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Literature summary for 2.7.11.1 extracted from

  • Caples, M.J.; Clements, J.E.; Barber, S.A.
    Protein kinase CK2 phosphorylates the Nef protein from a neurovirulent simian immunodeficiency virus (2006), Virology, 348, 156-164.
    View publication on PubMed
Search for more literature for 2.7.11.1

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + SIV/17E-Fr Nef protein Homo sapiens phosphorylation at Ser12, the protein kinase CK2 associates with the Nef proteins from the Human immunodeficiency virus and the macrophage-tropic neurovirulent Simian immunodeficiency virus clone, SIV/17E-Fr, the Nef protein play important roles in viral disease progression ADP + phosphorylated SIV/17E-Fr Nef protein
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + SIV/17E-Fr Nef protein phosphorylation at Ser12, the protein kinase CK2 associates with the Nef proteins from the Human immunodeficiency virus and the macrophage-tropic neurovirulent Simian immunodeficiency virus clone, SIV/17E-Fr, the Nef protein play important roles in viral disease progression Homo sapiens ADP + phosphorylated SIV/17E-Fr Nef protein
-
 ?
ATP + SIV/17E-Fr Nef protein phosphorylation at Ser12, no or poor activity with SIV/17E-Fr Nef protein mutants S12P and D15A, respectively, in transfected 293T cells, Asp15 of the substrate is important for phosphorylation Homo sapiens ADP + phosphorylated SIV/17E-Fr Nef protein
-
 ?

Synonyms

Synonyms Comment Organism
CK2
-
 Homo sapiens
protein kinase CK2
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens