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4.2.1.1: carbonic anhydrase

This is an abbreviated version!
For detailed information about carbonic anhydrase, go to the full flat file.

Word Map on EC 4.2.1.1

Reaction

H2CO3
=
CO2
 +
H2O

Synonyms

(CA) XIV, AaCA1, alkalistable alpha-carbonic anhydrase, alpha carbonic anhydrase, alpha class carbonic anhydrase, alpha-CA, alpha-carbonic anhydrase, alpha-carbonic anhydrase isozyme II, alpha-class carbonic anhydrase, alpha-type CA, alpha-type carbonic anhydrase, alphaCA, alphaCA1, Am CA, AmCA, anhydrase, ASCA, AtCA1, AtCA2, AtCAL1, AtCAL2, B13-CA, BCA II, bCA IV, BCAII, BCAIIGln253Cys, beta carbonic anhydrase, beta-CA, beta-carbonic anhydrase, beta-class carbonic anhydrase, betaCA, betaCA1, BhCA, bovine carbonic anhydrase II, bsCA I, bsCA II, CA, CA 1, CA 3, CA I, CA II, CA III, CA IV, CA IX, CA VA, CA VB, CA VI, CA VII, CA VIII, CA XII, CA XIII, CA XIV, Ca XV, CA-I, CA-II, CA-III, CA-IX, CA-VA, CA-VB, CA-VI, CA-VII, CA-XII, CA-XIV, CA1, CA14x, CA2, CA2 homolog, CA2-like, CA3, CA4, CA5A, CA6, CA9, CAA, CAA1, CAA2, Cab, cab-type beta-class carbonic anhydrase, cadmium carbonic anhydrase, CAH3, CAH7, CAH8, CAI, CAII, CAIII, CAIV, CAIX, Cam, CamH, CaN, Can2, canA, canB, CaNce103, carbonate anhydrase, Carbonate dehydratase, carbonate dehydratase I, carbonate dehydratase III, Carbonate dehydratase IX, Carbonate dehydratase VA, Carbonate dehydratase VB, Carbonate dehydratase VI, Carbonate dehydratase VII, Carbonate dehydratase XII, Carbonate dehydratase XIV, carbonate hydro-lyase, carbonate hydrolase, carbonate hydrolyase, carbonic acid anhydrase, carbonic anhydrase, carbonic anhydrase 1, carbonic anhydrase 14, carbonic anhydrase 2, carbonic anhydrase 3, carbonic anhydrase 5A, carbonic anhydrase 6, carbonic anhydrase 9, carbonic anhydrase cambialistic enzyme, carbonic anhydrase I, carbonic anhydrase I (CA I) Michigan 1, carbonic anhydrase II, carbonic anhydrase III, carbonic anhydrase isozyme I, carbonic anhydrase isozyme II, carbonic anhydrase isozyme III, carbonic anhydrase isozyme IV, carbonic anhydrase isozyme IX, carbonic anhydrase IV, carbonic anhydrase IX, carbonic anhydrase type III, carbonic anhydrase V, carbonic anhydrase VA, carbonic anhydrase VI, carbonic anhydrase VII, carbonic anhydrase XII, carbonic anhydrase XIII, carbonic anhydrase XIV, carbonic anhydrase XV, carbonic anhydrase-I, carbonic anhydrase-II, carbonic anhydrase-related protein, carbonic anhydrase-related protein VIII, carbonic dehydratase, carboxyanhydrase, CARP, CAS1, CAS2, CasCAc, CasCAg, CAV, CAVA, CAXII, CcaA, CcmM, CDCA1, chloroplast carbonic anhydrase, clCA, CmCA, CO2 hydrase, CO2 hydratase, CPB, CpsCA, CpsCAgamma, CrCAH3, CsoSCA, cynT, CynT2, cytoplasmic carbonic anhydrase, Dca, dCA I, dCA II, dCAII, DDCA, dehydratase, carbonate, delta carbonic anhydrase, delta-carbonic anhydrase, delta-class CA, diatom carbonic anhydrase, Dsp-aCAopt sp., dual domain-carbonic anhydrase, dual-domain carbonic anhydrase, DVU_1777, E84A MTCA, eCA, ECCA, erythrocyte carbonic anhydrase, eta-CA, eta-carbonic anhydrase, external carbonic anhydrase, extracellular carbonic anhydrase, FbiCA 1, fCA, gamma carbonic anhydrase 1, gamma carbonic anhydrase 2, gamma carbonic anhydrase-like 1, gamma carbonic anhydrase-like 2, gamma-CA, gamma-CA1, gamma-CA2, gamma-CAL1, gamma-CAL2, gamma-carbonic anhydrase, gamma-class carbonic anhydrase, gammaCA, H216N ATCA, H64A HCA II, HC II, HCA, hCA I, HCA II, hCA III, hCA IV, hCA IX, hCA VA, hCA VB, hCA VI, hCA VII, hCA XII, hCA XIV, hCA XIV catalytic domain, HCA-I, HCA-II, hCAII, HcCA3, HICA, HP1186, hpalphaCA, hpbetaCA, human carbonic anhydrase, human carbonic anhydrase I, human carbonic anhydrase II, human carbonic anhydrase III, human carbonic anhydrase isoenzyme I, human carbonic anhydrase isoenzyme II, human carbonic anhydrase IX, human carbonic anhydrase XII, human carbonic anhydrase XIV, Ice-CA, icfA, isozyme CA II, isozyme CA IV, LdcCA, luminal carbonic anhydrase, lwCA, mCA V, mCA XIII, Membrane antigen MN, mesohalophilic carbonic anhydrase, MG-CA, MgaCA, More, mtcA1, mtcA2, MtCam, MTCY373.03, Nce103, NcoCA, NGCA, NstCcmM209, OEC33 protein, P54/58N, pentraxin-CA VI, pentraxin-carbonic anhydrase, PERMA_1443, PF3D7_1140000, PfCAdom, PgiCA, PgiCAb, PGJ_00014320, PhaCAgamma, PhCamH, photosystem II-associated carbonic anhydrase, Pl-can, plant-type (beta-class) carbonic anhydrase, PMCA, pMW1, poly-[Hb-SOD-CAT-CA], polyhemoglobin-superoxide dismutase-catalase-carbonic anhydrase, PtCA1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250, RT erythrocyte CA, Rv1248, Rv1284, Rv3273, Rv3588c, SABP3, Salivary carbonic anhydrase, SazCA, scCA, Secreted carbonic anhydrase, secretory carbonic anhydrase, secretory carbonic anhydrase VI, SspCA, STPCA, STPCA-2, SULAZ_0541, TacA, TCAb, TCAc, TcCA, Tcru, Tcr_1545, Theam_1576, tobacco salicylic acid-binding protein 3, Tumor antigen HOM-RCC-3.1.3, TWCA1, TweCA, VchCA

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.1 carbonic anhydrase

Inhibitors

Inhibitors on EC 4.2.1.1 - carbonic anhydrase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl sulfamate
-
-
(1R,2S,3S,4S)-4,6-diamino-2-([3-O-[(1S,2S,3S,4S,5S)-2-amino-5-(aminomethyl)-3,4-dihydroxycyclohexyl]-alpha-L-arabinofuranosyl]oxy)-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-beta-L-glucopyranoside
-
i.e. neosym
(2,4,6-triisopropylphenyl)sulfonylsulfamic acid
(2,4,6-tripropylphenyl)sulfonylsulfamic acid
(2,5-dichlorophenyl)sulfonylsulfamic acid
(2-nitrophenyl)sulfonylsulfamic acid
(2E)-2-[(4-hydroxy-3-methylphenyl)methylidene]-N-(5-sulfanylidene-4,5-dihydro-1,3,4-thiadiazol-2-yl)hydrazine-1-carboxamide
-
(2E)-2-[(4-hydroxyphenyl)methylidene]-N-(5-sulfanylidene-4,5-dihydro-1,3,4-thiadiazol-2-yl)hydrazine-1-carboxamide
-
(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid
-
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
-
(2E)-4-methoxy-4-oxobut-2-enoic acid
-
-
(2E)-but-2-enedioic acid
-
-
(2R)-3-(3-chloro-4-hydroxyphenyl)-2-[[(2E)-4-methoxy-4-oxobut-2-enoyl]amino]propanoic acid
-
-
(2S)-3-(3-chloro-4-hydroxyphenyl)-2-[[(2E)-4-methoxy-4-oxobut-2-enoyl]amino]propanoic acid
-
-
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
-
i.e. penokain G
-
(2Z)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
(2Z)-2-(3-bromobenzylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
(2Z)-2-(3-methoxybenzylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
(2Z)-2-(4-chlorobenzylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
(2Z)-2-(4-fluorobenzylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
-
-
(2Z)-2-(4-methylpentan-2-ylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
(2Z)-2-benzylidene-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
(3,5-dichloro-2-hydroxyphenyl)sulfonylsulfamic acid
(3-chloro-4-hydroxyphenyl)acetic acid
-
-
(3-chloro-4-nitrophenyl)sulfonylsulfamic acid
(3-chlorophenyl)(2-thioxo-1H-benzo[d]imidazol-1-yl)methanone
-
-
(3-chlorophenyl)acetic acid
-
-
(3-nitrophenyl)sulfonylsulfamic acid
(3aR,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl sulfamate
-
-
(4-acetylphenyl)sulfonylsulfamic acid
(4-bromophenyl)sulfonylsulfamic acid
(4-chlorophenyl)sulfonylsulfamic acid
(4-fluorophenyl)sulfonylsulfamic acid
(4-hydroxyphenyl)acetic acid
-
-
(4-iodophenyl)sulfonylsulfamic acid
(4-methoxyphenyl)sulfonylsulfamic acid
(4-methylphenyl)sulfonylsulfamic acid
(4-nitrophenyl)sulfonylsulfamic acid
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~-thieno[3,2-e][1,2]thiazine-6-sulfonamide
-
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
(4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda~6~-thieno[2,3-b]thiopyran-2-sulfonamide
-
(5Z)-2-amino-5-(3,4-dihydroxybenzylidene)-3,5-dihydro-4H-imidazol-4-one
-
-
(5Z)-2-amino-5-(4-hydroxy-3-methoxybenzylidene)-3,5-dihydro-4H-imidazol-4-one
-
-
(6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
-
-
(7S)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino]-3-[[(furan-2-carbonyl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
-
i.e. ceftiofur
(E)-3-phenyl-1-(2-thioxobenzo[d]oxazol-3(2H)-yl)prop-2-en-1-one
-
36% inhibition
(heptadecafluorooctyl)sulfonylsulfamic acid
(nonafluorobutyl)sulfonylsulfamic acid
(pentafluorophenyl)sulfonylsulfamic acid
(R)- 4-(2-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)- 4-(4-benzoyl-2-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-1-[4-(benzenesulfonyl)-2-benzylpiperazin-1-yl]ethan-1-one
-
(R)-17(R)-4-[2-benzyl-4-(4-sulfamoylbenzoyl)piperazine-1-carbonyl]benzene-1-sulfonamide
-
(R)-4-(2,4-dibenzylpiperazine-1-carbonyl)benzenesulfonamide
-
(R)-4-(2-benzyl-4-methanesulfonylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-(2-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-(3,4-dibenzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-(3-benzyl-4-methanesulfonylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-(3-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-(3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-(4-acetyl-3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-(4-benzoyl-2-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-(4-benzoyl-3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(R)-4-[2-benzyl-4-(2-phenylacetyl)piperazine-1-carbonyl]benzene-1-sulfonamide
-
(R)-4-[3-benzyl-4-(2-phenylacetyl)piperazine-1-carbonyl]benzene-1-sulfonamide
-
(R)-4-[4-(benzenesulfonyl)-2-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
-
(R)-4-[4-(benzenesulfonyl)-3-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
-
(S)- 4-(2-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)- 4-(4-benzoyl-2-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-1-[4-(benzenesulfonyl)-2-benzylpiperazin-1-yl]ethan-1-one
-
(S)-2-(2-ammoniopropanamido)-4-methylbenzo[d]thiazol-3-ium di-2,2,2-trifluoroacetate
-
(S)-4-(2,4-dibenzylpiperazine-1-carbonyl)benzenesulfonamide
-
(S)-4-(2-benzyl-4-methanesulfonylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-(2-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-(3,4-dibenzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-(3-benzyl-4-methanesulfonylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-(3-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-(3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-(4-acetyl-3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-(4-benzoyl-2-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-(4-benzoyl-3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
-
(S)-4-[2-benzyl-4-(2-phenylacetyl)piperazine-1-carbonyl]benzene-1-sulfonamide
-
(S)-4-[2-benzyl-4-(4-sulfamoylbenzoyl)piperazine-1-carbonyl]benzene-1-sulfonamide
-
(S)-4-[3-benzyl-4-(2-phenylacetyl)piperazine-1-carbonyl]benzene-1-sulfonamide
-
(S)-4-[4-(benzenesulfonyl)-2-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
-
(S)-4-[4-(benzenesulfonyl)-3-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
-
(S)-benzyl (1-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-1-oxopropan-2-yl)carbamate
-
(S)-benzyl (1-((4-methylbenzo[d]thiazol-2-yl)amino)-1-oxopropan-2-yl)carbamate
-
(S)-tert-butyl (1-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
-
(S)-tert-butyl (1-((4-methylbenzo[d]thiazol-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
-
(S)-tert-butyl (1-((4-methylbenzo[d]thiazol-2-yl)amino)-1-oxopropan-2-yl)carbamate
-
(S)-tert-butyl (1-((6-(methylsulfonyl)benzo[d]thiazol-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
-
(trichloromethyl)sulfonylsulfamic acid
(trifluoromethyl)sulfonylsulfamic acid
1,1'-(tribromo-lambda5-stibanediyl)bis(2-aminopyridin-1-ium)
1,1'-(tribromo-lambda5-stibanediyl)bis(2-aminopyrimidin-1-ium)
1,1'-(trichloro-lambda5-stibanediyl)bis(2-amino-4,6-dimethoxy-5-sulfanylpyrimidin-1-ium)
1,1'-(trichloro-lambda5-stibanediyl)bis(2-aminopyridin-1-ium)
1,1'-(trichloro-lambda5-stibanediyl)bis(2-aminopyrimidin-1-ium)
1,1'-(trichloro-lambda5-stibanediyl)bis[2-amino-4,6-dimethoxy-5-[(1H-tetrazol-5-yl)sulfanyl]pyrimidin-1-ium]
14.3% inhibition of CO2 hydration reaction after 30 min
1,1,1-trifluoromethanesulfonamide
-
1,1,2,2,3,3,4,4 octafluoro-n-butane-1-4-bissulfonamide
-
-
1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-n-hexane-1-sulfonamide
1,1,2,2,3,3,4,4,5,5,6,6,7,7,7-pentadecafluoro-n-heptane-1-sulfonamide
1,1,2,2,3,3,4,4-octafluoro-n-butane-1-4-bissulfonamide
-
-
1,1-dimethyl-4-(7-sulfamoyl-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazol-3-yl)piperazin-1-ium iodide
-
1,2,4-trimethoxybenzene
-
-
1,2-benzothiazol-3(2H)-one 1,1-dioxide
1,2-bis[(2,4-dichloro-5-sulfonamidobenzamide)ethoxy]ethane
-
-
1,2-bis[(2,4-dichloro-5-sulfonamidobenzoate)-ethoxy]ethane
-
-
1,2-bis[(4-sulfonamidobenzamide)ethoxy]ethane
-
-
1,2-bis[(4-sulfonamidobenzoate)ethoxy]ethane
-
-
1,2-dimethoxybenzene
-
-
1,2:3,4-di-O-isopropylidene-alpha-D-galactopyranose 6-sulfamate
-
-
1,2:5,6-di-O-isopropylidene-alpha-D-glucofuranose 3-sulfamate
-
-
1,3-benzoxazole-2(3H)-thione
-
-
1,3-diacetyl-1H-benzo[d]imidazol-2(3H)-one
-
10% inhibition
1,3-diacetylbenzimidazole-2-thione
-
-
1,3-dihydro-2H-benzimidazole-2-thione
-
-
1,3-dimethylpyrimidine-2,4(1H,3H)-dione
inhibition of isozyme hCA I; inhibition of isozyme hCA II
1,3-dioxolan-2-yl-N-(2-propenyl)-2-thiophene-sulfonamide
-
-
1,4-dimethoxybenzene
-
-
1,5-bis[amino(dihydroxy)-lambda4-sulfanyl]-2,3-dichlorobenzene
1-(1,2-benzoxazol-3-yl)methanesulfonamide
1-(2-thioxo-1H-benzo[d]imidazol-1-yl)-3-phenylpropan-1-one
-
-
1-(2-thioxo-1H-benzo[d]imidazol-1-yl)ethanone
-
-
1-(2-thioxo-1H-benzo[d]imidazol-1-yl)hexan-1-one
-
-
1-(2-thioxo-1H-benzo[d]imidazol-1-yl)propan-1one
-
-
1-(2-thioxobenzo[d]oxazol-3(2H)-yl)decan-1-one
-
-
1-(2-thioxobenzo[d]oxazol-3(2H)-yl)ethanone
-
-
1-(2-thioxobenzo[d]oxazol-3(2H)-yl)hexadecan-1-one
-
-
1-(2-thioxobenzo[d]oxazol-3(2H)-yl)hexan-1-one
-
-
1-(2-thioxobenzo[d]oxazol-3(2H)-yl)propan-1-one
-
-
1-(2-Tthioxo-1H-benzo[d]imidazol-1-yl)butan-1-one
-
-
1-(3-acetyl-1,2-dihydro-2-thioxobenzo[d]imidazol-1-yl)hexan-1-one
-
-
1-(3-ethyl-1,2-dihydro-2-thioxobenzo[d]imidazole-1-yl)ethanone
-
-
1-(4-methoxyphenyl)-2-methyl-3-nitro-1-H-indol-6-ol
ID-8; ID-8
1-cyclohexyl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
1-cyclopentyl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
1-cyclopropyl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
1-ethyl-1H-benzo[d]imidazole-2(3H)-thione
-
28% inhibition
1-n-butyl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
1-naphthylsulfonylsulfamic acid
1-[(2-oxo-2H-chromen-6-yl)methyl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane
-
1-[(aminooxy)sulfinyl]-4-methylbenzene
-
-
1-[2-(1H-imidazol-5-yl)ethyl]-4-methyl-2,6-di(propan-2-yl)pyridin-1-ium hexafluorophosphate
-
1-[4-[(aminooxy)sulfinyl]phenyl]methanamine
-
-
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]ethanamine
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]methanamine
12,12,12-tribromo-7-oxo-6,7a,8,9,10,12-hexahydro-7H-12lambda5-pyrrolo[1',2':1,7][1,3,5,2]triazastibepino[4,3-b][1,3]benzothiazol-13-ium
1H,1H,2H,2H-perfluorodecyl sulfamate
-
-
1H,1H,2H,2H-perfluorooctyl sulfamate
-
-
1H,1H-perfluoroethyl sulfamate
-
-
1H-perfluoroisopropyl sulfamate
-
-
2,2,2-trifluoro-N-(4-sulfamoylphenyl)acetamide
-
-
2,3,4,5,6-pentafluoro-N-(2-sulfamoylphenyl)benzenesulfonamide
-
-
2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)benzamide
-
-
2,3,4,5,6-pentafluoro-N-[(2E)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]benzamide
-
-
2,3,4,6-tetra-O-acetyl-N-sulfamoyl-beta-D-galactopyranosylamine
-
-
2,3,4,6-tetra-O-acetyl-N-sulfamoyl-beta-D-glucopyranosylamine
-
-
2,3,4,6-tetra-O-acetyl-N-sulfamoyl-beta-D-mannopyranosylamine
-
-
2,3,4-tri-O-acetyl-6-deoxy-N-sulfamoyl-alpha-L-glucopyranosylamine
-
-
2,3,5,6-tetrafluoro-4-(2-phenylethanesulfonyl)benzene-1-sulfonamide
-
2,3,6-trifluoro-4-(2-hydroxyethanesulfonyl)-5-[[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino]benzene-1-sulfonamide
-
2,4,6-trichlorophenyl sulfamate
-
-
2,4-bis[(aminooxy)sulfinyl]-5-(trifluoromethyl)aniline
-
-
2,4-bis[(aminooxy)sulfinyl]-5-chloroaniline
-
-
2,4-bis[amino(dihydroxy)-lamba4-sulfanyl]-5-(trifluoromethyl)aniline
2,4-bis[amino(dihydroxy)-lambda4-sulfanyl]-5-chloroaniline
2,4-Dichlorophenol
-
-
2,5-difluorophenol
-
-
2,6-dimethoxybenzoic acid
-
-
2,6-PDCA
Halalkalibacterium halodurans
-
2-(1-methylethyl)-3-[(2-propynylamino)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-(1-methylethyl)-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-(2,2-dichloroacetylamino)-1,3,4-thiadiazole-5-sulfonamide
-
noncompetitive inhibition
2-(2-hydroxyethyl)-N-(1,1-dimethylethyl)-2H-thieno[3,2-e-]-1,2-thiazine-6-sulfonamide 1,1-dioxide
-
-
2-(2-methoxyethyl)-3-[(4-morpholinyl)methyl]-2-(2-propenyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-(2-methoxyethyl)-3-[[bis(2-methoxyethyl)amino]methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-(3,4-dimethoxyphenyl)-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-(3-chloro-4-hydroxyphenyl)-N-(2-methoxyethyl)acetamide
-
-
2-(3-chloro-4-hydroxyphenyl)-N-(2-phenylethyl)acetamide
-
-
2-(3-chloro-4-hydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
-
-
2-(3-chloro-4-hydroxyphenyl)-N-[2-(3-methoxyphenyl)ethyl]acetamide
-
-
2-(3-chloro-4-hydroxyphenyl)-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
-
-
2-(3-chloro-4-hydroxyphenyl)acetamide
-
-
2-(3-chloropropionylamino)-1,3,4-thiadiazole-5-sulfonamide
-
noncompetitive inhibition
2-(3-hydroxyphenyl)-3-(4-morpholinylmethyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-(3-hydroxyphenyl)-3-[(2-propynylamino)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-(3-hydroxyphenyl)ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
-
2-(3-hydroxyphenyl)ethyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate
-
2-(3-hydroxypropyl)-3-(4-morpholinylmethyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-(3-methoxyphenyl)-3-[(2-hydroxyethylamino)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-(3-methoxyphenyl)-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-(3-methoxypropyl)-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-(3-methoxypropyl)-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-(3-methoxypropyl)-4-(methylamino)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
2-(3-phenylpropionylamino)-1,3,4-thiadiazole-5-sulfonamide
-
noncompetitive inhibition
2-(4-hydroxyphenyl)acetamide
-
-
2-(4-hydroxyphenyl)ethyl (2E)-3-(3-hydroperoxy-4-hydroxyphenyl)prop-2-enoate
-
2-(4-hydroxyphenyl)ethyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate
-
2-(7-methoxy-2-oxo-2H-chromen-4-yl)-N-(2-sulfamoylphenyl)acetamide
-
-
2-(7-methoxy-2-oxo-2H-chromen-4-yl)-N-(3-sulfamoylphenyl)acetamide
-
-
2-(7-methoxy-2-oxo-2H-chromen-4-yl)-N-(4-sulfamoylphenyl)acetamide
-
-
2-(benzenesulfonamido-N-benzyl)-5-[N,Ndibenzylsulfonamido]-l,3,4-thiadiazole
-
-
2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide
2-(hydroxymethyl)-4-nitro-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide
-
2-(hydroxymethyl)-4-nitro-N-[2-(4-sulfamoylphenyl)ethyl]benzenesulfonamide
2-(p-toluenesulfonamido)-l,3,4-thiadiazole-5-sulfonamide
-
-
2-(phenylethynyl)benzenesulfonamide
-
-
2-acetylamido-1,3,4-thiadiazole-5-sulfonamide
-
acetazolamide
2-adamantylethyl 7-methoxy-2-oxo-2H-chromene-8-carboxylate
-
-
2-amino-1-benzothiophen-3(2H)-one 1,1-dioxide
-
-
2-amino-pyrimidin-4-yl-sulfanilamide
-
best inhibitor
2-aminobenzenesulfonamide
2-benzene-sulfonamido-l,3,4-thiadiazole-5-sulfonamide
-
-
2-bromo-benzene sulfonamide
-
-
2-bromo-benzenesulfonamide
-
-
2-bromobenzene-1-sulfonamide
-
-
2-coumaric acid
-
2-cyclohexyl-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-cyclopropylmethyl-3-[(4-morpholinyl)methyl]-2-(2-propenyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-ethyl-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-ethyl-3-[[bis(2-hydroxyethyl)amino]methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-ethyl-3-[[bis(2-methoxyethyl)amino]methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-hydrazinobenzenesulfonamide
2-hydrazinylbenzenesulfonamide
2-hydroxycinnamic acid
-
-
2-mercaptoethanol
2-methoxy-N-[(1-methylpyrrolidin-2-yl)methyl]-5-sulfamoylbenzamide
2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-methanol 1,1-dioxide
-
-
2-methyl-2H-thieno[3,2-e]-1,2-thiazine-3-methanol 1,1-dioxide
-
-
2-methyl-3-(4-morpholinylmethyl)-2H-thieno[2,3-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
-
-
2-methyl-3-(4-morpholinylmethyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-methyl-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-methyl-3-[[N-(2-methoxyethyl)-N-(2-propenyl)amino]methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-methyl-3-[[N-(2-methoxyethyl)-N-(3-methoxypropyl)-amino]methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-methyl-N-(4-sulfamoylphenyl)propanamide
-
-
2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide
2-N-(4-sulfamoylphenyl)-thioformyl-L-Ala
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Asn
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Gln
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Ile
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Leu
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Met
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Phe
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Pro
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Trp
-
-
2-N-(4-sulfamoylphenyl)-thioformyl-L-Val
-
-
2-naphthyl sulfamate
-
-
2-naphthylsulfamate
-
-
2-naphthylsulfonylsulfamic acid
2-nitrobenzenesulfonamide
-
-
2-Nitrophenol
-
product inhibition
2-oxo-2H-chromene-3-carboxylic acid
-
2-oxo-2H-thiochromene-3-carboxylic acid
-
2-oxo-N-(2-sulfamoylphenyl)-2H-chromene-3-carboxamide
-
-
2-oxo-N-(3-sulfamoylphenyl)-2H-chromene-3-carboxamide
-
-
2-oxo-N-(4-sulfamoylbenzyl)-2H-chromene-3-carboxamide
-
-
2-oxo-N-(4-sulfamoylphenyl)-2H-chromene-3-carboxamide
-
-
2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2H-chromene-3-carboxamide
-
-
2-phenoxy-1-(2-thioxobenzo[d]oxazol-3(2H)-yl)ethanone
-
-
2-phenyl-1-(2-thioxobenzo[d]oxazol-3(2H)-yl)ethanone
-
-
2-phenylethyl sulfamate
-
-
2-propyl-3-[(2-propynylamino)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-sulfonamido-1,3,4-thiadiazole-5-benzene sulfonamide
-
-
2-[(4-methoxyphenyl)methyl]-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
2-[(4-methoxyphenyl)methyl]-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-[(4-morpholinyl)phenyl]-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
2-[(aminooxy)sulfinyl]-5-(2-chlorophenyl)-1,3,4-thiadiazole
-
-
2-[(aminooxy)sulfinyl]aniline
-
-
2-[(diphenylcarbamoyl)amino]benzenesulfonamide
-
-
2-[(p-toluenesulfonamido)-N-methyl]-5-[N,N-dimethylsulfonamide]-l,3,4-thiadiazole
-
-
2-[2-(4-morpholinyl)ethyl]-2H-thieno[3,2-e-]-1,2-thiazine-6-sulfonamide 1,1-dioxide hydrochloride
-
-
2-[2-(acetoxy)ethyl]-N-(1,1-dimethylethyl)-4-hydroxy-2H-thieno[3,2-e-]-1,2-thiazine-6-sulfonamide 1,1-dioxide
-
-
2-[2-(propylamino)ethyl]-2H-thieno[3,2-e-]-1,2-thiazine-6-sulfonamide 1,1-dioxide hydrochloride
-
-
2-[2-[4-acetyl-(1-piperazinyl)]ethyl]-2H-thieno[3,2-e-]-1,2-thiazine-6-sulfonamide 1,1-dioxide
-
-
2-[2-[bis(2-methoxyethyl)amino]ethyl]-2H-thieno[3,2-e-]-1,2-thiazine-6-sulfonamide 1,1-dioxide hydrochloride
-
-
2-[3-[2-(3-hydroxyphenyl)ethoxy]phenyl]ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
-
2-[4-(4-morpholinyl)-2-butenyl]-2H-thieno[3,2-e-]-1,2-thiazine-6-sulfonamide 1,1-dioxide hydrochloride
-
-
2-[4-[(aminooxy)sulfinyl]phenyl]ethanamine
-
-
2-[4-[(aminooxy)sulfinyl]phenyl]ethanol
-
-
2-[4-[2-(4-hydroxyphenyl)ethoxy]phenyl]ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
-
2-[benzenesulfonamido-N-(n-propyl)]-l,3,4-thiadiazole-5-sulfonamide
-
-
2-[[(5-chlorothiophen-2-yl)(hydroxy)methyl]amino]-1-(trichloro[2-[2-(5-chlorothiophen-2-yl)-2-oxoethyl]pyrimidin-1-ium-1-yl]-lambda5-stibanyl)pyrimidin-1-ium
2H-chromen-2-one
-
3,3,4,4,5,5,6,6,6-nonafluoro-n-hexanesulfonamide
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-n-octanesulfonamide
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-n-decanesulfonamide
3,3-dimethyl-N-(4-sulfamoylphenyl)butanamide
-
-
3,4,6-tri-O-acetyl-2-deoxy-N-sulfamoyl-beta-D-arabino-hexopyranosylamine
-
-
3,4,6-tri-O-acetyl-2-deoxy-N-sulfamoyl-beta-D-lyxo-hexopyranosylamine
-
-
3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
3,4-dihydroxybenzoic acid
-
-
3,4-dimethoxybenzoic acid
-
-
3,5-dibromo-2-(1,3-dioxalan-2-yl)-thiophene
-
-
3,5-dichloro-2-hydroxybenzene-1-sulfonamide
-
3,5-dichloro-2-hydroxybenzenesulfonamide
3,5-difluorophenol
-
-
3,5-Dihydroxybenzoic acid
-
-
3-(1,3-dioxolan-2-yl)-N-(2-methoxyethyl)-2-thiophenesulfonamide
-
-
3-(1,3-dioxolan-2-yl)-N-(3,4-dimethoxyphenyl)-2-thiophenesulfonamide
-
-
3-(1,3-dioxolan-2-yl)-N-(3-methoxyphenyl)-2-thiophenesulfonamide
-
-
3-(1,3-dioxolan-2-yl)-N-(4-(4-morpholinyl)phenyl)-2-thiophenesulfonamide
-
-
3-(1,3-dioxolan-2-yl)-N-cyclohexyl-2-thiophenesulfonamide
-
-
3-(1,3-dioxolan-2-yl)-N-[4-(4-morpholinyl)phenyl]-2-thiophenesulfonamide
-
-
3-(4-methylpiperazin-1-yl)-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
-
3-(4-sulfamoylphenyl)propanoic acid
3-(benzylamino)-2,5,6-trifluoro-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide
-
3-(methylsulfanyl)-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
-
3-(methylsulfonyl)-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
-
3-(phenylethynyl)benzenesulfonamide
-
-
3-(phenylsulfanyl)-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
-
3-3-(1,3-dioxolan-2-yl)-N-(1-methylethyl)-2-thiophene-sulfonamide
-
-
3-acetylbenzo[d]oxazol-2(3H)-one
-
-
3-amino-1,1,1-tribromo-4,5-dihydro-1H-1lambda5-[1,3,5,2]triazastibinino[1,6-a]benzimidazol-10-ium
35% inhibition of CO2 hydration reaction after 30 min
3-amino-1,1,1-trichloro-4,5-dihydro-1H-1lambda5-[1,3,5,2]triazastibinino[1,6-a]benzimidazol-10-ium
10.0% inhibition of CO2 hydration reaction after 30 min
3-aminobenzene-1-sulfonamide
-
3-aminobenzenesulfonamide
3-bromo-4-amino-benzenesulfonamide
-
-
3-bromosulfanilamide
-
-
3-chloro-4-amino-benzenesulfonamide
-
-
3-chloro-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
-
3-chloromethyl-N-(1,1-dimethylethyl)-2-(3-methoxyphenyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
3-chloropropyl sulfamate
-
-
3-cyclohexyl-1-(2-thioxobenzo[d]oxazol-3(2H)-yl)propan-1-one
-
-
3-ethylbenzo[d]oxazole-2(3H)-thione
-
17% inhibition
3-fluoro-4-amino-benzenesulfonamide
-
-
3-hexanoylbenzo[d]oxazol-2(3H)-one
-
-
3-Hydroxybenzoic acid
-
-
3-hydroxymethyl 2-methyl-2H-thieno[2,3-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
-
-
3-hydroxymethyl-2-methyl-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
-
-
3-iodo-4-amino-benzenesulfonamide
-
-
3-methylphenylsulfamate
-
-
3-methylsalicylic acid
-
noncompetitive inhibition of isozyme carbonic anhydrase I and uncompetitive inhibition of isozyme carbonic anhydrase II
3-morpholin-4-yl-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
-
3-phenyl-1-(2-thioxobenzo[d]oxazol-3(2H)-yl)propan-1-one
-
-
3-phenylprop-2-ene-1-sulfonamide
-
-
3-phenylpropanenitrile
-
-
3-tributylgermylpropanamine
-
-
3-triethylgermylpropanamine
-
-
3-triethylsilylpropanamine
-
-
3-triphenylgermylpropanamine
-
-
3-[(1-imidazolyl)methyl]-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
3-[(3-fluorophenyl)ethynyl]benzenesulfonamide
-
-
3-[(3-methoxyphenyl)ethynyl]benzenesulfonamide
-
-
3-[(4-methylphenyl)ethynyl]benzenesulfonamide
-
-
3-[(4-morpholinyl)methyl]-2-(2-propenyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
3-[(4-morpholinyl)methyl]-2-propyl-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
3-[(anilinocarbonyl)amino]benzenesulfonamide
3-[(cyclopropylamino)methyl]-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
3-[(phenylcarbamoyl)amino]benzenesulfonamide
-
-
3-[(sulfoamino)sulfonyl]benzoic acid
3-[1,3-dioxolan-2-yl]-N-(2-methoxyethyl)-2-thiophenesulfonamide
-
-
3-[1,3-dioxolan-2-yl]-N-(3,4-dimethoxyphenyl)-2-thiophenesulfonamide
-
-
3-[4-[(aminooxy)sulfinyl]phenyl]propanoic acid
-
-
3-[9-borabicyclo[1.3.3.]nonane]-1-bromopropane
-
-
3-[9-borabicyclo[1.3.3.]nonane]-1-propylsulfonic acid sodium salt
-
-
3-[amino(dihydroxy)-lambda4-sulfanyl]aniline
3-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-2,5,6-trifluoro-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide
-
3-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-2,5,6-trifluoro-4-(2-phenylethanesulfonyl)benzene-1-sulfonamide
-
3-[[(3,4-dimethoxyphenyl)methyl]amino]-2,5,6-trifluoro-4-(2-hydroxyethanesulfonyl)benzene-1-sulfonamide
-
3-[[(aminosulfonyl)amino]sulfonyl]benzoic acid
3-[[bis(2-methoxyethyl)amino]methyl]-2-propyl-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
3-[[N-(2-methoxyethyl)-N-(2-propenyl)amino]methyl]-2-methyl-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
3-[[N-(2-methoxyethyl)-N-(3-methoxypropyl)amino]methyl]-2-methyl-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide hydrochloride
-
-
3-[[N-(2-methoxyethyl)-N-methylamino]methyl]-2-methyl-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
3alpha,12alpha-diacetoxy-5beta-cholan-24-oic acid
-
-
3alpha,7alpha,12alpha-triacetoxy-5beta-cholan-24-oic acid
-
-
3alpha-acetoxy-5beta-cholan-24-oic acid
-
-
4,4'-thiodipyridine-3-sulfonamide
-
-
4,4'-[(1R,2R,3S,4S)-3,4-dimethylcyclobutane-1,2-diyl]bis(2-methoxyphenol)
-
-
4,4'-[(1R,2S,3R,4S)-3,4-dimethylcyclobutane-1,2-diyl]bis(2-methoxyphenol)
-
-
4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol)
-
-
4,5-dichloro-benzene-1,3-disulfonamide
4,5-dichlorobenzene-1,3-disulfonamide
4,6-dinitrosalicylic acid
-
noncompetitive inhibition of isozymes carbonic anhydrase I and II
4-(1,1-dioxido-1,2-thiazinan-2-yl)benzenesulfonamide
4-(1,1-dioxo-1lambda6,2-thiazinan-2-yl)benzene-1-sulfonamide
-
4-(1,3,4-thiadiazol-2-ylthio)pyridine-3-sulfonamide
-
-
4-(1-methyl-5-tetrazolylthio)pyridine-3-sulfonamide
-
-
4-(2-([(4-sulfamoylphenyl)carbamothioyl]amino)ethyl)benzenesulfonamide
-
-
4-(2-amino-pyrimidin-4-yl)-benzenesulfonamide
4-(2-aminoethyl) benzenesulfonamide
-
-
4-(2-aminoethyl)benzene-1-sulfonamide
-
4-(2-aminoethyl)benzenesulfonamide
4-(2-hydroxyethyl)benzene-1-sulfonamide
-
4-(2-hydroxyethyl)benzenesulfonamide
4-(2-hydroxyethyl)phenol
-
-
4-(2-methyl-8-quinolinoxy)-3-pyridinesulfonamide
-
-
4-(2-methylphenyl)benzene-1-sulfonamide
-
4-(2-phenylacetamido)-3-bromobenzenesulfonamide
4-(2-phenylacetamido)-3-chlorobenzenesulfonamide
4-(2-phenylacetamido)-3-fluorobenzenesulfonamide
4-(2-phenylacetamido)benzenesulfonamide
4-(2-phenylacetamidoethyl)benzenesulfonamide
4-(2-phenylacetamidomethyl)benzenesulfonamide
4-(2-propynylthio)pyridine-3-sulfonamide
-
-
4-(2-pyridin-2-ylacetamido)benzenesulfonamide
4-(2-pyridin-4-ylacetamido)benzenesulfonamide
4-(2-pyridin-4-ylacetamidoethyl)benzenesulfonamide
4-(2-[(phenylcarbamothioyl)amino]ethyl)benzenesulfonamide
-
-
4-(2-[(phenylcarbamoyl)amino]ethyl)benzenesulfonamide
-
-
4-(3,4-dichlorophenylureido)thioureido-benzenesulfonamide
-
effective in vitro carbonic anhydrase inhibitor
4-(3-formylphenyl)benzene-1-sulfonamide
-
4-(3-quinolinyl)benzene-1-sulfonamide
-
4-(3-[[(1E)-(1-methyl-1H-imidazol-2-yl)methylidene]amino]propyl)benzenesulfonamide
-
-
4-(4'-dimethylaminophenyl)diazenylbenzenesulfonamide
-
-
4-(4'-hydroxyphenyl)diazenylbenzene-N,N-dimethylsulfonamide
-
-
4-(4'-hydroxyphenyl)diazenylbenzene-N-methylsulfonamide
-
-
4-(4'-hydroxyphenyl)diazenylbenzenesulfonamide
-
-
4-(4'-methoxyphenyl)diazenylbenzene-N,N-dimethylsulfonamide
-
-
4-(4-cyanophenoxy)-3-pyridinesulfonamide
-
-
4-(4-fluorophenoxy)-3-pyridinesulfonamide
-
-
4-(4-sulfanilyl-aminoethyl)-benzenesulfonamide
-
-
4-(4-sulfanilyl-aminomethyl)-benzenesulfonamide
-
-
4-(5-methyl-2-pyrazolino)-3-pyridinesulfonamide
-
-
4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide
-
4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide
4-(6-nitrobenzothiazol-2-ylthio)pyridine-3-sulfonamide
-
-
4-(allylamino)-3-pyridinesulfonamide
-
-
4-(aminomethyl)benzene-1-sulfonamide
-
4-(aminomethyl)benzenesulfonamide
4-(aminosulfonyl)-N-[2-[4-(aminosulfonyl)phenyl]ethyl]benzamide
4-(aminosulfonyl)-N-{2-[4-(aminosulfonyl)phenyl]ethyl}benzamide
-
4-(aminosulfonyl)benzoic acid
4-(carbamothioylamino)benzenesulfonamide
-
-
4-(carbamoylmethylthio)pyridine-3-sulfonamide
-
-
4-(carboxyethyl)-benzenesulfonamide
-
-
4-(cyanomethylthio)pyridine-3-sulfonamide
-
-
4-(ethylamino)-6-(3-methoxypropyl)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
-
-
4-(hydroxymethyl)benzene-1-sulfonamide
-
4-(hydroxymethyl)benzenesulfonamide
4-(methylhydrazino)-3-pyridinesulfonamide
-
-
4-(N-oxide-2-pyridylthio)pyridine-3-sulfonamide
-
-
4-(phenylethynyl)benzenesulfonamide
-
-
4-(quinolinoxy)-3-pyridinesulfonamide
-
-
4-([(1E)-[4-(dimethylamino)phenyl]methylidene]amino)benzenesulfonamide
-
-
4-([(phenylcarbamothioyl)amino]methyl)benzenesulfonamide
-
-
4-([[(1Z)-(2-chlorophenyl)methylidene]amino]methyl)benzenesulfonamide
-
-
4-([[(diethyl-l5-azanylidyne)methyl]disulfanyl]amino)benzenesulfonamide
-
-
4-acetyl-N-(aminosulfonyl)benzenesulfonamide
4-acetylamidophenyl sulfamate
-
-
4-amino-3,5-dibromobenzenesulfonamide
4-amino-3,5-diiodobenzenesulfonamide
4-amino-3,bromobenzenesulfonamide
-
-
4-amino-3-bromobenzene-1-sulfonamide
-
4-amino-3-bromobenzenesulfonamide
4-amino-3-chlorobenzene-1-sulfonamide
-
4-amino-3-chlorobenzenesulfonamide
4-amino-3-fluoro-5-iodobenzenesulfonamide
-
4-amino-3-fluorobenzene-1-sulfonamide
-
4-amino-3-fluorobenzenesulfonamide
4-amino-3-iodobenzenesulfonamide
4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
4-amino-6-chloro-1-3 benzenedisulfonamide
-
-
4-amino-6-chloro-benzene-1,3-disulfonamide
-
-
4-amino-6-chlorobenzene-1,3-disulfonamide
4-amino-6-trifluoromethyl-benzene-1,3-disulfonamide
-
-
4-amino-benzenesulfonamide
-
-
4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzene-1-sulfonamide
-
-
4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide
4-amino-N-(4-sulfamoylcyclopenta-1,3-dien-1-yl)benzene-1-sulfonamide
-
4-amino-N-(4-sulfamoylphenyl)benzene-1-sulfonamide
-
4-amino-N-(4-sulfamoylphenyl)benzenesulfonamide
4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide
-
-
4-amino-N-carbamimidoylbenzene-1-sulfonamide
-
-
4-amino-N-[(4-sulfamoylphenyl)methyl]benzene-1-sulfonamide
-
-
4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide
-
4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzenesulfonamide
4-amino-N-[4-(aminosulfonyl)benzyl]benzenesulfonamide
4-amino-N-[4-[(aminooxy)sulfinyl]benzyl]benzenesulfonamide
-
-
4-amino-N-{2-[4-(aminosulfonyl)phenyl]ethyl}benzenesulfonamide
4-aminobenzene-1-sulfonamide
-
4-Aminobenzenesulfonamide
4-aminoethyl-benzenesulfonamide
4-aminoethylbenzenesulfonamide
-
4-aminomethyl-benzenesulfonamide
-
-
4-Aminophenol
-
-
4-aminosalicylic acid
-
noncompetitive inhibition of isozymes carbonic anhydrase I and II
4-benzythiopyridine-3-sulfonamide
-
-
4-bromo-5-(1,3-dioxalan-2-yl)-N-(1,1-dimethylethyl)-thiophene-2-sulfonamide
-
-
4-bromobenzenesulfonamide
4-bromophenyl sulfamate
4-carboxy-benzenesulfonamide
-
-
4-chloro-6-[(phenylcarbamoyl)amino]benzene-1,3-disulfonamide
-
-
4-chlorobenzene sulfonamide
-
-
4-chlorobenzene-1-sulfonamide
-
-
4-chlorobenzenesulfonamide
-
-
4-chlorophenyl sulfamate
4-cyanophenyl sulfamate
-
-
4-ethoxy-3-pyridinesulfonamide
-
-
4-ethynylbenzenesulfonamide
-
-
4-fluorobenzenesulfonamide
-
4-hydrazino-3-pyridinesulfonamide
-
-
4-hydrazinobenzenesulfonamide
4-hydrazinylbenzenesulfonamide
4-hydroxybenzene-1-sulfonamide
-
4-hydroxybenzenesulfonamide
4-hydroxybenzoic acid
-
-
4-Hydroxybenzonitrile
-
-
4-hydroxyethyl-benzenesulfonamide
-
-
4-hydroxymethyl-benzenesulfonamide
-
-
4-iodobenzenesulfonamide
4-iodophenyl sulfamate
-
-
4-methoxy-3-pyridinesulfonamide
-
-
4-methoxyphenyl sulfamate
-
-
4-methyl-5-imino-1,3,4-thiadiazoline-2-sulfonamide
-
-
4-methyl-benzenesulfonamide
-
-
4-methylbenzene-1-sulfonamide
4-methylbenzenesulfonamide
4-methylphenyl sulfamate
-
-
4-methylthiopyridine-3-sulfonamide
-
-
4-nitrobenzenesulfonamide
-
-
4-nitrophenyl sulfamate
-
-
4-phenoxyphenyl sulfamate
-
-
4-phenyl-1-(2-thioxobenzo[d]oxazol-3(2H)-yl)butan-1-one
-
-
4-phenylbenzene-1-sulfonamide
-
4-phenylphenyl sulfamate
-
-
4-S-isobutylamino-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
-
binds 800 times more strongly to carbonic anhydrase II than to carbonic anhydrase I
4-sulfamoyl-N-(4-sulfamoylphenyl)benzamide
-
-
4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamide
4-sulfamoylbenzoic acid
4-sulfosalicylic acid
-
uncompetitive inhibition of isozyme carbonic anhydrase I and competitive inhibition of isozyme carbonic anhydrase II
4-t-butylphenyl sulfamate
-
-
4-toluenesulfonamide
-
-
4-trichloromethylphenyl sulfamate
-
-
4-[(2-aminopyrimidin-4-yl)amino]benzene-1-sulfonamide
-
4-[(2-aminopyrimidin-4-yl)amino]benzenesulfonamide
4-[(2R)-2-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
-
4-[(2S)-2-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
-
4-[(3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)amino]benzenesulfonamide
-
4-[(3-fluorophenyl)ethynyl]benzenesulfonamide
-
-
4-[(3-hydroxyphenyl)ethynyl]benzenesulfonamide
-
-
4-[(3-methoxyphenyl)ethynyl]benzenesulfonamide
-
-
4-[(4-methylphenyl)ethynyl]benzenesulfonamide
-
-
4-[(acetyloxy)amino]-N-[4-(aminosulfonyl)phenyl]benzenesulfonamide
4-[(aminooxy)sulfinyl]-2-bromoaniline
-
-
4-[(aminooxy)sulfinyl]-2-chloroaniline
-
-
4-[(aminooxy)sulfinyl]-2-fluoroaniline
-
-
4-[(aminooxy)sulfinyl]-2-iodoaniline
-
-
4-[(aminooxy)sulfinyl]aniline
-
-
4-[(aminooxy)sulfinyl]benzoic acid
-
-
4-[(anilinocarbonyl)amino]-6-chlorobenzene-1,3-disulfonamide
4-[(methylsulfonyl)amino]benzenesulfonamide
4-[(phenylsulfonyl)amino]benzenesulfonamide
4-[(sulfoamino)sulfonyl]benzoic acid
4-[([(1Z)-[4-(dimethylamino)phenyl]methylidene]amino)methyl]benzenesulfonamide
-
-
4-[([[(diethyl-l5-azanylidyne)methyl]disulfanyl]amino)methyl]benzenesulfonamide
-
-
4-[2-(2-thienyl)acetamidoethyl]benzenesulfonamide
4-[2-(2-thienyl)acetamidomethyl]benzenesulfonamide
4-[2-(2-thienyl)acetamido]-3-bromobenzenesulfonamide
4-[2-(2-thienyl)acetamido]-3-chlorobenzenesulfonamide
4-[2-(2-thienyl)acetamido]-3-fluorobenzenesulfonamide
4-[2-(2-thienyl)acetamido]benzenesulfonamide
4-[2-(4-sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide
-
-
4-[2-[(2-oxo-2H-chromen-3-yl)carbonyl]hydrazino]benzenesulfonamide
-
-
4-[2-[(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl]hydrazino]benzenesulfonamide
-
-
4-[2-[(anilinocarbonothioyl)amino]ethyl]benzenesulfonamide
4-[2-[(anilinocarbonyl)amino]ethyl]benzenesulfonamide
4-[2-[([[4-(aminosulfonyl)phenyl]amino]carbonothioyl)amino]ethyl]benzenesulfonamide
4-[3-([(1E)-[4-(dimethylamino)phenyl]methylidene]amino)propyl]benzenesulfonamide
-
-
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4',6'-tetra-O-acetyl-alpha-D-mannopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4',6'-tetra-O-acetyl-beta-D-galactopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4',6'-tetra-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4'-tri-O-acetyl-alpha-D-arabinopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4'-tri-O-acetyl-beta-D-glucuronic acid methyl ester)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(2',3',5'-tri-O-benzoyl-beta-D-ribofuranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(2'-acetamido-2'-deoxy'-3',4',6'-tri-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(2'-acetamido-2'-deoxy-beta-D-glucopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(alpha-D-arabinopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-glucopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-glucuronic acid methyl ester)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-maltopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-ribofuranosyl)-1H-1,2,3-triazole
-
-
4-[4-(aminosulfonyl)phenyl]-1-(hepta-O-acetyl-beta-D-maltopyranosyl)-1H-1,2,3-triazole
-
-
4-[4-(methylsulfonyl)phenyl]-3-phenyldihydrofuran-2(3H)-one
-
-
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-bromoaniline
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-chloroaniline
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-fluoroaniline
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-iodoaniline
4-[cis-5-norbornene-endo-2,3-dicarboximidoethyl]-benzenesulfonamide
-
-
4-[cis-5-norbornene-endo-2,3-dicarboximidomethyl]-benzenesulfonamide
-
-
4-[cis-5-norbornene-endo-2,3-dicarboximido]-benzenesulfonamide
-
-
4-[cis-5-norbornene-endo-3-carboxy-2-carboxamidoethyl]-benzenesulfonamide
-
-
4-[cis-5-norbornene-endo-3-carboxy-2-carboxamidomethyl]-benzenesulfonamide
-
-
4-[cis-5-norbornene-endo-3-carboxy-2-carboxamido]-benzenesulfonamide
-
-
4-[N'-(1,1-dioxopyrido[4,3-e]-1,4,2-dithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
-
-
4-[N'-(6-chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
-
-
4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
-
-
4-[[(1Z)-(1-bromonaphthalen-2-yl)methylidene]amino]benzenesulfonamide
-
-
4-[[(2R,3R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
-
4-[[(2R,5S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
-
4-[[(3,4-dichlorophenyl)carbamoyl]amino]benzenesulfonamide
-
-
4-[[(3R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
-
4-[[(3R,4R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
-
4-[[(4R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
-
4-[[(5R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
-
4-[[(aminosulfonyl)amino]sulfonyl]benzoic acid
4-[[(anilinocarbonothioyl)amino]methyl]benzenesulfonamide
4-[[(diphenylcarbamoyl)amino]methyl]benzenesulfonamide
-
-
4-[[(phenylsulfonyl)amino]methyl]benzenesulfonamide
4-[[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
-
4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
-
5,5,5-tribromo-1,2,3,7,8,9,9a,11,16,17a-decahydro-5H-5lambda5-dipyrrolo[2,1-c:1',2'-f][1,4,6,9,5]benzotetraazastibacycloundecine-10,17-dione
5,6-diamino-1,3-dimethyluracil
inhibition of isozyme hCA I; inhibition of isozyme hCA II
5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
5-(2-phenylacetamido)-1,3,4-thiadiazole-2-sulfonamide
5-(3,7,12-trioxo-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(3-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
5-(3alpha,12alpha-dihydroxy-5-beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(3alpha,12alpha-dihydroxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(3alpha,7alpha,12alpha-triacetoxy-5-beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(3alpha,7alpha,12alpha-triacetoxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(3alpha,7alpha,12alpha-trihydroxy-5-beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(3alpha-acetoxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(3alpha-hydroxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(formylamino)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione
inhibition of isozyme hCA I
5-([(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-([(4-aminophenyl)sulfonyl]amino)-1,3,4-thiadiazole-2-sulfonamide
5-([(4-bromophenyl)sulfonyl]amino)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-([(4-nitrophenyl)sulfonyl]amino)-1,3,4-thiadiazole-2-sulfonamide
-
-
5-acetamido-1,3,4-thiadiazole-2-sulfonamide
5-amino-1,3,4-thiadiazole-2-sulfonamide
5-bromo-1-(4-methylbenzene-1-sulfonyl)pyrimidine-2,4(1H,3H)-dione
inhibition of isozyme hCA I; inhibition of isozyme hCA II
5-bromo-1-(methanesulfonyl)pyrimidine-2,4(1H,3H)-dione
inhibition of isozyme hCA I; inhibition of isozyme hCA II
5-chlorosalicylic acid
-
uncompetitive inhibition of isozymes carbonic anhydrase I and II
5-fluorouracil
-
5-imino-4-methyl-4,5-dihydro-1,3,4-thiadiazole-2-sulfonamide
5-pentylresorcinylsulfamate
-
-
5-sulfosalicylic acid
-
competitive inhibition of isozyme carbonic anhydrase I and noncompetitive inhibition of isozyme carbonic anhydrase II
5-[(2-phenylethyl)(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(aminooxy)sulfinyl]-1,3,4-thiadiazol-2-amine
-
-
5-[(aminooxy)sulfinyl]-3-methyl-1,3,4-thiadiazol-2(3H)-imine
-
-
5-[(benzenesulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
5-[(benzylsulfonyl)(2,4-dichlorobenzyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(benzylsulfonyl)(2-methylpropyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(benzylsulfonyl)(3,4,5-trimethoxybenzyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(benzylsulfonyl)(4-chlorobenzyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(benzylsulfonyl)(4-methoxybenzyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(benzylsulfonyl)(butyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(benzylsulfonyl)(dodecyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(benzylsulfonyl)(pentyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(benzylsulfonyl)(propan-2-yl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
5-[2-(2-thienyl)acetamido]-1,3,4-thiadiazole-2-sulfonamide
5-[benzyl(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[cis-5-norbornene-endo-2,3-dicarboximido]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[cis-5-norbornene-endo-3-carboxy-2-carboxamido]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[ethyl(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[methyl(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[[(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
-
5-[[(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino]-4,5-dihydro-1,3,4-thiadiazole-2-sulfonamide
5-[[(4-aminophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
5-[[(4-bromophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
5-[[(4-nitrophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
5-[[(pentafluorophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-[[(phenylcarbamoyl)carbamothioyl]amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{(2,4-dichlorobenzyl)[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{(4-bromobenzyl)[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{(4-chlorobenzyl)[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{(4-fluorobenzyl)[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{(4-methoxybenzyl)[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{(4-methylbenzyl)[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{(benzylsulfonyl)[2-(4-bromophenyl)ethyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{benzyl[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{butyl[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{dodecyl[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{ethyl[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{methyl[(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{[(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
5-{[(4-aminophenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
5-{[(4-methylphenyl)sulfonyl](2-methylpropyl)amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{[(4-methylphenyl)sulfonyl](2-phenylethyl)amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{[(4-methylphenyl)sulfonyl](3,4,5-trimethoxybenzyl)amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{[(4-methylphenyl)sulfonyl](pentyl)amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{[(4-methylphenyl)sulfonyl](propan-2-yl)amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{[(4-methylphenyl)sulfonyl](propyl)amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{[2-(4-bromophenyl)ethyl][(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
5-{[3-(2-methoxyphenyl)propyl][(4-methylphenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
-
-
6,6,6-trichloro-11-oxo-8,9,10,10a,11,12-hexahydro-6H-6lambda5-pyrimido[1,2-c]pyrrolo[2,1-g][1,3,5,2]triazastibepin-5-ium
6,7-dimethoxy-1-ethyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
6,7-dimethoxy-1-isopropyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
6,7-dimethoxy-1-propyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
-
6-((1S)-hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one
-
6-(1-hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one
-
-
6-(aminomethyl)-2H-chromen-2-one
-
6-(hydroxymethyl)-2-oxo-2H-chromene-3-carboxylic acid
-
6-(hydroxymethyl)-2H-chromen-2-one
-
6-acetyl-7-(benzyloxy)-2H-chromen-2-one
-
-
6-acetyl-7-adamantylethoxy-2H-chromen-2-one
-
-
6-acetyl-7-butoxy-2H-chromen-2-one
-
-
6-acetyl-7-ethoxy-2H-chromen-2-one
-
-
6-acetyl-7-hydroxy-2H-chromen-2-one
-
-
6-acetyl-7-methoxy-2H-chromen-2-one
-
-
6-acetyl-7-propoxy-2H-chromen-2-one
-
-
6-amino-1,3-dimethyluracil
inhibition of isozyme hCA I; inhibition of isozyme hCA II
6-amino-5-bromouracil
-
6-amino-5-chlorouracil
-
6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda6,2,4-benzothiadiazine-7-sulfonamide
6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~,2,4-benzothiadiazine-7-sulfonamide
-
-
6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
6-chloro-4-amino-benzene-1,3-disulfonamide
6-chloro-6,6-dimethyl-12-oxo-6,8,9,10,11,11a,12,13-octahydro-6lambda5-pyrido[2,1-g]pyrimido[1,2-c][1,3,5,2]triazastibepin-5-ium
6-deoxy-N-(4-sulfamoylphenyl)-alpha-L-mannopyranosylamine
-
6-deoxy-N-sulfamoyl-alpha-L-glucopyranosylamine
-
-
6-ethoxy-1,3-benzothiazole-2-sulfonamide
6-ethoxy-2-benzo-thiazolesulfonamide
-
-
6-ethoxyzolamide
-
-
6-hydroxy-1,3-benzothiazole-2-sulfonamide
6-methoxy-2-oxo-2H-chromene-3-carboxylic acid
-
6-methyl-2-oxo-2H-chromene-3-carboxylic acid
-
6-methyl-4-(methylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
6-methylpyrimidine-2,4(1H,3H)-dione
inhibition of isozyme hCA I
6-trifluoromethyl-4-aminobenzene-1,3-disulfonamide
667-coumate
7-(2-phenylethoxy)-2H-chromen-2-one
-
7-(benzyloxy)-2H-chromen-2-one
-
7-alpha-hydroxydehydroepiandrosterone sulfamate
-
-
7-butoxy-2H-chromen-2-one
-
7-ethoxy-2H-chromen-2-one
-
7-ethoxy-8-propanoyl-2H-chromen-2-one
-
-
7-hydroxy-1-methoxy-3-methyl-9-oxo-9,9a-dihydro-4aH-xanthene-8-carboxylic acid
-
-
7-hydroxy-3-(hydroxymethyl)-1-methoxy-9-oxo-9,9a-dihydro-4aH-xanthene-8-carboxylic acid
-
-
7-hydroxy-6-propanoyl-2H-chromen-2-one
-
-
7-hydroxy-8-propanoyl-2H-chromen-2-one
-
-
7-methoxy-2-oxo-2H-chromene-4-carboxylic acid
-
7-methoxy-2H-chromen-2-one
-
7-methoxy-8-propanoyl-2H-chromen-2-one
-
-
7-oxodehydroepiandrosterone sulfamate
-
-
7-propoxy-2H-chromen-2-one
-
7alpha-hydroxyepiandrosterone sulfamate
-
-
8-acetyl-7-(benzyloxy)-2H-chromen-2-one
-
-
8-acetyl-7-butoxy-2H-chromen-2-one
-
-
8-acetyl-7-ethoxy-2H-chromen-2-one
-
-
8-acetyl-7-hydroxy-2H-chromen-2-one
-
-
8-acetyl-7-methoxy-2H-chromen-2-one
-
-
8-acetyl-7-propoxy-2H-chromen-2-one
-
-
8-methoxy-2-oxo-2H-chromene-3-carboxylic acid
-
8-propanoyl-7-propoxy-2H-chromen-2-one
-
-
acetaldehyde
-
modification of carbonic anhydrase II with acetaldehyde leads to decreased enzyme activity, acetaldehyde (100 mM) in the presence of NaBH3(CN) causes 23.7% reduction in CA II activity, in the absence of NaBH3(CN) the activity is only slightly reduced
acetate
acetazolamide
acetic acid
-
-
Acetylsalicylic acid
-
noncompetitive inhibition of isozymes carbonic anhydrase I and II
allylamine hydrochloride
-
-
allylsulfonamide
-
-
allylsulfonamide hydrochloride
-
-
allylsulfonyl chloride
-
-
aminobenzolamide
-
-
ArSO2-NHPO3H2
-
-
Atrazine
-
-
azetazolamide
B4O72-
benzene-1,2-diol
benzene-1,3-diol
benzene-1,3-disulfonamide
benzene-1,4-diol
-
-
benzenesulfonamide
benzolamide
Benzyl (2-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-2-oxoethyl)carbamate
-
benzyl (2-((4-methylbenzo[d]thiazol-2-yl)amino)-2-oxoethyl)carbamate
-
benzyl (2-((6-(methylsulfonyl)benzo[d]thiazol-2-yl)amino)-2-oxoethyl)carbamate
-
benzyl (2E)-3-(3-hydroperoxy-4-hydroxyphenyl)prop-2-enoate
-
benzyl 2-thioxobenzo[d]oxazol-3(2H)-carboxylate
-
-
benzyl sulfamate
-
-
benzylsulfonylsulfamic acid
bicarbonate
bisulfate
weak, carbonic anhydrase XIII
bisulfite
brinzolamide
bromide
but-3-enyl sulfamate
-
-
but-3-ynyl sulfamate
-
-
Caffeine
-
-
callistephin
-
Carbaryl
carbofuran
-
-
Carbonate
catechin
-
a competitive inhibitor with 4-nitrophenylacetate as substrate
catechol
Cd2+
-
cadmium inhibits competitively
celecoxib
CF3SO2NH2
CF3SO3-
Chlorate
-
-
chlorazolamide
chloride
chlorothiazide
-
-
Chlorthalidone
chlorthalidone is a medium potency CA I, II, and IV inhibitor, a very effective inhibitor of CA VB, CA VII, CA IX, CA XII, and CA XIII and an ineffective inhibitor of isozymes CA III, VA, VI, and XIV
chlorzolamide
cholesteryl sulfamate
-
-
clioquinol
-
-
ClO4-
Co3+
-
competitive, strong inhibition of carbonic anhydrase esterase activity
CO32-
COS
-
3 mM, slightly inhibitory
coumarin
-
-
CS32-
Cu-GGHSLN
time-dependent inactivation of carbonic anhydrase I activity, within 3 h carbonic anhydrase I activity is eliminated at 0.005 mM Cu-GGHSLN
-
curcumin
cyanamide
-
-
Cyanate
cyanide
cyclohexyl sulfamate
-
-
cyclopentyl sulfamate
-
-
dehydroepiandrosterone sulfamate
dexamethasone
-
-
dextran-bound acetazolamide
-
dibenzyl N',N'''-(tribromo-lambda5-stibanediyl)biscarbamimidothioate
36.0% inhibition of CO2 hydration reaction after 30 min
dibenzyl N',N'''-(trichloro-lambda5-stibanediyl)biscarbamimidothioate
dichlorophenamide
diclofenamide
-
-
diethyl dicarbonate
Halalkalibacterium halodurans
strong inhibition at 5 mM
diethyldithiocarbamate
-
-
diflunisal
-
noncompetitive inhibition of isozymes carbonic anhydrase I and II
dimethylsilyl para-toluenesulfonamidoborane
-
-
dimethylsilyl-diphenylaminoborane
-
-
dimethylsilyl-N-methyl-N-phenylaminoborane
-
-
dimethylsilylaminoborane
-
-
dimethylsilylboronic acid
-
-
dimethylsilylfluoroborane
-
-
dimethylsilylsulfonamidoborane
-
-
dinitrosalicylic acid
-
-
dithiothreitol
dobutamin
dorzolamide
EMATE
-
-
EMD 486019
estradiol 17 beta-sulfamate
-
-
estradiol 3,17 beta-disulfamate
-
CA II inhibitor
estrone sulfamate
-
-
Et2NCS2-
ethanol
ethoxazolamide
-
systemic carbonic anhydrase inhibitor
ethoxyzolamide
ethoxzolamide
ethyl 2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylate 1,1-dioxide
-
-
ethyl 2-methyl-2H-thieno[3,2-e]-1,2-thiazine-3-carboxylate 1,1-dioxide
-
-
ethyl 3,4-dihydro-4-hydroxy-2H-thieno[3,2-e]-1,2-thiazine-3-carboxylate 1,1-dioxide
-
-
ethyl 3-(3-dimethylaminopropyl)-carbodiimide
Halalkalibacterium halodurans
80% inhibition at 5 mM, via irreversible modification of carboxyl groups or thepresence of catalytically active tyrosine in the enzyme molecule
ethyl 6-(hydroxymethyl)-2-oxo-2H-chromene-3-carboxylate
-
ethyl 7-methoxy-2-oxo-2H-chromene-3-carboxylate
-
ethyl sulfamate
-
-
ethylsulfonamide
-
-
fluorenylmethyl sulfamate
-
-
fluoride
FSO3-
Furosemide
guanidine hydrochloride
-
-
H2NSO2NH2
H2NSO3H
heptane-1,7-diyl disulfamate
-
histamine
-
-
homosulfanilamide
HSO3-
hydrochlorothiazide
hydrogen carbonate
hydrogen sulfide
hydrogen sulfite
hydrogencarbonate
good inhibitor of the Co(II)-substituted enzyme
hydrosulfide
-
Hydroxyurea
-
-
imidazole
indapamide
indapamide is a quite ineffective inhibitor of isozymes CA I, II, III, VA, VI, and XIV, a medium potency CA IV and CA VB inhibitor, and a very effective inhibitor of isozymes CA VII, IX, XII, and XIII
indisulam
Iodide
iodoacetate
-
-
iodoacetic acid
Halalkalibacterium halodurans
-
isocyanide
Isoorotic acid
inhibition of isozyme hCA I; inhibition of isozyme hCA II
isopropyl sulfamate
-
-
isopropylsulfonylsulfamic acid
ivermectin
-
-
K3[Fe(CN)6]
-
isoenzyme I
K4[Fe(CN)6]
-
isoenzyme I
L-adrenaline
-
-
mafenide
metamizole sodium
-
-
metazolamide
-
-
methazolamide
methyl (3-chloro-4-hydroxyphenyl)acetate
-
-
methyl 2-sulfanylbenzo[d]oxazole-5-carboxylate
-
27% inhibition
methyl 6-(hydroxymethyl)-2-oxo-2H-chromene-3-carboxylate
-
methyl N-[(2,3,4,6-Tetra-O-acetyl-beta-D-glucosyl)sulfonyl]-L-4'-sulfamoylprolinate
-
methyl N-[(2,3,4,6-tetra-O-acetyl-beta-D-glucosyl)sulfonyl]-L-sulfamoylserinate
-
methyl sulfamate
-
-
methyl-3-(3-phenylpropanoyl)-2,3-dihydro-2-thioxobenzo[d]oxazole-5-carboxylate
-
-
methylbenzolamide
-
-
methylsulfonamide
-
-
methylsulfonylsulfamic acid
Mn2+
-
73% residual activity at 1 mM
N'',N'''-bis[(E)-(2,3,4-trihydroxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(2,3-dihydroxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(2,4,6-trihydroxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-Bis[(E)-(2,4-dichlorophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(2,5-dihydroxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(2,6-dichlorophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(2-bromophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(2-chloro-5-nitrophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(2-chlorophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(2-fluorophenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(2-hydroxy-5-methoxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(2-hydroxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(2-methoxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(2-nitrophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(3,4-dimethoxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(3-ethoxy-2-hydroxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(3-hydroxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(3-methoxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(4-bromophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(4-chlorophenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(4-fluorophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(4-hydroxyphenyl)methylidene]carbonic dihydrazide
-
-
N'',N'''-bis[(E)-(4-methoxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-(4-nitrophenyl)methylidene]carbonic dihydrazide
N'',N'''-bis[(E)-(5-bromo-2-hydroxyphenyl)methylidene]carbonic dihydrazide
-
N'',N'''-bis[(E)-phenylmethylidene]carbonic dihydrazide
-
N,N'-biphosphoryl-4,5-dichloro-1,3-benzenesulfonamide
-
-
N,N'-bis(benzylsulfonyl)allylamine
-
-
N,N'-bis(styrenesulfonyl)allylamine
-
-
N,N-dimethylamidimidodisulfuric acid
N,N-dimethylimidodisulfuric diamide
N-(1,1-dimethylethyl)-2-(3-methoxyphenyl)-3-[(2-propylaminol)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
N-(1,1-dimethylethyl)-2-(3-methoxyphenyl)-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]-1,2-thiazine 1,1-dioxide
-
-
N-(1,1-dimethylethyl)-2-[4-(4-morpholinyl)-2-butenyl]-2H-thieno[3,2-e-]-1,2-thiazine-6-sulfonamide 1,1-dioxide
-
-
N-(1-(2-hydroxyphenylamino)-3-methyl-1-oxobutan-2-ylcarbamothioyl)benzamide
i.e. NK-154, binding structure, overview; i.e. NK-154, binding structure, overview; i.e. NK-154, binding structure, overview
N-(1-(2-hydroxyphenylamino)-4-methyl-1-oxopentan-2-ylcarbamothioyl) benzamide
i.e. NK-168, binding structure, overview; i.e. NK-168, binding structure, overview; i.e. NK-168, binding structure, overview
N-(2-fluoro-4-sulfamoylphenyl)-2-(thiophen-2-yl)acetamide
-
-
N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
N-(4-bromophenyl)sulfuric diamide
-
-
N-(4-sulfamoylbenzyl)benzenesulfonamide
-
-
N-(4-sulfamoylphenyl)-2-(thiophen-2-yl)acetamide
-
-
N-(4-sulfamoylphenyl)-beta-D-galactopyranosylamine
-
N-(4-sulfamoylphenyl)-beta-D-idopyranosylamine
-
N-(4-sulfamoylphenyl)acetamide
-
-
N-(4-sulfamoylphenyl)benzamide
-
-
N-(4-sulfamoylphenyl)butanamide
-
-
N-(4-sulfamoylphenyl)pentanamide
-
-
N-(4-sulfamoylphenyl)propanamide
-
-
N-(4-[(4-sulfamoylphenyl)sulfamoyl]phenyl)acetamide
-
-
N-(4-[(E)-[(aminosulfonyl)imino]methyl]phenyl)acetamide
N-(4-[[(aminosulfonyl)amino]sulfonyl]phenyl)acetamide
N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)acetamide
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)furan-2-carboxamide
N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
N-(allylsulfonyl)allylamine
-
-
N-(allysulfonyl)-3-triethylsilylpropanamine
-
-
N-(aminosulfonyl)-1,1,1-trichloromethanesulfonamide
N-(aminosulfonyl)-1,1,1-trifluoromethanesulfonamide
N-(aminosulfonyl)-1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonamide
N-(aminosulfonyl)-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonamide
N-(aminosulfonyl)-1-(7,7-dimethylbicyclo[2.2.1]hept-1-yl)methanesulfonamide
N-(aminosulfonyl)-1-phenylmethanesulfonamide
N-(aminosulfonyl)-2,3,4,5,6-pentafluorobenzenesulfonamide
N-(aminosulfonyl)-2,4,6-triisopropylbenzenesulfonamide
N-(aminosulfonyl)-2,4,6-tripropylbenzenesulfonamide
N-(aminosulfonyl)-2,5-dichlorobenzenesulfonamide
N-(aminosulfonyl)-2-nitrobenzenesulfonamide
N-(aminosulfonyl)-3,5-dichloro-2-hydroxybenzenesulfonamide
N-(aminosulfonyl)-3-(trifluoromethyl)benzenesulfonamide
N-(aminosulfonyl)-3-chloro-4-nitrobenzenesulfonamide
N-(aminosulfonyl)-3-nitrobenzenesulfonamide
N-(aminosulfonyl)-4-bromobenzenesulfonamide
N-(aminosulfonyl)-4-chlorobenzenesulfonamide
N-(aminosulfonyl)-4-fluorobenzenesulfonamide
N-(aminosulfonyl)-4-iodobenzenesulfonamide
N-(aminosulfonyl)-4-methoxybenzenesulfonamide
N-(aminosulfonyl)-4-methylbenzenesulfonamide
N-(aminosulfonyl)-4-nitrobenzenesulfonamide
N-(aminosulfonyl)-5-(dimethylamino)naphthalene-1-sulfonamide
N-(aminosulfonyl)benzenesulfonamide
N-(aminosulfonyl)methanesulfonamide
N-(aminosulfonyl)naphthalene-1-sulfonamide
N-(aminosulfonyl)naphthalene-2-sulfonamide
N-(aminosulfonyl)propane-2-sulfonamide
N-(aminosulfonyl)quinoline-8-sulfonamide
N-(aminosulfonyl)thiophene-2-sulfonamide
N-(benzylsulfonyl)-3-tributylgermylpropanamine
-
-
N-(benzylsulfonyl)-3-triethylsilylpropanamine
-
-
N-(benzylsulfonyl)allylamine
-
-
N-(cyclopropylmethyl)-3-(1,3-dioxolan-2-yl)thiophene-2-sulfonamide
-
-
N-(dimesilylboro)allylsulfonamide
-
-
N-(styrenesulfonyl)-3-triethylsilylpropanamine
-
-
N-(trans-styrenesulfonyl)allylamine
-
-
N-2'-sulfamoylethyl-S-(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-3'-R-sulfamoylpyrrolidinyl-S-(1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-3'-R-sulfamoylpyrrolidinyl-S-(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-3'-sulfamoylpropyl-S-(1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-3'-sulfamoylpropyl-S-(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-4'-sulfamoylpiperidinyl-S-(1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-4'-sulfamoylpiperidinyl-S-(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-4-methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanine hydroxamate
N-4-methoxyphenylsulfonyl-N-benzyl-L-valine hydroxamate
N-5'-sulfamoylpentyl-S-(1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-5'-sulfamoylpentyl-S-(2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranosyl)sulfonamide
-
N-allyl-1-phenylmethanesulfonamide
-
-
N-allylsulfonyl-3-[9-borabicyclo[1.3.3.]nonane]propanamine
-
-
N-benzyl-2-(3-chloro-4-hydroxyphenyl)acetamide
-
-
N-bromosuccinimide
Halalkalibacterium halodurans
strong inhibition at 5 mM
n-butyl sulfamate
-
-
N-butyl-2-(3-chloro-4-hydroxyphenyl)acetamide
-
-
N-cyclohexyl-N-[(3-formyl-thien-2-yl)sulfonyl]-glycine methyl ester
-
-
N-cyclopropylmethyl-3-(1,3-dioxolan-2-yl)-2-thiophenesulfonamide
-
-
n-decyl sulfamate
-
CA II inhibitor
n-dodecyl sulfamate
-
-
N-ethylmaleimide
Halalkalibacterium halodurans
strong inhibition at 5 mM
n-hexadecyl sulfamate
-
-
n-hexanesulfonamide
n-hexylsulfonamide
-
-
N-hydroxysulfamide
isoenzyme hCA I; isoenzyme hCA IX; isoenzyme hCA XII; the inhibitor coordinates to the active site zinc ion by the ionized primary amino group, participating in an extended network of hydrogen bonds with amino acid residues Thr199, Thr200 and two water molecules, isoenzyme hCA II
N-hydroxysulfonamide
N-n-perfluorobutylsulfonyl-alanine hydroxamate
n-octadecyl sulfamate
-
-
n-octanesulfonamide
n-octyl sulfamate
N-pentafluorophenylsulfonyl-glycine
N-pentafluorophenylsulfonyl-glycine hydroxamate
N-pentafluorophenylsulfonyl-N-4-nitrobenzyl-glycine hydroxamate
n-pentyl sulfamate
-
-
N-phenylsulfuric diamide
-
-
N-phosphoryl-4-carboxy-benzenesulfonamide
-
-
N-phosphoryl-6-nitro-benzothiazole-2-sulfonamide
-
-
N-phosphoryl-benzothiazole -2-sulfonamide
-
-
n-propyl sulfamate
-
-
N-salicylidene-sulfanilic acid amide
N-salicylidene-sulfanilic acid amide cobalt acetate complex
N-salicylidene-sulfanilic acid amide cobalt chloride complex
N-salicylidene-sulfanilic acid amide cobalt nitrate complex
N-salicylidene-sulfanilic acid amide cobalt sulfate complex
N-salicylidene-sulfanilic acid amide copper chloride complex
N-salicylidene-sulfanilic acid amide copper nitrate complex
N-salicylidene-sulfanilic acid amide nickel acetate complex
N-salicylidene-sulfanilic acid amide nickel chloride complex
N-salicylidene-sulfanilic acid amide nickel nitrate complex
N-salicylidene-sulfanilic acid amide nickel sulfate complex
N-sulfamoyl-beta-D-galactopyranosylamine
-
-
N-sulfamoyl-beta-D-glucopyranosylamine
-
-
N-sulfamoyl-beta-D-mannopyranosylamine
-
-
N-tert-butyl-2-(3-chloro-4-hydroxyphenyl)acetamide
-
-
n-tetradecyl sulfamate
-
most potent CA I inhibitor
N-trimethylsilylallylsulfonamide
-
-
n-undecyl sulfamate
-
-
N-[(1E)-(1-methyl-1H-pyrrol-2-yl)methylene]sulfamide
N-[(1E)-(3,4,5-trimethoxyphenyl)methylene]sulfamide
N-[(1E)-(3-nitrophenyl)methylene]sulfamide
N-[(1E)-(4-methoxyphenyl)methylene]sulfamide
N-[(1E)-(4-methylphenyl)methylene]sulfamide
N-[(1E)-(4-nitrophenyl)methylene]sulfamide
N-[(1E)-(5-methylthien-2-yl)methylene]sulfamide
N-[(1E)-phenylmethylene]sulfamide
N-[(1E)-thien-2-ylmethylene]sulfamide
N-[(1E)-[4-(dimethylamino)phenyl]methylene]sulfamide
N-[(2E)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
N-[(2E)-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]furan-2-carboxamide
-
-
N-[(3-formyl-2-thienyl)sulfonyl]-glycine ethyl ester
-
-
N-[(3-formyl-thien-2-yl)sulfonyl]-N-(2-methoxyethyl)-glycine ethyl ester
-
-
N-[(3aR,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]sulfamic amide
-
-
N-[(4-[[(4-sulfamoylphenyl)carbamothioyl]amino]phenyl)sulfonyl]acetamide
-
-
N-[2,4-disulfamoyl-5-(trifluoromethyl)phenyl]-2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetamide
-
-
N-[2,4-disulfamoyl-5-(trifluoromethyl)phenyl]-2-oxo-2H-chromene-3-carboxamide
-
-
N-[4-(aminosulfonyl)phenyl]-2,2,2-trifluoroacetamide
N-[4-(aminosulfonyl)phenyl]-2,2-dimethylpropanamide
N-[4-(aminosulfonyl)phenyl]-2-methylpropanamide
N-[4-(aminosulfonyl)phenyl]acetamide
N-[4-(aminosulfonyl)phenyl]benzamide
N-[4-(aminosulfonyl)phenyl]butanamide
N-[4-(aminosulfonyl)phenyl]pentanamide
N-[4-(aminosulfonyl)phenyl]propanamide
N-[4-[(aminooxy)sulfinyl]phenyl]-4-[(diphenylcarbamoyl)amino]benzenesulfonamide
-
-
N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
N-[5-[(aminooxy)sulfinyl]-1,3,4-thiadiazol-2-yl]-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonamide
-
-
N-[[2-(1,3-dioxalan-2-yl)-3-thienyl]sulfonyl]-N-methylglycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)-2-thienyl]sulfonyl]-glycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-(1-methylethyl)-glycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-(2-propenyl)-glycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-(3-methoxyethyl)-glycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-ethylglycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-methylcyclopropyl-glycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-methylglycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-propylglycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-[(3,4-dimethoxyphenyl)methyl]-glycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-[(3-methoxyphenyl)methyl]-glycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-[(4-methoxyphenyl)methyl]-glycine ethyl ester
-
-
N-[[3-(1,3-dioxolan-2-yl)thien-2-yl]sulfonyl]-N-[4-(morpholin-4-yl)phenyl]-glycine methyl ester
-
-
N-[[5-(aminosulfonyl)-2-formyl-thiophen-3-yl]sulfonyl]-N-methyl-glycine ethyl ester
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-alanine
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-asparagine
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-glutamine
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-isoleucine
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-leucine
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-methionine
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-phenylalanine
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-proline
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-tryptophan
-
-
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-valine
-
-
Na2S
-
-
naphthalene-2-sulfonamide
-
-
NH(SO3)22-
nitrate
nitrite
N~1~-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
-
o-Iodosobenzoate
octane-1-sulfonamide
-
-
Orotic acid
inhibition of isozyme hCA I; inhibition of isozyme hCA II
orthanilamide
carbonic anhydrase XIII
p-(aminomethyl)-benzene-sulfonamide
a CAII inhibitor
p-(aminomethyl)-benzenesulfonamide
p-AMBS
p-aminomethylbenzenesulfonamide
p-biphenylmethyl sulfamate
-
-
p-hydroxymercuribenzoate
Macropus eugenii desmarest
-
-
p-methylbenzyl sulfamate
-
-
p-toluenesulfonamide
P2O74-
paracetamol
-
-
pentachlorophenyl sulfamate
-
-
pentafluorophenyl sulfamate
-
-
perchlorate
perfluorobutanesulfonamide
Ph-AsO3H2
Ph-B(OH)2
PH2BOH
-
-
phenol
phenyl arsonic acid
phenyl boronic acid
phenyl methyl sulfonyl fluoride
-
-
phenyl sulfamate
phenyl-boronic acid
-
-
phenylacetonitrile
-
-
phenylarsonic acid
phenylboronic acid
phenylsulfamate
-
best CA I inhibitor
phenylsulfonylsulfamic acid
phosphate
binding structure analysis, overview. Phosphate binds to the catalytic zinc cofactor, each unit cell is comprised of four dimers of CrCAH3
PMSF
Halalkalibacterium halodurans
80% inhibition at 5 mM
prontosil
-
prop-2-ene-1-sulfonamide
-
-
propoxur
-
-
pyridoxal 5'-phosphate
-
-
quinolin-8-ylsulfonylsulfamic acid
ReO4-
resorcinol
resveratrol
rofecoxib
-
-
Rose bengal
-
-
RuO4-
RWJ-37497
-
S2O82-
saccharin
salicylic acid
SeCN-
SeO42-
silychristin
-
silymarin
-
a competitive inhibitor with 4-nitrophenylacetate as substrate
simazine
-
-
SnO32-
SO32-
-
-
SO42-
sodium (butylsulfonyl)azanide
-
-
sodium (hexylsulfonyl)azanide
-
-
sodium (octylsulfonyl)azanide
-
-
spermine
-
-
Sulfadiazine
-
-
Sulfaguanidine
-
-
sulfamate
sulfamethazine
-
-
sulfamezathine
-
-
sulfamic acid
sulfamide
sulfanilamide
sulfasalazine
-
noncompetitive inhibition of isozymes carbonic anhydrase I and II
sulfate
sulfonamide
Sulfonamides
-
affinity of carbonic anhydrase IV for sulfonamides is decreased up to 65fold compared to carbonic anhydrase II
sulphanilamide
sulpiride
sulthiame
tavilin 50
-
-
tebuconazole
-
-
TeO42-
tert-butyl (2-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-2-oxoethyl)carbamate
-
tert-butyl (2-((4-methylbenzo[d]thiazol-2-yl)amino)-2-oxoethyl)-carbamate
-
tert-butyl (2-((6-(methylsulfonyl)benzo[d]thiazol-2-yl)amino)-2-oxoethyl)carbamate
-
tert-butyl 3-[[(aminosulfonyl)amino]sulfonyl]phenylcarbamate
tert-butyl 4-[[(aminosulfonyl)amino]sulfonyl]phenylcarbamate
tert-butyl 5-[[(aminosulfonyl)amino]sulfonyl]-2-hydroperoxyphenylcarbamate
tetrafluoroborate
-
tetramisol
-
-
thien-2-ylsulfonylsulfamic acid
thiocyanate
Thiocyanide
topiramate
trifluoromethanesulfonamide
U-shaped pH-dependence of the Gibbs energy of binding, the affinity is greatest in the near neutral pH region and diminished towards both the acidic and alkaline regions
tris(hydroxymethyl)phosphine
-
-
Triton X-100
Halalkalibacterium halodurans
-
Tween 80
Halalkalibacterium halodurans
-
umbelliferone
-
-
Urea
-
-
V2O74-
valdecoxib
Woodward's reagent K
Halalkalibacterium halodurans
WRK
zonisamide
[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-2H,3aH,7H-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate
-
[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate
[(7,7-dimethylbicyclo[2.2.1]hept-1-yl)methyl]sulfonylsulfamic acid
[3-(trifluoromethyl)phenyl]sulfonylsulfamic acid
[3-[(tert-butoxycarbonyl)amino]-4-hydroperoxyphenyl]sulfonylsulfamic acid
[3-[(tert-butoxycarbonyl)amino]phenyl]sulfonylsulfamic acid
[4-(acetylamino)phenyl]sulfonylsulfamic acid
[4-[(aminooxy)sulfinyl]phenyl]methanol
-
-
[4-[(tert-butoxycarbonyl)amino]phenyl]sulfonylsulfamic acid
[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]hydrazine
[5-(dimethylamino)-1-naphthyl]sulfonylsulfamic acid
[Co(1-benzyl-2-methylimidazole)2Cl2]
-
[Hg(1-benzyl-2-methylimidazole)2Cl2]
-
[S2O8]2-
-
-
[Zn(1-benzyl-2-methylimidazole)2Cl2]
-
[[(2-methylphenyl)sulfonyl]amino]carbonylsulfamic acid
[[(2-methylphenyl)sulfonyl]amino]carbonylsulfamic amide
[[(4-chlorophenyl)sulfonyl]amino]carbonylsulfamic acid
[[(4-chlorophenyl)sulfonyl]amino]carbonylsulfamic amide
[[(4-fluorophenyl)sulfonyl]amino]carbonylsulfamic acid
[[(4-fluorophenyl)sulfonyl]amino]carbonylsulfamic amide
[[(4-methylphenyl)sulfonyl]amino]carbonylsulfamic acid
[[(4-methylphenyl)sulfonyl]amino]carbonylsulfamic amide
additional information
-