
(alphaR)(2R)-fenvalerate + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
(alphaR)(2S)-fenvalerate + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
(alphaS)(2R)-fenvalerate + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
(R)-2-(3-benzoylphenyl)propanoic methyl ester + H2O
methanol + (R)-2-(3-benzoylphenyl)propanoate
show the reaction diagram
-
when tested with the racemic substrate, the enzyme leads to the production of the R-configured acid with an enantiomeric excess of 80% at the conversion rate of 20% in 32 h
-
-
?
(R)-cyano(6-methoxy-2-naphthyl)methyl (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
(R)-cyano(6-methoxy-2-naphthyl)methyl (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
(R)-cyano(6-methoxy-2-naphthyl)methyl (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
(R)-cyano(6-methoxy-2-naphthyl)methyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
(R)-cyano(6-methoxynaphthalen-2-yl)methyl (2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (2R)-2-(4-chlorophenyl)-3-methylbutanoic acid
show the reaction diagram
P23141
-
-
-
?
(R)-naproxen methyl ester + H2O
(R)-naproxen + methanol
show the reaction diagram
-
-
-
-
?
(S)-1-(6-fluoro-2-methyl-3,4-dihydroquinolin-1(2H)-yl)-2-(isoquinolin-5-yloxy)ethanone + H2O
(2S)-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline + (isoquinolin-5-yloxy)acetic acid
show the reaction diagram
-
-
-
-
?
(S)-1-(6-fluoro-2-methyl-3,4-dihydroquinolin-1(2H)-yl)-2-(isoquinolin-5-yloxy)ethanone + H2O
(2S)-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline + (isoquinolin-5-yloxy)acetic acid
show the reaction diagram
-
cleavage of the amide bond, inhibited by bis(p-nitrophenyl) phosphate
-
-
?
(S)-cyano(6-methoxy-2-naphthyl)methyl (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
(S)-cyano(6-methoxy-2-naphthyl)methyl (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
(S)-cyano(6-methoxy-2-naphthyl)methyl (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
(S)-cyano(6-methoxy-2-naphthyl)methyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (2S)-2-(4-chlorophenyl)-3-methylbutanoic acid
show the reaction diagram
P23141
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (2S)-2-(4-chlorophenyl)-3-methylbutanoic acid
show the reaction diagram
P23141
-
-
-
?
(S)-ibuprofen methyl ester + H2O
(S)-ibuprofen + methanol
show the reaction diagram
Sulfolobus solfataricus, Sulfolobus solfataricus DSM 1617
-
the enzyme has S-form specificity for ibuprofen
-
-
?
(S)-ketoprofen ethyl ester + H2O
(S)-ketoprofen + ethanol
show the reaction diagram
Q8VU79
enantioselective activity, best substrate
-
?
(S)-naproxen methyl ester + H2O
(S)-naproxen + methanol
show the reaction diagram
-
-
-
-
?
(S)-naproxen methyl ester + H2O
(S)-naproxen + methanol
show the reaction diagram
D0EPY0
-
i.e. (+)-(S)-2-(6-methoxy-2-naphthyl)propionic acid, 98% enantiomeric excess
-
?
(S)-naproxen methyl ester + H2O
(S)-naproxen + methanol
show the reaction diagram
Sulfolobus solfataricus, Sulfolobus solfataricus P1
-
the enzyme yields highly optically pure (S) naproxen
-
-
?
(Z)-3-hexenyl acetate + H2O
(Z)-3-hexenol + acetate
show the reaction diagram
-
nearly 100% hydrolysis (native enzyme), 89.2% hydrolysis (recombinant enzyme)
-
-
?
(Z9,E11)-tetradec-9,11-enyl acetate + H2O
(Z9,E11)-tetradec-9,11-en-1-ol + acetate
show the reaction diagram
-
about 40% hydrolysis (native enzyme), 7.63% hydrolysis (recombinant enzyme)
-
-
?
(Z9,E12)-tetradec-9,12-enyl acetate + H2O
(Z9,E11)-tetradec-9,12-en-1-ol + acetate
show the reaction diagram
-
about 40% hydrolysis (native enzyme), 8.98% hydrolysis (recombinant enzyme)
-
-
?
1,2-dioctanoyl-glycerol + H2O
octanoate + glycerol
show the reaction diagram
-
-
-
-
-
1,2-O-dilauryl-rac-glycero-3-glutaric acid-resorufin ester + H2O
?
show the reaction diagram
O73957
-
-
-
?
1,3-dioctanoyl-glycerol + H2O
octanoate + glycerol
show the reaction diagram
-
-
-
-
?
1-chloro-3-(1-naphthyloxy)-2-propanol acylester + H2O
(R)-1-chloro-3-(1-naphthyloxy)-2-propanol + carboxylic acid
show the reaction diagram
Trichosporon sp.
-
-
high stereoselectivity
-
?
1-monocaprylylglycerol + H2O
caprylic acid + glycerol
show the reaction diagram
-
-
-
-
?
1-monocaprylylglycerol + H2O
caprylic acid + glycerol
show the reaction diagram
-
27% of the activity with tributyrin
-
-
?
1-monodecanoyl-glycerol + H2O
decanoate + glycerol
show the reaction diagram
-
-
-
-
-
1-monolauroyl-glycerol + H2O
lauric acid + glycerol
show the reaction diagram
-
-
-
-
?
1-monolauroyl-glycerol + H2O
lauric acid + glycerol
show the reaction diagram
-
10.0% of the activity with tributyrin
-
-
?
1-monomyristoyl-glycerol + H2O
myristic acid + glycerol
show the reaction diagram
-
-
-
-
-
1-monomyristoyl-glycerol + H2O
myristic acid + glycerol
show the reaction diagram
-
11.6% of the activity with tributyrin
-
-
?
1-monooctanoyl-glycerol + H2O
octanoate + glycerol
show the reaction diagram
-
-
-
-
?
1-monooleyl glycerol + H2O
oleic acid + glycerol
show the reaction diagram
-
-
-
-
?
1-monopalmitin + H2O
palmitic acid + glycerol
show the reaction diagram
-
3.8% of the activity with tributyrin
-
-
?
1-monostearin + H2O
stearic acid + glycerol
show the reaction diagram
-
1.6% of the activity with tributyrin
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
Thalassobacillus sp.
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
Geobacillus stearothermophilus CICC 20156
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
Escherichia coli HB17
-
-
-
-
?
1-naphthyl butanoate + H2O
1-naphthol + butanoate
show the reaction diagram
-
-
-
-
?
1-naphthyl butanoate + H2O
1-naphthol + butanoate
show the reaction diagram
-
54% of the activity with 1-naphthyl acetate
-
-
?
1-naphthyl butyrate + H2O
1-naphthol + butyrate
show the reaction diagram
-
-
-
-
?
1-naphthyl butyrate + H2O
1-naphthol + butyrate
show the reaction diagram
-
-
-
-
?
1-naphthyl butyrate + H2O
1-naphthol + butyrate
show the reaction diagram
-
-
-
-
?
1-naphthyl butyrate + H2O
1-naphthol + butyrate
show the reaction diagram
Escherichia coli HB17
-
-
-
-
?
1-naphthyl caprylate + H2O
1-naphthol + caprylate
show the reaction diagram
-
14% of the activity with 1-naphthyl acetate
-
-
?
1-naphthyl laurate + H2O
1-naphthol + laurate
show the reaction diagram
-
9% of the activity with 1-naphthyl acetate
-
-
?
1-naphthyl oleate + H2O
1-naphthol + oleate
show the reaction diagram
-
2% of the activity with 1-naphthyl acetate
-
-
?
1-naphthyl propionate + H2O
1-naphthol + propionate
show the reaction diagram
-
-
-
-
?
1-naphthyl propionate + H2O
1-naphthol + propionate
show the reaction diagram
-
-
-
-
?
1-naphthyl propionate + H2O
1-naphthol + propionate
show the reaction diagram
-
-
-
-
?
1-naphthyl propionate + H2O
1-naphthol + propionate
show the reaction diagram
Escherichia coli HB17
-
-
-
-
?
2'-ethylcarbonate-linked paclitaxel + H2O
paclitaxel + propanoate
show the reaction diagram
-
-
-
-
?
2,4-dinitrophenyl butyrate + H2O
2,4-dinitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
2,4-dinitrophenyl butyrate + H2O
2,4-dinitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
2-acetoxy-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine + H2O
2-[2-oxo-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone + ?
show the reaction diagram
-
also called prasugrel, the hydrolysis is at least 25times greater with CE2 than CE1
also called R-95913
-
?
2-deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine + H2O
decitabine + ?
show the reaction diagram
-
-
-
-
?
2-monopalmitin + H2O
palmitic acid + glycerol
show the reaction diagram
-
2.6% of the activity with tributyrin
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
Thalassobacillus sp.
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
Bacillus subtilis 168, Bacillus subtilis Thai I-8
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
Sulfolobus solfataricus MT4
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
-
-
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
Escherichia coli HB17
-
-
-
-
?
2-naphthyl butyrate + H2O
2-naphthol + butyrate
show the reaction diagram
-
-
-
-
?
2-naphthyl propionate + H2O
2-naphthol + propionate
show the reaction diagram
-
-
-
-
?
2-naphthyl propionate + H2O
2-naphthol + propionate
show the reaction diagram
-
-
-
-
?
2-naphthyl propionate + H2O
2-naphthol + propionate
show the reaction diagram
Escherichia coli HB17
-
-
-
-
?
2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
show the reaction diagram
P23141
-
-
-
?
2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
show the reaction diagram
O00748
-
-
-
?
2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
show the reaction diagram
P23141
-
-
-
?
2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
show the reaction diagram
P12337
-
-
-
?
2-nitrophenyl butyrate + H2O
2-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
2-nitrophenyl butyrate + H2O
2-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
-
2-nitrophenyl butyrate + H2O
2-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
2-nitrophenyl butyrate + H2O
2-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
2-nitrophenyl butyrate + H2O
2-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
2-nitrophenyl butyrate + H2O
2-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
2-nitrophenyl laurate + H2O
2-nitrophenol + laurate
show the reaction diagram
-
-
-
-
?
2-nitrophenylpropionate + H2O
2-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
2-phenyl-3-butyn-2-yl acetate
2-phenyl-3-butyn-2-ol + acetate
show the reaction diagram
-, P37967
-
-
-
-
2-phenyl-3-butyn-2-yl acetate + H2O
2-phenyl-3-butyn-2-ol + acetate
show the reaction diagram
-
model substrate for study of enantioselectivity in the enzyme reaction, low enantioselectivity, overview
-
?
2-phenyl-3-butyn-2-yl acetate + H2O
2-phenyl-3-butyn-2-ol + acetate
show the reaction diagram
-
model substrate for study of enantioselectivity in the enzyme reaction, overview
-
?
2-phenyloxazolin-5-one + H2O
?
show the reaction diagram
-
-
-
-
?
3'-D-phenylalanyl-gemcitabine + H2O
D-phenylalanine + gemcitabine
show the reaction diagram
-
-
-
-
?
3'-D-valyl-gemcitabine + H2O
D-valine + gemcitabine
show the reaction diagram
-
-
-
-
?
3'-L-isoleucyl-gemcitabine + H2O
L-isoleucine + gemcitabine
show the reaction diagram
-
-
-
-
?
3'-L-phenylalanyl-gemcitabine + H2O
L-phenylalanine + gemcitabine
show the reaction diagram
-
-
-
-
?
3'-L-valyl-gemcitabine + H2O
L-valine + gemcitabine
show the reaction diagram
-
-
-
-
?
3-methyl-1-pentyn-3-yl acetate + H2O
3-methyl-1-pentyn-3-ol + acetate
show the reaction diagram
-, P37967
-
-
-
?
3-methyl-1-pentyn-3-yl acetate + H2O
3-methyl-1-pentyn-3-ol + acetate
show the reaction diagram
-
model substrate for study of enantioselectivity in the enzyme reaction, low enantioselectivity, overview
-
?
3-methyl-1-pentyn-3-yl acetate + H2O
3-methyl-1-pentyn-3-ol + acetate
show the reaction diagram
-
model substrate for study of enantioselectivity in the enzyme reaction, no enantioselectivity by the wild-type enzyme, overview
-
?
3-nitrophenyl butyrate + H2O
3-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
3-nitrophenyl butyrate + H2O
3-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
3-phenoxybenzyl (1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
-
i.e. 1R-cis-NRDC157
-
-
?
3-phenoxybenzyl (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
-
i.e. 1R-trans-permethrin, strong chiral preference for the 1S over the 1R isomers of permethrin
-
-
?
3-phenoxybenzyl (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
-
i.e. 1S-trans-permethrin, strong chiral preference for the 1S over the 1R isomers of permethrin
-
-
?
3-phenoxybenzyl (1S,3S)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,3S)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
-
i.e. 1S-cis-NRDC157
-
-
?
4-aminobenzoic acid butyl ester + H2O
4-aminobenzoic acid + butanol
show the reaction diagram
-
-
-
-
?
4-aminobenzoic acid ethyl ester + H2O
4-aminobenzoic acid + ethanol
show the reaction diagram
-
-
-
-
?
4-aminobenzoic acid propyl ester + H2O
4-aminobenzoic acid + propanol
show the reaction diagram
-
-
-
-
?
4-methylumbelliferone acetate + H2O
?
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl (2E)-but-2-enoate + H2O
4-methylumbelliferone + (2E)-but-2-enoic acid
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl 3-phenoxybutanoate + H2O
4-methylumbelliferone + 3-phenoxybutanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
O35535, O70631, P16303, Q63108, Q64573, Q8K3R0
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
Sulfolobus solfataricus DSM 1617
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
Sulfolobus solfataricus P1
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferol + acetate
show the reaction diagram
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferol + acetate
show the reaction diagram
-, Q0ZPV7
-
-
-
?
4-methylumbelliferyl butanoate + H2O
4-methylumbelliferol + butanoate
show the reaction diagram
-
enzyme activity in decreasing order: 4-methylumbelliferyl butanoate, 4-methylumbelliferyl heptanoate, 4-methylumbelliferyl oleate
-
-
?
4-methylumbelliferyl butanoate + H2O
4-methylumbelliferone + butanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferone + butyrate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferone + butyrate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferone + butyrate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferone + butyrate
show the reaction diagram
-
hydrolysis is 50% compared to 4-methylumbelliferyl acetate
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferone + butyrate
show the reaction diagram
Sulfolobus solfataricus P1
-
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferol + butyrate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferol + butyrate
show the reaction diagram
-, Q0ZPV7
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferol + butyrate
show the reaction diagram
-, Q9LAB8
high activity
-
?
4-methylumbelliferyl cyclopentane carboxylate + H2O
4-methylumbelliferone + cyclopentane carboxylate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl heptanoate + H2O
4-methylumbelliferol + heptanoate
show the reaction diagram
-, Q0ZPV7
-
-
-
?
4-methylumbelliferyl heptanoate + H2O
4-methylumbelliferol + heptanoate
show the reaction diagram
-
enzyme activity in decreasing order: 4-methylumbelliferyl butanoate, 4-methylumbelliferyl heptanoate, 4-methylumbelliferyl oleate
-
-
?
4-methylumbelliferyl heptanoate + H2O
4-methylumbelliferone + heptanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl hexanoate + H2O
4-methylumbelliferone + hexanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl laurate + H2O
4-methylumbelliferol + laurate
show the reaction diagram
-, Q0ZPV7
-
-
-
?
4-methylumbelliferyl laurate + H2O
4-methylumbelliferone + laurate
show the reaction diagram
-
best substrate
-
-
?
4-methylumbelliferyl octanoate + H2O
4-methylumbelliferol + octanoate
show the reaction diagram
-, Q0ZPV7
-
-
-
?
4-methylumbelliferyl octanoate + H2O
4-methylumbelliferone + octanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl octanoate + H2O
4-methylumbelliferone + octanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl oleate + H2O
4-methylumbelliferol + oleate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl oleate + H2O
4-methylumbelliferol + oleate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl oleate + H2O
4-methylumbelliferol + oleate
show the reaction diagram
-
enzyme activity in decreasing order: 4-methylumbelliferyl butanoate, 4-methylumbelliferyl heptanoate, 4-methylumbelliferyl oleate
-
-
?
4-methylumbelliferyl p-trimethylammoniocinnamate chloride + H2O
4-methylumbelliferol + p-trimethylammoniocinnamate chloride
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl palmitate + H2O
4-methylumbelliferol + palmitate
show the reaction diagram
-, Q0ZPV7
-
-
-
?
4-methylumbelliferyl palmitate + H2O
4-methylumbelliferone + palmitate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl palmitate + H2O
4-methylumbelliferone + palmitate
show the reaction diagram
-
hydrolysis is 7% compared to 4-methylumbelliferyl acetate
-
-
?
4-methylumbelliferyl pentanoate + H2O
4-methylumbelliferone + pentanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl propionate + H2O
4-methylumbelliferone + propionate
show the reaction diagram
-
-
-
-
?
4-nitrobenzoic acid methyl ester + H2O
4-nitrobenzoic acid + methanol
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 5.5
-
-
?
4-nitrophenyl 2-chloropropionate + H2O
4-nitrophenol + (S)-2-chloropropionic acid
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-, Q8BK48
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
P23141
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q8VU79
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
-
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
r
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-, Q8KT44
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-, Q8GR22
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-, Q52NW7
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q840T2
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q7M529, -
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-, O76177
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
B5THG6, -
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
B0M0H6
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q97VU1, -
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q97VW1
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q4PNS3
-
92% of the activity with 4-nitrophenyl butanoate
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-, P13001
best substrate
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
best substrate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
Est55, 30% of the activity with 4-nitrophenyl butanoate, Est30, 20% of the activity with 4-nitrophenyl caproate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
15% of the activity with 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q7M529, -
8.8% of the activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
at 37C, 14% of the activity with pentanoyl-CoA
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 2.1
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Thalassobacillus sp.
-
89% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
D0EPY0
about 30% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
substrate for both isoform CES1 and CES2
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
specific activity is less than 10% compared to the activity with caprylate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
hydrolysis at about 70% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q976W8
the acyl-length selectivity of the proteins against 4-nitrophenyl ester substrates in the order of decreasing efficiency: C8, C6, C4, C3, C2
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Sus scrofa PLE
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Bacillus subtilis ECU0554
D0EPY0
about 30% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q52NW7
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Sulfolobus tokodaii 7
Q96Z02
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Sulfolobus tokodaii 7
Q976W8
the acyl-length selectivity of the proteins against 4-nitrophenyl ester substrates in the order of decreasing efficiency: C8, C6, C4, C3, C2
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Aspergillus nomius HS-1
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Arthrobacter viscosus NRRL B-1973
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Lactobacillus casei CL96
Q840T2
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q8GR22
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Sulfolobus solfataricus MT4
-
at 37C, 14% of the activity with pentanoyl-CoA
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Emericella nidulans PW1
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Geobacillus stearothermophilus CICC 20156
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
89% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Bacillus subtilis SR22
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Sulfolobus shibatae DSM5389
-
15% of the activity with 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
B0M0H6
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
specific activity is less than 10% compared to the activity with caprylate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q97VU1
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Q97VW1, -
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
-
hydrolysis at about 70% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Lactobacillus delbrueckii subsp. lactis MG1363 EstA
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Arthrobacter globiformis SC-69828
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Enterobacter cloacae EM
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
Lactobacillus casei LILA EstC
Q8KT44
-
-
?
4-nitrophenyl acetate + H2O
4 nitrophenol + acetate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl acetate + H2O
4.nitrophenol + acetate
show the reaction diagram
-
converted twice as fast as the corresponding palmitate
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
-
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
-
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
Q840T2
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
Q976W8, -
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
Q4PNS3
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
F0NDQ1, -
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-, Q8KT44
best substrate
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
best substrate of mutants M211V, M211T, M211S and M211S/R215L
-
r
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
Est30, 65% of the activity with 4-nitrophenyl caproate
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
Q7M529, -
83% of the activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
hydrolysis at about 90% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
Sulfolobus tokodaii, Sulfolobus tokodaii 7
Q976W8
the acyl-length selectivity of the proteins against 4-nitrophenyl ester substrates in the order of decreasing efficiency: C8, C6, C4, C3, C2
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
Lactobacillus casei CL96
Q840T2
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
Bacillus coagulans 81-11
-
-
-
-
-
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-, P13001
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q8VU79
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q89528, Q8KWI9
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-, Q8GR22
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-, Q52NW7
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q976W8, -
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
B0M0H6
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q97VU1, -
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
O28558
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
M5DDN2
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
O73957
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
highest activity
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
highest activity
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
weak
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
4-nitrophenyl propionate and 4-nitrophenyl butyrate are the best substrates
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
at 37C, 74% of the activity with pentanoyl-CoA
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
G3JWZ2, -
about 80% activity compared to 4-nitrophenyl caprylate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Anoxybacillus sp.
-
high level of activity with 4-nitrophenyl butyrate (100%)
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
D0EPY0
highest activity (100%)
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Thalassobacillus sp.
-
most efficient hydrolysis with 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
specific activity is about 80% compared to the activity with caprylate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q96Z02
most preferable substrate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Bacillus subtilis ECU0554
D0EPY0
highest activity (100%)
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q52NW7
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
O73957
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Sulfolobus tokodaii 7
Q96Z02
most preferable substrate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Sulfolobus tokodaii 7
Q976W8
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Sulfolobus tokodaii 7
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Aspergillus nomius HS-1
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Sulfolobus solfataricus DSM 1617
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Geobacillus thermodenitrificans CMB-A2
G3JWZ2
about 80% activity compared to 4-nitrophenyl caprylate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Acinetobacter lwoffii I6C-1
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q8GR22
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Sulfolobus solfataricus MT4
-
at 37C, 74% of the activity with pentanoyl-CoA
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
high level of activity with 4-nitrophenyl butyrate (100%)
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
most efficient hydrolysis with 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Sulfolobus shibatae DSM5389
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
B0M0H6
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Sulfolobus solfataricus P1
M5DDN2
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
-
specific activity is about 80% compared to the activity with caprylate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Q97VU1
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
Arthrobacter globiformis SC-69828
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4 nitrophenol + butyrate
show the reaction diagram
Q96Z02
most preferable substrate
-
-
?
4-nitrophenyl caprate + H2O
4-nitrophenol + capric acid
show the reaction diagram
-
-
-
-
?
4-nitrophenyl caprate + H2O
4-nitrophenol + capric acid
show the reaction diagram
Q840T2
-
-
-
?
4-nitrophenyl caprate + H2O
4-nitrophenol + capric acid
show the reaction diagram
-
Est55, 1.6% of the activity with 4-nitrophenyl butanoate, Est30, 32% of the activity with 4-nitrophenyl caproate
-
-
?
4-nitrophenyl caprate + H2O
4-nitrophenol + capric acid
show the reaction diagram
Lactobacillus casei CL96
Q840T2
-
-
-
?
4-nitrophenyl caprate + H2O
4-nitrophenol + caprate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-, P13001
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-, Q8GR22
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-, Q52NW7
-
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
Q840T2
-
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
Q4PNS3
-
65% of the activity with 4-nitrophenyl butanoate
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-
82% of the activity with 4-nitrophenyl butanoate
-
-
-
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
-
Est55, 97% of the activity with 4-nitrophenyl butanoate, activation energy 35.7 kJ/mol. Est30, activation energy 101.9 kJ/mol
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
D0EPY0
about 55% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
Q97VU1, -
the enzyme shows the highest activity with p-nitrophenyl caproate
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
Lactobacillus casei CL96
Q840T2
-
-
-
?
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
Bacillus coagulans 81-11
-
82% of the activity with 4-nitrophenyl butanoate
-
-
-
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
Q97VU1
the enzyme shows the highest activity with p-nitrophenyl caproate
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
Q8VU79
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-, Q8GR22
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-, Q52NW7
-
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
Q840T2
-
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
Q4PNS3
-
45% of the activity with 4-nitrophenyl butanoate
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-
highest activity
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
G3JWZ2, -
maximal activity
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-
Est55, 13% of the activity with 4-nitrophenyl butanoate, Est30, 50% of the activity with 4-nitrophenyl caproate
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-
the enzyme shows the highest specific activity with p-nitrophenyl caprylate
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
Geobacillus thermodenitrificans CMB-A2
G3JWZ2
maximal activity
-
-
?
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
-
the enzyme shows the highest specific activity with p-nitrophenyl caprylate
-
-
?
4-nitrophenyl chrysanthemate + H2O
4-nitrophenol + chrysanthemate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
-
-
r
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
M5DDN2
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
F0NDQ1, -
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
Q7M529, -
1.8% of the activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
Thalassobacillus sp.
-
14% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
G3JWZ2, -
65% activity compared to 4-nitrophenyl caprylate
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
D0EPY0
about 30% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
specific activity is about 50% compared to the activity with caprylate
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
hydrolysis at about 50% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
Sulfolobus tokodaii 7
Q96Z02
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
Geobacillus thermodenitrificans CMB-A2
G3JWZ2
65% activity compared to 4-nitrophenyl caprylate
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
Sulfolobus solfataricus P1
M5DDN2
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
-
specific activity is about 50% compared to the activity with caprylate
-
-
?
4-nitrophenyl decanoate + H2O
4 nitrophenol + decanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
-
-
-
r
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
M5DDN2
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
F0NDQ1, -
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
Q97VW1
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
Q7M529, -
0.8% of the activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
D0EPY0
about 20% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
Q97VU2, -
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
-
hydrolysis at about 30% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
Sulfolobus tokodaii 7
Q96Z02
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
F0NDQ1
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
Sulfolobus solfataricus P1
M5DDN2
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
Q97VU2
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
Q97VW1, -
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
-
hydrolysis at about 30% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl dodecanoate + H2O
4 nitrophenol + dodecanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl heptanoate + H2O
4-nitrophenol + heptanoate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl hexadecanoate + H2O
4-nitrophenol + hexadecanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexadecanoate + H2O
4-nitrophenol + hexadecanoate
show the reaction diagram
-
-
-
r
4-nitrophenyl hexadecanoate + H2O
4-nitrophenol + hexadecanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl hexadecanoate + H2O
4-nitrophenol + hexadecanoate
show the reaction diagram
Q97VW1
-
-
-
?
4-nitrophenyl hexadecanoate + H2O
4-nitrophenol + hexadecanoate
show the reaction diagram
-
hydrolysis at less than 10% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl hexadecanoate + H2O
4 nitrophenol + hexadecanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl hexadecanoate + H2O
4-nitrophenol + palmitate
show the reaction diagram
M5DDN2
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
-
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-, Q8KT44
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
O28558
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
M5DDN2
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
F0NDQ1, -
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q97VW1
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
best substrate
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
best substrate of the wild-type enzyme
-
r
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q976W8, -
31.6% of the activity with 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q7M529, -
75.4% of the activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
at 37C, 69% of the activity with pentanoyl-CoA
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Thalassobacillus sp.
-
78% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q976W8, -
31.5% of the activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q97VU2, -
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
hydrolysis at about 90% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q976W8
the acyl-length selectivity of the proteins against 4-nitrophenyl ester substrates in the order of decreasing efficiency: C8, C6, C4, C3, C2
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Sulfolobus tokodaii 7
Q976W8
31.6% of the activity with 4-nitrophenyl butyrate, 31.5% of the activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Sulfolobus tokodaii 7
Q976W8
the acyl-length selectivity of the proteins against 4-nitrophenyl ester substrates in the order of decreasing efficiency: C8, C6, C4, C3, C2
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
F0NDQ1
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Sulfolobus solfataricus P1
M5DDN2
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q97VU2
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Q97VW1, -
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
-
hydrolysis at about 90% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
Arthrobacter globiformis SC-69828
-
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + lauric acid
show the reaction diagram
-
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + lauric acid
show the reaction diagram
-
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + lauric acid
show the reaction diagram
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + lauric acid
show the reaction diagram
Q840T2
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + lauric acid
show the reaction diagram
-
Est55, 0.6% of the activity with 4-nitrophenyl butanoate, Est30, 12% of the activity with 4-nitrophenyl caproate
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + lauric acid
show the reaction diagram
Lactobacillus casei CL96
Q840T2
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-, P13001
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-, Q8GR22
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-, Q52NW7
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
Q97VU1, -
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
Q4PNS3
-
30-35% of the activity with 4-nitrophenyl butanoate
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
Anoxybacillus sp.
-
37% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
G3JWZ2, -
58% activity compared to 4-nitrophenyl caprylate
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-
specific activity is about 10% compared to the activity with caprylate
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-
37% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
-
specific activity is about 10% compared to the activity with caprylate
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
Q97VU1
-
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristic acid
show the reaction diagram
-
-
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristic acid
show the reaction diagram
-
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
show the reaction diagram
G3JWZ2, -
36% activity compared to 4-nitrophenyl caprylate
-
-
?
4-nitrophenyl nonanoate + H2O
4-nitrophenol + nonanoate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
-
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
r
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
O28558
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
M5DDN2
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
F0NDQ1, -
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Q7M529, -
11.5% of the activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Q976W8, -
16.7% of the activity with 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Thalassobacillus sp.
-
46% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
D0EPY0
about 45% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Q976W8, -
16.7% of the activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
hydrolysis at about 75% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Q976W8
the acyl-length selectivity of the proteins against 4-nitrophenyl ester substrates in the order of decreasing efficiency: C8, C6, C4, C3, C2
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Bacillus subtilis ECU0554
D0EPY0
about 45% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Sulfolobus tokodaii 7
Q96Z02
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Sulfolobus tokodaii 7
Q976W8
16.7% of the activity with 4-nitrophenyl butyrate, 16.7% of the activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Sulfolobus tokodaii 7
Q976W8
the acyl-length selectivity of the proteins against 4-nitrophenyl ester substrates in the order of decreasing efficiency: C8, C6, C4, C3, C2
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
F0NDQ1
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Sulfolobus solfataricus P1
M5DDN2
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
-
hydrolysis at about 75% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
Arthrobacter globiformis SC-69828
-
-
-
-
?
4-nitrophenyl octanoate + H2O
4 nitrophenol + octanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitic acid
show the reaction diagram
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
-, Q8GR22
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
O28511
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
F0NDQ1, -
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
Q8VU79
low activity
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
-
low activity
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
G3JWZ2, -
12% activity compared to 4-nitrophenyl caprylate
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
Anoxybacillus sp., Anoxybacillus sp. PDF1
-
5% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
Sulfolobus solfataricus P1
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-, Q8KT44
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
Q7M529, -
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
O28558
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
F0NDQ1, -
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
Q97VW1
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
79% of the activity with 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
Sulfolobus solfataricus MT4
-
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
F0NDQ1
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
Q97VW1, -
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propanoate + H2O
4-nitrophenol + propanoate
show the reaction diagram
-
Est55, 50% of the activity with 4-nitrophenyl butanoate, Est30, 45% of the activity with 4-nitrophenyl caproate
-
-
?
4-nitrophenyl propanoate + H2O
4-nitrophenol + propanoate
show the reaction diagram
-
hydrolysis at about 85% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl propanoate + H2O
4-nitrophenol + propanoate
show the reaction diagram
Sulfolobus tokodaii, Sulfolobus tokodaii 7
Q976W8
the acyl-length selectivity of the proteins against 4-nitrophenyl ester substrates in the order of decreasing efficiency: C8, C6, C4, C3, C2
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-, P13001
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-, Q8KT44
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-, Q52NW7
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
O28558
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
-
77% of the activity with 4-nitrophenyl butanoate
-
-
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
-
4-nitrophenyl propionate and 4-nitrophenyl butyrate are the best substrates
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Q7M529, -
18% of the activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Bacillus subtilis, Bacillus subtilis ECU0554
D0EPY0
about 70% activity compared to 4-nitrophenyl butyrate
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Q52NW7
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Aspergillus nomius HS-1
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Arthrobacter viscosus NRRL B-1973
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Bacillus coagulans 81-11
-
-
77% of the activity with 4-nitrophenyl butanoate
-
-
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Lactobacillus delbrueckii subsp. lactis MG1363 EstA
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Arthrobacter globiformis SC-69828
-
-
-
-
?
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
Lactobacillus casei LILA EstC
Q8KT44
-
-
?
4-nitrophenyl stearate + H2O
4-nitrophenol + stearate
show the reaction diagram
Q9HXE7
-
-
-
?
4-nitrophenyl tetradecanoate + H2O
4-nitrophenol + tetradecanoate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl tetradecanoate + H2O
4-nitrophenol + tetradecanoate
show the reaction diagram
-
-
-
r
4-nitrophenyl tetradecanoate + H2O
4-nitrophenol + tetradecanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl tetradecanoate + H2O
4-nitrophenol + tetradecanoate
show the reaction diagram
-
hydrolysis at less tha 10% compared to activity with 4-nitrophenyl pentanoate
-
-
?
4-nitrophenyl tetradecanoate + H2O
4 nitrophenol + tetradecanoate
show the reaction diagram
Q96Z02
-
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-, Q8GR22
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-
high activity
-
-
?
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
-
-
-
-
?
5'-cinnamic acid-floxuridine + H2O
cinnamic acid + floxuridine
show the reaction diagram
-
-
-
-
?
5'-D-phenylalanyl-2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole + H2O
D-phenylalanine + 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole
show the reaction diagram
-
-
-
-
?
5'-D-phenylalanyl-gemcitabine + H2O
D-phenylalanine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-D-valyl-gemcitabine + H2O
D-valine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-L-isoleucyl-gemcitabine + H2O
L-isoleucine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-L-phenylalanine-floxuridine + H2O
L-phenylalanine + floxuridine
show the reaction diagram
-
-
-
-
?
5'-L-phenylalanyl-2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole + H2O
L-phenylalanine + 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole
show the reaction diagram
-
-
-
-
?
5'-L-phenylalanyl-gemcitabine + H2O
L-phenylalanine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-L-valyl-gemcitabine + H2O
L-valine + gemcitabine
show the reaction diagram
-
-
-
-
?
6-methoxy-alpha-methyl-2-naphthaleneacetic acid methyl ester
(S)-naproxen + methanol
show the reaction diagram
Trichosporon sp.
-
i.e. naproxen methyl ester
high stereoselectivity
-
?
6-monoacetylmorphine + H2O
morphine + acetate
show the reaction diagram
-
hCE1 can metabolize the conversion of heroin to both 6-monoacetylmorphine and morphine. hCE1 is able to catalyze both reactions, but it is more efficient at the hydrolysis of heroin to 6-monoacetylmorphine, the first step of heroin metabolism
-
-
?
7-acetoxy-3-(2-benzothiazolyl)-4-cyanocoumarin + H2O
?
show the reaction diagram
-, Q9LAB8
low activity
-
?
7-amino cephalosporanic acid + H2O
?
show the reaction diagram
-
-
-
-
?
7-ethyl-10-(4-(1-piperidino)-1-amino)carbonyloxycampothecin + H2O
7-ethyl-10-hydroxycampothecin + 4-aminopiperidine-1-carboxylic acid
show the reaction diagram
-
i.e. NPC
-
-
?
7-ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxycampothecin + H2O
7-ethyl-10-hydroxycampothecin + 1,4'-bipiperidine-1'-carboxylic acid
show the reaction diagram
-
i.e. irinotecan, CPT-11
-
-
?
7-ethyl-10-(4-N-(5-aminopentanoic acid)-1-piperidino)carbonyloxycampothecin + H2O
7-ethyl-10-hydroxycampothecin + 4-((4-carboxybutyl)amino)piperidine-1-carboxylic acid
show the reaction diagram
-
i.e. APC
-
-
?
7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin + H2O
7-ethyl-10-hydroxycampothecin + ?
show the reaction diagram
-
i.e. irinotecan, CPT-11, prodrug
i.e. SN-38, topoisomerase inhibitor used in cancer therapy
-
?
7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin + H2O
7-ethyl-10-hydroxycampothecin + ?
show the reaction diagram
-
i.e. irinotecan, CPT-11, prodrug
i.e. SN-38, topoisomerase inhibitor used in cancer therapy
-
?
7-ethyl-10[4-(1-piperidino)-1-piperdino]carbonyloxy-camptothecin + H2O
7-ethyl-10-hydroxy-camptothecin + ?
show the reaction diagram
-
activation of the prodrug, i.e. CPT-11 or irinotecan, a commercial topoisomerase I inhibitor commonly used for treatment of colorectal tumors
i.e. SN-38
?
7-ethyl-10[4-(1-piperidino)-1-piperdino]carbonyloxy-camptothecin + H2O
7-ethyl-10-hydroxy-camptothecin + ?
show the reaction diagram
-
i.e. CPT-11 or irinotecan, a commercial topoisomerase I inhibitor commonly used for treatment of colorectal tumors
i.e. SN-38
?
7-ethyl-10[4-(1-piperidino)-1-piperdino]carbonyloxy-camptothecin + H2O
7-ethyl-10-hydroxy-camptothecin + ?
show the reaction diagram
-
isozyme CE-2 is responsible for activation of the prodrug
i.e. SN-38
?
7-[4-octylcarboxy-(3-hydroxy-3-methyl)-butyloxy]-coumarin + H2O
?
show the reaction diagram
-
-
-
-
?
acetanilide + H2O
acetate + aniline
show the reaction diagram
-
-
-
-
?
acetylsalicylic acid + H2O
salicylic acid + acetate
show the reaction diagram
B5THG6, -
-
-
-
?
acetylsalicylic acid + H2O
salicylic acid + acetate
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 0.94
-
-
?
alpha-cypermethrin + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-, Q9LAB8
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-, O76177
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
B3SST1 and B3SST2, -
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
O76177 and Q95UJ4
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
high activity
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
preferred substrate for the enzyme from the malathion-suceptible strain
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
enzyme activity increases from acetate to propionate to butanoate substrate
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
Emericella nidulans PW1
-
-
-
-
?
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl butanoate + H2O
alpha-naphthol + butanoate
show the reaction diagram
-
enzyme activity increases from acetate to propionate to butanoate substrate
-
-
?
alpha-naphthyl butyrate + H2O
alpha-naphthol + butyrate
show the reaction diagram
-
-
-
?
alpha-naphthyl butyrate + H2O
alpha-naphthol + butyrate
show the reaction diagram
-
-
-
-
?
alpha-naphthyl butyrate + H2O
alpha-naphthol + butyrate
show the reaction diagram
-, O76177
-
-
-
?
alpha-naphthyl butyrate + H2O
alpha-naphthol + butyrate
show the reaction diagram
O76177 and Q95UJ4
-
-
-
?
alpha-naphthyl caprate + H2O
alpha-naphthol + caprate
show the reaction diagram
-
-
-
?
alpha-naphthyl caproate + H2O
alpha-naphthol + caproate
show the reaction diagram
-
-
-
?
alpha-naphthyl caprylate + H2O
alpha-naphthol + caprylate
show the reaction diagram
-
-
-
?
alpha-naphthyl caprylate + H2O
alpha-naphthol + caprylate
show the reaction diagram
-, O76177
-
-
-
?
alpha-naphthyl nonanoate + H2O
alpha-naphthol + nonanoate
show the reaction diagram
-, Q9LAB8
low activity
-
?
alpha-naphthyl propionate + H2O
alpha-naphthol + propionate
show the reaction diagram
-, O76177
-
-
-
?
alpha-naphthyl propionate + H2O
alpha-naphthol + propionate
show the reaction diagram
-
enzyme activity increases from acetate to propionate to butanoate substrate
-
-
?
alpha/beta-naphthyl butyrate + H2O
alpha/beta-naphthol + butyrate
show the reaction diagram
-, Q9LAB8
-
-
?
alpha/beta-naphthyl propionate + H2O
alpha/beta-naphthol + propionate
show the reaction diagram
-, Q9LAB8
best substrate
-
?
alpha/beta-naphthyl valerate + H2O
alpha/beta-naphthol + valerate
show the reaction diagram
-, Q9LAB8
-
-
?
ampicillin + H2O
?
show the reaction diagram
-
-
-
-
?
anisamidobutyric acid + H2O
?
show the reaction diagram
-
-
-
-
?
aspirin + H2O
acetate + salicylate
show the reaction diagram
-
-
-
-
?
aspirin + H2O
acetate + salicylate
show the reaction diagram
-
-
-
-
?
aspirin + H2O
acetate + salicylate
show the reaction diagram
-
no activity
-
-
-
benazepril + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Gly-farnesyl-L-cysteine methyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
benzyl (trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate) + H2O
benzol + trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate
show the reaction diagram
-
i.e. benzyl cetraxate
-
?
benzyl acetate + H2O
benzene + acetate
show the reaction diagram
-
-
-
-
?
benzyl propionate + H2O
benzene + propionate
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-D-Tyr-p-nitrophenyl ester + H2O
benzyloxycarbonyl-D-Tyr + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-D-Tyr-p-nitrophenyl ester + H2O
benzyloxycarbonyl-D-Tyr + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Gly-p-nitrophenyl ester + H2O
benzyloxycarbonyl-Gly + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-L-Ala-p-nitrophenyl ester + H2O
benzyloxycarbonyl-L-Ala + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-L-Tyr-p-nitrophenyl ester + H2O
benzyloxycarbonyl-L-Tyr + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-L-Tyr-p-nitrophenyl ester + H2O
benzyloxycarbonyl-L-Tyr + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-L-Tyr-p-nitrophenyl ester + H2O
benzyloxycarbonyl-L-Tyr + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
beta-naphthyl acetate + H2O
beta-naphthol + acetate
show the reaction diagram
-
-
-
-
?
beta-naphthyl acetate + H2O
beta-naphthol + acetate
show the reaction diagram
Culex sp.
-
-
-
-
?
beta-naphthyl acetate + H2O
beta-naphthol + acetate
show the reaction diagram
-, O76177
-
-
-
?
beta-naphthyl acetate + H2O
beta-naphthol + acetate
show the reaction diagram
O76177 and Q95UJ4
-
-
-
?
beta-naphthyl acetate + H2O
beta-naphthol + acetate
show the reaction diagram
-
-
-
-
?
beta-naphthyl caproate + H2O
beta-naphthol + caproate
show the reaction diagram
-, Q9LAB8
low activity
-
?
beta-phenethyl acetate + H2O
?
show the reaction diagram
-
-
-
-
?
beta-thionaphthyl acetate + H2O
beta-thionaphthol + acetate
show the reaction diagram
-
-
-
-
?
betamethasone valerate + H2O
betamethasone + valerate
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 0.21
-
-
?
bioresmethrin + H2O
?
show the reaction diagram
-
-
-
-
-
bioresmethrin + H2O
?
show the reaction diagram
O70177
-
-
-
?
bioresmethrin + H2O
?
show the reaction diagram
-
-
-
-
-
bis(2-ethylhexyl)phthalate + H2O
?
show the reaction diagram
-
-
-
-
?
bisphenyl carbonate + H2O
?
show the reaction diagram
-
-
-
-
?
butanilcain + H2O
?
show the reaction diagram
-
-
-
-
?
butyl 2-(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenoxy)propanoate + H2O
2-(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenoxy)propanoic acid + butanol
show the reaction diagram
Q6H8W7
i.e. fluazifop butyl
-
-
?
butyl acetate + H2O
butanol + acetate
show the reaction diagram
-, Q8KT44
-
-
?
butyl acetate + H2O
butanol + acetate
show the reaction diagram
-
-
-
-
?
butyl acetate + H2O
butanol + acetate
show the reaction diagram
O28511
the enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
butyl benzoate + H2O
benzoate + butanol
show the reaction diagram
-
at 5-6% of the rate of monobutyl phthalate
-
-
?
butyl octanoate + H2O
butanol + octanoate
show the reaction diagram
-, Q8GR22
-
-
?
butyl paraben + H2O
butanol + 4-hydroxybenzoate
show the reaction diagram
-
-
-
?
butyrylthiocholine + H2O
butyric acid + thiocholine
show the reaction diagram
-
-
-
-
?
butyrylthiocholine + H2O
butyric acid + thiocholine
show the reaction diagram
-
activity of serum enzyme, no activity of liver enzyme
-
-
?
camostat mesilate + H2O
?
show the reaction diagram
-
-
-
-
?
capric acid + sn-glycerol
1-monocaprin
show the reaction diagram
-
the carboxylesterase performs also the esterification reaction using capric acid and glycerol as substrates resulting in formation of 1-monocaprin, product analysis by HPLC and method optimization, overview
-
-
?
capsaicin + H2O
?
show the reaction diagram
-
-
-
-
?
carboxyfluorescein diacetate + H2O
carboxyfluorescein + acetate
show the reaction diagram
-
-
-
-
?
carboxyfluorescein diacetate + H2O
?
show the reaction diagram
-
-
-
-
?
cefazolin + H2O
?
show the reaction diagram
-
-
-
-
?
cephaloridine + H2O
?
show the reaction diagram
-
-
-
-
?
cephalothin + H2O
?
show the reaction diagram
-
-
-
-
?
chlorpyrifos + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
cholesterol ester + H2O
?
show the reaction diagram
-
-
-
-
?
cholesterol oleate + H2O
cholesterol + oleate
show the reaction diagram
-
-
-
-
?
cholesterol oleate + H2O
cholesterol + oleate
show the reaction diagram
-
-
-
-
-
cholesteryl oleate + H2O
cholesterol + oleate
show the reaction diagram
-
-
-
-
?
cis-cypermethrin + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
cis-permethrin + H2O
?
show the reaction diagram
-, Q52NW7
-
-
-
?
cis-permethrin + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
clodinafop-propargyl + H2O
? + prop-2-yn-1-ol
show the reaction diagram
-
-
-
-
?
clopidogrel + H2O
(2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid + methanol
show the reaction diagram
-
-
-
-
?
clopidogrel + H2O
(2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid + methanol
show the reaction diagram
-
an anti-thrombogenic agent
-
-
?
cocaine + H2O
ecgonine methyl ester + benzoate
show the reaction diagram
-
specific substrate for isozyme CES1
-
-
?
cocaine + H2O
ecgonine methyl ester + benzoate
show the reaction diagram
-
the substrate is more specific for isozyme CES2 than for CES1
-
-
?
cocaine + H2O
O-benzoylecgonine + methanol
show the reaction diagram
-
-
-
-
?
cocaine + H2O
O-benzoylecgonine + methanol
show the reaction diagram
-
-
-
-
?
cocaine + H2O
O-benzoylecgonine + methanol
show the reaction diagram
-
the enzyme is site- and stereospecific for hydrolysis and transesterification of the methyl ester linkage on R-cocaine
-
-
?
cocaine + H2O
O-benzoylecgonine + methanol
show the reaction diagram
Geobacillus stearothermophilus CICC 20156
-
-
-
-
?
CPT-11 + H2O
SN-38 + ?
show the reaction diagram
-
the substrate is more specific for isozyme CES2 than for CES1
-
-
?
CPT-11 + H2O
SN-38 + 1,4'-bipiperidine-1'-carboxylic acid + CO2
show the reaction diagram
-
-
-
-
?
CPT-11 + H2O
SN-38 + 1,4'-bipiperidine-1'-carboxylic acid + CO2
show the reaction diagram
-
-
-
-
?
CPT-11 + H2O
SN-38 + 1,4'-bipiperidine-1'-carboxylic acid + CO2
show the reaction diagram
-
CPT-11 is also named irinotecan, i.e. 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin. Human intestine carboxylesterase demonstrates the most efficient kinetic parameters for CPT-11 hydrolysis to the active metabolite SN-38
-
-
?
CPT-11 + H2O
SN-38 + 1,4'-bipiperidine-1'-carboxylic acid + CO2
show the reaction diagram
-
other name irinotecan
-
-
?
cyano(3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
hydroxy(3-phenoxyphenyl)acetonitrile + 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
cyano(6-methoxy-2-naphthyl)methyl 2,2,3,3-tetramethylcyclopropanecarboxylate + H2O
hydroxy(6-methoxy-2-naphthyl)acetonitrile + 2,2,3,3-tetramethylcyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
cyano(6-methoxy-2-naphthyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
hydroxy(6-methoxy-2-naphthyl)acetonitrile + 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-, Q8BK48
-
-
-
?
cyano(6-methoxy-2-naphthyl)methyl butanoate + H2O
hydroxy(6-methoxy-2-naphthyl)acetonitrile + butanoate
show the reaction diagram
-, Q8BK48
-
-
-
?
cyano(6-methoxynaphthalen-2-yl)methyl (2S)-2-(4-chlorophenyl)-3-methylbutanoic acid + H2O
(2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + hydroxy(6-methoxy-2-naphthyl)acetonitrile
show the reaction diagram
-, Q8BK48
-
-
-
?
cyano(6-methoxynaphthalen-2-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylic acid + H2O
hydroxy(6-methoxy-2-naphthyl)acetonitrile + 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylic acid
show the reaction diagram
P23141
-
-
-
?
cyclic poly(ethylene terephthalate) trimer + H2O
?
show the reaction diagram
Thermobifida fusca, Thermobifida fusca KW3
-
-
-
-
?
cypermethrin + H2O
?
show the reaction diagram
-, Q52NW7
-
-
-
?
cypermethrin + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
D-glucose pentaacetate + H2O
? + acetate
show the reaction diagram
-
-
-
-
?
D-methyl phenidate + H2O
?
show the reaction diagram
-
-
-
-
?
D-methylphenidate + H2O
methanol + phenyl(piperidin-2-yl)acetate
show the reaction diagram
-
-
-
-
?
D-Tyr ethyl ester + H2O
D-Tyr + ethanol
show the reaction diagram
-
-
-
-
?
D-xylose tetraacetate + H2O
? + acetate
show the reaction diagram
-
-
-
-
?
delapril + H2O
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)glycine + ethanol
show the reaction diagram
-
-
-
-
?
deltamethrin + H2O
?
show the reaction diagram
-
-
-
-
?
deltamethrin + H2O
?
show the reaction diagram
-, Q52NW7
-
-
-
?
derapril + H2O
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)glycine + ethanol
show the reaction diagram
-
-
-
-
?
dicaprin + H2O
?
show the reaction diagram
-
-
-
-
?
diethyl (6-methoxynaphthalen-2-yl)(methyl)propanedioate + H2O
ethanol + (2S)-3-ethoxy-2-(6-methoxynaphthalen-2-yl)-2-methyl-3-oxopropanoic acid
show the reaction diagram
Sulfolobus tokodaii, Sulfolobus tokodaii 7
-
-
-
-
?
diethyl methyl(phenyl)propanedioate + H2O
ethanol + (2S)-3-ethoxy-2-methyl-3-oxo-2-phenylpropanoic acid
show the reaction diagram
Sulfolobus tokodaii, Sulfolobus tokodaii 7
-
-
-
-
?
diethyl succinate + H2O
?
show the reaction diagram
-
-
-
-
-
diltiazem + H2O
?
show the reaction diagram
-
-
-
-
?
dimethyl cis-cyclohex-4-ene-1,2-dicarboxylate + H2O
methyl hydrogen (1S,2R)-cyclohex-4-ene-1,2-dicarboxylate + methanol
show the reaction diagram
-
enantioselectivity, 98% at 25C, 96% at 50C
94-97% of the R-enantiomer
ir
diolein + H2O
?
show the reaction diagram
Emericella nidulans, Emericella nidulans PW1
-
-
-
-
?
DL-methyl 2-chloropropionate + H2O
?
show the reaction diagram
-, Q3HWU8
25% of the activity with methyl DL-beta-acetylthioisobutyrate
-
-
?
DL-methyl 2-chloropropionate + H2O
?
show the reaction diagram
-, Q3HWU8
as active as with methyl DL-beta-acetylthioisobutyrate
-
-
?
DL-methyl 2-chloropropionate + H2O
?
show the reaction diagram
Pseudomonas putida IFO12996
Q3HWU8
25% of the activity with methyl DL-beta-acetylthioisobutyrate, as active as with methyl DL-beta-acetylthioisobutyrate
-
-
?
DL-methylphenidate + H2O
methanol + phenyl(piperidin-2-yl)acetate
show the reaction diagram
-
-
-
-
?
epsilon-caprolacone + H2O
hexanoate
show the reaction diagram
-
the enzyme catalyzes a ring-opening polymerization of epsilon-caprolactone
-
-
?
epsilon-cypermethrin + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
estrone acetate + H2O
estrone + acetate
show the reaction diagram
-
-
-
-
?
ethanol + acetate
ethyl acetate + H2O
show the reaction diagram
Q89528, Q8KWI9
ester formation
-
?
ethanol + acetate
ethyl acetate
show the reaction diagram
-
esterification reaction
-
?
ethanol + acetyl-CoA
ethyl acetate + CoA + H2O
show the reaction diagram
Q89528, Q8KWI9
ester formation
-
?
ethanol + butyrate
ethyl butanoate + H2O
show the reaction diagram
Q89528, Q8KWI9
ester formation
-
?
ethyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate + H2O
ethanol + (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
show the reaction diagram
Sulfolobus tokodaii, Sulfolobus tokodaii 7
-
-
-
-
?
ethyl (2S)-2-phenylpropanoate + H2O
ethanol + (2S)-2-phenylpropanoate
show the reaction diagram
Sulfolobus tokodaii, Sulfolobus tokodaii 7
-
-
-
-
?
ethyl (trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate) + H2O
ethanol + trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate
show the reaction diagram
Microbacterium sp., Microbacterium sp. 7-1W
-
i.e. ethyl cetraxate
-
?
ethyl 2-(4-((6-chloro-1,3-benzothiazol-2-yl)oxy)phenoxy)propanoate + H2O
2-(4-((6-chloro-1,3-benzothiazol-2-yl)oxy)phenoxy)propanoic acid + ethanol
show the reaction diagram
Q6H8W7
i.e. fenthiaprop ethyl
-
-
?
ethyl 2-(4-((6-chloro-1,3-benzoxazol-2-yl)oxy)phenoxy)propanoate + H2O
2-(4-((6-chloro-1,3-benzoxazol-2-yl)oxy)phenoxy)propanoic acid + ethanol
show the reaction diagram
Q6H8W7
i.e. fenoxaprop ethyl
-
-
?
ethyl 2-hydroxy-4-phenylbutanoate + H2O
2-hydroxy-4-phenylbutanoate + ethanol
show the reaction diagram
Q4PNS3
-
enantiopreference for (S)-isomer with enantiomeric excess of 80%
-
?
ethyl 3,4-dihydroxybenzoate + H2O
ethanol + 3,4-dihydroxybenzoate
show the reaction diagram
-
low activity
-
?
ethyl 3-hydroxybenzoate + H2O
ethanol + 3-hydroxybenzoate
show the reaction diagram
-
-
-
?
ethyl 3-methoxybenzoate + H2O
ethanol + 3-methoxybenzoate
show the reaction diagram
-
-
-
?
ethyl 4-hydroxybenzoate + H2O
ethanol + 4-hydroxybenzoate
show the reaction diagram
-
-
-
?
ethyl 4-methoxybenzoate + H2O
ethanol + 4-methoxybenzoate
show the reaction diagram
-
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
-
-
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
-
-
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
-
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
-, Q8KT44
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
B5THG6, -
-
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
-
-
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
Bacillus subtilis SR22
-
-
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
Lactobacillus casei LILA EstC
Q8KT44
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
Microbacterium sp. 7-1W
-
-
-
?
ethyl benzoate + H2O
ethanol + benzoate
show the reaction diagram
-
-
-
?
ethyl bromoacetate + H2O
ethanol + bromoacetate
show the reaction diagram
-
-
-
-
?
ethyl butanoate + H2O
ethanol + butanoate
show the reaction diagram
-
-
-
?
ethyl butanoate + H2O
ethanol + butanoate
show the reaction diagram
Q8KT44
-
-
?
ethyl butanoate + H2O
butanoate + ethanol
show the reaction diagram
-
-
-
-
?
ethyl butyrate + H2O
ethanol + butyrate
show the reaction diagram
-
-
-
-
?
ethyl butyrate + H2O
ethanol + butyrate
show the reaction diagram
-
-
-
-
?
ethyl butyrate + H2O
ethanol + butyrate
show the reaction diagram
-
-
-
-
-
ethyl butyrate + H2O
ethanol + butyrate
show the reaction diagram
-
-
-
-
?
ethyl butyrate + H2O
ethanol + butyrate
show the reaction diagram
-
-
-
-
?
ethyl butyrate + H2O
ethanol + butyrate
show the reaction diagram
-
-
-
-
?
ethyl butyrate + H2O
ethanol + butanoate
show the reaction diagram
-
-
-
?
ethyl butyrate + H2O
ethanol + butanoate
show the reaction diagram
O28511
the enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
ethyl caproate + H2O
ethanol + caproate
show the reaction diagram
-
-
-
?
ethyl caprylate + H2O
ethanol + caprylate
show the reaction diagram
-
-
-
-
?
ethyl chloroacetate + H2O
ethanol + chloroacetate
show the reaction diagram
-
-
-
-
?
ethyl D-pantothenate + H2O
ethanol + D-pantothenate
show the reaction diagram
-
-
-
?
ethyl DL-beta-acetylthioisobutyrate + H2O
?
show the reaction diagram
-, Q3HWU8
40% of the activity with methyl DL-beta-acetylthioisobutyrate
-
-
?
ethyl DL-beta-acetylthioisobutyrate + H2O
?
show the reaction diagram
Pseudomonas putida IFO12996
Q3HWU8
40% of the activity with methyl DL-beta-acetylthioisobutyrate
-
-
?
ethyl fluoroacetate + H2O
ethanol + fluoroacetate
show the reaction diagram
-
-
-
-
?
ethyl hexanoate + H2O
ethanol + hexanoate
show the reaction diagram
-
-
-
?
ethyl hexanoate + H2O
ethanol + hexanoate
show the reaction diagram
Q8KT44
-
-
?
ethyl hexanoate + H2O
ethanol + hexanoate
show the reaction diagram
-, Q8GR22
-
-
?
ethyl iodoacetate + H2O
ethanol + iodoacetate
show the reaction diagram
-
-
-
-
?
ethyl L-pantothenate + H2O
ethanol + L-pantothenate
show the reaction diagram
-
-
-
?
ethyl laurate + H2O
ethanol + laurate
show the reaction diagram
-, Q8GR22
-
-
?
ethyl myristate + H2O
ethanol + myristate
show the reaction diagram
-, Q8GR22
-
-
?
ethyl octanoate + H2O
ethanol + octanoate
show the reaction diagram
-, Q8GR22
-
-
?
ethyl paraben + H2O
ethanol + 4-hydroxybenzoate
show the reaction diagram
Enterobacter cloacae, Enterobacter cloacae EM
-
best substrate
-
?
ethyl pelargonate + H2O
ethanol + pelargonate
show the reaction diagram
-, Q8GR22
-
-
?
ethyl pentanoate + H2O
ethanol + pentanoate
show the reaction diagram
-
-
-
?
ethyl pentanoate + H2O
ethanol + pentanoate
show the reaction diagram
Q8KT44
-
-
?
ethyl propionate + H2O
ethanol + propionate
show the reaction diagram
-
-
-
-
?
ethyl propionate + H2O
ethanol + propionate
show the reaction diagram
-
-
-
-
?
ethyl propionate + H2O
ethanol + propionate
show the reaction diagram
-, Q8KT44
-
-
?
ethyl propionate + H2O
ethanol + propionate
show the reaction diagram
-
-
-
-
?
ethyl propionate + H2O
ethanol + propionate
show the reaction diagram
O28511
the enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
ethyl thiolacetate + H2O
ethanol + ethanethioic S-acid
show the reaction diagram
-
-
-
-
?
ethyl valerate + H2O
ethanol + valerate
show the reaction diagram
-
-
-
?
ethyl valerate + H2O
ethanol + valeric acid
show the reaction diagram
Q7M529, -
-
-
-
?
ethylene glycol dibenzoate + H2O
?
show the reaction diagram
Aspergillus nomius, Aspergillus nomius HS-1
-
-
-
?
fenitrothion + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
fenvalerate + H2O
?
show the reaction diagram
-, Q52NW7
-
-
-
?
fluorescein diacetate + H2O
?
show the reaction diagram
-
-
-
-
?
fluorescein diacetate + H2O
?
show the reaction diagram
-
specific probe substrate for isoform CES2
-
-
?
fluorescein diacetate + H2O
fluorescein + acetate
show the reaction diagram
-
-
-
-
?
glucose pentaacetate + H2O
?
show the reaction diagram
Arthrobacter viscosus, Arthrobacter viscosus NRRL B-1973
-
-
-
-
?
glyceryl tributyrate + H2O
?
show the reaction diagram
Q97VU2, -
-
-
-
?
glyceryl tributyrate + H2O
?
show the reaction diagram
-
-
-
-
?
glyceryl tributyrate + H2O
?
show the reaction diagram
Q97VU2, -
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl tributyrate + H2O
?
show the reaction diagram
Q97VU2
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl tridecanoate + H2O
?
show the reaction diagram
Q97VU2, -
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl tridecanoate + H2O
?
show the reaction diagram
Q97VU2
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl trihexanoate + H2O
?
show the reaction diagram
Q97VU2, -
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl trioctanoate + H2O
?
show the reaction diagram
Q97VU2, -
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl trioleate + H2O
?
show the reaction diagram
Q97VU2, -
-
-
-
?
glyceryl trioleate + H2O
?
show the reaction diagram
-
-
-
-
?
glyceryl trioleate + H2O
?
show the reaction diagram
Q97VU2, -
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl trioleate + H2O
?
show the reaction diagram
Q97VU2
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
heroin + H2O
6-monoacetylmorphine + acetate
show the reaction diagram
-
the substrate is more specific for isozyme CES2 than for CES1
-
-
?
heroin + H2O
6-monoacetylmorphine + acetate
show the reaction diagram
-
hCE1 can metabolize the conversion of heroin to both 6-monoacetylmorphine and morphine. hCE1 is able to catalyze both reactions, but it is more efficient at the hydrolysis of heroin to 6-monoacetylmorphine, the first step of heroin metabolism
-
-
?
hexyl acetate + H2O
hexanol + acetate
show the reaction diagram
-, Q8KT44
-
-
?
hexyl valerate + H2O
hexanol + valeric acid
show the reaction diagram
Q7M529, -
-
-
-
?
hydrocinnamoyl farnesyl-L-cysteine methyl ester + H2O
N-(3-phenylpropanoyl)-S-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-L-cysteine + methanol
show the reaction diagram
-
-
-
-
?
hydroxyethylflurbiprofen + H2O
ethanol + flurbiprofen
show the reaction diagram
-
-
-
-
?
hydroxypropylflurbiprofen + H2O
propanol + flurbiprofen
show the reaction diagram
-
-
-
-
?
imidapril + H2O
?
show the reaction diagram
-
-
-
-
?
imidapril + H2O
?
show the reaction diagram
-
the substrate is more specific for isozyme CES2 than for CES1
-
-
?
imidapril + H2O
imidaprilat + ?
show the reaction diagram
-
-
-
-
?
indoxyl acetate + H2O
indol-3-ol + acetate
show the reaction diagram
-
-
-
-
?
irinotecan + H2O
?
show the reaction diagram
-
-
-
-
?
irinotecan + H2O
?
show the reaction diagram
-
other name CPT-11
-
-
?
irinotecan + H2O
7-ethyl-10-hydroxycampothecin + 1,4'-bipiperidine-1'-carboxylic acid
show the reaction diagram
-
antitumor prodrug, poor substrate
-
-
?
irinotecan + H2O
7-ethyl-10-hydroxycampothecin + 1,4'-bipiperidine-1'-carboxylic acid
show the reaction diagram
P12337
antitumor prodrug, poor substrate
-
-
?
irinotecan-7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin + H2O
?
show the reaction diagram
-
i.e. CPT-11, an anti-tumor agent
-
-
?
irinotecan-7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin + H2O
?
show the reaction diagram
-
i.e. CPT-11
-
-
?
isopentyl octanoate + H2O
isopentanol + octanoate
show the reaction diagram
-, Q8GR22
-
-
?
isopropyl (trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate) + H2O
isopropanol + trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate
show the reaction diagram
Microbacterium sp., Microbacterium sp. 7-1W
-
i.e. propyl cetraxate
-
?
isopropyl acetate + H2O
isopropanol + acetate
show the reaction diagram
-
-
-
-
?
isopropyl octanoate + H2O
isopropanol + octanoate
show the reaction diagram
-, Q8GR22
-
-
?
ispopropenyl acetate + H2O
isopropenol + acetate
show the reaction diagram
-
-
-
-
?
ketoprofen ethyl ester + H2O
R-ketoprofen + ethanol
show the reaction diagram
-
-
R-isomer is main product of keratinocyte enzyme
-
?
ketoprofen ethyl ester + H2O
ketoprofen + ethanol
show the reaction diagram
-
-
-
-
?
L-methyl phenidate + H2O
?
show the reaction diagram
-
-
-
-
?
L-phenylalanine butyl ester + H2O
L-phenylalanine + butanol
show the reaction diagram
-
-
-
-
?
L-phenylalanine ethyl ester + H2O
L-phenylalanine + ethanol
show the reaction diagram
-
-
-
-
?
L-Tyr ethyl ester + H2O
L-Tyr + ethanol
show the reaction diagram
-
-
-
-
?
L-Tyr ethyl ester + H2O
L-Tyr + ethanol
show the reaction diagram
-
-
-
-
?
linalyl acetate + H2O
linalool + acetate
show the reaction diagram
-, P37967
-
-
-
?
linalyl acetate + H2O
linalool + acetate
show the reaction diagram
-
model substrate for study of enantioselectivity in the enzyme reaction, low enantioselectivity, overview
-
?
linalyl acetate + H2O
linalool + acetate
show the reaction diagram
-
model substrate for study of enantioselectivity in the enzyme reaction, overview
-
?
malathion + H2O
?
show the reaction diagram
-
-
-
?
malathion + H2O
?
show the reaction diagram
-, Q52NW7
-
-
-
?
malathion + H2O
?
show the reaction diagram
Culex sp.
-
-
-
-
?
malathion + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
malathion + H2O
?
show the reaction diagram
-
preferred substrate for the malathion esterase from the malathion-resistant strain
-
?
malathion + H2O
?
show the reaction diagram
Q52NW7
-
-
-
?
malathion + H2O
malathion alpha-monocarboxylic acid + malathion beta-monocarboxylic acid
show the reaction diagram
-
-
-
-
?
meperidine + H2O
?
show the reaction diagram
-
specific substrate for isozyme CES1
-
-
?
methanethiol + acetyl-CoA
methanethioacetate + coenzyme A
show the reaction diagram
Q89528, Q8KWI9
ester formation
-
?
methyl (-)-2-(3-benzoylphenyl)propionate + H2O
(-)-2-(3-benzoylphenyl)propionate + methanol
show the reaction diagram
Q97VW1
-
-
-
?
methyl (trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate) + H2O
methanol + trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate
show the reaction diagram
Microbacterium sp., Microbacterium sp. 7-1W
-
i.e. methyl cetraxate
-
?
methyl 1H-indole-3-carboxylate + H2O
methanol + 1H-indole-3-carboxylate
show the reaction diagram
Q9SG92
-
-
-
-
methyl 2-(4-(2,4-dichlorophenoxy)phenoxy)propanoate + H2O
2-(4-(2,4-dichlorophenoxy)phenoxy)propanoic acid + methanol
show the reaction diagram
Q6H8W7
i.e. Diclofop methyl
-
-
?
methyl 2-aminobenzoate + H2O
methanol + 2-aminobenzoate
show the reaction diagram
-
-
-
?
methyl 2-hydroxybenzoate + H2O
methanol + 2-hydroxybenzoate
show the reaction diagram
-
very low activity
-
?
methyl 3,5-dihydroxybenzoate + H2O
methanol + 3-hydroxybenzoate
show the reaction diagram
-
low activity
-
?
methyl 3-(4-hydroxyphenyl)propionate + H2O
methanol + 3-(4-hydroxyphenyl)propionate
show the reaction diagram
-
-
-
?
methyl 3-hydroxybenzoate + H2O
methanol + 3-hydroxybenzoate
show the reaction diagram
-
-
-
?
methyl 4-aminobenzoate + H2O
methanol + 4-aminobenzoate
show the reaction diagram
-
-
-
?
methyl 4-nitrobenzoate + H2O
4-nitrobenzoate + methanol
show the reaction diagram
-
specific substrate for isoform ES1
-
-
?
methyl acetate
methanol + acetate
show the reaction diagram
-
poor substrate
-
-
?
methyl acetate + H2O
methanol + acetate
show the reaction diagram
-
-
-
-
?
methyl acetate + H2O
methanol + acetate
show the reaction diagram
-
-
-
-
?
methyl acetate + H2O
methanol + acetate
show the reaction diagram
O28511
the enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
methyl benzoate + H2O
methanol + benzoate
show the reaction diagram
-
low activity
-
?
methyl butanoate + H2O
methanol + butanoate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butanoate
show the reaction diagram
O28511
preferred substrate. The enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
-
-
-
-
?
methyl caprate + H2O
methanol + decanoate
show the reaction diagram
-
-
-
-
?
methyl D-pantothenate + H2O
methanol + D-pantothenate
show the reaction diagram
-
-
-
?
methyl DL-beta-acetylthioisobutyrate + H2O
D-beta-acetylthioisobutyrate + methanol
show the reaction diagram
-, Q3HWU8
produces D-beta-acetylthioisobutyrate with a degree of conversion of 49.5% and an enantiomeric excess value of 97.2% at an optimum pH of about 8-10 and an optimum temperature of about 57 to 67C
-
-
?
methyl DL-beta-acetylthioisobutyrate + H2O
D-beta-acetylthioisobutyrate + methanol
show the reaction diagram
Pseudomonas putida IFO12996
Q3HWU8
produces D-beta-acetylthioisobutyrate with a degree of conversion of 49.5% and an enantiomeric excess value of 97.2% at an optimum pH of about 8-10 and an optimum temperature of about 57 to 67C
-
-
?
methyl hexanoate + H2O
methanol + hexanoate
show the reaction diagram
-
-
-
-
?
methyl hexanoate + H2O
methanol + hexanoate
show the reaction diagram
-
-
-
-
?
methyl hexanoate + H2O
methanol + hexanoate
show the reaction diagram
-
-
-
-
?
methyl hexanoate + H2O
methanol + hexanoate
show the reaction diagram
O28511
the enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
methyl L-pantothenate + H2O
methanol + L-pantothenate
show the reaction diagram
-
-
-
?
methyl octanoate + H2O
methanol + octanoate
show the reaction diagram
-
-
-
-
?
methyl octanoate + H2O
methanol + octanoate
show the reaction diagram
-
-
-
-
?
methyl octanoate + H2O
methanol + octanoate
show the reaction diagram
-, Q8GR22
-
-
?
methyl paraben + H2O
methanol + 4-hydroxybenzoate
show the reaction diagram
Enterobacter cloacae, Enterobacter cloacae EM
-
-
-
?
methyl propionate + H2O
methanol + propionate
show the reaction diagram
-
-
-
-
?
methyl propionate + H2O
methanol + propionate
show the reaction diagram
-
no activity
-
-
-
methyl propionate + H2O
methanol + propionate
show the reaction diagram
-
hydrolyzed at highest rate among the fatty acid methyl esters
-
-
?
methyl propionate + H2O
methanol + propionate
show the reaction diagram
O28511
the enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
methyl propionate + H2O
methanol + propionate
show the reaction diagram
-
hydrolyzed at highest rate among the fatty acid methyl esters
-
-
?
methyl salicylate + H2O
salicylic acid + methanol
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 15.3
-
-
?
methyl salicylate + H2O
methanol + salicylate
show the reaction diagram
-
-
-
-
?
methyl vanillate + H2O
methanol + vanillate
show the reaction diagram
-
-
-
?
methyl-2,4-dichlorophenoxyacetate + H2O
2,4-dichlorophenoxyacetic acid + methanol
show the reaction diagram
-
i.e. 2,4-D-methyl
activation of pro-herbicide to phytotoxic acid. Isoform CXE12 is the major carboxyesterase responsible for activation
-
?
methylphenidate + H2O
?
show the reaction diagram
-
specific substrate for isozyme CES1
-
-
?
methylprednisolone 21-hemisuccinate + H2O
?
show the reaction diagram
-
the substrate is more specific for isozyme CES2 than for CES1
-
-
?
methylumbelliferyl acetate + H2o
methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
monobutyl phthalate + H2O
phthalate + butanol
show the reaction diagram
-
-
-
-
?
monocaprin + H2O
glycerol + caproate
show the reaction diagram
-
-
-
-
?
monoelaidin + H2O
elaidic acid + glycerol
show the reaction diagram
-
-
-
-
-
monoolein + H2O
glycerol + oleic acid
show the reaction diagram
Emericella nidulans, Emericella nidulans PW1
-
-
-
-
?
monopalmitoin + H2O
glycerol + palmitoleic acid
show the reaction diagram
-
-
-
-
?
monopentyl phthalate + H2O
phthalate + pentanol
show the reaction diagram
-
at 50% of the rate of monobutyl phthalate
-
-
?
mycophenolate mofetil + H2O
mycophenolic acid + mofetil
show the reaction diagram
-
prodrug, activation
-
-
?
N-acetyl L-phenylalanine ethyl ester + H2O
N-acetyl L-phenylalanine + ethanol
show the reaction diagram
-
-
-
-
?
N-acetyl-L-Ala-1-naphthyl ester + H2O
N-acetyl-L-Ala + 1-naphthol
show the reaction diagram
-
-
-
-
?
N-acetyl-L-phenylalanine methyl ester + H2O
N-acetyl-L-phenylalanine + methanol
show the reaction diagram
-
-
-
-
?
n-butyl acetate + H2O
n-butanol + acetate
show the reaction diagram
-
-
-
-
?
n-butyl benzoate + H2O
n-butanol + benzoate
show the reaction diagram
-
-
-
?
n-butyl n-butyrate + H2O
n-butanol + n-butyrate
show the reaction diagram
-
-
-
-
?
n-butyl n-butyrate + H2O
n-butanol + n-butyrate
show the reaction diagram
-
-
-
-
?
n-butyryl salicylate + H2O
n-butanol + salicylate
show the reaction diagram
-
-
-
-
?
n-decanoyl salicylate + H2O
? + salicylate
show the reaction diagram
-
-
-
-
?
N-ethylglycine xylidide + H2O
?
show the reaction diagram
-
-
-
-
?
n-heptyl acetate + H2O
n-heptanol + acetate
show the reaction diagram
-
-
-
-
?
n-hexanoyl salicylate + H2O
n-hexanol + salicylate
show the reaction diagram
-
-
-
-
?
n-hexyl acetate + H2O
n-hexanol + acetate
show the reaction diagram
Bacillus subtilis, Bacillus subtilis SR22
-
-
-
-
?
n-octanoyl salicylate + H2O
? + salicylate
show the reaction diagram
-
-
-
-
?
n-octyl acetate + H2O
n-octanol + acetate
show the reaction diagram
-
-
-
-
?
n-pentyl acetate + H2O
n-pentanol + acetate
show the reaction diagram
-
-
-
-
?
N-propyl acetate + H2O
n-propanol + acetate
show the reaction diagram
-
-
-
-
?
n-propyl D-pantothenate + H2O
n-propanol + D-pantothenate
show the reaction diagram
-
-
-
?
n-propyl L-pantothenate + H2O
n-propanol + L-pantothenate
show the reaction diagram
-
best substrate
-
?
n-propyl salicylate + H2O
n-propanol + salicylate
show the reaction diagram
-
-
-
-
?
n-valeryl salicylate + H2O
n-pentanol + salicylate
show the reaction diagram
-
-
-
-
?
naphthyl acetate + H2O
naphthol + acetate
show the reaction diagram
-
-
-
-
?
naphthyl acetate + H2O
naphthol + acetate
show the reaction diagram
-
-
-
-
?
naphthyl acetate + H2O
naphthol + acetate
show the reaction diagram
Q6H8W7
-
-
-
?
naphthyl acetate + H2O
naphthol + acetate
show the reaction diagram
Arthrobacter viscosus NRRL B-1973
-
-
-
-
?
nitrocefin + H2O
?
show the reaction diagram
-
i.e. 3-(2,4-dinitrosyl)-(6R,7R)-7-(2-thienylacetamido)-ceph-3-em-4-carboxylic acid
-
-
?
O-4-nitrophenyl acetate + H2O
O-4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
O-butyryl propranolol + H2O
butanoate + propranolol
show the reaction diagram
-
-
-
-
?
O-butyryl propranolol + H2O
butanoate + propranolol
show the reaction diagram
-
preferential hydrolysis of R-isomer by liver and intestine enzyme, non-enantioselective
-
-
?
O-butyryl propranolol + H2O
butanoate + propranolol
show the reaction diagram
-
preferential hydrolysis of R-isomer by liver enzyme
-
-
?
O-butyryl propranolol + H2O
butanoate + propranolol
show the reaction diagram
-
preferential hydrolysis of S-isomer by liver enzyme
-
-
?
oleoyl-CoA + H2O
oleic acid + CoA
show the reaction diagram
P23141
-
-
-
?
oleoyl-CoA + H2O
oleic acid + CoA
show the reaction diagram
-
-
-
-
?
oseltamivir + H2O
?
show the reaction diagram
-
-
-
-
?
oseltamivir + H2O
?
show the reaction diagram
-
-
-
-
?
oseltamivir + H2O
?
show the reaction diagram
-
specific substrate for isozyme CES1
-
-
?
oseltamivir + H2O
?
show the reaction diagram
-
an anti-viral drug
-
-
?
oxybutynin + H2O
?
show the reaction diagram
-
-
-
-
?
oxybutynin + H2O
2-cyclohexyl-2-phenylglycolic acid + ?
show the reaction diagram
-
-
-
-
?
p-nitrophenol butanoate + H2O
p-nitrophenol + butanoate
show the reaction diagram
-, P37967
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
-, P37967
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
P23141
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
-, P13001
-
-
-
-
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
Q6H8W7
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
-
hydrolysis proceeds in linear manner, 15% of the reaction rate with p-nitrophenyl butyrate
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
Escherichia coli DH5alpha
-
-
-
-
-
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
Sulfolobus shibatae DSM5389
-
hydrolysis proceeds in linear manner, 15% of the reaction rate with p-nitrophenyl butyrate
-
-
?
p-nitrophenyl butanoate + H2O
p-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl butanoate + H2O
p-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl butanoate + H2O
p-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl butyrate
p-nitrophenol + butyrate
show the reaction diagram
-, P13001
-
-
-
-
p-nitrophenyl butyrate
p-nitrophenol + butyrate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl butyrate
p-nitrophenol + butyrate
show the reaction diagram
Escherichia coli DH5alpha
-
-
-
-
-
p-nitrophenyl butyrate + H2O
p-nitrophenol + butanoate
show the reaction diagram
P04335
-
-
-
-
p-nitrophenyl caprate
p-nitrophenol + caprate
show the reaction diagram
-, P13001
-
-
-
-
p-nitrophenyl caprate
p-nitrophenol + caprate
show the reaction diagram
Escherichia coli DH5alpha
-
-
-
-
-
p-nitrophenyl caproate
p-nitrophenol + caproate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl caproate
p-nitrophenol + caproate
show the reaction diagram
-, P13001
-
-
-
-
p-nitrophenyl caproate
p-nitrophenol + caproate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl caproate
p-nitrophenol + caproate
show the reaction diagram
Escherichia coli DH5alpha
-
-
-
-
-
p-nitrophenyl caproate + H2O
p-nitrophenol + caproate
show the reaction diagram
Sulfolobus solfataricus, Sulfolobus solfataricus P1
-
-
-
-
?
p-nitrophenyl caprylate + H2O
p-nitrophenol + caprylate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl decanoate
p-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
-
p-nitrophenyl decanoate
p-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl hexanoate + H2O
p-nitrophenol + hexanoate
show the reaction diagram
Q97VU2, -
-
-
-
?
p-nitrophenyl hexanoate + H2O
p-nitrophenol + hexanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl laurate
p-nitrophenol + laurate
show the reaction diagram
-, P13001
-
-
-
-
p-nitrophenyl laurate
p-nitrophenol + laurate
show the reaction diagram
Escherichia coli DH5alpha
-
-
-
-
-
p-nitrophenyl myristate + H2O
p-nitrophenol + myristate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl octanoate
p-nitrophenol + decanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl octanoate
p-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl palmitate
p-nitrophenol + palmitate
show the reaction diagram
O33407
-
-
-
?
p-nitrophenyl palmitate + H2O
p-nitrophenol + palmitate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl palmitate + H2O
p-nitrophenol + palmitate
show the reaction diagram
-, P13001
-
-
-
-
p-nitrophenyl palmitate + H2O
p-nitrophenol + palmitate
show the reaction diagram
-
50% of the activity with p-nitrophenyl decanoate
-
-
?
p-nitrophenyl pentanoate + H2O
p-nitrophenol + pentanoate
show the reaction diagram
-
and substrates with longer acyl chains, hydrolysis proceeds in biophasic manner
-
-
?
p-nitrophenyl propionate
p-nitrophenol + propionate
show the reaction diagram
-, P13001
-
-
-
-
p-nitrophenyl stearate
p-nitrophenol + stearate
show the reaction diagram
-, P13001
-
-
-
-
p-nitrophenyl stearate + H2O
p-nitrophenol + stearate
show the reaction diagram
-
50% of the activity with p-nitrophenyl decanoate
-
-
?
p-nitrophenyl valerate + H2O
p-nitrophenol + valeric acid
show the reaction diagram
-
-
-
-
?
p-nitrophenyl valerate + H2O
p-nitrophenol + valeric acid
show the reaction diagram
-
79% of the reaction rate with p-nitrophenyl butyrate
-
-
?
p-tolyl octanoate + H2O
p-toluol + octanoate
show the reaction diagram
-, Q8GR22
-
-
?
palmitin + H2O
?
show the reaction diagram
-
-
-
-
?
palmitoyl-CoA
CoA + palmitate
show the reaction diagram
-, P13001
-
-
-
-
palmitoyl-CoA + H2O
palmitic acid + CoA
show the reaction diagram
-
-
-
-
?
palmitoyl-CoA + H2O
palmitic acid + CoA
show the reaction diagram
P23141
weak
-
-
?
paraoxon + H2O
?
show the reaction diagram
-
-
-
-
?
paraoxon + H2O
?
show the reaction diagram
-
-
-
-
?
penicillin G + H2O
?
show the reaction diagram
-
-
-
-
?
pentyl acetate + H2O
pentanol + acetate
show the reaction diagram
Q7M529, -
-
-
-
?
pentyl octanoate + H2O
pentanol + octanoate
show the reaction diagram
-, Q8GR22
-
-
?
pentyl PABC-Doxazolidine + H2O
PABC-Doxazolidine + pentanol
show the reaction diagram
-
-
-
-
?
pentyl valerate + H2O
pentanol + valeric acid
show the reaction diagram
Q7M529, -
not hydrolysed in the absence of Triton X-100
-
-
?
permethrin + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
permethrin + H2O
?
show the reaction diagram
-
the cis-form of permethrin is favorably hydrolyzed by isozyme HCE2, whereas the trans-form is comparably hydrolyzed by HCE1 and HCE2
-
-
?
phenolphthalein dibutyrate + H2O
?
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
-
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
Q8KT44
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-, Q8GR22
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
O28511
the enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
Q8GR22
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
Bacillus subtilis SR22
-
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
Lactobacillus delbrueckii subsp. lactis MG1363 EstA
-
-
-
?
phenyl acetate + H2O
phenol + acetate
show the reaction diagram
Lactobacillus casei LILA EstC
Q8KT44
-
-
?
phenyl butyrate + H2O
phenol + butyrate
show the reaction diagram
-
-
-
-
?
phenyl butyrate + H2O
phenol + butyrate
show the reaction diagram
-
-
-
-
?
phenyl butyrate + H2O
phenol + butyrate
show the reaction diagram
-
-
-
-
?
phenyl butyrate + H2O
phenol + butyrate
show the reaction diagram
-
-
-
-
?
phenyl butyrate + H2O
phenol + butyrate
show the reaction diagram
-
-
-
-
?
phenyl butyrate + H2O
phenol + butyrate
show the reaction diagram
-
-
-
-
?
phenyl butyrate + H2O
phenol + butyrate
show the reaction diagram
-
-
-
-
?
phenyl formate + H2O
phenol + formate
show the reaction diagram
-
-
-
-
?
phenyl formate + H2O
phenol + formate
show the reaction diagram
-
-
-
-
?
phenyl pentanoate + H2O
phenol + pentanoate
show the reaction diagram
-
-
-
-
?
phenyl pentanoate + H2O
phenol + pentanoate
show the reaction diagram
-
-
-
-
?
phenyl pivalate + H2O
phenol + pivalate
show the reaction diagram
-
-
-
-
-
phenyl pivalate + H2O
phenol + pivalate
show the reaction diagram
-
-
-
-
?
phenyl valerate + H2O
valerate + phenol
show the reaction diagram
-
-
-
-
?
phenylthioacetate + H2O
?
show the reaction diagram
Lactobacillus delbrueckii subsp. lactis, Lactobacillus delbrueckii subsp. lactis MG1363 EstA
-
-
-
?
phenylthioacetate + H2O
thiophenol + acetate
show the reaction diagram
-
-
-
-
?
phenylthioacetate + H2O
phenol + CoA + acetate
show the reaction diagram
-, Q8KT44
-
-
?
phenylthiobutyrate + H2O
thiophenol + butyrate
show the reaction diagram
-
-
-
-
?
phenylthioisobutyrate + H2O
thiophenol + isobutyrate
show the reaction diagram
-
-
-
-
?
phenylthiopentanoate + H2O
thiophenol + pentanoate
show the reaction diagram
-
-
-
-
?
phenylthiopropionate + H2O
thiophenol + propionate
show the reaction diagram
-
-
-
-
?
pranlukast + H2O
?
show the reaction diagram
-
effectively hydrolyzed by carboxylesterase pI 6.2 but not by the pI 6.0 enzyme
-
-
?
procaine + H2O
?
show the reaction diagram
-
-
-
-
?
proline-beta-naphthylamide + H2O
?
show the reaction diagram
Sus scrofa, Sus scrofa PLE
-
-
-
?
prop-2-yn-1-yl 2-(4-((5-chloro-3-fluoropyridin-2-yl)oxy)phenoxy)propanoate + H2O
2-(4-((5-chloro-3-fluoropyridin-2-yl)oxy)phenoxy)propanoic acid + prop-2-yn-1-ol
show the reaction diagram
Q6H8W7
i.e. clodinafop propargyl
-
-
?
propoxur + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
propyl acetate + H2O
propanol + acetate
show the reaction diagram
-, Q8KT44
-
-
?
propyl paraben + H2O
propanol + 4-hydroxybenzoate
show the reaction diagram
Enterobacter cloacae, Enterobacter cloacae EM
-
-
-
?
Rac-ibuprofen methyl ester + H2O
Rac-ibuprofen + methanol
show the reaction diagram
-
-
-
-
?
resorufine-butyrate + H2O
?
show the reaction diagram
-, Q9LAB8
low activity
-
?
retinyl palmitate + H2O
retinol + palmitate
show the reaction diagram
-
-
-
-
?
retinyl palmitate + H2O
retinol + palmitate
show the reaction diagram
O35535, O70631, P16303, Q63108, Q64573, Q8K3R0
-
-
-
-
retinyl palmitate + H2O
retinol + palmitate
show the reaction diagram
O35535, O70631, P16303, Q63108, Q64573, Q8K3R0
-
-
?
S-methyl thiobutyrate + H2O
?
show the reaction diagram
-, O76177
-
-
-
?
S-methylthiobutanoate + H2O
methanol + butanoate
show the reaction diagram
Q97VU2, -
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
sarin + H2O
?
show the reaction diagram
-
CE1 exhibits a 5fold preference for the PS isomer of a sarin analog
-
-
?
stearoyl-CoA + H2O
stearic acid + CoA
show the reaction diagram
-
-
-
-
?
t-butyl acetate + H2O
t-butanol + acetate
show the reaction diagram
-, P37967
-
-
-
?
t-butyl-gamma-(t-butoxycarbonylamino)-butyrate + H2O
?
show the reaction diagram
-, P37967
-
effective removal of t-butyl protecting group in organic synthesis
-
?
temephos + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
temocapril + H2O
?
show the reaction diagram
-
-
-
-
?
temocapril + H2O
?
show the reaction diagram
P23141
weak
-
-
?
temocapril + H2O
?
show the reaction diagram
-
specific substrate for isozyme CES1
-
-
?
temocapril + H2O
(+)-[(2S,6R)-6-[[(S)-1-carboxyl-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)perhydro-1,4-thiazepin-4-yl]acetic acid + propanol
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 734
-
-
?
trandolapril + H2O
trandolaprilat + ?
show the reaction diagram
-
trandolapril is a CES1 selective substrate while CES2 exerts little to no catalytic activity towards this compound
-
-
?
trans-cypermethrin + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
trans-methyl cinnamate + H2O
methanol + cinnamate
show the reaction diagram
-
very low activity
-
?
trans-permethrin + H2O
?
show the reaction diagram
-
-
-
-
?
trans-permethrin + H2O
?
show the reaction diagram
O70177
-
-
-
?
trans-permethrin + H2O
?
show the reaction diagram
-
-
-
?
trans-permethrin + H2O
?
show the reaction diagram
-, Q52NW7
-
-
-
?
trans-permethrin + H2O
?
show the reaction diagram
-, Q8BK48
-
-
-
?
trans-permethrin + H2O
(1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
-
-
-
-
?
triacetin + H2O
?
show the reaction diagram
-
-
-
-
?
triacetin + H2O
?
show the reaction diagram
-
-
-
-
?
triacetin + H2O
?
show the reaction diagram
Q7M529, -
-
-
-
?
triacetin + H2O
acetic acid + glycerol
show the reaction diagram
-
-
-
-
?
triacetin + H2O
acetic acid + glycerol
show the reaction diagram
-
-
-
-
?
triacetin + H2O
acetic acid + glycerol
show the reaction diagram
-
-
-
-
?
triacetin + H2O
acetic acid + glycerol
show the reaction diagram
-
-
-
-
?
triacetin + H2O
acetic acid + glycerol
show the reaction diagram
-
-
-
-
?
triacetin + H2O
acetic acid + glycerol
show the reaction diagram
B5THG6, -
-
-
-
?
triacetin + H2O
acetic acid + glycerol
show the reaction diagram
Q4PNS3
about 65% of the activity with tributyrin
-
-
?
tributyrin + H2O
?
show the reaction diagram
-
-
-
-
?
tributyrin + H2O
?
show the reaction diagram
-
-
-
-
?
tributyrin + H2O
?
show the reaction diagram
-
-
-
-
?
tributyrin + H2O
?
show the reaction diagram
-
-
-
-
?
tributyrin + H2O
?
show the reaction diagram
-
-
-
?
tributyrin + H2O
?
show the reaction diagram
-, Q8GR22
-
-
?
tributyrin + H2O
?
show the reaction diagram
Q7M529, -
-
-
-
?
tributyrin + H2O
?
show the reaction diagram
G3JWZ2, -
-
-
-
?
tributyrin + H2O
?
show the reaction diagram
O73957
no activity with triolein, suggesting that this lipolytic enzyme is not a true lipase
-
-
?
tributyrin + H2O
?
show the reaction diagram
Geobacillus thermodenitrificans CMB-A2
G3JWZ2
-
-
-
?
tributyrin + H2O
?
show the reaction diagram
Q8GR22
-
-
?
tributyrin + H2O
butanoate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrin + H2O
butanoate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrin + H2O
butanoate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrin + H2O
butanoate + glycerol
show the reaction diagram
Q4PNS3
-
-
-
?
tributyrin + H2O
butanoate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrin + H2O
butanoate + glycerol
show the reaction diagram
B5THG6, -
-
-
-
?
tributyrine + H2O
?
show the reaction diagram
-
hydrolyzed at a lower rate than short and medium chain fatty acid esters
-
-
?
tributyrylglycerol + H2O
butyrate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrylglycerol + H2O
butyrate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrylglycerol + H2O
butyrate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrylglycerol + H2O
butyrate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrylglycerol + H2O
butyrate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrylglycerol + H2O
butyrate + glycerol
show the reaction diagram
-
-
-
-
?
tributyrylglycerol + H2O
butyrate + glycerol
show the reaction diagram
-
-
-
-
?
tricaproin + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
tricaproin + H2O
caproic acid + glycerol
show the reaction diagram
-
-
-
-
?
tricaproin + H2O
caproic acid + glycerol
show the reaction diagram
-
19.2% of the activity with tributyrin
-
-
?
tricaprylin + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
tricaprylin + H2O
caprylic acid + glycerol
show the reaction diagram
-
8.1% of the activity with tributyrin
-
-
?
trinotecan + H2O
?
show the reaction diagram
-
-
-
-
?
triolein + H2O
?
show the reaction diagram
-
-
-
-
?
triolein + H2O
oleic acid + glycerol
show the reaction diagram
-
-
-
-
?
tripropionin + H2O
?
show the reaction diagram
-
-
-
-
?
tripropionin + H2O
?
show the reaction diagram
-
-
-
-
?
tripropionin + H2O
propanoic acid + glycerol
show the reaction diagram
-
-
-
-
?
tripropionin + H2O
propionic acid + glycerol
show the reaction diagram
B5THG6, -
-
-
-
?
Tween 20 + H2O
?
show the reaction diagram
-
-
-
-
?
Tween 80 + H2O
?
show the reaction diagram
-
-
-
-
?
vinyl acetate + H2O
ethylenol + acetate
show the reaction diagram
-
-
-
-
?
vinyl acetate + H2O
ethylenol + acetate
show the reaction diagram
-
-
-
-
?
vinyl acetate + H2O
ethylenol + acetate
show the reaction diagram
-
-
-
-
?
vinyl acetate + H2O
ethylenol + acetate
show the reaction diagram
-
-
-
-
?
vinyl acetate + H2O
ethylenol + acetate
show the reaction diagram
-
-