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Literature summary for 2.7.11.1 extracted from

  • Eiseler, T.; Doeppler, H.; Yan, I.K.; Kitatani, K.; Mizuno, K.; Storz, P.
    Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility via slingshot (2009), Nat. Cell Biol., 11, 545-556.
    View publication on PubMed
Search for more literature for 2.7.11.1

Activating Compound

Activating Compound Comment Organism Structure
H2O2 strong inducer of PKD1 activation Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + SSH1L protein Homo sapiens PKD1 phosphorylates the SSH enzyme SSH1L at serine 978 ADP + SSH1L phosphoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + SSH1L protein PKD1 phosphorylates the SSH enzyme SSH1L at serine 978 Homo sapiens ADP + SSH1L phosphoprotein
-
 ?

Synonyms

Synonyms Comment Organism
PKD1
-
 Homo sapiens
protein kinase D1
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility via slingshot, protein kinase D1 inhibits barbed end formation and directed cell migration Homo sapiens