Information on EC 3.1.1.1 - carboxylesterase

New: Word Map on EC 3.1.1.1
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Search Reference ID:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

EC NUMBER
COMMENTARY hide
3.1.1.1
-
RECOMMENDED NAME
GeneOntology No.
carboxylesterase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a carboxylic ester + H2O = an alcohol + a carboxylate
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis
-
-
hydrolysis of carboxylic ester
-
-
-
-
hydrolysis of carboxylic or thio-esters
hydrolysis of esters
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Drug metabolism - other enzymes
-
-
methyl indole-3-acetate interconversion
-
-
non-pathway related
-
-
retinol biosynthesis
-
-
SYSTEMATIC NAME
IUBMB Comments
carboxylic-ester hydrolase
Wide specificity. The enzymes from microsomes also catalyse the reactions of EC 3.1.1.2 (arylesterase), EC 3.1.1.5 (lysophospholipase), EC 3.1.1.6 (acetylesterase), EC 3.1.1.23 (acylglycerol lipase), EC 3.1.1.28 (acylcarnitine hydrolase), EC 3.1.2.2 (palmitoyl-CoA hydrolase), EC 3.5.1.4 (amidase) and EC 3.5.1.13 (aryl-acylamidase). Also hydrolyses vitamin A esters.
CAS REGISTRY NUMBER
COMMENTARY hide
9016-18-6
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain I6C-1, enzyme EstA
-
-
Manually annotated by BRENDA team
strain I6C-1, enzyme EstA
-
-
Manually annotated by BRENDA team
isoform CXE1
Uniprot
Manually annotated by BRENDA team
Aeropyrum pernix DSM 11879
-
Uniprot
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
Anoxybacillus sp.
-
-
-
Manually annotated by BRENDA team
strain SC-69828
-
-
Manually annotated by BRENDA team
Arthrobacter nitroguajacolicus
family VIII esterase
-
-
Manually annotated by BRENDA team
strain NRRL B-1973
-
-
Manually annotated by BRENDA team
strain NRRL B-1973
-
-
Manually annotated by BRENDA team
strain PW1
-
-
Manually annotated by BRENDA team
strain PW1
-
-
Manually annotated by BRENDA team
strain HS-1
-
-
Manually annotated by BRENDA team
strain HS-1
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
moderate thermophile, strain MAS2
-
-
Manually annotated by BRENDA team
strain 81-11
-
-
Manually annotated by BRENDA team
strain 81-11
-
-
Manually annotated by BRENDA team
strain BP-7, type B enzyme
-
-
Manually annotated by BRENDA team
strain BP-7, type B enzyme
-
-
Manually annotated by BRENDA team
strain 168, isoform CesA, CesB
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
strain SR22
-
-
Manually annotated by BRENDA team
Bacillus subtilis Thai I-8
strain Thai I-8, isoform NP
-
-
Manually annotated by BRENDA team
fragments; sweetpotato whitefly, strains SUD-S and B-ref
B3SST1 and B3SST2
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
gene EstC, formerly Pseudomonas marginata
SwissProt
Manually annotated by BRENDA team
gene lipA encodes a thermostable esterase
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Culex sp.
-
-
-
Manually annotated by BRENDA team
strain EM, enzyme PrbA
-
-
Manually annotated by BRENDA team
strain EM, enzyme PrbA
-
-
Manually annotated by BRENDA team
strain HB17
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
strain ZD112
SwissProt
Manually annotated by BRENDA team
strain ZD112
SwissProt
Manually annotated by BRENDA team
strain CL96
SwissProt
Manually annotated by BRENDA team
LILA, EstC
SwissProt
Manually annotated by BRENDA team
MG1363, EstA
-
-
Manually annotated by BRENDA team
cultivar Royal Gala AO3
-
-
Manually annotated by BRENDA team
strain 7-1W, AKU 163
-
-
Manually annotated by BRENDA team
strain 7-1W, AKU 163
-
-
Manually annotated by BRENDA team
strain YGJ1, isoforms E1 and E2
-
-
Manually annotated by BRENDA team
strain YGJ1, isoforms E1 and E2
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
juvenile, after exposure to chlorpyrifos or esfenvalerate
-
-
Manually annotated by BRENDA team
saw-toothed grain beetle, strains VOSCM and VOS48
-
-
Manually annotated by BRENDA team
ssp. shermanii, enzyme EstA, gene estA
-
-
Manually annotated by BRENDA team
strain TAC125
-
-
Manually annotated by BRENDA team
strain KCTC1767
Uniprot
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
IFO12996
SwissProt
Manually annotated by BRENDA team
strain B11-1, cold-adapted enzyme
SwissProt
Manually annotated by BRENDA team
strain KWI-56
-
-
Manually annotated by BRENDA team
strain Ant300
-
-
Manually annotated by BRENDA team
strain Ant300
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
Pyrobaculum sp.
-
SwissProt
Manually annotated by BRENDA team
Pyrobaculum sp. 1860
-
SwissProt
Manually annotated by BRENDA team
eastern subterranean termite, workers, 3 isozymes ME1, ME2, and ME3, which are B type serine esterases
-
-
Manually annotated by BRENDA team
strain SES-01, gene bioHs
UniProt
Manually annotated by BRENDA team
strain SES-01, gene bioHs
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
pest moth
-
-
Manually annotated by BRENDA team
subspecies Streptococcus equi equi
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
strain MT4
-
-
Manually annotated by BRENDA team
PLE
-
-
Manually annotated by BRENDA team
Thalassobacillus sp.
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
flour beetle, 2 strains, one is resistant to insecticide malathion possissing a malathion carboxylesterase, the other is suceptible to malathion possessing a non-specific carboxylesterase
-
-
Manually annotated by BRENDA team
Trichosporon sp.
strain DSMZ 11829
-
-
Manually annotated by BRENDA team
enzyme EstCE1, isolated from soil metagenome
-
-
Manually annotated by BRENDA team
analysis of alpha- and beta-esterase polymorphisms in different cultivars. alpha-Carboxylesterase EST-3 is absent in 61.7% of vines
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
physiological function
additional information
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(+)-1,2-O-isopropylidenglycerol caprylate + H2O
(+)-1,2-O-isopropylidenglycerol + caprylate
show the reaction diagram
(+)-menthylacetate + H2O
(+)-menthol + acetate
show the reaction diagram
-
enzyme is highly enantioselective for (+)-menthylacetate
-
-
?
(+)-trans 4-nitrophenyl crysanthemate + H2O
(+)-trans-crysanthemic acid + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
(+)-trans-ethyl crysanthemate + H2O
(+)-trans-crysanthemic acid + ethanol
show the reaction diagram
-
-
-
-
?
(+/-)-1,2-O-isopropylidenglycerol butanoate + H2O
(+/-)-1,2-O-isopropylidenglycerol + butanoate
show the reaction diagram
(+/-)-3-endo-acetyloxy-1,8-cineole + H2O
(1S,3S,4R)-(+)-3-acetyloxy-1,8-cineole + (1R,3R,4S)-(-)-3-hydroxy-1,8-cineole
show the reaction diagram
-
-
-
-
?
(-)-1,2-O-isopropylidenglycerol caprylate + H2O
(-)-1,2-O-isopropylidenglycerol + caprylate
show the reaction diagram
(1R)-bioresmethrin + H2O
?
show the reaction diagram
(1RS)-cis-permethrin + H2O
cis-dichlorochrysamthemic acid + 3-phenoxybenzyl alcohol
show the reaction diagram
(1RS)-trans-permethrin + H2O
trans-dichlorochrysamthemic acid + 3-phenoxybenzyl alcohol
show the reaction diagram
(2R)-fenvalerate + H2O
?
show the reaction diagram
-
-
-
?
(2S)-fenvalerate + H2O
?
show the reaction diagram
-
-
-
?
(alphaR)(2R)-fenvalerate + H2O
?
show the reaction diagram
-
-
-
?
(alphaR)(2S)-fenvalerate + H2O
?
show the reaction diagram
-
-
-
?
(alphaS)(2R)-fenvalerate + H2O
?
show the reaction diagram
-
-
-
?
(E)-2-hexenyl acetate + H2O
(Z)-2-hexenol + acetate
show the reaction diagram
-
-
-
-
?
(R)-2-(3-benzoylphenyl)propanoic methyl ester + H2O
methanol + (R)-2-(3-benzoylphenyl)propanoate
show the reaction diagram
-
when tested with the racemic substrate, the enzyme leads to the production of the R-configured acid with an enantiomeric excess of 80% at the conversion rate of 20% in 32 h
-
-
?
(R)-cyano(6-methoxy-2-naphthyl)methyl (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxy-2-naphthyl)methyl (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxy-2-naphthyl)methyl (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxy-2-naphthyl)methyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxynaphthalen-2-yl)methyl (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + (2R)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxynaphthalen-2-yl)methyl (1R,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,2S,3S)-2-(2,2-dichloroethenyl)-3-methylcyclopropanecarboxylate + (2R)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxynaphthalen-2-yl)methyl (1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + (2S)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxynaphthalen-2-yl)methyl (1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + (2S)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxynaphthalen-2-yl)methyl (2R)-2-(4-chlorophenyl)-3-methylbutanoate + H2O
(2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + (2R)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxynaphthalen-2-yl)methyl (2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (2R)-2-(4-chlorophenyl)-3-methylbutanoic acid
show the reaction diagram
-
-
-
?
(R)-cyano(6-methoxynaphthalen-2-yl)methyl (2S)-2-(4-chlorophenyl)-3-methylbutanoate + H2O
(2S)-2-(4-chlorophenyl)-3-methylbutanoic acid + (2R)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(R)-ketoprofen ethyl ester + H2O
(R)-ketoprofen + ethanol
show the reaction diagram
-
(R)-ketoprofen or (S)-ketoprofen is produced by esterase hydrolysis of the ester bond of (R,S)-ketoprofen ethyl ester
-
-
?
(R)-naproxen methyl ester + H2O
(R)-naproxen + methanol
show the reaction diagram
-
-
-
-
?
(S)-1-(6-fluoro-2-methyl-3,4-dihydroquinolin-1(2H)-yl)-2-(isoquinolin-5-yloxy)ethanone + H2O
(2S)-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline + (isoquinolin-5-yloxy)acetic acid
show the reaction diagram
(S)-cyano(6-methoxy-2-naphthyl)methyl (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxy-2-naphthyl)methyl (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxy-2-naphthyl)methyl (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxy-2-naphthyl)methyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + (2S)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + (2S)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate + (2S)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (2R)-2-(4-chlorophenyl)-3-methylbutanoate + H2O
(2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + (2S)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + H2O
(2R)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (2S)-2-(4-chlorophenyl)-3-methylbutanoic acid
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + H2O
(2S)-hydroxy(6-methoxy-2-naphthyl)acetonitrile + (2S)-2-(4-chlorophenyl)-3-methylbutanoic acid
show the reaction diagram
-
-
-
?
(S)-cyano(6-methoxynaphthalen-2-yl)methyl (2S)-2-(4-chlorophenyl)-3-methylbutanoate + H2O
(2S)-2-(4-chlorophenyl)-3-methylbutanoic acid + (2S)-hydroxy(6-methoxynaphthalen-2-yl)ethanenitrile
show the reaction diagram
-
-
-
?
(S)-ibuprofen methyl ester + H2O
(S)-ibuprofen + methanol
show the reaction diagram
(S)-ketoprofen ethyl ester + H2O
(S)-ketoprofen + ethanol
show the reaction diagram
(S)-naproxen methyl ester + H2O
(S)-naproxen + methanol
show the reaction diagram
(Z)-3-hexenyl acetate + H2O
(Z)-3-hexenol + acetate
show the reaction diagram
(Z)-3-hexenyl butyrate + H2O
(Z)-3-hexenol + butyrate
show the reaction diagram
-
-
-
-
?
(Z9,E11)-tetradec-9,11-enyl acetate + H2O
(Z9,E11)-tetradec-9,11-en-1-ol + acetate
show the reaction diagram
-
about 40% hydrolysis (native enzyme), 7.63% hydrolysis (recombinant enzyme)
-
-
?
(Z9,E12)-tetradec-9,12-enyl acetate + H2O
(Z9,E11)-tetradec-9,12-en-1-ol + acetate
show the reaction diagram
-
about 40% hydrolysis (native enzyme), 8.98% hydrolysis (recombinant enzyme)
-
-
?
1,2-dioctanoyl-glycerol + H2O
octanoate + glycerol
show the reaction diagram
-
-
-
-
-
1,2-O-dilauryl-rac-glycero-3-glutaric acid-resorufin ester + H2O
?
show the reaction diagram
1,3-dioctanoyl-glycerol + H2O
octanoate + glycerol
show the reaction diagram
-
-
-
-
?
1,4-diacetoxybenzene + H2O
?
show the reaction diagram
-
-
-
-
?
1-chloro-3-(1-naphthyloxy)-2-propanol acylester + H2O
(R)-1-chloro-3-(1-naphthyloxy)-2-propanol + carboxylic acid
show the reaction diagram
Trichosporon sp.
-
-
high stereoselectivity
-
?
1-monocaprylylglycerol + H2O
caprylic acid + glycerol
show the reaction diagram
1-monodecanoyl-glycerol + H2O
decanoate + glycerol
show the reaction diagram
-
-
-
-
-
1-monolauroyl-glycerol + H2O
lauric acid + glycerol
show the reaction diagram
1-monomyristoyl-glycerol + H2O
myristic acid + glycerol
show the reaction diagram
1-monooctanoyl-glycerol + H2O
octanoate + glycerol
show the reaction diagram
-
-
-
-
?
1-monooleyl glycerol + H2O
oleic acid + glycerol
show the reaction diagram
-
-
-
-
?
1-monopalmitin + H2O
palmitic acid + glycerol
show the reaction diagram
-
3.8% of the activity with tributyrin
-
-
?
1-monostearin + H2O
stearic acid + glycerol
show the reaction diagram
-
1.6% of the activity with tributyrin
-
-
?
1-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
1-naphthyl butanoate + H2O
1-naphthol + butanoate
show the reaction diagram
1-naphthyl butyrate + H2O
1-naphthol + butyrate
show the reaction diagram
1-naphthyl caprylate + H2O
1-naphthol + caprylate
show the reaction diagram
-
14% of the activity with 1-naphthyl acetate
-
-
?
1-naphthyl laurate + H2O
1-naphthol + laurate
show the reaction diagram
-
9% of the activity with 1-naphthyl acetate
-
-
?
1-naphthyl oleate + H2O
1-naphthol + oleate
show the reaction diagram
-
2% of the activity with 1-naphthyl acetate
-
-
?
1-naphthyl propionate + H2O
1-naphthol + propionate
show the reaction diagram
2'-ethylcarbonate-linked paclitaxel + H2O
paclitaxel + propanoate
show the reaction diagram
2,4-dinitrophenyl butyrate + H2O
2,4-dinitrophenol + butyrate
show the reaction diagram
2-acetoxy-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine + H2O
2-[2-oxo-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone + ?
show the reaction diagram
-
also called prasugrel, the hydrolysis is at least 25times greater with CE2 than CE1
also called R-95913
-
?
2-deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine + H2O
decitabine + ?
show the reaction diagram
-
-
-
-
?
2-monopalmitin + H2O
palmitic acid + glycerol
show the reaction diagram
-
2.6% of the activity with tributyrin
-
-
?
2-naphthyl acetate + H2O
2-naphthol + acetate
show the reaction diagram
2-naphthyl butyrate + H2O
2-naphthol + butyrate
show the reaction diagram
-
-
-
-
?
2-naphthyl propionate + H2O
2-naphthol + propionate
show the reaction diagram
2-nitrophenyl acetate + H2O
2-nitrophenol + acetate
show the reaction diagram
2-nitrophenyl butyrate + H2O
2-nitrophenol + butyrate
show the reaction diagram
2-nitrophenyl laurate + H2O
2-nitrophenol + laurate
show the reaction diagram
-
-
-
-
?
2-nitrophenylpropionate + H2O
2-nitrophenol + propionate
show the reaction diagram
-
-
-
-
?
2-octanyl acetate + H2O
2-octanol + acetate
show the reaction diagram
2-phenethyl acetate + H2O
2-phenylethanol + acetate
show the reaction diagram
-
-
-
-
?
2-phenyl-3-butyn-2-yl acetate
2-phenyl-3-butyn-2-ol + acetate
show the reaction diagram
-
-
-
-
2-phenyl-3-butyn-2-yl acetate + H2O
2-phenyl-3-butyn-2-ol + acetate
show the reaction diagram
2-phenyloxazolin-5-one + H2O
?
show the reaction diagram
2-thionaphthyl acetate + H2O
2-thionaphthol + acetate
show the reaction diagram
-
-
-
-
?
3'-D-phenylalanyl-gemcitabine + H2O
D-phenylalanine + gemcitabine
show the reaction diagram
-
-
-
-
?
3'-D-valyl-gemcitabine + H2O
D-valine + gemcitabine
show the reaction diagram
-
-
-
-
?
3'-L-isoleucyl-gemcitabine + H2O
L-isoleucine + gemcitabine
show the reaction diagram
-
-
-
-
?
3'-L-phenylalanyl-gemcitabine + H2O
L-phenylalanine + gemcitabine
show the reaction diagram
-
-
-
-
?
3'-L-valyl-gemcitabine + H2O
L-valine + gemcitabine
show the reaction diagram
-
-
-
-
?
3-acetoxypyridine + H2O
?
show the reaction diagram
-
-
-
-
?
3-methyl-1-pentyn-3-yl acetate + H2O
3-methyl-1-pentyn-3-ol + acetate
show the reaction diagram
3-nitrophenyl butyrate + H2O
3-nitrophenol + butyrate
show the reaction diagram
3-phenoxybenzyl (1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
3-phenoxybenzyl (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
3-phenoxybenzyl (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
3-phenoxybenzyl (1S,3S)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
(1S,3S)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylic acid + (3-phenoxyphenyl)methanol
show the reaction diagram
4'-chloroacetanilide + H2O
?
show the reaction diagram
-
-
-
-
?
4-aminobenzoic acid butyl ester + H2O
4-aminobenzoic acid + butanol
show the reaction diagram
-
-
-
-
?
4-aminobenzoic acid ethyl ester + H2O
4-aminobenzoic acid + ethanol
show the reaction diagram
-
-
-
-
?
4-aminobenzoic acid propyl ester + H2O
4-aminobenzoic acid + propanol
show the reaction diagram
-
-
-
-
?
4-hydroxylphenyl acetate + H2O
4-hydroxyphenol + acetate
show the reaction diagram
-
-
-
-
?
4-methylbenzyl acetate + H2O
4-methylbenzyl alcohol + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl (2E)-but-2-enoate + H2O
4-methylumbelliferone + (2E)-but-2-enoic acid
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl 3-phenoxybutanoate + H2O
4-methylumbelliferone + 3-phenoxybutanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl acetate + H2O
4-methylumbelliferol + acetate
show the reaction diagram
4-methylumbelliferyl acetate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
4-methylumbelliferyl butanoate + H2O
4-methylumbelliferol + butanoate
show the reaction diagram
-
enzyme activity in decreasing order: 4-methylumbelliferyl butanoate, 4-methylumbelliferyl heptanoate, 4-methylumbelliferyl oleate
-
-
?
4-methylumbelliferyl butanoate + H2O
4-methylumbelliferone + butanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferol + butyrate
show the reaction diagram
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl butyrate + H2O
4-methylumbelliferone + butyrate
show the reaction diagram
4-methylumbelliferyl cyclopentane carboxylate + H2O
4-methylumbelliferone + cyclopentane carboxylate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl heptanoate + H2O
4-methylumbelliferol + heptanoate
show the reaction diagram
4-methylumbelliferyl heptanoate + H2O
4-methylumbelliferone + heptanoate
show the reaction diagram
4-methylumbelliferyl hexanoate + H2O
4-methylumbelliferone + hexanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl laurate + H2O
4-methylumbelliferol + laurate
show the reaction diagram
-
-
-
?
4-methylumbelliferyl laurate + H2O
4-methylumbelliferone + laurate
show the reaction diagram
-
best substrate
-
-
?
4-methylumbelliferyl octanoate + H2O
4-methylumbelliferol + octanoate
show the reaction diagram
-
-
-
?
4-methylumbelliferyl octanoate + H2O
4-methylumbelliferone + octanoate
show the reaction diagram
4-methylumbelliferyl oleate + H2O
4-methylumbelliferol + oleate
show the reaction diagram
4-methylumbelliferyl p-trimethylammoniocinnamate chloride + H2O
4-methylumbelliferol + p-trimethylammoniocinnamate chloride
show the reaction diagram
4-methylumbelliferyl palmitate + H2O
4-methylumbelliferol + palmitate
show the reaction diagram
-
-
-
?
4-methylumbelliferyl palmitate + H2O
4-methylumbelliferone + palmitate
show the reaction diagram
4-methylumbelliferyl pentanoate + H2O
4-methylumbelliferone + pentanoate
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl propionate + H2O
4-methylumbelliferone + propionate
show the reaction diagram
-
-
-
-
?
4-nitroacetanilide + H2O
?
show the reaction diagram
-
-
-
-
?
4-nitrobenzoic acid methyl ester + H2O
4-nitrobenzoic acid + methanol
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 5.5
-
-
?
4-nitrophenyl 2-chloropropionate + H2O
4-nitrophenol + (S)-2-chloropropionic acid
show the reaction diagram
-
-
-
-
?
4-nitrophenyl acetate + H2O
4 nitrophenol + acetate
show the reaction diagram
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
show the reaction diagram
4-nitrophenyl acetate+ H2O
4-nitrophenol + acetate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl butanoate + H2O
4-nitrophenol + butanoate
show the reaction diagram
4-nitrophenyl butyrate + H2O
4 nitrophenol + butyrate
show the reaction diagram
most preferable substrate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
show the reaction diagram
4-nitrophenyl caprate + H2O
4-nitrophenol + caprate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl caprate + H2O
4-nitrophenol + capric acid
show the reaction diagram
4-nitrophenyl caproate + H2O
4-nitrophenol + caproate
show the reaction diagram
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
show the reaction diagram
4-nitrophenyl chrysanthemate + H2O
4-nitrophenol + chrysanthemate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl decanoate + H2O
4 nitrophenol + decanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
show the reaction diagram
4-nitrophenyl dodecanoate + H2O
4 nitrophenol + dodecanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl dodecanoate + H2O
4-nitrophenol + dodecanoate
show the reaction diagram
4-nitrophenyl heptanoate + H2O
4-nitrophenol + heptanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl hexadecanoate + H2O
4 nitrophenol + hexadecanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl hexadecanoate + H2O
4-nitrophenol + hexadecanoate
show the reaction diagram
4-nitrophenyl hexadecanoate + H2O
4-nitrophenol + palmitate
show the reaction diagram
-
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
show the reaction diagram
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
show the reaction diagram
4-nitrophenyl laurate + H2O
4-nitrophenol + lauric acid
show the reaction diagram
4-nitrophenyl methylphosphonate + H2O
4-nitrophenol + methylphosphonate
show the reaction diagram
-
-
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
show the reaction diagram
4-nitrophenyl myristate + H2O
4-nitrophenol + myristic acid
show the reaction diagram
4-nitrophenyl nonanoate + H2O
4-nitrophenol + nonanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl octanoate + H2O
4 nitrophenol + octanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl octanoate + H2O
4-nitrophenol + octanoate
show the reaction diagram
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
show the reaction diagram
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitic acid
show the reaction diagram
-
-
-
?
4-nitrophenyl pentanoate + H2O
4-nitrophenol + pentanoate
show the reaction diagram
4-nitrophenyl propanoate + H2O
4-nitrophenol + propanoate
show the reaction diagram
4-nitrophenyl propionate + H2O
4-nitrophenol + propionate
show the reaction diagram
4-nitrophenyl stearate + H2O
4-nitrophenol + stearate
show the reaction diagram
-
-
-
?
4-nitrophenyl tetradecanoate + H2O
4 nitrophenol + tetradecanoate
show the reaction diagram
-
-
-
?
4-nitrophenyl tetradecanoate + H2O
4-nitrophenol + tetradecanoate
show the reaction diagram
4-nitrophenyl valerate + H2O
4-nitrophenol + valerate
show the reaction diagram
5'-D-phenylalanyl-2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole + H2O
D-phenylalanine + 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole
show the reaction diagram
-
-
-
-
?
5'-D-phenylalanyl-gemcitabine + H2O
D-phenylalanine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-D-valyl-gemcitabine + H2O
D-valine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-L-isoleucyl-gemcitabine + H2O
L-isoleucine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-L-phenylalanyl-2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole + H2O
L-phenylalanine + 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole
show the reaction diagram
-
-
-
-
?
5'-L-phenylalanyl-gemcitabine + H2O
L-phenylalanine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-L-valyl-gemcitabine + H2O
L-valine + gemcitabine
show the reaction diagram
-
-
-
-
?
5'-O-cinnamoyl-2'-deoxy-5-fluorouridine + H2O
cinnamic acid + 2'-deoxy-5-fluorouridine
show the reaction diagram
-
-
-
-
?
5'-O-L-phenylalanyl-2'-deoxy-5-fluorouridine + H2O
L-phenylalanine + 2'-deoxy-5-fluorouridine
show the reaction diagram
-
-
-
-
?
6-methoxy-alpha-methyl-2-naphthaleneacetic acid methyl ester
(S)-naproxen + methanol
show the reaction diagram
Trichosporon sp.
-
i.e. naproxen methyl ester
high stereoselectivity
-
?
6-monoacetylmorphine + H2O
morphine + acetate
show the reaction diagram
-
hCE1 can metabolize the conversion of heroin to both 6-monoacetylmorphine and morphine. hCE1 is able to catalyze both reactions, but it is more efficient at the hydrolysis of heroin to 6-monoacetylmorphine, the first step of heroin metabolism
-
-
?
7-acetoxy-3-(2-benzothiazolyl)-4-cyanocoumarin + H2O
?
show the reaction diagram
low activity
-
?
7-amino cephalosporanic acid + H2O
?
show the reaction diagram
-
-
-
-
?
7-ethyl-10-(4-(1-piperidino)-1-amino)carbonyloxycampothecin + H2O
7-ethyl-10-hydroxycampothecin + 4-aminopiperidine-1-carboxylic acid
show the reaction diagram
-
i.e. NPC
-
-
?
7-ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxycampothecin + H2O
7-ethyl-10-hydroxycampothecin + 1,4'-bipiperidine-1'-carboxylic acid
show the reaction diagram
-
i.e. irinotecan, CPT-11
-
-
?
7-ethyl-10-(4-N-(5-aminopentanoic acid)-1-piperidino)carbonyloxycampothecin + H2O
7-ethyl-10-hydroxycampothecin + 4-((4-carboxybutyl)amino)piperidine-1-carboxylic acid
show the reaction diagram
-
i.e. APC
-
-
?
7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin + H2O
7-ethyl-10-hydroxycampothecin + ?
show the reaction diagram
7-ethyl-10[4-(1-piperidino)-1-piperdino]carbonyloxy-camptothecin + H2O
7-ethyl-10-hydroxy-camptothecin + ?
show the reaction diagram
7-[4-octylcarboxy-(3-hydroxy-3-methyl)-butyloxy]-coumarin + H2O
?
show the reaction diagram
-
-
-
-
?
acetanilide + H2O
acetate + aniline
show the reaction diagram
-
-
-
-
?
acetylsalicylic acid + H2O
salicylic acid + acetate
show the reaction diagram
alpha-cypermethrin + H2O
?
show the reaction diagram
-
-
-
?
alpha-naphthyl acetate + H2O
1-naphthol + acetate
show the reaction diagram
alpha-naphthyl acetate + H2O
alpha-naphthol + acetate
show the reaction diagram
alpha-naphthyl butanoate + H2O
alpha-naphthol + butanoate
show the reaction diagram
-
enzyme activity increases from acetate to propionate to butanoate substrate
-
-
?
alpha-naphthyl butyrate + H2O
alpha-naphthol + butyrate
show the reaction diagram
alpha-naphthyl caprate + H2O
alpha-naphthol + caprate
show the reaction diagram
-
-
-
?
alpha-naphthyl caproate + H2O
alpha-naphthol + caproate
show the reaction diagram
-
-
-
?
alpha-naphthyl caprylate + H2O
alpha-naphthol + caprylate
show the reaction diagram
alpha-naphthyl nonanoate + H2O
alpha-naphthol + nonanoate
show the reaction diagram
low activity
-
?
alpha-naphthyl propionate + H2O
alpha-naphthol + propionate
show the reaction diagram
alpha/beta-naphthyl butyrate + H2O
alpha/beta-naphthol + butyrate
show the reaction diagram
-
-
?
alpha/beta-naphthyl propionate + H2O
alpha/beta-naphthol + propionate
show the reaction diagram
best substrate
-
?
alpha/beta-naphthyl valerate + H2O
alpha/beta-naphthol + valerate
show the reaction diagram
-
-
?
ampicillin + H2O
?
show the reaction diagram
-
-
-
-
?
anisamidobutyric acid + H2O
?
show the reaction diagram
-
-
-
-
?
aspirin + H2O
acetate + salicylate
show the reaction diagram
benazepril + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Gly-farnesyl-L-cysteine methyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
benzyl (trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate) + H2O
benzol + trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate
show the reaction diagram
-
i.e. benzyl cetraxate
-
?
benzyl acetate + H2O
benzene + acetate
show the reaction diagram
-
-
-
-
?
benzyl acetate + H2O
benzyl alcohol + acetate
show the reaction diagram
-
-
-
-
?
benzyl propionate + H2O
benzene + propionate
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-D-Tyr-p-nitrophenyl ester + H2O
benzyloxycarbonyl-D-Tyr + 4-nitrophenol
show the reaction diagram
benzyloxycarbonyl-Gly-p-nitrophenyl ester + H2O
benzyloxycarbonyl-Gly + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-L-Ala-p-nitrophenyl ester + H2O
benzyloxycarbonyl-L-Ala + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-L-Tyr-p-nitrophenyl ester + H2O
benzyloxycarbonyl-L-Tyr + 4-nitrophenol
show the reaction diagram
beta-naphthyl acetate + H2O
beta-naphthol + acetate
show the reaction diagram
beta-naphthyl caproate + H2O
beta-naphthol + caproate
show the reaction diagram
low activity
-
?
beta-phenethyl acetate + H2O
?
show the reaction diagram
-
-
-
-
?
beta-thionaphthyl acetate + H2O
beta-thionaphthol + acetate
show the reaction diagram
-
-
-
-
?
betamethasone valerate + H2O
betamethasone + valerate
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 0.21
-
-
?
bioresmethrin + H2O
?
show the reaction diagram
bis(2-ethylhexyl)phthalate + H2O
?
show the reaction diagram
-
-
-
-
?
bisphenyl carbonate + H2O
?
show the reaction diagram
-
-
-
-
?
butanilcain + H2O
?
show the reaction diagram
-
-
-
-
?
butyl 2-(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenoxy)propanoate + H2O
2-(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenoxy)propanoic acid + butanol
show the reaction diagram
i.e. fluazifop butyl
-
-
?
butyl acetate + H2O
butanol + acetate
show the reaction diagram
butyl benzoate + H2O
benzoate + butanol
show the reaction diagram
butyl octanoate + H2O
butanol + octanoate
show the reaction diagram
-
-
?
butyl paraben + H2O
butanol + 4-hydroxybenzoate
show the reaction diagram
-
-
-
?
butyrylthiocholine + H2O
butyric acid + thiocholine
show the reaction diagram
camostat mesilate + H2O
?
show the reaction diagram
-
-
-
-
?
capecitabin + H2O
?
show the reaction diagram
capric acid + sn-glycerol
1-monocaprin
show the reaction diagram
-
the carboxylesterase performs also the esterification reaction using capric acid and glycerol as substrates resulting in formation of 1-monocaprin, product analysis by HPLC and method optimization, overview
-
-
?
capsaicin + H2O
?
show the reaction diagram
-
-
-
-
?
carboxyfluorescein diacetate + H2O
?
show the reaction diagram
-
-
-
-
?
carboxyfluorescein diacetate + H2O
carboxyfluorescein + acetate
show the reaction diagram
-
-
-
-
?
cefazolin + H2O
(6R,7R)-7-amino-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid + (1H-tetrazol-1-yl)acetic acid
show the reaction diagram
-
-
-
-
?
cephaloridine + H2O
(6R,7R)-7-amino-8-oxo-3-[(pyridin-1-ium-1-yl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate + (thiophen-2-yl)acetic acid
show the reaction diagram
-
-
-
-
?
cephalothin + H2O
acetate + deacetylcephalothin
show the reaction diagram
-
-
-
-
?
chlorpyrifos + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
cholesterol ester + H2O
?
show the reaction diagram
cholesterol oleate + H2O
cholesterol + oleate
show the reaction diagram
cholesteryl oleate + H2O
cholesterol + oleate
show the reaction diagram
-
-
-
-
?
cilazapril + H2O
?
show the reaction diagram
cis-cypermethrin + H2O
?
show the reaction diagram
-
-
-
?
cis-permethrin + H2O
?
show the reaction diagram
clodinafop-propargyl + H2O
? + prop-2-yn-1-ol
show the reaction diagram
-
-
-
-
?
clopidogrel + H2O
(2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid + methanol
show the reaction diagram
cocaine + H2O
ecgonine methyl ester + benzoate
show the reaction diagram
cocaine + H2O
O-benzoylecgonine + methanol
show the reaction diagram
CPT-11 + H2O
SN-38 + 1,4'-bipiperidine-1'-carboxylic acid + CO2
show the reaction diagram
CPT-11 + H2O
SN-38 + ?
show the reaction diagram
cyano(3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
hydroxy(3-phenoxyphenyl)acetonitrile + 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
cyano(6-methoxy-2-naphthyl)methyl 2,2,3,3-tetramethylcyclopropanecarboxylate + H2O
hydroxy(6-methoxy-2-naphthyl)acetonitrile + 2,2,3,3-tetramethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
cyano(6-methoxy-2-naphthyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + H2O
hydroxy(6-methoxy-2-naphthyl)acetonitrile + 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
cyano(6-methoxy-2-naphthyl)methyl butanoate + H2O
hydroxy(6-methoxy-2-naphthyl)acetonitrile + butanoate
show the reaction diagram
-
-
-
?
cyano(6-methoxynaphthalen-2-yl)methyl (2S)-2-(4-chlorophenyl)-3-methylbutanoic acid + H2O
(2R)-2-(4-chlorophenyl)-3-methylbutanoic acid + hydroxy(6-methoxy-2-naphthyl)acetonitrile
show the reaction diagram
-
-
-
?
cyano(6-methoxynaphthalen-2-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylic acid + H2O
hydroxy(6-methoxy-2-naphthyl)acetonitrile + 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylic acid
show the reaction diagram
-
-
-
?
cyclic poly(ethylene terephthalate) trimer + H2O
?
show the reaction diagram
cyclohexyl 4-nitrophenyl methylphosphonate + H2O
?
show the reaction diagram
-
-
-
-
?
cypermethrin + H2O
?
show the reaction diagram
D-glucose pentaacetate + H2O
? + acetate
show the reaction diagram
-
-
-
-
?
D-methyl phenidate + H2O
?
show the reaction diagram
-
-
-
-
?
D-methylphenidate + H2O
methanol + phenyl(piperidin-2-yl)acetate
show the reaction diagram
-
-
-
-
?
D-Tyr ethyl ester + H2O
D-Tyr + ethanol
show the reaction diagram
-
-
-
-
?
D-xylose tetraacetate + H2O
? + acetate
show the reaction diagram
-
-
-
-
?
delapril + H2O
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)glycine + ethanol
show the reaction diagram
-
-
-
-
?
deltamethrin + H2O
3-phenoxybenzaldehyde + (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylate
show the reaction diagram
derapril + H2O
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)glycine + ethanol
show the reaction diagram
dicaprin + H2O
?
show the reaction diagram
-
-
-
-
?
diethyl (6-methoxynaphthalen-2-yl)(methyl)propanedioate + H2O
ethanol + (2S)-3-ethoxy-2-(6-methoxynaphthalen-2-yl)-2-methyl-3-oxopropanoic acid
show the reaction diagram
diethyl methyl(phenyl)propanedioate + H2O
ethanol + (2S)-3-ethoxy-2-methyl-3-oxo-2-phenylpropanoic acid
show the reaction diagram
diethyl succinate + H2O
?
show the reaction diagram
-
-
-
-
-
diethyl-4-methylumbelliferyl phosphate + H2O
?
show the reaction diagram
-
-
-
-
?
diltiazem + H2O
?
show the reaction diagram
-
-
-
-
?
dimethyl cis-cyclohex-4-ene-1,2-dicarboxylate + H2O
methyl hydrogen (1S,2R)-cyclohex-4-ene-1,2-dicarboxylate + methanol
show the reaction diagram
-
enantioselectivity, 98% at 25C, 96% at 50C
94-97% of the R-enantiomer
ir
diolein + H2O
?
show the reaction diagram
DL-methyl 2-chloropropionate + H2O
?
show the reaction diagram
DL-methylphenidate + H2O
methanol + phenyl(piperidin-2-yl)acetate
show the reaction diagram
-
-
-
-
?
enalapril + H2O
?
show the reaction diagram
-
-
-
-
?
epsilon-caprolacone + H2O
hexanoate
show the reaction diagram
-
the enzyme catalyzes a ring-opening polymerization of epsilon-caprolactone
-
-
?
epsilon-cypermethrin + H2O
?
show the reaction diagram
-
-
-
?
estrone acetate + H2O
estrone + acetate
show the reaction diagram
-
-
-
-
?
ethanol + acetate
ethyl acetate
show the reaction diagram
-
esterification reaction
-
?
ethanol + acetate
ethyl acetate + H2O
show the reaction diagram
ester formation
-
?
ethanol + acetyl-CoA
ethyl acetate + CoA + H2O
show the reaction diagram
ester formation
-
?
ethanol + butyrate
ethyl butanoate + H2O
show the reaction diagram
ester formation
-
?
ethyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate + H2O
ethanol + (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
show the reaction diagram
ethyl (2S)-2-phenylpropanoate + H2O
ethanol + (2S)-2-phenylpropanoate
show the reaction diagram
ethyl (trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate) + H2O
ethanol + trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate
show the reaction diagram
ethyl 2-(4-((6-chloro-1,3-benzothiazol-2-yl)oxy)phenoxy)propanoate + H2O
2-(4-((6-chloro-1,3-benzothiazol-2-yl)oxy)phenoxy)propanoic acid + ethanol
show the reaction diagram
i.e. fenthiaprop ethyl
-
-
?
ethyl 2-(4-((6-chloro-1,3-benzoxazol-2-yl)oxy)phenoxy)propanoate + H2O
2-(4-((6-chloro-1,3-benzoxazol-2-yl)oxy)phenoxy)propanoic acid + ethanol
show the reaction diagram
i.e. fenoxaprop ethyl
-
-
?
ethyl 2-hydroxy-4-phenylbutanoate + H2O
2-hydroxy-4-phenylbutanoate + ethanol
show the reaction diagram
-
enantiopreference for (S)-isomer with enantiomeric excess of 80%
-
?
ethyl 2-naphthyl acetate + H2O
?
show the reaction diagram
-
-
-
-
?
ethyl 3,4-dihydroxybenzoate + H2O
ethanol + 3,4-dihydroxybenzoate
show the reaction diagram
-
low activity
-
?
ethyl 3-hydroxybenzoate + H2O
ethanol + 3-hydroxybenzoate
show the reaction diagram
-
-
-
?
ethyl 3-methoxybenzoate + H2O
ethanol + 3-methoxybenzoate
show the reaction diagram
-
-
-
?
ethyl 4-hydroxybenzoate + H2O
ethanol + 4-hydroxybenzoate
show the reaction diagram
-
-
-
?
ethyl 4-methoxybenzoate + H2O
ethanol + 4-methoxybenzoate
show the reaction diagram
-
-
-
?
ethyl 4-nitrophenyl acetate + H2O
?
show the reaction diagram
-
-
-
-
?
ethyl 4-nitrophenyl methylphosphonate + H2O
?
show the reaction diagram
-
-
-
-
?
ethyl acetate + H2O
ethanol + acetate
show the reaction diagram
ethyl benzoate + H2O
ethanol + benzoate
show the reaction diagram
-
-
-
?
ethyl bromoacetate + H2O
ethanol + bromoacetate
show the reaction diagram
-
-
-
-
?
ethyl butanoate + H2O
butanoate + ethanol
show the reaction diagram
-
-
-
-
?
ethyl butanoate + H2O
ethanol + butanoate
show the reaction diagram
ethyl butyrate + H2O
ethanol + butanoate
show the reaction diagram
ethyl butyrate + H2O
ethanol + butyrate
show the reaction diagram
ethyl butyrylacetate + H2O
?
show the reaction diagram
-
-
-
-
?
ethyl caproate + H2O
ethanol + caproate
show the reaction diagram
-
-
-
?
ethyl caprylate + H2O
ethanol + caprylate
show the reaction diagram
-
-
-
-
?
ethyl chloroacetate + H2O
ethanol + chloroacetate
show the reaction diagram
-
-
-
-
?
ethyl D-pantothenate + H2O
ethanol + D-pantothenate
show the reaction diagram
-
-
-
?
ethyl DL-beta-acetylthioisobutyrate + H2O
?
show the reaction diagram
ethyl fluoroacetate + H2O
ethanol + fluoroacetate
show the reaction diagram
-
-
-
-
?
ethyl hexanoate + H2O
ethanol + hexanoate
show the reaction diagram
ethyl iodoacetate + H2O
ethanol + iodoacetate
show the reaction diagram
-
-
-
-
?
ethyl L-pantothenate + H2O
ethanol + L-pantothenate
show the reaction diagram
-
-
-
?
ethyl laurate + H2O
ethanol + laurate
show the reaction diagram
-
-
?
ethyl myristate + H2O
ethanol + myristate
show the reaction diagram
-
-
?
ethyl octanoate + H2O
ethanol + octanoate
show the reaction diagram
-
-
?
ethyl paraben + H2O
ethanol + 4-hydroxybenzoate
show the reaction diagram
ethyl pelargonate + H2O
ethanol + pelargonate
show the reaction diagram
-
-
?
ethyl pentanoate + H2O
ethanol + pentanoate
show the reaction diagram
ethyl propionate + H2O
ethanol + propionate
show the reaction diagram
ethyl thiolacetate + H2O
ethanol + ethanethioic S-acid
show the reaction diagram
-
-
-
-
?
ethyl valerate + H2O
ethanol + valerate
show the reaction diagram
-
-
-
?
ethyl valerate + H2O
ethanol + valeric acid
show the reaction diagram
-
-
-
?
ethylene glycol dibenzoate + H2O
?
show the reaction diagram
fenitrothion + H2O
?
show the reaction diagram
-
poor substrate
-
-
?
fenvalerate + H2O
?
show the reaction diagram
-
-
-
?
fluorescein diacetate + H2O
?
show the reaction diagram
fluorescein diacetate + H2O
fluorescein + acetate
show the reaction diagram
-
-
-
-
?
geranyl acetate + H2O
geraniol + acetate
show the reaction diagram
-
-
-
-
?
glucose pentaacetate + H2O
?
show the reaction diagram
glyceryl tributyrate + H2O
?
show the reaction diagram
glyceryl tridecanoate + H2O
?
show the reaction diagram
glyceryl trihexanoate + H2O
?
show the reaction diagram
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl trioctanoate + H2O
?
show the reaction diagram
activity with mutant enzyme expressed from the gene that has a deletion of about 60 residues at the N terminus
-
-
?
glyceryl trioleate + H2O
?
show the reaction diagram
heptyl acetate + H2O
heptanol + acetate
show the reaction diagram
-
-
-
-
?
heroin + H2O
6-monoacetylmorphine + acetate
show the reaction diagram
hexyl acetate + H2O
hexanol + acetate
show the reaction diagram
hexyl valerate + H2O
hexanol + valeric acid
show the reaction diagram
-
-
-
?
hydrocinnamoyl farnesyl-L-cysteine methyl ester + H2O
N-(3-phenylpropanoyl)-S-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-L-cysteine + methanol
show the reaction diagram
-
-
-
-
?
hydroxyethylflurbiprofen + H2O
ethanol + flurbiprofen
show the reaction diagram
hydroxypropylflurbiprofen + H2O
propanol + flurbiprofen
show the reaction diagram
imidapril + H2O
?
show the reaction diagram
imidapril + H2O
imidaprilat + ?
show the reaction diagram
indoxyl acetate + H2O
?
show the reaction diagram
-
-
-
-
?
indoxyl acetate + H2O
indol-3-ol + acetate
show the reaction diagram
-
-
-
-
?
irinotecan + H2O
7-ethyl-10-hydroxycampothecin + 1,4'-bipiperidine-1'-carboxylic acid
show the reaction diagram
irinotecan + H2O
?
show the reaction diagram
irinotecan-7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin + H2O
?
show the reaction diagram
isobutyl 4-nitrophenyl methylphosphonate + H2O
?
show the reaction diagram
-
-
-
-
?
isobutyl 4-nitrophenyl methylphosphonate + H2O
isobutyl 4-nitrophenol + methylphosphonate
show the reaction diagram
-
-
-
-
?
isobutyl acetate + H2O
isobutanol + acetate
show the reaction diagram
-
-
-
?
isocarbophos + H2O
?
show the reaction diagram
-
-
-
-
?
isopentyl octanoate + H2O
isopentanol + octanoate
show the reaction diagram
-
-
?
isopropyl (trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate) + H2O
isopropanol + trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate
show the reaction diagram
isopropyl 4-nitrophenyl methylphosphonate + H2O
?
show the reaction diagram
-
-
-
-
?
isopropyl acetate + H2O
isopropanol + acetate
show the reaction diagram
isopropyl octanoate + H2O
isopropanol + octanoate
show the reaction diagram
-
-
?
ispopropenyl acetate + H2O
isopropenol + acetate
show the reaction diagram
-
-
-
-
?
ketoprofen ethyl ester + H2O
ketoprofen + ethanol
show the reaction diagram
-
-
-
-
?
ketoprofen ethyl ester + H2O
R-ketoprofen + ethanol
show the reaction diagram
-
-
R-isomer is main product of keratinocyte enzyme
-
?
L-methyl phenidate + H2O
?
show the reaction diagram
-
-
-
-
?
L-phenylalanine butyl ester + H2O
L-phenylalanine + butanol
show the reaction diagram
-
-
-
-
?
L-phenylalanine ethyl ester + H2O
L-phenylalanine + ethanol
show the reaction diagram
-
-
-
-
?
L-Tyr ethyl ester + H2O
L-Tyr + ethanol
show the reaction diagram
linalyl acetate + H2O
linalool + acetate
show the reaction diagram
malathion + H2O
?
show the reaction diagram
malathion + H2O
malathion alpha-monocarboxylic acid + malathion beta-monocarboxylic acid
show the reaction diagram
-
-
-
-
?
meperidine + H2O
?
show the reaction diagram
methanethiol + acetyl-CoA
methanethioacetate + coenzyme A
show the reaction diagram
ester formation
-
?
methyl (-)-2-(3-benzoylphenyl)propionate + H2O
(-)-2-(3-benzoylphenyl)propionate + methanol
show the reaction diagram
-
-
-
?
methyl (trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate) + H2O
methanol + trans-4-[[4-(aminomethyl)cyclohexyl]carbonyl]oxybenzen-propionate
show the reaction diagram
methyl 1H-indole-3-carboxylate + H2O
methanol + 1H-indole-3-carboxylate
show the reaction diagram
-
-
-
-
methyl 2-(4-(2,4-dichlorophenoxy)phenoxy)propanoate + H2O
2-(4-(2,4-dichlorophenoxy)phenoxy)propanoic acid + methanol
show the reaction diagram
i.e. Diclofop methyl
-
-
?
methyl 2-aminobenzoate + H2O
methanol + 2-aminobenzoate
show the reaction diagram
-
-
-
?
methyl 2-hydroxybenzoate + H2O
methanol + 2-hydroxybenzoate
show the reaction diagram
-
very low activity
-
?
methyl 3,5-dihydroxybenzoate + H2O
methanol + 3-hydroxybenzoate
show the reaction diagram
-
low activity
-
?
methyl 3-(4-hydroxyphenyl)propionate + H2O
methanol + 3-(4-hydroxyphenyl)propionate
show the reaction diagram
-
-
-
?
methyl 3-hydroxybenzoate + H2O
methanol + 3-hydroxybenzoate
show the reaction diagram
-
-
-
?
methyl 4-aminobenzoate + H2O
methanol + 4-aminobenzoate
show the reaction diagram
-
-
-
?
methyl 4-nitrobenzoate + H2O
4-nitrobenzoate + methanol
show the reaction diagram
-
specific substrate for isoform ES1
-
-
?
methyl acetate
methanol + acetate
show the reaction diagram
-
poor substrate
-
-
?
methyl acetate + H2O
methanol + acetate
show the reaction diagram
methyl benzoate + H2O
methanol + benzoate
show the reaction diagram
-
low activity
-
?
methyl butanoate + H2O
methanol + butanoate
show the reaction diagram
methyl butyrate + H2O
methanol + butanoate
show the reaction diagram
preferred substrate. The enzyme preferentially hydrolyzes esters of short-chain fatty acids (C2C4) and especially those of medium chain (C5C6) fatty acids with short chain alcohols
-
-
?
methyl butyrate + H2O
methanol + butyrate
show the reaction diagram
methyl caprate + H2O
methanol + decanoate
show the reaction diagram
-
-
-
-
?
methyl D-pantothenate + H2O
methanol + D-pantothenate
show the reaction diagram
-
-
-
?
methyl decanoate + H2O
methanol + decanoic acid
show the reaction diagram
-
-
-
-
?
methyl DL-beta-acetylthioisobutyrate + H2O
D-beta-acetylthioisobutyrate + methanol
show the reaction diagram
methyl hexanoate + H2O
methanol + hexanoate
show the reaction diagram
methyl hexanoate + H2O
methanol + hexanoic acid
show the reaction diagram
-
-
-
-
?
methyl L-pantothenate + H2O
methanol + L-pantothenate
show the reaction diagram
-
-
-
?
methyl laurate + H2O
methanol + lauric acid
show the reaction diagram
-
-
-
-
?
methyl myristate + H2O
methanol + myristic acid
show the reaction diagram
-
-
-
-
?
methyl octanoate + H2O
methanol + octanoate
show the reaction diagram
methyl octanoate + H2O
methanol + octanoic acid
show the reaction diagram
-
-
-
-
?
methyl paraben + H2O
methanol + 4-hydroxybenzoate
show the reaction diagram
methyl paraoxon + H2O
?
show the reaction diagram
-
-
-
-
?
methyl propionate + H2O
methanol + propionate
show the reaction diagram
methyl salicylate + H2O
methanol + salicylate
show the reaction diagram
-
-
-
-
?
methyl salicylate + H2O
salicylic acid + methanol
show the reaction diagram
-
ratio of the rates of hydrolysis in liver to intestine 15.3
-
-
?
methyl vanillate + H2O
methanol + vanillate
show the reaction diagram
-
-
-
?
methyl-2,4-dichlorophenoxyacetate + H2O
2,4-dichlorophenoxyacetic acid + methanol
show the reaction diagram
-
i.e. 2,4-D-methyl
activation of pro-herbicide to phytotoxic acid. Isoform CXE12 is the major carboxyesterase responsible for activation
-
?
methylphenidate + H2O
?
show the reaction diagram
methylprednisolone 21-hemisuccinate + H2O
?
show the reaction diagram
methylumbelliferyl acetate + H2o
methylumbelliferone + acetate
show the reaction diagram
-
-
-
-
?
monobutyl phthalate + H2O
phthalate + butanol
show the reaction diagram
monocaprin + H2O
glycerol + caproate
show the reaction diagram
-
-
-
-
?
monoelaidin + H2O
elaidic acid + glycerol
show the reaction diagram
-
-
-
-
-
monoolein + H2O
glycerol + oleic acid
show the reaction diagram
monopalmitoin + H2O
glycerol + palmitoleic acid
show the reaction diagram
-
-
-
-
?
monopentyl phthalate + H2O
phthalate + pentanol
show the reaction diagram
monopropyl phthalate + H2O
phthalate + propanol
show the reaction diagram
mycophenolate mofetil + H2O
mycophenolic acid + mofetil
show the reaction diagram
-
prodrug, activation
-
-
?
N-(4-nitrobenzoyl)-S-trans,trans-farnesyl-L-cysteine methyl ester + H2O
?
show the reaction diagram
N-acetyl L-phenylalanine ethyl ester + H2O
N-acetyl L-phenylalanine + ethanol
show the reaction diagram
-
-
-
-
?
N-acetyl-L-Ala-1-naphthyl ester + H2O
N-acetyl-L-Ala + 1-naphthol
show the reaction diagram
-
-
-
-
?
N-acetyl-L-phenylalanine methyl ester + H2O
N-acetyl-L-phenylalanine + methanol
show the reaction diagram
-
-
-
-
?
n-butyl acetate + H2O
n-butanol + acetate
show the reaction diagram
-
-
-
-
?
n-butyl benzoate + H2O
n-butanol + benzoate
show the reaction diagram
-
-
-
?
n-butyl n-butyrate + H2O
n-butanol + n-butyrate
show the reaction diagram
n-butyryl salicylate + H2O
n-butanol + salicylate
show the reaction diagram
-
-
-
-
?
n-decanoyl salicylate + H2O
? + salicylate
show the reaction diagram
-
-
-
-
?
N-ethylglycine xylidide + H2O
?
show the reaction diagram
-
-
-
-
?
n-heptyl acetate + H2O
n-heptanol + acetate
show the reaction diagram
-
-
-
-
?
n-hexanoyl salicylate + H2O
n-hexanol + salicylate
show the reaction diagram
-
-
-
-
?
n-hexyl acetate + H2O
n-hexanol + acetate
show the reaction diagram
n-octanoyl salicylate + H2O
? + salicylate
show the reaction diagram
-
-
-
-
?
n-octyl acetate + H2O
n-octanol + acetate
show the reaction diagram
-
-
-
-
?
n-pentyl acetate + H2O
n-pentanol + acetate
show the reaction diagram
-
-
-
-
?
N-propyl acetate + H2O
n-propanol + acetate
show the reaction diagram
-
-
-
-
?
n-propyl D-pantothenate + H2O
n-propanol + D-pantothenate
show the reaction diagram
-
-
-
?
n-propyl L-pantothenate + H2O
n-propanol + L-pantothenate
show the reaction diagram
-
best substrate
-
?
n-propyl salicylate + H2O
n-propanol + salicylate
show the reaction diagram
-
-
-
-
?
n-valeryl salicylate + H2O
n-pentanol + salicylate
show the reaction diagram
-
-
-
-
?
naphthyl acetate + H2O
naphthol + acetate
show the reaction diagram
nitrocefin + H2O
?
show the reaction diagram
-
i.e. 3-(2,4-dinitrosyl)-(6R,7R)-7-(2-thienylacetamido)-ceph-3-em-4-carboxylic acid
-
-
?
nonyl acetate + H2O
nonanol + acetate
show the reaction diagram
-
-
-
-
?
O-butyryl propranolol + H2O
butanoate + propranolol
show the reaction diagram
octyl acetate + H2O
octanol + acetate
show the reaction diagram
-
-
-
?
oleoyl-CoA + H2O
oleic acid + CoA
show the reaction diagram
oseltamivir + H2O
?
show the reaction diagram
oxybutynin + H2O
2-cyclohexyl-2-phenylglycolic acid + ?
show the reaction diagram
-
-
-
-
?
oxybutynin + H2O
?
show the reaction diagram
-
-
-
-
?
p-nitrophenol butanoate + H2O
p-nitrophenol + butanoate
show the reaction diagram
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
show the reaction diagram
p-nitrophenyl butanoate + H2O
p-nitrophenol + butanoate
show the reaction diagram
p-nitrophenyl butyrate
p-nitrophenol + butyrate
show the reaction diagram
p-nitrophenyl butyrate + H2O
p-nitrophenol + butanoate
show the reaction diagram
-
-
-
-
p-nitrophenyl caprate
p-nitrophenol + caprate
show the reaction diagram
p-nitrophenyl caproate
p-nitrophenol + caproate
show the reaction diagram
p-nitrophenyl caproate + H2O
p-nitrophenol + caproate
show the reaction diagram
p-nitrophenyl caprylate + H2O
p-nitrophenol + caprylate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl decanoate
p-nitrophenol + octanoate
show the reaction diagram
p-nitrophenyl hexanoate + H2O
p-nitrophenol + hexanoate
show the reaction diagram
p-nitrophenyl laurate
p-nitrophenol + laurate
show the reaction diagram
p-nitrophenyl myristate + H2O
p-nitrophenol + myristate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl octanoate
p-nitrophenol + decanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl octanoate
p-nitrophenol + octanoate
show the reaction diagram
-
-
-
-
?
p-nitrophenyl palmitate
p-nitrophenol + palmitate
show the reaction diagram
-
-
-
?
p-nitrophenyl palmitate + H2O
p-nitrophenol + palmitate
show the reaction diagram
p-nitrophenyl pentanoate + H2O
p-nitrophenol + pentanoate
show the reaction diagram
-
and substrates with longer acyl chains, hydrolysis proceeds in biophasic manner
-
-
?
p-nitrophenyl propionate
p-nitrophenol + propionate
show the reaction diagram
-
-
-
-
p-nitrophenyl stearate
p-nitrophenol + stearate
show the reaction diagram
-
-
-
-
p-nitrophenyl stearate + H2O
p-nitrophenol + stearate
show the reaction diagram
-
50% of the activity with p-nitrophenyl decanoate
-
-
?
p-nitrophenyl valerate + H2O
p-nitrophenol + valeric acid
show the reaction diagram
p-tolyl octanoate + H2O
p-toluol + octanoate
show the reaction diagram
-
-
?
palmitin + H2O
?
show the reaction diagram
-
-
-
-
?
palmitoyl-CoA
CoA + palmitate
show the reaction diagram
-
-
-
-
palmitoyl-CoA + H2O
palmitic acid + CoA
show the reaction diagram
paraoxon + H2O
?
show the reaction diagram
penicillin G + H2O
6-aminopenicillanic acid + phenylacetic acid
show the reaction diagram
-
-
-
-
?
pentyl acetate + H2O
pentanol + acetate
show the reaction diagram
pentyl octanoate + H2O
pentanol + octanoate
show the reaction diagram
-
-
?
pentyl PABC-Doxazolidine + H2O
PABC-Doxazolidine + pentanol
show the reaction diagram
-
-
-
-
?
pentyl valerate + H2O
pentanol + valeric acid
show the reaction diagram
not hydrolysed in the absence of Triton X-100
-
-
?
permethrin + H2O
?
show the reaction diagram
phenolphthalein dibutyrate + H2O
?
show the reaction diagram