Literature summary for 2.7.11.1 extracted from

Brown, A.L.; Lee, C.H.; Schwarz, J.K.; Mitiku, N.; Piwnica-Worms, H.; Chung, J.H.
A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage (1999), Proc. Natl. Acad. Sci. USA, 96, 3745-3750.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	activated in response to ionizing radiation	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	kinase functions downstream of ATM protein in the cellular response to DNA damage	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O96017	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	modified by phosphorylation	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	kinase functions downstream of ATM protein in the cellular response to DNA damage	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
HuCds1	-	Homo sapiens
serine/threonine-protein kinase Chk2	-	Homo sapiens

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Release 2023.1 (January 2023)