EC Number   |
Metals/Ions |
Reference |
|---|
   2.7.11.1 | Ca2+ |
3-6fold stimulation |
491415 |
| 2.7.11.1 | Ca2+ |
activity is dependent on |
491360 |
| 2.7.11.1 | Ca2+ |
autophosphorylation activity is repressed upon addition of Ca2+/calmodulin |
491245 |
| 2.7.11.1 | Ca2+ |
can only poorly substitute for Mn2+ |
680441 |
| 2.7.11.1 | Ca2+ |
can partly substitute for Mn2+, activates |
663304 |
| 2.7.11.1 | Ca2+ |
can substitute for Mn2+ in serine/threonine kinase activity |
663129 |
| 2.7.11.1 | Ca2+ |
dependent on |
675373, 738584, 762229 |
| 2.7.11.1 | Ca2+ |
dependent on, the enzymes contain calmodulin-like calcium binding domains, the EF-hands. The plant isozymes display highly variable calcium-dependences for their kinase activities: seven CPKs from subgroups 1 and 2 are clearly sensitive to calcium with different intensities, whereas six CPKs from subgroup 3 exhibit low or no calcium sensitivity to two generic substrates. But all plant isozymes bind calcium, except for CPK25, which is calcium-independent owing to the absence of functional EF-hands. Calcium binding differentially affects CDPK isoforms that may be activated by distinct molecular mechanisms |
721543 |
| 2.7.11.1 | Ca2+ |
dependent on. The CaM-like domain of CPK21 contains, like calmodulin, four single consensus EF-hand motifs forming two pairs of calciumbinding sites |
723232 |
| 2.7.11.1 | Ca2+ |
enzyme contains a neural visinin-like calcium-binding domain |
491381 |
