EC Number   |
Expression |
Reference |
|---|
   2.7.11.1 | down |
baicalin, one of the major compounds in the Chinese medical herb Scutellaria baicalensis, reduces enzyme expression and activity in badder cancer cells T24 |
722418 |
| 2.7.11.1 | down |
overexpression of microRNA miR-455 decreases protein expression of RAF proto-oncogene serine/threonine-protein kinase (RAF1) but has no effect on mRNA level. miR-455 regulates RAF1 expression directly. Overexpression of miR-455 significantly inhibits the proliferation and the invasion of SW480, but has no effect on apoptosis. Overexpression of RAF1 partially reverses the inhibitory effect of miR-455 on the growth and the invasion of SW480 |
743877 |
| 2.7.11.1 | down |
overexpression of miR-455 decreases protein expression of RAF proto-oncogene serine/threonine-protein kinase RAF1 but has no effect on mRNA level |
739739 |
| 2.7.11.1 | more |
no significant alterations in CPK21 gene expression by drought and salt stress |
-, 723232 |
| 2.7.11.1 | up |
after norepinephrine administration, caseine kinase 2 (CK2), is induced and more active in primary white adipocytes compared to both brown and beige adipocytes. CK2 activity is induced in the inguinal white adipose tissue depot after high-fat feeding. This increase in CK2 activity is selective for white adipose tissue since no change in CK2 activity is found in brown adipose tissue |
742242 |
| 2.7.11.1 | up |
enzyme activity is stimulated by oxidative stresses such as hydrogen peroxide and X-ray irradiation |
738018 |
| 2.7.11.1 | up |
enzyme expression is frequently up-regulated in CRC clinical samples at the protein levels and significantly associated with tumor differentiation grade, lymph node metastasis, TNM stage, and patient death |
737936 |
| 2.7.11.1 | up |
gene knpK is induced by oxidative and nitrosative stress and other stress-associated challenge, overview |
-, 722284 |
| 2.7.11.1 | up |
hypoxia upregulates isoform PDK1. Isoform Pdk1 expression is upregulated by hypoxia inducible factor 1alpha during hypoxic culture of LSK cells in vitro |
762217 |
| 2.7.11.1 | up |
interleukin-6 and TNF family cytokines, TNFalpha, BAFF and APRIL, but not IGF-1 cooperatively enhance the expression of the serine/threonine kinase Pim-2 in multiple myeloma cells. Interleukin-6 and TNF family cytokines cooperatively enhance Pim-2 expression. Cucurbitacin I suppresses the Pim-2 upregulation by interleukin-6. Pim-2 upregulation by TNFalpha is suppressed by parthenolide. STAT3 and NF-kappaB activation mediates Pim-2 upregulation in mutiple myeloma cells |
723080 |
