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Information on EC 2.7.11.1 - non-specific serine/threonine protein kinase and Organism(s) Homo sapiens and UniProt Accession Q15208
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EC Tree 2 Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
IUBMB Comments
This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analysed to date.
The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms
The enzyme appears in selected viruses and cellular organisms
- 2.7.11.1
- jnk
- mapks
-
signal-regulated
- rapamycin
- agonist
- necrosis
- endothelial
- cardiac
- mtor
- parkinsonism
- caspase-3
- metastasis
- bcl-2
- synaptic
- cyclin
- alzheimer
- cyclase
- hippocampal
- forskolin
- sirnas
- neurodegenerative
- autophosphorylation
-
neuroprotective
- creb
-
phorbol
- tumorigenesis
- cardiomyocytes
- wortmannin
- pten
-
cyclin-dependent
- ventricular
- gtpases
- myocytes
- cytoskeleton
-
adenylyl
- nf-kappab
- myocardial
- ischemia
-
dominant-negative
- nmda
-
hyperphosphorylation
-
postsynaptic
-
anti-apoptotic
- src
- phosphoprotein
- isoproterenol
- rhoa
- staurosporine
-
tensin
-
l-type
- medicine
- pharmacology
- molecular biology
- drug development
Reaction Schemes
show+
a [protein]-(L-serine/L-threonine)
=
+
a [protein]-(L-serine/L-threonine) phosphate
Synonyms
protein kinase a, 14-3-3, camkii, p-akt, lrrk2, c-jun n-terminal kinase, serine/threonine kinase, raf-1, protein kinase b, gsk-3, more
topSYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
A-kinase
-
-
-
-
A-T, mutated
-
-
-
-
A-T, mutated homolog
-
-
-
-
AKT
AKT1
AMH type II receptor
-
-
-
-
Anti-sigma B factor rsbT
-
-
-
-
AP50 kinase
-
-
-
-
Ataxia telangiectasia mutated
-
-
-
-
Ataxia telangiectasia mutated homolog
-
-
-
-
ATP-protein transphosphorylase
-
-
-
-
betaIIPKC
-
-
-
-
Breast-tumor-amplified kinase
-
-
-
-
Calcium-dependent protein kinase C
-
-
-
-
Calcium/phospholipid-dependent protein kinase
-
-
-
-
cAMP-dependent protein kinase A
-
-
-
-
casein kinase
-
-
-
-
casein kinase 2
casein kinase I
casein kinase II
casein kinase-2
CDC25 suppressing protein kinase
-
-
-
-
Cdc7 kinase
Cell division cycle 2-like
-
-
-
-
Chk1
CK-2
-
-
-
-
CK1delta
CK2
CK2-alpha
-
-
-
-
CKI
-
-
-
-
CKII
CLP-36 interacting kinase
-
-
-
-
cyclic monophosphate-dependent protein kinase
-
-
-
-
cyclic nucleotide-dependent protein kinase
-
-
-
-
cyclin-dependent kinase
-
-
-
-
cytidine 3',5'-cyclic monophosphate-responsive protein kinase
-
-
-
-
DNA-PKcs
DNPK1
-
-
-
-
dSTPK61
-
-
-
-
G11 protein
-
-
-
-
glycogen synthase kinase 3
GSK3
hARK1
-
-
-
-
histone kinase
-
-
-
-
homeodomain-interacting protein kinase 2
hPDK1
-
-
-
-
Hpr kinase
-
-
-
-
hPSK
-
-
-
-
HSPK 21
-
-
-
-
HSPK 36
-
-
-
-
hydroxyalkyl-protein kinase
-
-
-
-
Kinase interacting with stathmin
-
-
-
-
kinase, casein (phosphorylating)
-
-
-
-
kinase, protamine (phosphorylating)
-
-
-
-
kinase, protein (phosphorylating)
-
-
-
-
kinase, protein, A (phosphorylating)
-
-
-
-
kinase, protein, C (phosphorylating)
-
-
-
-
Lymphocyte-oriented kinase
-
-
-
-
M phase-specific cdc2 kinase
-
-
-
-
mitogen-activated S6 kinase
-
-
-
-
mitotic checkpoint serine/threonine-protein kinase BUB1
-
mitotic checkpoint serine/threonine-protein kinase BUB1 beta
-
mPDK1
-
-
-
-
MPSK
-
-
-
-
myotonin-protein kinase
-
Myristoylated and palmitoylated serine-threonine kinase
-
-
-
-
NY-REN-55 antigen
-
-
-
-
P-CIP2
-
-
-
-
P460
-
-
-
-
p46Eg265
-
-
-
-
p46XlEg22
-
-
-
-
p82 kinase
-
-
-
-
PDK1
pEg2
-
-
-
-
phosphoinositide 3-kinase
phosphorylase b kinase kinase
-
-
-
-
Phototropin
-
-
-
-
PI3K
Pim-2h
-
-
-
-
PIM1
PKA
PKB
PkB kinase
-
-
-
-
pp39-mos
-
-
-
-
Pre-mRNA protein kinase
-
-
-
-
protamine kinase
-
-
-
-
protein glutamyl kinase
-
-
-
-
protein kinase (phosphorylating)
-
-
-
-
Protein kinase B kinase
-
-
-
-
protein kinase CK2
Protein kinase Krct
-
-
-
-
Protein kinase MST
-
-
-
-
protein kinase p58
-
-
-
-
Protein kinase PKL12
-
-
-
-
protein phosphokinase
-
-
-
-
protein serine kinase
-
-
-
-
protein serine-threonine kinase
-
-
-
-
protein-aspartyl kinase
-
-
-
-
protein-cysteine kinase
-
-
-
-
protein-serine kinase
-
-
-
-
protein-serine/threonine kinase
-
-
-
-
PRP4 kinase
-
-
-
-
PRP4 pre-mRNA processing factor 4 homolog
-
-
-
-
PSK-H1
-
-
-
-
RAC-alpha serine/threonine kinase
-
RAC-gamma serine/threonine protein kinase
-
Raf kinase
-
-
-
-
Raf-1
-
-
-
-
ratAurA
-
-
-
-
ribosomal protein S6 kinase II
-
-
-
-
ribosomal S6 protein kinase
-
-
-
-
RP1 protein
-
-
-
-
S-receptor kinase
-
-
-
-
S6K1
serine kinase
-
-
-
-
serine protein kinase
-
-
-
-
serine(threonine) protein kinase
-
-
-
-
serine-specific protein kinase
-
-
-
-
serine-threonine kinase
serine/threonine kinase
Serine/threonine kinase 15
-
-
-
-
Serine/threonine kinase Ayk1
-
-
-
-
serine/threonine protein kinase
serine/threonine protein kinase R (PKR)-like endoplasmic reticulum kinase
-
serine/threonine-protein kinase
Serine/threonine-protein kinase NRK2
-
-
-
-
Serine/threonine-protein kinase NYD-SPK
-
-
-
-
serine/threonine-protein kinase Sgk
-
SRK
-
-
-
-
Ste20-like kinase
-
-
-
-
STE20-like kinase MST1
-
-
-
-
STE20-like kinase MST2
-
-
-
-
STE20-like kinase MST3
-
-
-
-
STK11
Switch protein/serine kinase
-
-
-
-
T-antigen kinase
-
-
-
-
threonine-specific protein kinase
-
-
-
-
Twitchin kinase
-
-
-
-
type-2 casein kinase
-
-
-
-
additional information
casein kinase 2
-
-
-
-
casein kinase 2
-
-
casein kinase I
-
-
-
-
casein kinase II
-
-
-
-
casein kinase-2
-
-
-
-