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4.2.1.1: carbonic anhydrase

This is an abbreviated version!
For detailed information about carbonic anhydrase, go to the full flat file.

Word Map on EC 4.2.1.1

Reaction

H2CO3
=
CO2
 +
H2O

Synonyms

(CA) XIV, AaCA1, alkalistable alpha-carbonic anhydrase, alpha carbonic anhydrase, alpha class carbonic anhydrase, alpha-CA, alpha-carbonic anhydrase, alpha-carbonic anhydrase isozyme II, alpha-class carbonic anhydrase, alpha-type CA, alpha-type carbonic anhydrase, alphaCA, alphaCA1, Am CA, AmCA, anhydrase, ASCA, AtCA1, AtCA2, AtCAL1, AtCAL2, B13-CA, BCA II, bCA IV, BCAII, BCAIIGln253Cys, beta carbonic anhydrase, beta-CA, beta-carbonic anhydrase, beta-class carbonic anhydrase, betaCA, betaCA1, BhCA, bovine carbonic anhydrase II, bsCA I, bsCA II, CA, CA 1, CA 3, CA I, CA II, CA III, CA IV, CA IX, CA VA, CA VB, CA VI, CA VII, CA VIII, CA XII, CA XIII, CA XIV, Ca XV, CA-I, CA-II, CA-III, CA-IX, CA-VA, CA-VB, CA-VI, CA-VII, CA-XII, CA-XIV, CA1, CA14x, CA2, CA2 homolog, CA2-like, CA3, CA4, CA5A, CA6, CA9, CAA, CAA1, CAA2, Cab, cab-type beta-class carbonic anhydrase, cadmium carbonic anhydrase, CAH3, CAH7, CAH8, CAI, CAII, CAIII, CAIV, CAIX, Cam, CamH, CaN, Can2, canA, canB, CaNce103, carbonate anhydrase, Carbonate dehydratase, carbonate dehydratase I, carbonate dehydratase III, Carbonate dehydratase IX, Carbonate dehydratase VA, Carbonate dehydratase VB, Carbonate dehydratase VI, Carbonate dehydratase VII, Carbonate dehydratase XII, Carbonate dehydratase XIV, carbonate hydro-lyase, carbonate hydrolase, carbonate hydrolyase, carbonic acid anhydrase, carbonic anhydrase, carbonic anhydrase 1, carbonic anhydrase 14, carbonic anhydrase 2, carbonic anhydrase 3, carbonic anhydrase 5A, carbonic anhydrase 6, carbonic anhydrase 9, carbonic anhydrase cambialistic enzyme, carbonic anhydrase I, carbonic anhydrase I (CA I) Michigan 1, carbonic anhydrase II, carbonic anhydrase III, carbonic anhydrase isozyme I, carbonic anhydrase isozyme II, carbonic anhydrase isozyme III, carbonic anhydrase isozyme IV, carbonic anhydrase isozyme IX, carbonic anhydrase IV, carbonic anhydrase IX, carbonic anhydrase type III, carbonic anhydrase V, carbonic anhydrase VA, carbonic anhydrase VI, carbonic anhydrase VII, carbonic anhydrase XII, carbonic anhydrase XIII, carbonic anhydrase XIV, carbonic anhydrase XV, carbonic anhydrase-I, carbonic anhydrase-II, carbonic anhydrase-related protein, carbonic anhydrase-related protein VIII, carbonic dehydratase, carboxyanhydrase, CARP, CAS1, CAS2, CasCAc, CasCAg, CAV, CAVA, CAXII, CcaA, CcmM, CDCA1, chloroplast carbonic anhydrase, clCA, CmCA, CO2 hydrase, CO2 hydratase, CPB, CpsCA, CpsCAgamma, CrCAH3, CsoSCA, cynT, CynT2, cytoplasmic carbonic anhydrase, Dca, dCA I, dCA II, dCAII, DDCA, dehydratase, carbonate, delta carbonic anhydrase, delta-carbonic anhydrase, delta-class CA, diatom carbonic anhydrase, Dsp-aCAopt sp., dual domain-carbonic anhydrase, dual-domain carbonic anhydrase, DVU_1777, E84A MTCA, eCA, ECCA, erythrocyte carbonic anhydrase, eta-CA, eta-carbonic anhydrase, external carbonic anhydrase, extracellular carbonic anhydrase, FbiCA 1, fCA, gamma carbonic anhydrase 1, gamma carbonic anhydrase 2, gamma carbonic anhydrase-like 1, gamma carbonic anhydrase-like 2, gamma-CA, gamma-CA1, gamma-CA2, gamma-CAL1, gamma-CAL2, gamma-carbonic anhydrase, gamma-class carbonic anhydrase, gammaCA, H216N ATCA, H64A HCA II, HC II, HCA, hCA I, HCA II, hCA III, hCA IV, hCA IX, hCA VA, hCA VB, hCA VI, hCA VII, hCA XII, hCA XIV, hCA XIV catalytic domain, HCA-I, HCA-II, hCAII, HcCA3, HICA, HP1186, hpalphaCA, hpbetaCA, human carbonic anhydrase, human carbonic anhydrase I, human carbonic anhydrase II, human carbonic anhydrase III, human carbonic anhydrase isoenzyme I, human carbonic anhydrase isoenzyme II, human carbonic anhydrase IX, human carbonic anhydrase XII, human carbonic anhydrase XIV, Ice-CA, icfA, isozyme CA II, isozyme CA IV, LdcCA, luminal carbonic anhydrase, lwCA, mCA V, mCA XIII, Membrane antigen MN, mesohalophilic carbonic anhydrase, MG-CA, MgaCA, More, mtcA1, mtcA2, MtCam, MTCY373.03, Nce103, NcoCA, NGCA, NstCcmM209, OEC33 protein, P54/58N, pentraxin-CA VI, pentraxin-carbonic anhydrase, PERMA_1443, PF3D7_1140000, PfCAdom, PgiCA, PgiCAb, PGJ_00014320, PhaCAgamma, PhCamH, photosystem II-associated carbonic anhydrase, Pl-can, plant-type (beta-class) carbonic anhydrase, PMCA, pMW1, poly-[Hb-SOD-CAT-CA], polyhemoglobin-superoxide dismutase-catalase-carbonic anhydrase, PtCA1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250, RT erythrocyte CA, Rv1248, Rv1284, Rv3273, Rv3588c, SABP3, Salivary carbonic anhydrase, SazCA, scCA, Secreted carbonic anhydrase, secretory carbonic anhydrase, secretory carbonic anhydrase VI, SspCA, STPCA, STPCA-2, SULAZ_0541, TacA, TCAb, TCAc, TcCA, Tcru, Tcr_1545, Theam_1576, tobacco salicylic acid-binding protein 3, Tumor antigen HOM-RCC-3.1.3, TWCA1, TweCA, VchCA

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.1 carbonic anhydrase

KI Value

KI Value on EC 4.2.1.1 - carbonic anhydrase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0004 - 0.003
(2,4,6-triisopropylphenyl)sulfonylsulfamic acid
0.0008 - 0.005
(2,4,6-tripropylphenyl)sulfonylsulfamic acid
0.00001 - 0.0009
(2,5-dichlorophenyl)sulfonylsulfamic acid
0.0009 - 0.004
(2-nitrophenyl)sulfonylsulfamic acid
0.00334 - 0.35
(2E)-2-[(4-hydroxy-3-methylphenyl)methylidene]-N-(5-sulfanylidene-4,5-dihydro-1,3,4-thiadiazol-2-yl)hydrazine-1-carboxamide
0.00383 - 0.00803
(2E)-2-[(4-hydroxyphenyl)methylidene]-N-(5-sulfanylidene-4,5-dihydro-1,3,4-thiadiazol-2-yl)hydrazine-1-carboxamide
0.00536 - 0.0067
(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid
0.0024 - 0.00713
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
0.000098 - 0.284
(2E)-4-methoxy-4-oxobut-2-enoic acid
0.00009 - 0.395
(2E)-but-2-enedioic acid
0.000095 - 0.239
(2R)-3-(3-chloro-4-hydroxyphenyl)-2-[[(2E)-4-methoxy-4-oxobut-2-enoyl]amino]propanoic acid
0.000102 - 0.231
(2S)-3-(3-chloro-4-hydroxyphenyl)-2-[[(2E)-4-methoxy-4-oxobut-2-enoyl]amino]propanoic acid
0.000079 - 0.000144
(2Z)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
0.0000134 - 0.0000431
(2Z)-2-(3-bromobenzylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
0.0000345 - 0.0000401
(2Z)-2-(3-methoxybenzylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
0.0000184 - 0.0000953
(2Z)-2-(4-chlorobenzylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
0.0000331
(2Z)-2-(4-fluorobenzylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
-
pH 7.5, 20°C
0.0000195 - 0.0000524
(2Z)-2-(4-methylpentan-2-ylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
0.0000725 - 0.000152
(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
0.0000211 - 0.0000279
(2Z)-2-benzylidene-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
0.0003 - 0.0021
(3,5-dichloro-2-hydroxyphenyl)sulfonylsulfamic acid
0.0001 - 0.265
(3-chloro-4-hydroxyphenyl)acetic acid
0.00009 - 0.002
(3-chloro-4-nitrophenyl)sulfonylsulfamic acid
0.000085 - 0.244
(3-chlorophenyl)acetic acid
0.0002 - 0.004
(3-nitrophenyl)sulfonylsulfamic acid
0.0000038 - 0.00025
(3aR,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl sulfamate
0.0018 - 0.01
(4-acetylphenyl)sulfonylsulfamic acid
0.01 - 0.03
(4-bromophenyl)sulfonylsulfamic acid
0.01 - 0.03
(4-chlorophenyl)sulfonylsulfamic acid
0.01 - 0.04
(4-fluorophenyl)sulfonylsulfamic acid
0.000099 - 0.309
(4-hydroxyphenyl)acetic acid
0.009 - 0.03
(4-iodophenyl)sulfonylsulfamic acid
0.003 - 0.02
(4-methoxyphenyl)sulfonylsulfamic acid
0.01 - 0.03
(4-methylphenyl)sulfonylsulfamic acid
0.0001 - 0.003
(4-nitrophenyl)sulfonylsulfamic acid
0.00026 - 0.007835
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~-thieno[3,2-e][1,2]thiazine-6-sulfonamide
0.0000025 - 0.084
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
0.0000063 - 0.079
(4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
0.000963 - 0.00794
(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda~6~-thieno[2,3-b]thiopyran-2-sulfonamide
0.000076 - 0.355
(5Z)-2-amino-5-(3,4-dihydroxybenzylidene)-3,5-dihydro-4H-imidazol-4-one
0.00007 - 0.0105
(5Z)-2-amino-5-(4-hydroxy-3-methoxybenzylidene)-3,5-dihydro-4H-imidazol-4-one
0.0018 - 0.03
(heptadecafluorooctyl)sulfonylsulfamic acid
0.003 - 0.04
(nonafluorobutyl)sulfonylsulfamic acid
0.000003 - 0.0008
(pentafluorophenyl)sulfonylsulfamic acid
0.0000036 - 0.001207
(R)- 4-(2-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000334 - 0.000205
(R)- 4-(4-benzoyl-2-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000029 - 0.000198
(R)-1-[4-(benzenesulfonyl)-2-benzylpiperazin-1-yl]ethan-1-one
0.0000051 - 0.002626
(R)-17(R)-4-[2-benzyl-4-(4-sulfamoylbenzoyl)piperazine-1-carbonyl]benzene-1-sulfonamide
0.0000669 - 0.002639
(R)-4-(2,4-dibenzylpiperazine-1-carbonyl)benzenesulfonamide
0.000002 - 0.000232
(R)-4-(2-benzyl-4-methanesulfonylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000377
(R)-4-(2-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
inhibition of isozyme, pH 9.0, 40°C
0.0000023 - 0.0004185
(R)-4-(3,4-dibenzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.000019 - 0.000181
(R)-4-(3-benzyl-4-methanesulfonylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000017 - 0.001811
(R)-4-(3-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000046 - 0.001718
(R)-4-(3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000033 - 0.0002273
(R)-4-(4-acetyl-3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000443
(R)-4-(4-benzoyl-2-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
inhibition of isozyme, pH 9.0, 40°C
0.000004 - 0.001659
(R)-4-(4-benzoyl-3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000023 - 0.000166
(R)-4-[2-benzyl-4-(2-phenylacetyl)piperazine-1-carbonyl]benzene-1-sulfonamide
0.0000026 - 0.00152
(R)-4-[3-benzyl-4-(2-phenylacetyl)piperazine-1-carbonyl]benzene-1-sulfonamide
0.0000036 - 0.001207
(R)-4-[4-(benzenesulfonyl)-2-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
0.0000062 - 0.00036
(R)-4-[4-(benzenesulfonyl)-3-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
0.0003425 - 0.001432
(S)- 4-(2-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000078 - 0.000227
(S)- 4-(4-benzoyl-2-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.000006 - 0.00017
(S)-1-[4-(benzenesulfonyl)-2-benzylpiperazin-1-yl]ethan-1-one
4.1
(S)-2-(2-ammoniopropanamido)-4-methylbenzo[d]thiazol-3-ium di-2,2,2-trifluoroacetate
pH 7.5, 22°C
0.0000279 - 0.0000889
(S)-4-(2,4-dibenzylpiperazine-1-carbonyl)benzenesulfonamide
0.0000316 - 0.000186
(S)-4-(2-benzyl-4-methanesulfonylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.000707
(S)-4-(2-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
inhibition of isozyme, pH 9.0, 40°C
0.0000083 - 0.00025
(S)-4-(3,4-dibenzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.000006 - 0.0000797
(S)-4-(3-benzyl-4-methanesulfonylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.000146 - 0.001716
(S)-4-(3-benzyl-4-methylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000293 - 0.000225
(S)-4-(3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000076 - 0.0000837
(S)-4-(4-acetyl-3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000828
(S)-4-(4-benzoyl-2-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
inhibition of isozyme, pH 9.0, 40°C
0.000015 - 0.000245
(S)-4-(4-benzoyl-3-benzylpiperazine-1-carbonyl)benzene-1-sulfonamide
0.0000054 - 0.000191
(S)-4-[2-benzyl-4-(2-phenylacetyl)piperazine-1-carbonyl]benzene-1-sulfonamide
0.000002 - 0.000139
(S)-4-[2-benzyl-4-(4-sulfamoylbenzoyl)piperazine-1-carbonyl]benzene-1-sulfonamide
0.0000927 - 0.0005426
(S)-4-[3-benzyl-4-(2-phenylacetyl)piperazine-1-carbonyl]benzene-1-sulfonamide
0.0000078 - 0.0003303
(S)-4-[4-(benzenesulfonyl)-2-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
0.0000622 - 0.001589
(S)-4-[4-(benzenesulfonyl)-3-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
0.005 - 0.0711
(S)-benzyl (1-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-1-oxopropan-2-yl)carbamate
0.0726
(S)-benzyl (1-((4-methylbenzo[d]thiazol-2-yl)amino)-1-oxopropan-2-yl)carbamate
pH 7.5, 22°C
0.0847
(S)-tert-butyl (1-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
pH 7.5, 22°C
4.1
(S)-tert-butyl (1-((4-methylbenzo[d]thiazol-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
pH 7.5, 22°C
0.086
(S)-tert-butyl (1-((4-methylbenzo[d]thiazol-2-yl)amino)-1-oxopropan-2-yl)carbamate
pH 7.5, 22°C
0.0454
(S)-tert-butyl (1-((6-(methylsulfonyl)benzo[d]thiazol-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
pH 7.5, 22°C
0.01 - 0.05
(trichloromethyl)sulfonylsulfamic acid
0.01 - 0.05
(trifluoromethyl)sulfonylsulfamic acid
0.00143 - 0.0078
1,2,4-trimethoxybenzene
0.000751 - 0.1
1,2-benzothiazol-3(2H)-one 1,1-dioxide
0.0005 - 0.0104
1,2-dimethoxybenzene
0.000029 - 0.000315
1,2:3,4-di-O-isopropylidene-alpha-D-galactopyranose 6-sulfamate
0.000015 - 0.000278
1,2:5,6-di-O-isopropylidene-alpha-D-glucofuranose 3-sulfamate
0.1664 - 0.3162
1,3-dimethylpyrimidine-2,4(1H,3H)-dione
0.00335 - 0.00821
1,4-dimethoxybenzene
0.00015 - 0.105
1,5-bis[amino(dihydroxy)-lambda4-sulfanyl]-2,3-dichlorobenzene
0.000035 - 0.1
1-(1,2-benzoxazol-3-yl)methanesulfonamide
0.0000055 - 0.00065
1-cyclohexyl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.0004 - 0.35
1-cyclopentyl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.0000047 - 0.00378
1-cyclopropyl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.0000064 - 0.00395
1-n-butyl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.0015 - 0.009
1-naphthylsulfonylsulfamic acid
0.000048 - 0.0089
1-[(2-oxo-2H-chromen-6-yl)methyl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane
0.00046 - 0.0044
1-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-4-(4-sulfamoylphenyl)-1H-1,2,3-triazole
0.00027 - 0.0257
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]ethanamine
0.00035 - 0.0285
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]methanamine
0.000142 - 1
1H,1H,2H,2H-perfluorodecyl sulfamate
0.000335 - 0.4
1H,1H,2H,2H-perfluorooctyl sulfamate
0.000458 - 0.0078
1H,1H-perfluoroethyl sulfamate
0.000279 - 0.00354
1H-perfluoroisopropyl sulfamate
0.000325
2,2,2-trifluoro-N-(4-sulfamoylphenyl)acetamide
-
pH 7.5, 20°C
0.003055
2,3,4,5,6-pentafluoro-N-(2-sulfamoylphenyl)benzenesulfonamide
-
-
0.003441
2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)benzamide
-
-
0.006867
2,3,4,5,6-pentafluoro-N-[(2E)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]benzamide
-
-
0.0000065 - 0.008637
2,3,4,6-tetra-O-acetyl-N-sulfamoyl-beta-D-galactopyranosylamine
0.0000054 - 0.003714
2,3,4,6-tetra-O-acetyl-N-sulfamoyl-beta-D-glucopyranosylamine
0.000005 - 0.009703
2,3,4,6-tetra-O-acetyl-N-sulfamoyl-beta-D-mannopyranosylamine
0.0000053 - 0.00953
2,3,4-tri-O-acetyl-6-deoxy-N-sulfamoyl-alpha-L-glucopyranosylamine
0.000037 - 0.000454
2,4,6-trichlorophenyl sulfamate
0.00083 - 0.05
2,4-bis[amino(dihydroxy)-lamba4-sulfanyl]-5-(trifluoromethyl)aniline
0.00012 - 0.0621
2,4-bis[amino(dihydroxy)-lambda4-sulfanyl]-5-chloroaniline
0.212
2,5-difluorophenol
-
at pH 7.5 and 20°C
0.000823 - 0.00967
2,6-dimethoxybenzoic acid
0.000084 - 0.158
2-(3-chloro-4-hydroxyphenyl)-N-(2-methoxyethyl)acetamide
0.000091 - 0.0098
2-(3-chloro-4-hydroxyphenyl)-N-(2-phenylethyl)acetamide
0.000079 - 0.0119
2-(3-chloro-4-hydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
0.000087 - 0.0112
2-(3-chloro-4-hydroxyphenyl)-N-[2-(3-methoxyphenyl)ethyl]acetamide
0.000018 - 0.0007
2-(3-chloro-4-hydroxyphenyl)-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
0.000106 - 0.237
2-(3-chloro-4-hydroxyphenyl)acetamide
0.00232 - 0.0054
2-(3-hydroxyphenyl)ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
0.0023 - 0.00609
2-(3-hydroxyphenyl)ethyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate
0.0000009 - 45
2-(3-methoxypropyl)-4-(methylamino)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
0.000081 - 0.309
2-(4-hydroxyphenyl)acetamide
0.0032 - 0.00726
2-(4-hydroxyphenyl)ethyl (2E)-3-(3-hydroperoxy-4-hydroxyphenyl)prop-2-enoate
0.00187 - 0.00513
2-(4-hydroxyphenyl)ethyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate
0.001436
2-(7-methoxy-2-oxo-2H-chromen-4-yl)-N-(2-sulfamoylphenyl)acetamide
-
-
0.004578
2-(7-methoxy-2-oxo-2H-chromen-4-yl)-N-(3-sulfamoylphenyl)acetamide
-
-
0.00097
2-(7-methoxy-2-oxo-2H-chromen-4-yl)-N-(4-sulfamoylphenyl)acetamide
-
-
0.0000072 - 1.4
2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide
0.000893 - 0.0128
2-(hydroxymethyl)-4-nitro-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide
0.0000502 - 0.000134
2-(hydroxymethyl)-4-nitro-N-[2-(4-sulfamoylphenyl)ethyl]benzenesulfonamide
0.00001 - 0.806
2-(phenylethynyl)benzenesulfonamide
0.0000315 - 0.0000639
2-adamantylethyl 7-methoxy-2-oxo-2H-chromene-8-carboxylate
0.00595
2-amino-1-benzothiophen-3(2H)-one 1,1-dioxide
-
wild-type, pH 7.5, 20°C
0.000091
2-amino-pyrimidin-4-yl-sulfanilamide
-
at 20°C, pH 8.3, in 20 mM Tris-HCl and 20 mM NaCl
0.00044 - 0.887
2-aminobenzenesulfonamide
0.005874
2-bromo-benzenesulfonamide
-
pH 8.5, 35°C
0.0674
2-bromobenzene-1-sulfonamide
-
pH 7.4, 25°C, inhibition of 4-nitrophenyl acetate hydrolysis activity
0.0031 - 1
2-coumaric acid
0.00109 - 1.995
2-hydrazinobenzenesulfonamide
0.0000521 - 0.00885
2-hydrazinylbenzenesulfonamide
0.0000879 - 0.1
2-methoxy-N-[(1-methylpyrrolidin-2-yl)methyl]-5-sulfamoylbenzamide
0.000369
2-methyl-N-(4-sulfamoylphenyl)propanamide
-
pH 7.5, 20°C
0.00000061 - 0.36
2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide
0.000012 - 0.0012
2-N-(4-sulfamoylphenyl)-thioformyl-L-Ala
0.000006 - 0.000027
2-N-(4-sulfamoylphenyl)-thioformyl-L-Asn
0.000009 - 0.00004
2-N-(4-sulfamoylphenyl)-thioformyl-L-Gln
0.000004 - 0.000022
2-N-(4-sulfamoylphenyl)-thioformyl-L-Ile
0.000005 - 0.000021
2-N-(4-sulfamoylphenyl)-thioformyl-L-Leu
0.000004 - 0.000027
2-N-(4-sulfamoylphenyl)-thioformyl-L-Met
0.000006 - 0.00003
2-N-(4-sulfamoylphenyl)-thioformyl-L-Phe
0.000025 - 0.00011
2-N-(4-sulfamoylphenyl)-thioformyl-L-Pro
0.000011 - 0.000047
2-N-(4-sulfamoylphenyl)-thioformyl-L-Trp
0.000005 - 0.000023
2-N-(4-sulfamoylphenyl)-thioformyl-L-Val
0.00004 - 0.000063
2-naphthyl sulfamate
0.000103
2-naphthylsulfamate
-
pH 7.4, 25°C, hCA I
0.0012 - 0.009
2-naphthylsulfonylsulfamic acid
0.0038 - 0.0447
2-oxo-2H-chromene-3-carboxylic acid
0.000047 - 0.009
2-oxo-2H-thiochromene-3-carboxylic acid
0.01851
2-oxo-N-(2-sulfamoylphenyl)-2H-chromene-3-carboxamide
-
-
0.025
2-oxo-N-(3-sulfamoylphenyl)-2H-chromene-3-carboxamide
-
-
0.005048
2-oxo-N-(4-sulfamoylbenzyl)-2H-chromene-3-carboxamide
-
-
0.005816
2-oxo-N-(4-sulfamoylphenyl)-2H-chromene-3-carboxamide
-
-
0.01317
2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2H-chromene-3-carboxamide
-
-
0.0000011 - 0.0041
2-phenylethyl sulfamate
0.001992
2-[(diphenylcarbamoyl)amino]benzenesulfonamide
-
-
0.00395 - 0.00803
2-[3-[2-(3-hydroxyphenyl)ethoxy]phenyl]ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
0.0051 - 0.00713
2-[4-[2-(4-hydroxyphenyl)ethoxy]phenyl]ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
0.0031 - 0.5
2H-chromen-2-one
0.000147
3,3-dimethyl-N-(4-sulfamoylphenyl)butanamide
-
pH 7.5, 20°C
0.0000048 - 0.00083
3,4,6-tri-O-acetyl-2-deoxy-N-sulfamoyl-beta-D-arabino-hexopyranosylamine
0.0000078 - 0.00083
3,4,6-tri-O-acetyl-2-deoxy-N-sulfamoyl-beta-D-lyxo-hexopyranosylamine
0.000006 - 0.00151
3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.00047 - 0.00445
3,4-dihydroxybenzoic acid
0.00618 - 0.00825
3,4-dimethoxybenzoic acid
0.000957 - 0.00631
3,5-dichloro-2-hydroxybenzene-1-sulfonamide
0.009135 - 0.009433
3,5-dichloro-2-hydroxybenzenesulfonamide
0.0113
3,5-difluorophenol
-
at pH 7.5 and 20°C
0.000367 - 0.00441
3,5-Dihydroxybenzoic acid
0.000152 - 0.00793
3-(4-sulfamoylphenyl)propanoic acid
0.000057 - 0.00051
3-(methylsulfanyl)-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
0.0000013 - 0.000087
3-(phenylethynyl)benzenesulfonamide
0.000581 - 0.00063
3-aminobenzene-1-sulfonamide
0.00596 - 0.02546
3-aminobenzenesulfonamide
0.000977
3-bromo-4-amino-benzenesulfonamide
-
at 20°C, pH 8.3
0.000605
3-chloro-4-amino-benzenesulfonamide
-
at 20°C, pH 8.3
0.000033 - 0.001
3-chloro-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
0.00057 - 0.00462
3-chloropropyl sulfamate
0.000809
3-fluoro-4-amino-benzenesulfonamide
-
at 20°C, pH 8.3
0.000353 - 0.00453
3-Hydroxybenzoic acid
0.000711
3-iodo-4-amino-benzenesulfonamide
-
at 20°C, pH 8.3
0.0000019
3-methylphenyl sulfamate
-
pH 7.4, 25°C, hCA II
0.0000038
3-methylphenylsulfamate
-
pH 7.4, 25°C, hCA I
10.57 - 11.42
3-methylsalicylic acid
0.000009 - 0.00021
3-morpholin-4-yl-4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
0.000012 - 0.416
3-phenylpropanenitrile
0.000001 - 0.00214
3-[(3-fluorophenyl)ethynyl]benzenesulfonamide
0.0000017 - 0.006315
3-[(3-methoxyphenyl)ethynyl]benzenesulfonamide
0.0000011 - 0.00171
3-[(4-methylphenyl)ethynyl]benzenesulfonamide
0.00001 - 0.00365
3-[(anilinocarbonyl)amino]benzenesulfonamide
0.000156
3-[(phenylcarbamoyl)amino]benzenesulfonamide
-
pH 7.5, 20°C
0.000006 - 0.0007
3-[(sulfoamino)sulfonyl]benzoic acid
0.00017 - 0.0143
3-[amino(dihydroxy)-lambda4-sulfanyl]aniline
0.00007 - 0.001
3-[[(aminosulfonyl)amino]sulfonyl]benzoic acid
0.0000047 - 0.01117
4,4'-thiodipyridine-3-sulfonamide
0.000069 - 0.368
4,4'-[(1R,2R,3S,4S)-3,4-dimethylcyclobutane-1,2-diyl]bis(2-methoxyphenol)
0.000079 - 0.354
4,4'-[(1R,2S,3R,4S)-3,4-dimethylcyclobutane-1,2-diyl]bis(2-methoxyphenol)
0.000071 - 0.307
4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol)
0.000021 - 0.015
4,5-dichloro-benzene-1,3-disulfonamide
0.0000371 - 0.00089
4,5-dichlorobenzene-1,3-disulfonamide
0.00545 - 0.01485
4,6-dinitrosalicylic acid
0.0000719 - 0.000834
4-(1,1-dioxido-1,2-thiazinan-2-yl)benzenesulfonamide
0.000132 - 0.0189
4-(1,1-dioxo-1lambda6,2-thiazinan-2-yl)benzene-1-sulfonamide
0.0000051 - 0.00667
4-(1,3,4-thiadiazol-2-ylthio)pyridine-3-sulfonamide
0.0000042 - 0.00653
4-(1-methyl-5-tetrazolylthio)pyridine-3-sulfonamide
0.000016
4-(2-([(4-sulfamoylphenyl)carbamothioyl]amino)ethyl)benzenesulfonamide
-
pH 7.5, 20°C
0.0000151 - 0.003887
4-(2-amino-pyrimidin-4-yl)-benzenesulfonamide
0.0096
4-(2-aminoethyl) benzenesulfonamide
-
pH 8.5, 35°C
0.000758 - 0.0064
4-(2-aminoethyl)benzene-1-sulfonamide
0.000079 - 1.6
4-(2-aminoethyl)benzenesulfonamide
0.000726 - 0.000904
4-(2-hydroxyethyl)benzene-1-sulfonamide
0.0000567 - 1.187
4-(2-hydroxyethyl)benzenesulfonamide
0.000101 - 0.43
4-(2-hydroxyethyl)phenol
0.0000067 - 0.01032
4-(2-methyl-8-quinolinoxy)-3-pyridinesulfonamide
0.0000012 - 0.0035
4-(2-methylphenyl)benzene-1-sulfonamide
0.0000053
4-(2-phenylacetamido)-3-bromobenzenesulfonamide
-
isoform CA VII
0.0000069
4-(2-phenylacetamido)-3-chlorobenzenesulfonamide
-
isoform CA VII
0.0000054
4-(2-phenylacetamido)-3-fluorobenzenesulfonamide
-
isoform CA VII
0.0000047
4-(2-phenylacetamido)benzenesulfonamide
-
isoform CA VII
0.0000055
4-(2-phenylacetamidoethyl)benzenesulfonamide
-
isoform CA VII
0.0000068
4-(2-phenylacetamidomethyl)benzenesulfonamide
-
isoform CA VII
0.0000063 - 0.00832
4-(2-propynylthio)pyridine-3-sulfonamide
0.0000077
4-(2-pyridin-2-ylacetamido)benzenesulfonamide
-
isoform CA VII
0.0000079
4-(2-pyridin-4-ylacetamido)benzenesulfonamide
-
isoform CA VII
0.0000085
4-(2-pyridin-4-ylacetamidoethyl)benzenesulfonamide
-
isoform CA VII
0.000621
4-(2-[(phenylcarbamothioyl)amino]ethyl)benzenesulfonamide
-
pH 7.5, 20°C
0.000238
4-(2-[(phenylcarbamoyl)amino]ethyl)benzenesulfonamide
-
pH 7.5, 20°C
0.00018
4-(3,4-dichlorophenylureido)thioureido-benzenesulfonamide
-
-
0.0000006 - 0.0012
4-(3-formylphenyl)benzene-1-sulfonamide
0.0000002 - 0.00076
4-(3-quinolinyl)benzene-1-sulfonamide
0.025
4-(3-[[(1E)-(1-methyl-1H-imidazol-2-yl)methylidene]amino]propyl)benzenesulfonamide
-
-
0.00003 - 0.000638
4-(4'-dimethylaminophenyl)diazenylbenzenesulfonamide
0.000312 - 0.000752
4-(4'-hydroxyphenyl)diazenylbenzene-N,N-dimethylsulfonamide
0.000277 - 0.000706
4-(4'-hydroxyphenyl)diazenylbenzene-N-methylsulfonamide
0.000046 - 0.000665
4-(4'-hydroxyphenyl)diazenylbenzenesulfonamide
0.000863 - 0.0042
4-(4'-methoxyphenyl)diazenylbenzene-N,N-dimethylsulfonamide
0.0000063 - 0.00664
4-(4-cyanophenoxy)-3-pyridinesulfonamide
0.0000069 - 0.00916
4-(4-fluorophenoxy)-3-pyridinesulfonamide
0.000624
4-(4-sulfanilyl-aminoethyl)-benzenesulfonamide
-
at 20°C, pH 8.3
0.000971
4-(4-sulfanilyl-aminomethyl)-benzenesulfonamide
-
at 20°C, pH 8.3
0.0000078 - 0.0103
4-(5-methyl-2-pyrazolino)-3-pyridinesulfonamide
0.000226 - 0.0164
4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide
0.0000897 - 0.0315
4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide
0.00000216 - 0.00884
4-(6-nitrobenzothiazol-2-ylthio)pyridine-3-sulfonamide
0.000012 - 0.00886
4-(allylamino)-3-pyridinesulfonamide
0.000904 - 0.00365
4-(aminomethyl)benzene-1-sulfonamide
0.0000825 - 0.681
4-(aminomethyl)benzenesulfonamide
0.000012 - 1.06
4-(aminosulfonyl)-N-[2-[4-(aminosulfonyl)phenyl]ethyl]benzamide
0.000887 - 0.0113
4-(aminosulfonyl)benzoic acid
0.002102
4-(carbamothioylamino)benzenesulfonamide
-
-
0.0000118 - 0.00951
4-(carbamoylmethylthio)pyridine-3-sulfonamide
0.00044
4-(carboxyethyl)-benzenesulfonamide
-
at 20°C, pH 8.3
0.0000117 - 0.01171
4-(cyanomethylthio)pyridine-3-sulfonamide
0.000704 - 0.0063
4-(hydroxymethyl)benzene-1-sulfonamide
0.0000545 - 26
4-(hydroxymethyl)benzenesulfonamide
0.0000089 - 0.000562
4-(methylhydrazino)-3-pyridinesulfonamide
0.0000075 - 0.00762
4-(N-oxide-2-pyridylthio)pyridine-3-sulfonamide
0.0000094 - 0.00565
4-(phenylethynyl)benzenesulfonamide
0.0000068 - 0.01032
4-(quinolinoxy)-3-pyridinesulfonamide
0.025
4-([(1E)-[4-(dimethylamino)phenyl]methylidene]amino)benzenesulfonamide
-
-
0.000679
4-([(phenylcarbamothioyl)amino]methyl)benzenesulfonamide
-
pH 7.5, 20°C
0.00025
4-([[(1Z)-(2-chlorophenyl)methylidene]amino]methyl)benzenesulfonamide
-
-
0.002997
4-([[(diethyl-l5-azanylidyne)methyl]disulfanyl]amino)benzenesulfonamide
-
-
0.0025 - 0.01
4-acetyl-N-(aminosulfonyl)benzenesulfonamide
0.000018 - 0.000045
4-acetylamidophenyl sulfamate
0.00006 - 0.0107
4-amino-3,5-dibromobenzenesulfonamide
0.000084 - 0.000879
4-amino-3,5-diiodobenzenesulfonamide
0.00852
4-amino-3,bromobenzenesulfonamide
-
pH 7.5, 20°C
0.00502 - 0.00544
4-amino-3-bromobenzene-1-sulfonamide
0.000083 - 0.00842
4-amino-3-bromobenzenesulfonamide
0.006175 - 0.0113
4-amino-3-chlorobenzene-1-sulfonamide
0.000062 - 0.71
4-amino-3-chlorobenzenesulfonamide
0.019
4-amino-3-fluoro-5-iodobenzenesulfonamide
20°C, pH 7.5
0.005545 - 0.0102
4-amino-3-fluorobenzene-1-sulfonamide
0.00006 - 2.075
4-amino-3-fluorobenzenesulfonamide
0.000072 - 0.00771
4-amino-3-iodobenzenesulfonamide
0.0000629 - 1.276
4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
0.0003
4-amino-6-chloro-benzene-1,3-disulfonamide
-
at 20°C, pH 8.3
0.0000453 - 0.0736
4-amino-6-chlorobenzene-1,3-disulfonamide
0.000968
4-amino-6-trifluoromethyl-benzene-1,3-disulfonamide
-
at 20°C, pH 8.3
0.000765
4-amino-benzenesulfonamide
-
at 20°C, pH 8.3
0.0303
4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzene-1-sulfonamide
-
pH 7.4, 25°C, inhibition of 4-nitrophenyl acetate hydrolysis activity
0.0000298 - 0.0524
4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide
0.006705 - 0.0124
4-amino-N-(4-sulfamoylcyclopenta-1,3-dien-1-yl)benzene-1-sulfonamide
0.00814 - 0.015
4-amino-N-(4-sulfamoylphenyl)benzene-1-sulfonamide
0.0000042 - 0.000365
4-amino-N-(4-sulfamoylphenyl)benzenesulfonamide
0.0216
4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide
-
pH 7.4, 25°C, inhibition of 4-nitrophenyl acetate hydrolysis activity
0.09125
4-amino-N-carbamimidoylbenzene-1-sulfonamide
-
pH 7.4, 25°C, inhibition of 4-nitrophenyl acetate hydrolysis activity
0.0146 - 0.0187
4-amino-N-[(4-sulfamoylphenyl)methyl]benzene-1-sulfonamide
-
0.0084 - 0.0212
4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide
0.000016 - 0.000853
4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzenesulfonamide
0.000024 - 0.14
4-amino-N-[2-[4-(aminosulfonyl)phenyl]ethyl]benzenesulfonamide
0.000055 - 0.114
4-amino-N-[4-(aminosulfonyl)benzyl]benzenesulfonamide
0.000808 - 0.0058
4-aminobenzene-1-sulfonamide
0.000037 - 0.988
4-Aminobenzenesulfonamide
0.001394
4-aminoethyl-benzenesulfonamide
-
at 20°C, pH 8.3
0.0000032 - 0.0029
4-aminoethylbenzenesulfonamide
0.01849
4-aminomethyl-benzenesulfonamide
-
at 20°C, pH 8.3
0.335
4-Aminophenol
-
at pH 7.5 and 20°C
0.24 - 1.23
4-aminosalicylic acid
0.0000065 - 0.00909
4-benzythiopyridine-3-sulfonamide
0.00005 - 0.000113
4-biphenyl sulfamate
0.000068 - 0.00065
4-bromobenzenesulfonamide
0.0000073 - 0.000374
4-bromophenyl sulfamate
0.000484
4-carboxy-benzenesulfonamide
-
at 20°C, pH 8.3
0.000079
4-chloro-6-[(phenylcarbamoyl)amino]benzene-1,3-disulfonamide
-
pH 7.5, 20°C
0.08275
4-chlorobenzene-1-sulfonamide
-
pH 7.4, 25°C, inhibition of 4-nitrophenyl acetate hydrolysis activity
0.0000175 - 0.000053
4-chlorobenzenesulfonamide
0.0000046 - 0.000215
4-chlorophenyl sulfamate
0.00269 - 0.00605
4-coumaric acid
0.000041 - 0.00048
4-cyanophenyl sulfamate
0.000149
4-cyanophenylsulfamate
-
pH 7.4, 25°C, hCA II
0.0000059 - 0.0061
4-ethoxy-3-pyridinesulfonamide
0.0000051 - 0.00108
4-ethynylbenzenesulfonamide
0.0000049 - 0.00791
4-hydrazino-3-pyridinesulfonamide
0.001275 - 0.00954
4-hydrazinobenzenesulfonamide
0.000125 - 0.006081
4-hydrazinylbenzenesulfonamide
0.00289 - 0.00449
4-hydroxybenzene-1-sulfonamide
0.000088 - 0.07388
4-hydroxybenzenesulfonamide
0.00932
4-hydroxybenzoic acid
-
at pH 7.5 and 20°C
0.434
4-Hydroxybenzonitrile
-
at pH 7.5 and 20°C
0.000878
4-hydroxyethyl-benzenesulfonamide
-
at 20°C, pH 8.3
0.000623
4-hydroxymethyl-benzenesulfonamide
-
at 20°C, pH 8.3
0.00007 - 0.000081
4-iodobenzenesulfonamide
0.0000038 - 0.000023
4-iodophenyl sulfamate
0.0000057 - 0.00734
4-methoxy-3-pyridinesulfonamide
0.000033 - 0.000034
4-methoxyphenyl sulfamate
0.000815
4-methyl-5-imino-1,3,4-thiadiazoline-2-sulfonamide
-
at 20°C, pH 8.3
0.00115
4-methyl-benzenesulfonamide
-
at 20°C, pH 8.3
0.00312 - 0.0075
4-methylbenzene-1-sulfonamide
0.000516 - 0.00799
4-methylbenzenesulfonamide
0.000059
4-methylphenyl sulfamate
-
pH 7.4, 25°C, hCA IX
0.0000067 - 0.00983
4-methylthiopyridine-3-sulfonamide
0.000036
4-nitrophenyl sulfamate
-
pH 7.4, 25°C, hCA IX
0.00004
4-nitrophenylsulfamate
-
pH 7.4, 25°C, hCA I
0.000051 - 0.000115
4-phenoxyphenyl sulfamate
0.0000002 - 0.000093
4-phenylbenzene-1-sulfonamide
0.003053
4-sulfamoyl-N-(4-sulfamoylphenyl)benzamide
-
-
0.000015 - 0.000902
4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamide
0.0000596 - 0.084
4-sulfamoylbenzoic acid
0.48 - 1.06
4-sulfosalicylic acid
0.0000029 - 0.000043
4-t-butylphenyl sulfamate
0.000054 - 0.000138
4-trifluoromethylphenyl sulfamate
0.00525 - 0.006225
4-[(2-aminopyrimidin-4-yl)amino]benzene-1-sulfonamide
0.000021 - 2.633
4-[(2-aminopyrimidin-4-yl)amino]benzenesulfonamide
0.0000056 - 0.001442
4-[(2R)-2-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
0.0000754 - 0.0004219
4-[(2S)-2-benzylpiperazine-1-carbonyl]benzene-1-sulfonamide
0.000067
4-[(3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)amino]benzenesulfonamide
at 20°C, pH 8.3 in 20 mM Tris-HCl buffer and 20 mM NaCl
0.0000058 - 0.000076
4-[(3-fluorophenyl)ethynyl]benzenesulfonamide
0.0000016 - 0.00529
4-[(3-hydroxyphenyl)ethynyl]benzenesulfonamide
0.0000012 - 0.00489
4-[(3-methoxyphenyl)ethynyl]benzenesulfonamide
0.000068 - 0.00559
4-[(4-methylphenyl)ethynyl]benzenesulfonamide
0.000037 - 0.0026
4-[(acetyloxy)amino]-N-[4-(aminosulfonyl)phenyl]benzenesulfonamide
0.000069 - 0.00043
4-[(anilinocarbonyl)amino]-6-chlorobenzene-1,3-disulfonamide
0.000033 - 0.00125
4-[(methylsulfonyl)amino]benzenesulfonamide
0.000041 - 0.00243
4-[(phenylsulfonyl)amino]benzenesulfonamide
0.000008 - 0.0005
4-[(sulfoamino)sulfonyl]benzoic acid
0.025
4-[([(1Z)-[4-(dimethylamino)phenyl]methylidene]amino)methyl]benzenesulfonamide
-
-
0.008392
4-[([[(diethyl-l5-azanylidyne)methyl]disulfanyl]amino)methyl]benzenesulfonamide
-
-
0.0000076
4-[2-(2-thienyl)acetamidoethyl]benzenesulfonamide
-
isoform CA VII
0.0000071
4-[2-(2-thienyl)acetamidomethyl]benzenesulfonamide
-
isoform CA VII
0.0000072
4-[2-(2-thienyl)acetamido]-3-bromobenzenesulfonamide
-
isoform CA VII
0.0000069
4-[2-(2-thienyl)acetamido]-3-chlorobenzenesulfonamide
-
isoform CA VII
0.000007
4-[2-(2-thienyl)acetamido]-3-fluorobenzenesulfonamide
-
isoform CA VII
0.0000062
4-[2-(2-thienyl)acetamido]benzenesulfonamide
-
isoform CA VII
0.0000075 - 0.00152
4-[2-(4-sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide
0.004057
4-[2-[(2-oxo-2H-chromen-3-yl)carbonyl]hydrazino]benzenesulfonamide
-
-
0.003506
4-[2-[(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl]hydrazino]benzenesulfonamide
-
-
0.000021 - 0.00298
4-[2-[(anilinocarbonothioyl)amino]ethyl]benzenesulfonamide
0.000013 - 0.00026
4-[2-[(anilinocarbonyl)amino]ethyl]benzenesulfonamide
0.000003 - 0.00303
4-[2-[([[4-(aminosulfonyl)phenyl]amino]carbonothioyl)amino]ethyl]benzenesulfonamide
0.025
4-[3-([(1E)-[4-(dimethylamino)phenyl]methylidene]amino)propyl]benzenesulfonamide
-
-
0.0000016 - 0.000005
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4',6'-tetra-O-acetyl-alpha-D-mannopyranosyl)-1H-1,2,3-triazole
0.0000087 - 0.0043
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4',6'-tetra-O-acetyl-beta-D-galactopyranosyl)-1H-1,2,3-triazole
0.0000091 - 0.0044
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4',6'-tetra-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole
0.0000082 - 0.000134
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4'-tri-O-acetyl-alpha-D-arabinopyranosyl)-1H-1,2,3-triazole
0.0000099 - 0.00013
4-[4-(aminosulfonyl)phenyl]-1-(2',3',4'-tri-O-acetyl-beta-D-glucuronic acid methyl ester)-1H-1,2,3-triazole
0.0001 - 0.0053
4-[4-(aminosulfonyl)phenyl]-1-(2',3',5'-tri-O-benzoyl-beta-D-ribofuranosyl)-1H-1,2,3-triazole
0.000101 - 0.005
4-[4-(aminosulfonyl)phenyl]-1-(2'-acetamido-2'-deoxy'-3',4',6'-tri-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole
0.000085
4-[4-(aminosulfonyl)phenyl]-1-(2'-acetamido-2'-deoxy-beta-D-glucopyranosyl)-1H-1,2,3-triazole
-
isozyme CA IX, in 10 mM HEPES (pH 7.5), 0.1 M NaClO4, at 20°C
0.0000023 - 0.000028
4-[4-(aminosulfonyl)phenyl]-1-(alpha-D-arabinopyranosyl)-1H-1,2,3-triazole
0.0000028 - 0.0000076
4-[4-(aminosulfonyl)phenyl]-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole
0.0000093 - 0.00012
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-galactopyranosyl)-1H-1,2,3-triazole
0.0000089 - 0.00038
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-glucopyranosyl)-1H-1,2,3-triazole
0.0000084 - 0.00056
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-glucuronic acid methyl ester)-1H-1,2,3-triazole
0.00013 - 0.005
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-maltopyranosyl)-1H-1,2,3-triazole
0.0000075 - 0.0043
4-[4-(aminosulfonyl)phenyl]-1-(beta-D-ribofuranosyl)-1H-1,2,3-triazole
0.00012 - 0.0025
4-[4-(aminosulfonyl)phenyl]-1-(hepta-O-acetyl-beta-D-maltopyranosyl)-1H-1,2,3-triazole
0.000021 - 0.0348
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
0.00028 - 0.077
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-bromoaniline
0.00014 - 0.111
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-chloroaniline
0.00097 - 0.0534
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-fluoroaniline
0.00028 - 0.098
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-iodoaniline
0.0000046 - 0.0089
4-[N'-(1,1-dioxopyrido[4,3-e]-1,4,2-dithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
0.0000034 - 0.0000923
4-[N'-(6-chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
0.0000081
4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
-
isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C
0.0000058 - 0.000101
4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazyno]-3-pyridinesulfonamide
0.004162
4-[[(1Z)-(1-bromonaphthalen-2-yl)methylidene]amino]benzenesulfonamide
-
-
0.000019
4-[[(2R,3R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
at 20°C, pH 8.3 in 20 mM Tris-HCl buffer and 20 mM NaCl
0.000028
4-[[(2R,5S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
at 20°C, pH 8.3 in 20 mM Tris-HCl buffer and 20 mM NaCl
0.00558
4-[[(3,4-dichlorophenyl)carbamoyl]amino]benzenesulfonamide
-
-
0.000103
4-[[(3R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
at 20°C, pH 8.3 in 20 mM Tris-HCl buffer and 20 mM NaCl
0.000065
4-[[(3R,4R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
at 20°C, pH 8.3 in 20 mM Tris-HCl buffer and 20 mM NaCl
0.0000089
4-[[(4R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
at 20°C, pH 8.3 in 20 mM Tris-HCl buffer and 20 mM NaCl
0.0000092
4-[[(5R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
at 20°C, pH 8.3 in 20 mM Tris-HCl buffer and 20 mM NaCl
0.00006 - 0.0009
4-[[(aminosulfonyl)amino]sulfonyl]benzoic acid
0.000018 - 0.00297
4-[[(anilinocarbonothioyl)amino]methyl]benzenesulfonamide
0.01604
4-[[(diphenylcarbamoyl)amino]methyl]benzenesulfonamide
-
-
0.00004 - 0.000465
4-[[(phenylsulfonyl)amino]methyl]benzenesulfonamide
0.00011
4-[[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]amino]benzenesulfonamide
at 20°C, pH 8.3 in 20 mM Tris-HCl buffer and 20 mM NaCl
0.00046 - 0.0021
4H-[1,2,3]thiadiazolo[3,4-a]benzimidazole-7-sulfonamide
0.0001035 - 0.000236
5,6-diamino-1,3-dimethyluracil
0.000033 - 0.0146
5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
0.0000061
5-(2-phenylacetamido)-1,3,4-thiadiazole-2-sulfonamide
-
isoform CA VII
0.00000059 - 0.035
5-(3-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
0.000012
5-(formylamino)-1,3,4-thiadiazole-2-sulfonamide
-
wild-type, pH 7.5, 20°C
0.04951
5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione
pH 7.4, temperature not specified in the publication
0.04185
5-([(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino)-1,3,4-thiadiazole-2-sulfonamide
-
pH 7.5, 20°C
0.0000885 - 0.04188
5-([(4-aminophenyl)sulfonyl]amino)-1,3,4-thiadiazole-2-sulfonamide
0.0000019
5-([(4-bromophenyl)sulfonyl]amino)-1,3,4-thiadiazole-2-sulfonamide
-
pH 7.5, 20°C
0.0000035
5-([(4-nitrophenyl)sulfonyl]amino)-1,3,4-thiadiazole-2-sulfonamide
-
pH 7.5, 20°C
0.000049 - 0.236
5-acetamido-1,3,4-thiadiazole-2-sulfonamide
0.0000235 - 0.148
5-amino-1,3,4-thiadiazole-2-sulfonamide
0.01083 - 0.02888
5-bromo-1-(4-methylbenzene-1-sulfonyl)pyrimidine-2,4(1H,3H)-dione
0.428 - 0.645
5-bromo-1-(methanesulfonyl)pyrimidine-2,4(1H,3H)-dione
0.00127 - 0.00416
5-chlorosalicylic acid
0.0000112 - 0.198
5-imino-4-methyl-4,5-dihydro-1,3,4-thiadiazole-2-sulfonamide
0.000105
5-pentylresorcinyl sulfamate
-
pH 7.4, 25°C, hCA I
0.000043 - 0.000076
5-pentylresorcinylsulfamate
0.77 - 1.92
5-sulfosalicylic acid
0.00133 - 0.0112
5-[(benzenesulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
0.0000042 - 0.000482
5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
0.0000069
5-[2-(2-thienyl)acetamido]-1,3,4-thiadiazole-2-sulfonamide
-
isoform CA VII
0.000186 - 0.0805
5-[[(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
0.000186 - 0.000663
5-[[(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino]-4,5-dihydro-1,3,4-thiadiazole-2-sulfonamide
0.0000276 - 0.0181
5-[[(4-aminophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
0.0000033 - 0.000062
5-[[(4-bromophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
0.0000019 - 0.000072
5-[[(4-nitrophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
0.002583
5-[[(pentafluorophenyl)sulfonyl]amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
0.000315
5-[[(phenylcarbamoyl)carbamothioyl]amino]-1,3,4-thiadiazole-2-sulfonamide
-
-
0.0000094 - 0.0028
6,7-dimethoxy-1-ethyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.000302 - 0.235
6,7-dimethoxy-1-isopropyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.0000095 - 0.00641
6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.00386 - 0.0157
6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.0000763 - 0.002754
6,7-dimethoxy-1-propyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
0.000059 - 0.5
6-((1S)-hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one
0.0000486 - 0.000078
6-(1-hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one
0.0037 - 0.0097
6-(aminomethyl)-2H-chromen-2-one
0.0043 - 0.0445
6-(hydroxymethyl)-2-oxo-2H-chromene-3-carboxylic acid
0.000093 - 0.0324
6-(hydroxymethyl)-2H-chromen-2-one
0.0777
6-acetyl-7-adamantylethoxy-2H-chromen-2-one
-
inhibition of isozyme hCA XII, pH not specified in the publication, temperature not specified in the publication
0.0074
6-acetyl-7-ethoxy-2H-chromen-2-one
-
inhibition of isozyme hCA IX, pH not specified in the publication, temperature not specified in the publication
0.00803
6-acetyl-7-hydroxy-2H-chromen-2-one
-
inhibition of isozyme hCA IX, pH not specified in the publication, temperature not specified in the publication
0.00654 - 0.0078
6-acetyl-7-methoxy-2H-chromen-2-one
0.00758
6-acetyl-7-propoxy-2H-chromen-2-one
-
inhibition of isozyme hCA IX, pH not specified in the publication, temperature not specified in the publication
0.000085 - 0.0001715
6-amino-1,3-dimethyluracil
0.0196 - 0.0683
6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda6,2,4-benzothiadiazine-7-sulfonamide
0.000153
6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~,2,4-benzothiadiazine-7-sulfonamide
pH 7.5, 22°C, inhibition of CO2 hydration activity of PfCA38
-
0.0000502 - 0.000394
6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
0.000021 - 0.0084
6-chloro-4-amino-benzene-1,3-disulfonamide
0.0000073 - 0.000019
6-deoxy-N-(4-sulfamoylphenyl)-alpha-L-mannopyranosylamine
0.00314 - 0.5
6-deoxy-N-sulfamoyl-alpha-L-glucopyranosylamine
0.00000069 - 0.038
6-ethoxy-1,3-benzothiazole-2-sulfonamide
0.000025 - 0.000084
6-ethoxy-2-benzo-thiazolesulfonamide
0.0000047 - 0.000866
6-hydroxy-1,3-benzothiazole-2-sulfonamide
0.0049 - 0.0396
6-methoxy-2-oxo-2H-chromene-3-carboxylic acid
0.0056 - 0.0425
6-methyl-2-oxo-2H-chromene-3-carboxylic acid
0.0000035 - 8
6-methyl-4-(methylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
0.05776
6-methylpyrimidine-2,4(1H,3H)-dione
pH 7.4, temperature not specified in the publication
0.00002 - 0.0094
6-trifluoromethyl-4-aminobenzene-1,3-disulfonamide
0.000012 - 0.7
667-coumate
0.000243 - 0.0694
7-(2-phenylethoxy)-2H-chromen-2-one
0.000224 - 0.0651
7-(benzyloxy)-2H-chromen-2-one
0.000213 - 0.0764
7-butoxy-2H-chromen-2-one
0.0016 - 0.0609
7-ethoxy-2H-chromen-2-one
0.0000332 - 0.0000467
7-ethoxy-8-propanoyl-2H-chromen-2-one
0.000093 - 0.201
7-hydroxy-1-methoxy-3-methyl-9-oxo-9,9a-dihydro-4aH-xanthene-8-carboxylic acid
0.000094 - 0.374
7-hydroxy-3-(hydroxymethyl)-1-methoxy-9-oxo-9,9a-dihydro-4aH-xanthene-8-carboxylic acid
0.008015
7-hydroxy-6-propanoyl-2H-chromen-2-one
-
inhibition of isozyme hCA IX, pH not specified in the publication, temperature not specified in the publication
0.0000582 - 0.0000617
7-hydroxy-8-propanoyl-2H-chromen-2-one
0.000099 - 0.5
7-methoxy-2-oxo-2H-chromene-4-carboxylic acid
0.000066 - 0.5
7-methoxy-2H-chromen-2-one
0.0000263 - 0.0000378
7-methoxy-8-propanoyl-2H-chromen-2-one
0.000023 - 0.0041
7-oxodehydroepiandrosterone sulfamate
0.0033 - 0.145
7-propoxy-2H-chromen-2-one
0.000013 - 0.004
7alpha-hydroxyepiandrosterone sulfamate
0.0000224 - 0.0000723
8-acetyl-7-(benzyloxy)-2H-chromen-2-one
0.0000088 - 0.0000612
8-acetyl-7-butoxy-2H-chromen-2-one
0.000001 - 0.0000708
8-acetyl-7-ethoxy-2H-chromen-2-one
0.0000619 - 0.000073
8-acetyl-7-hydroxy-2H-chromen-2-one
0.0000609 - 0.0000783
8-acetyl-7-methoxy-2H-chromen-2-one
0.00000098 - 0.0000567
8-acetyl-7-propoxy-2H-chromen-2-one
0.001 - 0.0301
8-methoxy-2-oxo-2H-chromene-3-carboxylic acid
0.0000384 - 0.0000502
8-propanoyl-7-propoxy-2H-chromen-2-one
0.0000003 - 0.3
acetazolamide
3.66 - 7.53
Acetylsalicylic acid
1.36 - 193.9
Ag+
0.000042
aminobenzolamide
-
at 20°C, pH 8.3
0.00000064 - 0.000072
azetazolamide
0.0085 - 27.9
azide
4.7 - 8
B4O72-
0.0102 - 4.003
benzene-1,2-diol
0.385 - 0.795
benzene-1,3-diol
0.00514 - 0.0638
benzene-1,3-disulfonamide
0.0106
benzene-1,4-diol
-
at pH 7.5 and 20°C
0.000219 - 0.1
benzenesulfonamide
0.000007 - 0.0143
benzolamide
0.0102 - 4.1
Benzyl (2-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-2-oxoethyl)carbamate
0.0868
benzyl (2-((4-methylbenzo[d]thiazol-2-yl)amino)-2-oxoethyl)carbamate
pH 7.5, 22°C
0.0675
benzyl (2-((6-(methylsulfonyl)benzo[d]thiazol-2-yl)amino)-2-oxoethyl)carbamate
pH 7.5, 22°C
0.00319 - 0.00705
benzyl (2E)-3-(3-hydroperoxy-4-hydroxyphenyl)prop-2-enoate
0.00184 - 0.00504
benzyl 4-coumarate
0.0000034 - 0.0076
benzyl sulfamate
0.01 - 0.05
benzylsulfonylsulfamic acid
0.0082 - 85
bicarbonate
0.01 - 0.33
bisulfite
0.0275 - 160
Br-
0.0000009 - 0.11
brinzolamide
0.0097 - 100
bromide
0.000386 - 0.8
but-3-enyl sulfamate
0.000633 - 0.99
but-3-ynyl sulfamate
0.009 - 6.7
Carbonate
0.0099 - 4.003
catechol
94.18
Cd2+
-
in 0.05 M Tris-SO4 buffer, at pH 9.0 and 25°C
0.000016 - 1
celecoxib
7.3 - 7.7
CF3SO3-
0.000003 - 0.000379
chlorazolamide
0.0853 - 100
chloride
0.0000028 - 1.11
Chlorthalidone
0.000001 - 0.000002
chlorzolamide
0.00006134 - 222
Cl-
0.00233
clioquinol
-
at pH 7.5 and 20°C
200
ClO4-
-
above, pH 8.3, 20°C
0.0065 - 51.5
CN-
0.0024 - 11.2
CNO-
0.014 - 1.679
Co2+
0.009 - 9.6
CO32-
0.0001 - 1
coumarin
0.006 - 34.6
CS32-
0.0004 - 48.81
Cu2+
0.00038 - 0.00405
curcumin
0.00025 - 31.7
Cyanate
0.0094 - 51.5
cyanide
0.00006 - 0.059
cyclohexyl sulfamate
0.000027 - 0.000054
dehydroepiandrosterone sulfamate
0.0000265 - 0.684
dichlorophenamide
0.8
diethyldithiocarbamate
-
pH 7.5, 20°C
0.00845 - 0.00937
diflunisal
0.00048 - 0.00192
dobutamin
0.00982
dobutamine
pH 8.3, 22°C
0.0000035 - 0.77
dorzolamide
0.000013 - 0.74
EMD 486019
0.000013 - 0.000032
estradiol 17beta-sulfamate
0.000005 - 0.000058
estradiol 3,17beta-disulfamate
0.00001 - 0.000037
estrone sulfamate
0.004 - 0.96
Et2NCS2-
0.000008 - 0.000034
ethoxazolamide
0.0000008 - 1.113
ethoxzolamide
0.000045 - 0.0505
ethyl 6-(hydroxymethyl)-2-oxo-2H-chromene-3-carboxylate
0.0024 - 0.042
ethyl 7-methoxy-2-oxo-2H-chromene-3-carboxylate
0.001 - 0.038
ethyl sulfamate
0.8 - 0.95
F-
0.703 - 0.915
Fe2+
0.038
fluorenylmethyl sulfamate
-
pH 7.5, 20°C, HCA I
0.0045
fluorenylmethylsulfamate
-
pH 7.5, 20°C, HCA II
0.0544 - 2.85
fluoride
0.69 - 9.5
FSO3-
0.000052 - 0.00139
Furosemide
0.004 - 1.13
H2NSO2NH2
0.005 - 2.45
H2NSO3H
0.096 - 44.9
HCO3-
0.000075 - 0.000193
heptane-1,7-diyl disulfamate
0.543
Hg2+
-
pH 7.4, 25°C, purified enzyme
0.0000003 - 0.0032
homosulfanilamide
0.05 - 20.4
HS-
0.43 - 45.1
HSO3-
0.00029 - 0.00501
hydrochlorothiazide
0.62 - 0.75
hydrogen carbonate
0.00009 - 2
hydrogen sulfide
0.0097 - 11.7
hydrogen sulfite
0.1 - 42
hydrogencarbonate
0.1 - 0.12
Hydroxyurea
0.0085 - 160
I-
0.00000023 - 0.23
indapamide
0.0000034 - 0.00784
indisulam
0.009 - 1.4
Iodide
0.59 - 1.18
isocyanide
0.0004585 - 1.432
Isoorotic acid
0.001 - 0.69
isopropyl sulfamate
0.02 - 0.07
isopropylsulfonylsulfamic acid
0.00000718 - 0.000165
KSCN
0.0038
mafenide
-
pH 8.5, 35°C
0.0000021 - 0.77
methazolamide
0.000109 - 0.369
methyl (3-chloro-4-hydroxyphenyl)acetate
0.000032 - 0.0095
methyl 6-(hydroxymethyl)-2-oxo-2H-chromene-3-carboxylate
0.001 - 0.04
methyl sulfamate
0.02 - 0.1
methylsulfonylsulfamic acid
0.00178
N'',N'''-bis[(E)-(2,6-dichlorophenyl)methylidene]carbonic dihydrazide
pH 7.4, 25°C
0.00358
N'',N'''-bis[(E)-(2-chloro-5-nitrophenyl)methylidene]carbonic dihydrazide
pH 7.4, 25°C
0.00412
N'',N'''-bis[(E)-(2-chlorophenyl)methylidene]carbonic dihydrazide
pH 7.4, 25°C
0.00181
N'',N'''-bis[(E)-(2-nitrophenyl)methylidene]carbonic dihydrazide
pH 7.4, 25°C
0.00252
N'',N'''-bis[(E)-(4-bromophenyl)methylidene]carbonic dihydrazide
pH 7.4, 25°C
0.00235
N'',N'''-bis[(E)-(4-nitrophenyl)methylidene]carbonic dihydrazide
pH 7.4, 25°C
0.000015 - 0.000052
N,N'-biphosphoryl-4,5-dichloro-1,3-benzenesulfonamide
0.03 - 0.07
N,N-dimethylamidimidodisulfuric acid
0.01 - 0.07
N,N-dimethylimidodisulfuric diamide
0.000074 - 1
N-(1-(2-hydroxyphenylamino)-3-methyl-1-oxobutan-2-ylcarbamothioyl)benzamide
0.000068 - 1
N-(1-(2-hydroxyphenylamino)-4-methyl-1-oxopentan-2-ylcarbamothioyl) benzamide
0.000007 - 0.12
N-(2-fluoro-4-sulfamoylphenyl)-2-(thiophen-2-yl)acetamide
0.000008 - 0.000423
N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
0.000413
N-(4-bromophenyl)sulfuric diamide
-
pH 8.3, 20°C
0.000031
N-(4-sulfamoylbenzyl)benzenesulfonamide
-
pH 7.5, 20°C
0.0000062 - 0.08
N-(4-sulfamoylphenyl)-2-(thiophen-2-yl)acetamide
0.0000092 - 0.0000101
N-(4-sulfamoylphenyl)-beta-D-galactopyranosylamine
0.0000089 - 0.0000146
N-(4-sulfamoylphenyl)-beta-D-idopyranosylamine
0.000467
N-(4-sulfamoylphenyl)acetamide
-
pH 7.5, 20°C
0.000095
N-(4-sulfamoylphenyl)benzamide
-
pH 7.5, 20°C
0.000355
N-(4-sulfamoylphenyl)butanamide
-
pH 7.5, 20°C
0.00036
N-(4-sulfamoylphenyl)pentanamide
-
pH 7.5, 20°C
0.000382
N-(4-sulfamoylphenyl)propanamide
-
pH 7.5, 20°C
0.000036
N-(4-[(4-sulfamoylphenyl)sulfamoyl]phenyl)acetamide
-
pH 7.5, 20°C
0.00003 - 0.01
N-(4-[(E)-[(aminosulfonyl)imino]methyl]phenyl)acetamide
0.001 - 0.002
N-(4-[[(aminosulfonyl)amino]sulfonyl]phenyl)acetamide
0.0000105
N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)acetamide
-
at 20°C, pH 8.3
0.0000057 - 0.076
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
0.0000024 - 0.000768
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)furan-2-carboxamide
0.000074 - 0.000125
N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide
0.01 - 0.07
N-(aminosulfonyl)-1,1,1-trichloromethanesulfonamide
0.01 - 0.07
N-(aminosulfonyl)-1,1,1-trifluoromethanesulfonamide
0.002 - 0.04
N-(aminosulfonyl)-1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonamide
0.0011 - 0.03
N-(aminosulfonyl)-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonamide
0.005 - 0.009
N-(aminosulfonyl)-1-(7,7-dimethylbicyclo[2.2.1]hept-1-yl)methanesulfonamide
0.01 - 0.05
N-(aminosulfonyl)-1-phenylmethanesulfonamide
0.00005 - 0.0018
N-(aminosulfonyl)-2,3,4,5,6-pentafluorobenzenesulfonamide
0.001 - 0.0035
N-(aminosulfonyl)-2,4,6-triisopropylbenzenesulfonamide
0.0012 - 0.0039
N-(aminosulfonyl)-2,4,6-tripropylbenzenesulfonamide
0.0009 - 0.0032
N-(aminosulfonyl)-2,5-dichlorobenzenesulfonamide
0.0017 - 0.006
N-(aminosulfonyl)-2-nitrobenzenesulfonamide
0.0008 - 0.0021
N-(aminosulfonyl)-3,5-dichloro-2-hydroxybenzenesulfonamide
0.0009 - 0.0026
N-(aminosulfonyl)-3-(trifluoromethyl)benzenesulfonamide
0.0011 - 0.003
N-(aminosulfonyl)-3-chloro-4-nitrobenzenesulfonamide
0.0016 - 0.005
N-(aminosulfonyl)-3-nitrobenzenesulfonamide
0.01 - 0.04
N-(aminosulfonyl)-4-bromobenzenesulfonamide
0.01 - 0.04
N-(aminosulfonyl)-4-chlorobenzenesulfonamide
0.01 - 0.03
N-(aminosulfonyl)-4-fluorobenzenesulfonamide
0.01 - 0.03
N-(aminosulfonyl)-4-iodobenzenesulfonamide
0.004 - 0.02
N-(aminosulfonyl)-4-methoxybenzenesulfonamide
0.01 - 0.04
N-(aminosulfonyl)-4-methylbenzenesulfonamide
0.0014 - 0.006
N-(aminosulfonyl)-4-nitrobenzenesulfonamide
0.003 - 0.01
N-(aminosulfonyl)-5-(dimethylamino)naphthalene-1-sulfonamide
0.01 - 0.07
N-(aminosulfonyl)benzenesulfonamide
0.02 - 0.09
N-(aminosulfonyl)methanesulfonamide
0.003 - 0.01
N-(aminosulfonyl)naphthalene-1-sulfonamide
0.004 - 0.01
N-(aminosulfonyl)naphthalene-2-sulfonamide
0.02 - 0.1
N-(aminosulfonyl)propane-2-sulfonamide
0.005 - 0.01
N-(aminosulfonyl)quinoline-8-sulfonamide
0.004 - 0.01
N-(aminosulfonyl)thiophene-2-sulfonamide
0.000085 - 0.0114
N-benzyl-2-(3-chloro-4-hydroxyphenyl)acetamide
0.00007 - 0.0031
n-butyl sulfamate
0.000081 - 0.0107
N-butyl-2-(3-chloro-4-hydroxyphenyl)acetamide
0.0000007 - 0.00053
n-decyl sulfamate
0.000009 - 0.00027
n-dodecyl sulfamate
0.000022 - 0.058
n-hexadecyl sulfamate
0.000566 - 0.00405
N-hydroxysulfamide
0.00012 - 0.065
n-octadecyl sulfamate
0.0000027
n-octyl sulfamate
-
pH 7.4, 25°C, hCA II
0.0000035 - 0.000025
n-octylsulfamate
0.000058 - 0.00071
n-pentyl sulfamate
0.0031
N-phenylsulfuric diamide
-
pH 8.3, 20°C
0.000045 - 0.000125
N-phosphoryl-4-carboxy-benzenesulfonamide
0.000002 - 0.000007
N-phosphoryl-6-nitro-benzothiazole-2-sulfonamide
0.000003 - 0.00001
N-phosphoryl-benzothiazole-2-sulfonamide
0.00075 - 0.0037
n-propyl sulfamate
0.00041 - 0.03
N-salicylidene-sulfanilic acid amide
0.000023 - 0.00033
N-salicylidene-sulfanilic acid amide cobalt acetate complex
0.000024 - 0.00033
N-salicylidene-sulfanilic acid amide cobalt chloride complex
0.000025 - 0.00032
N-salicylidene-sulfanilic acid amide cobalt nitrate complex
0.000022 - 0.00035
N-salicylidene-sulfanilic acid amide cobalt sulfate complex
0.000013 - 0.00021
N-salicylidene-sulfanilic acid amide copper chloride complex
0.000015 - 0.00024
N-salicylidene-sulfanilic acid amide copper nitrate complex
0.000037 - 0.00055
N-salicylidene-sulfanilic acid amide nickel acetate complex
0.000039 - 0.00054
N-salicylidene-sulfanilic acid amide nickel chloride complex
0.000039 - 0.00056
N-salicylidene-sulfanilic acid amide nickel nitrate complex
0.000036 - 0.00055
N-salicylidene-sulfanilic acid amide nickel sulfate complex
0.00094 - 0.0658
N-sulfamoyl-beta-D-galactopyranosylamine
0.00197 - 0.0754
N-sulfamoyl-beta-D-glucopyranosylamine
0.00179 - 0.0919
N-sulfamoyl-beta-D-mannopyranosylamine
0.000089 - 0.0114
N-tert-butyl-2-(3-chloro-4-hydroxyphenyl)acetamide
0.000015 - 0.00015
n-tetradecyl sulfamate
0.0000047 - 0.00043
n-undecyl sulfamate
0.00007 - 0.01
N-[(1E)-(1-methyl-1H-pyrrol-2-yl)methylene]sulfamide
0.00002 - 0.01
N-[(1E)-(3,4,5-trimethoxyphenyl)methylene]sulfamide
0.0014 - 0.01
N-[(1E)-(3-nitrophenyl)methylene]sulfamide
0.00004 - 0.01
N-[(1E)-(4-methoxyphenyl)methylene]sulfamide
0.00005 - 0.02
N-[(1E)-(4-methylphenyl)methylene]sulfamide
0.0015 - 0.01
N-[(1E)-(4-nitrophenyl)methylene]sulfamide
0.00004 - 0.01
N-[(1E)-(5-methylthien-2-yl)methylene]sulfamide
0.00006 - 0.02
N-[(1E)-phenylmethylene]sulfamide
0.00005 - 0.01
N-[(1E)-thien-2-ylmethylene]sulfamide
0.00002 - 0.008
N-[(1E)-[4-(dimethylamino)phenyl]methylene]sulfamide
0.0000036 - 0.07455
N-[(2E)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
0.0000036
N-[(2E)-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]furan-2-carboxamide
-
pH 7.5, 20°C
0.001875 - 0.00458
N-[(3aR,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]sulfamic amide
0.004622
N-[(4-[[(4-sulfamoylphenyl)carbamothioyl]amino]phenyl)sulfonyl]acetamide
-
-
0.002519
N-[2,4-disulfamoyl-5-(trifluoromethyl)phenyl]-2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetamide
-
-
0.009034
N-[2,4-disulfamoyl-5-(trifluoromethyl)phenyl]-2-oxo-2H-chromene-3-carboxamide
-
-
0.000031 - 0.0047
N-[4-(aminosulfonyl)phenyl]-2,2,2-trifluoroacetamide
0.000136 - 0.00265
N-[4-(aminosulfonyl)phenyl]-2,2-dimethylpropanamide
0.000138 - 0.0024
N-[4-(aminosulfonyl)phenyl]-2-methylpropanamide
0.000049 - 0.00455
N-[4-(aminosulfonyl)phenyl]acetamide
0.000021 - 0.003245
N-[4-(aminosulfonyl)phenyl]benzamide
0.000083 - 0.00235
N-[4-(aminosulfonyl)phenyl]butanamide
0.000079 - 0.0023
N-[4-(aminosulfonyl)phenyl]pentanamide
0.000056 - 0.0037
N-[4-(aminosulfonyl)phenyl]propanamide
0.01652
N-[4-[(aminooxy)sulfinyl]phenyl]-4-[(diphenylcarbamoyl)amino]benzenesulfonamide
-
-
0.0000021 - 0.1
N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
0.000192
N-[5-[(aminooxy)sulfinyl]-1,3,4-thiadiazol-2-yl]-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonamide
-
-
0.000016 - 0.000058
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-alanine
0.000004 - 0.000029
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-asparagine
0.000011 - 0.000053
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-glutamine
0.000005 - 0.000025
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-isoleucine
0.000007 - 0.000023
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-leucine
0.000005 - 0.000031
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-methionine
0.000008 - 0.000042
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-phenylalanine
0.000048 - 0.000197
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-proline
0.00002 - 0.000064
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-tryptophan
0.000005 - 0.000031
N-[[[4-(aminosulfonyl)phenyl]amino]thioxomethyl]-L-valine
0.0037 - 55.7
N3-
0.0000343 - 0.000668
NaN3
0.002586
naphthalene-2-sulfonamide
-
pH 8.5, 35°C
0.0071 - 0.027
NCO-
6.5 - 7.9
NH(SO3)22-
0.0687 - 36.5
nitrate
0.0612 - 7.3
nitrite
0.0155 - 44.8
NO2-
0.01 - 43.7
NO3-
0.000308 - 0.000723
N~1~-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
0.001858
octane-1-sulfonamide
-
-
0.0007325 - 1.682
Orotic acid
0.0000027 - 0.001
p-methylbenzyl sulfamate
0.000098
p-phenoxyphenylsulfamate
-
pH 7.4, 25°C, hCA II
0.000369
p-trifluoromethylphenylsulfamate
-
pH 7.4, 25°C, hCA I
7.3 - 9.1
P2O74-
0.00923
paracetamol
-
at pH 7.5 and 20°C
0.12 - 0.185
Pb2+
0.000039 - 0.000432
pentachlorophenyl sulfamate
0.000125
pentachlorophenylsulfamate
-
pH 7.4, 25°C, hCA II
0.000047 - 0.000415
pentafluorophenyl sulfamate
5.6 - 7.4
PF6-
0.006 - 32.6
Ph-AsO3H2
0.008 - 22.4
Ph-B(OH)2
0.0055 - 0.0105
phenol
0.87 - 30.84
phenyl arsonic acid
0.81 - 30.85
phenyl boronic acid
0.00256
phenyl sulfamate
-
pH 8.3, 20°C
0.0081
phenyl-boronic acid
-
isozyme STPCA-2, pH not specified in the publication, temperature not specified in the publication
0.000086 - 0.674
phenylacetonitrile
0.000076 - 0.78
phenylarsonic acid
0.000009 - 38.2
phenylboronic acid
0.0000013 - 0.000063
phenylsulfamate
0.01 - 0.06
phenylsulfonylsulfamic acid
0.788
prontosil
20°C, pH 7.5
0.00054 - 0.00741
pyrogallol
0.002 - 0.008
quinolin-8-ylsulfonylsulfamic acid
0.93 - 8.8
ReO4-
0.0077 - 0.795
resorcinol
7.6 - 8.7
RuO4-
4.5 - 9.5
S2O82-
0.0000403 - 12.5
saccharin
0.0071 - 0.74
salicylic acid
0.0285 - 9.3
SCN-
0.88 - 8
SeCN-
6.1 - 8.5
SeO42-
1.8 - 6.7
SnO32-
0.008
SO32-
-
pH 7.5, 20°C, inhibition of CO2 hydration reaction
0.0055 - 63
SO42-
0.00167
sodium (butylsulfonyl)azanide
-
-
0.000122 - 0.00138
sodium (hexylsulfonyl)azanide
0.001789
sodium (octylsulfonyl)azanide
-
-
0.0133 - 0.231
spermine
0.000023 - 0.41
sulfamate
0.000096 - 103
sulfamic acid
0.000048 - 103
sulfamide
0.00000757 - 0.099
sulfanilamide
0.00687 - 0.00872
sulfasalazine
0.0095 - 14.15
sulfate
0.0000008 - 0.0104
sulpiride
0.000006 - 0.63
sulthiame
5.1 - 8.5
TeO42-
0.0066 - 0.0859
tert-butyl (2-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-2-oxoethyl)carbamate
0.0888
tert-butyl (2-((4-methylbenzo[d]thiazol-2-yl)amino)-2-oxoethyl)-carbamate
pH 7.5, 22°C
0.0084 - 0.0782
tert-butyl (2-((6-(methylsulfonyl)benzo[d]thiazol-2-yl)amino)-2-oxoethyl)carbamate
0.0008 - 0.0016
tert-butyl 3-[[(aminosulfonyl)amino]sulfonyl]phenylcarbamate
0.0009 - 0.002
tert-butyl 4-[[(aminosulfonyl)amino]sulfonyl]phenylcarbamate
0.0007 - 0.0024
tert-butyl 5-[[(aminosulfonyl)amino]sulfonyl]-2-hydroperoxyphenylcarbamate
0.0024 - 0.007
thien-2-ylsulfonylsulfamic acid
0.0101 - 55.6
thiocyanate
0.65 - 0.94
Thiocyanide
0.00000038 - 0.78
topiramate
0.000482 - 0.1
umbelliferone
445 - 460
Urea
5.8 - 7.6
V2O74-
0.000013 - 0.154
valdecoxib
2.15 - 7.035
Zn2+
0.0000051 - 2.2
zonisamide
0.000295 - 0.0148
[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-2H,3aH,7H-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate
0.00001 - 0.1
[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate
0.0022 - 0.006
[(7,7-dimethylbicyclo[2.2.1]hept-1-yl)methyl]sulfonylsulfamic acid
0.00006 - 0.0015
[3-(trifluoromethyl)phenyl]sulfonylsulfamic acid
0.00003 - 0.0012
[3-[(tert-butoxycarbonyl)amino]-4-hydroperoxyphenyl]sulfonylsulfamic acid
0.0008 - 0.01
[3-[(tert-butoxycarbonyl)amino]phenyl]sulfonylsulfamic acid
0.00007 - 0.0015
[4-(acetylamino)phenyl]sulfonylsulfamic acid
0.00005 - 0.0012
[4-[(tert-butoxycarbonyl)amino]phenyl]sulfonylsulfamic acid
0.00022 - 0.127
[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]hydrazine
0.002 - 0.008
[5-(dimethylamino)-1-naphthyl]sulfonylsulfamic acid
0.87
[S2O8]2-
-
pH 7.5, 20°C
0.000008 - 0.0003
[[(2-methylphenyl)sulfonyl]amino]carbonylsulfamic acid
0.00005 - 0.0009
[[(2-methylphenyl)sulfonyl]amino]carbonylsulfamic amide
0.000004 - 0.0004
[[(4-chlorophenyl)sulfonyl]amino]carbonylsulfamic acid
0.00005 - 0.0011
[[(4-chlorophenyl)sulfonyl]amino]carbonylsulfamic amide
0.000006 - 0.0003
[[(4-fluorophenyl)sulfonyl]amino]carbonylsulfamic acid
0.00008 - 0.0012
[[(4-fluorophenyl)sulfonyl]amino]carbonylsulfamic amide
0.00001 - 0.0006
[[(4-methylphenyl)sulfonyl]amino]carbonylsulfamic acid
0.00006 - 0.0014
[[(4-methylphenyl)sulfonyl]amino]carbonylsulfamic amide
additional information
additional information
-