EC Number   |
Application |
Reference |
|---|
   2.7.11.1 | drug development |
CK2 is a target for drug development and design of selective inhibitors |
671945 |
| 2.7.11.1 | drug development |
protein kinases are major targets for drug development and design in the pharmaceutical industry |
660951 |
| 2.7.11.1 | drug development |
the eukaryotic-like serine/threonine protein kinases are targets for the treatment of tuberculosis |
723741 |
| 2.7.11.1 | drug development |
the kinase activity of protein kinase Balpha has received considerable attention as a drug target, since protein kinase Balpha is constituently active in cancerous cells and requires strict regulation, inhibition of phosphatidylinositol 3,4,5-trisphosphate binding to the PH domain by small molecules has also become a priority target for anticancer treatment |
691787 |
| 2.7.11.1 | medicine |
a phase II trial of enzastaurin is conducted to determine the 6-month progression-free survival rate in advanced non-small-cell lung cancer using Enzaustaurin: 13% of the patients have a progression-free survival for more than 6 months |
693361 |
| 2.7.11.1 | medicine |
enzyme expression is inversely correlated with patient prognosis in mesenchymal, but not proneural high-grade gliomas |
737970 |
| 2.7.11.1 | medicine |
GSK-3 is a target for the therapeutic treatment of Alzheimer's disease and other tauopathies |
662302 |
| 2.7.11.1 | medicine |
GSK3 is an important therapeutic target for gliomas |
691623 |
| 2.7.11.1 | medicine |
high-tidal-volume ventilation induced microvascular permeability, lung fibrosis, and chemokine production are dependent, in part, on activation of the Akt and ERK1/2 pathways |
691922 |
| 2.7.11.1 | medicine |
increased pancreatic islet mass induced by dexamethasone is accompanied by activation of the insulin receptor substrate-2/serine-threonine kinase pathway and augmented cyclin D2 protein levels in insulin-resistant rats |
692669 |
