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Information on EC 2.7.11.1 - non-specific serine/threonine protein kinase and Organism(s) Homo sapiens and UniProt Accession Q15418

for references in articles please use BRENDA:EC2.7.11.1

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IUBMB Comments

This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analysed to date.

The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
+
a [protein]-(L-serine/L-threonine)
=
+
a [protein]-(L-serine/L-threonine) phosphate

Synonyms
protein kinase a, 14-3-3, camkii, p-akt, lrrk2, c-jun n-terminal kinase, serine/threonine kinase, raf-1, protein kinase b, gsk-3, more

SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ribosomal protein S6 kinase alpha 1
-
3-phosphoinositide dependent protein kinase-1
-
3-phosphoinositide-dependent kinase 1
-
-
5'-AMP-activated protein kinase, catalytic alpha-1 chain
-
5'-AMP-activated protein kinase, catalytic alpha-2 chain
-
90S6K
-
-
A-kinase
-
-
-
-
A-T, mutated
-
-
-
-
A-T, mutated homolog
-
-
-
-
Akt protein kinase
-
AMH type II receptor
-
-
-
-
AMPK
-
-
Anti-sigma B factor rsbT
-
-
-
-
AP50 kinase
-
-
-
-
Ataxia telangiectasia mutated
-
-
-
-
Ataxia telangiectasia mutated homolog
-
-
-
-
ataxia- and Rad3-related
-
Ataxia-telangiectasia and Rad3-Related
-
ataxia-telangiectasia mutated
-
ATP-protein transphosphorylase
-
-
-
-
betaIIPKC
-
-
-
-
Breast-tumor-amplified kinase
-
-
-
-
Calcium-dependent protein kinase C
-
-
-
-
Calcium/phospholipid-dependent protein kinase
-
-
-
-
cAMP-dependent protein kinase A
-
-
-
-
casein kinase
-
-
-
-
casein kinase 1
-
-
casein kinase 1 delta
-
casein kinase 1 gamma1
-
casein kinase 1alpha
-
-
casein kinase 1delta
-
casein kinase 2
casein kinase 2alpha
-
-
casein kinase I
casein kinase I gamma 2
-
casein kinase I, alpha isoform
-
casein kinase I, delta isoform
-
casein kinase I, epsilon isoform
-
casein kinase I, gamma 1 isoform
-
casein kinase I, gamma 2 isoform
-
casein kinase I, gamma 3 isoform
-
casein kinase II
casein kinase-2
casein kinase-II
-
-
CDC25 suppressing protein kinase
-
-
-
-
Cdc7 kinase
Cdc7Hs protein
-
CDK2
-
-
Cell division cycle 2-like
-
-
-
-
cell division cycle 7-related protein kinase
-
checkpoint kinase 1
-
-
CK-2
-
-
-
-
CK-2alpha
-
CK1alpha
-
-
CK1delta
CK1epsilon
-
-
CK1gamma
-
-
CK2-alpha
-
-
-
-
CKI
-
-
-
-
CLP-36 interacting kinase
-
-
-
-
cyclic monophosphate-dependent protein kinase
-
-
-
-
cyclic nucleotide-dependent protein kinase
-
-
-
-
cyclin-dependent kinase
-
-
-
-
cyclin-dependent kinase 2
-
-
cyclin-dependent kinase 5
-
cytidine 3',5'-cyclic monophosphate-responsive protein kinase
-
-
-
-
DAP-kinase
-
-
death-associated protein kinase 1
-
DM kinase
-
DNA-dependent protein kinase catalytic subunit
-
DNA-PKcs
DNPK1
-
-
-
-
dSTPK61
-
-
-
-
G11 protein
-
-
-
-
glycogen synthase kinase 3
glycogen synthase kinase 3 beta
-
-
glycogen synthase kinase 3beta
-
-
glycogen synthase kinase-3
-
-
glycogen synthase kinase-3alphabeta
-
-
glycogen synthase kinase-3beta
-
-
GSK-3beta
-
-
hARK1
-
-
-
-
HIPK2
-
-
histone kinase
-
-
-
-
homeodomain-interacting protein kinase 2
hPDK1
-
-
-
-
Hpr kinase
-
-
-
-
hPSK
-
-
-
-
HSPK 21
-
-
-
-
HSPK 36
-
-
-
-
hydroxyalkyl-protein kinase
-
-
-
-
insulin-stimulated protein kinase
-
Kinase interacting with stathmin
-
-
-
-
kinase, casein (phosphorylating)
-
-
-
-
kinase, protamine (phosphorylating)
-
-
-
-
kinase, protein (phosphorylating)
-
-
-
-
kinase, protein, A (phosphorylating)
-
-
-
-
kinase, protein, C (phosphorylating)
-
-
-
-
leucine-rich repeat kinase 2
-
-
LIM domain kinase 1
-
LKB1
-
-
LRRK2
-
-
Lymphocyte-oriented kinase
-
-
-
-
M phase-specific cdc2 kinase
-
-
-
-
MAP kinase activated protein kinase 2
-
MAP kinase-activated protein kinase 2
-
MAPK-activated protein kinase 2
-
-
MAPKAP kinase-2
-
MAPKAP-K2
-
-
mitogen-activated S6 kinase
-
-
-
-
mitotic checkpoint serine/threonine-protein kinase BUB1
-
mitotic checkpoint serine/threonine-protein kinase BUB1 beta
-
MLK4
-
-
mPDK1
-
-
-
-
MPSK
-
-
-
-
Myristoylated and palmitoylated serine-threonine kinase
-
-
-
-
NDR protein kinase
-
-
nuclear Dbf2-related 1
-
nuclear Dbf2-related protein kinase
-
-
NY-REN-55 antigen
-
-
-
-
p-AKT
-
-
P-CIP2
-
-
-
-
p110alpha
-
p21-activated kinase 4
-
P460
-
-
-
-
p46Eg265
-
-
-
-
p46XlEg22
-
-
-
-
p53-related protein kinase
-
p54 S6 kinase 2
-
p70 S6 kinase
-
p82 kinase
-
-
-
-
pEg2
-
-
-
-
peripheral plasma membrane protein CASK
-
phosphatidylinositol 3-kinase
-
phosphatidylinositol 3-kinase-related kinase
-
phosphoinositide 3-kinase
phosphorylase b kinase kinase
-
-
-
-
Phototropin
-
-
-
-
PI3Kdelta
-
PI3Kgamma
-
Pim-2
-
-
Pim-2h
-
-
-
-
Pim1 serine/threonine kinase
-
PkB kinase
-
-
-
-
PKBalpha
-
-
PKD1
-
-
PKD2
-
-
PKN1
-
-
pp39-mos
-
-
-
-
pp90rsk Ser/Thr kinase
-
Pre-mRNA protein kinase
-
-
-
-
protamine kinase
-
-
-
-
protein casein kinase II
-
-
protein glutamyl kinase
-
-
-
-
protein kinas B
-
-
protein kinase (phosphorylating)
-
-
-
-
protein kinase A
-
-
protein kinase B
-
protein kinase B alpha
-
Protein kinase B kinase
-
-
-
-
protein kinase B/Akt
-
-
protein kinase Balpha
-
-
protein kinase Bgamma
-
protein kinase C
-
-
protein kinase CK2
protein kinase D1
-
-
protein kinase D2
-
-
protein kinase HIPK2
-
Protein kinase Krct
-
-
-
-
Protein kinase MST
-
-
-
-
protein kinase N1
-
-
protein kinase p58
-
-
-
-
Protein kinase PKL12
-
-
-
-
protein kinase PKX1
-
protein kinase Sgk
-
protein phosphokinase
-
-
-
-
protein serine kinase
-
-
-
-
protein serine-threonine kinase
-
-
-
-
protein serine/threonine kinase
-
-
protein-aspartyl kinase
-
-
-
-
protein-cysteine kinase
-
-
-
-
protein-serine kinase
-
-
-
-
protein-serine/threonine kinase
-
-
-
-
PRP4 kinase
-
-
-
-
PRP4 pre-mRNA processing factor 4 homolog
-
-
-
-
PSK-H1
-
-
-
-
RAC-alpha serine/threonine kinase
-
RAC-beta serine/threonine protein kinase
-
RAC-gamma serine/threonine protein kinase
-
RAC/Akt kinase
-
Raf kinase
-
-
-
-
RAF proto-oncogene serine/threonine-protein kinase
-
-
Raf-1
-
-
-
-
ratAurA
-
-
-
-
ribosomal protein S6 kinase
-
ribosomal protein S6 kinase alpha 2
-
ribosomal protein S6 kinase alpha 3
-
ribosomal protein S6 kinase alpha 6
-
ribosomal protein S6 kinase beta 2
-
ribosomal protein S6 kinase II
-
-
-
-
ribosomal S6 kinase (Rsk-2)
-
ribosomal S6 protein kinase
-
-
-
-
RP1 protein
-
-
-
-
S-receptor kinase
-
-
-
-
S6K1alphaII
-
-
serine kinase
-
-
-
-
serine protein kinase
-
-
-
-
serine threonine tyrosine kinase 1
-
-
serine(threonine) protein kinase
-
-
-
-
serine-specific protein kinase
-
-
-
-
serine-threonine kinase
serine-threonine kinase 38
-
serine-threonine protein kinase
-
serine/threonine kinase
serine/threonine kinase 11
-
-
Serine/threonine kinase 15
-
-
-
-
serine/threonine kinase 17A
-
serine/threonine kinase 17B
-
serine/threonine kinase 38
-
Serine/threonine kinase Ayk1
-
-
-
-
serine/threonine kinase PRP4 homolog
-
serine/threonine protein kinase
serine/threonine protein kinase 16
-
serine/threonine protein kinase 31
-
serine/threonine protein kinase R (PKR)-like endoplasmic reticulum kinase
-
serine/threonine-protein kinase
serine/threonine-protein kinase 11
-
serine/threonine-protein kinase Chk1
-
serine/threonine-protein kinase Chk2
-
serine/threonine-protein kinase DCAMKL1
-
serine/threonine-protein kinase H1
-
serine/threonine-protein kinase NEK2
-
serine/threonine-protein kinase NEK3
-
Serine/threonine-protein kinase NRK2
-
-
-
-
Serine/threonine-protein kinase NYD-SPK
-
-
-
-
serine/threonine-protein kinase PAK 1
-
serine/threonine-protein kinase PAK 2
-
serine/threonine-protein kinase PAK 3
-
serine/threonine-protein kinase PAK 4
-
serine/threonine-protein kinase PAK 7
-
serine/threonine-protein kinase Sgk
-
serine/threonine-protein kinase ULK1
-
SGK1
-
-
SPAK/STE20
-
SPS1-related proline alanine-rich kinase
-
SRK
-
-
-
-
Ste20-like kinase
-
-
-
-
STE20-like kinase MST1
-
-
-
-
STE20-like kinase MST2
-
-
-
-
STE20-like kinase MST3
-
-
-
-
Ste20-related protein kinase
-
STE20/SPS1-related proline-alanine rich protein kinase
-
STK11
STYK1
-
-
suppressor of morphogenesis in genitalia-1
-
Switch protein/serine kinase
-
-
-
-
T-antigen kinase
-
-
-
-
tau-protein kinase I
-
-
Tau-tubulin kinase 1
-
-
testis-specific serine/threonine kinase
-
testis-specific serine/threonine kinase 2
-
threonine Pim kinase
-
threonine-specific protein kinase
-
-
-
-
Titin, heart isoform N2-B
-
TPK I
-
-
Twitchin kinase
-
-
-
-
type-2 casein kinase
-
-
-
-
ZIP kinase
-
-
ZIPK
-
-
additional information