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Literature summary for 3.1.1.1 extracted from
- Purification and enzymatic properties of rat serum carboxylesterase (1978), J. Biochem., 84, 1325-1333.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| DFP | - |
Rattus norvegicus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0086 | - |
4-nitrophenyl myristate | - |
Rattus norvegicus | |
| 0.067 | - |
4-nitrophenyl laurate | - |
Rattus norvegicus | |
| 0.15 | - |
4-nitrophenyl octanoate | - |
Rattus norvegicus | |
| 0.47 | - |
4-nitrophenyl hexanoate | - |
Rattus norvegicus | |
| 0.53 | - |
4-nitrophenyl pentanoate | - |
Rattus norvegicus | |
| 1.6 | - |
4-nitrophenyl butyrate | - |
Rattus norvegicus | |
| 2.3 | - |
4-nitrophenyl acetate | - |
Rattus norvegicus | |
| 3.3 | - |
4-nitrophenyl propionate | - |
Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 84000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| serum | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 49.5 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl acetate + H2O | - |
Rattus norvegicus | 4-nitrophenol + acetate | - |
? | |
| 4-nitrophenyl butyrate + H2O | - |
Rattus norvegicus | 4-nitrophenol + butyrate | - |
? | |
| 4-nitrophenyl hexanoate + H2O | - |
Rattus norvegicus | 4-nitrophenol + hexanoate | - |
? | |
| 4-nitrophenyl laurate + H2O | - |
Rattus norvegicus | 4-nitrophenol + lauric acid | - |
? | |
| 4-nitrophenyl myristate + H2O | - |
Rattus norvegicus | 4-nitrophenol + myristic acid | - |
? | |
| 4-nitrophenyl octanoate + H2O | - |
Rattus norvegicus | 4-nitrophenol + octanoate | - |
? | |
| 4-nitrophenyl pentanoate + H2O | - |
Rattus norvegicus | 4-nitrophenol + pentanoate | - |
? | |
| 4-nitrophenyl propionate + H2O | - |
Rattus norvegicus | 4-nitrophenol + propionate | - |
? | |
| phenyl acetate + H2O | - |
Rattus norvegicus | phenol + acetate | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 56 | - |
60 min, 30-40% loss of activity | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 8.8 | - |
Rattus norvegicus |
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