4.2.1.2: fumarate hydratase

This is an abbreviated version!
For detailed information about fumarate hydratase, go to the full flat file.

Word Map on EC 4.2.1.2

4.2.1.2

succinate

leiomyomatosis

hereditary

tricarboxylic

uterine

leiomyoma

hlrcc

germline

isocitrate

citrate

tca

papillary

krebs

aconitase

carboxylase

citric

predisposition

fibroids

phosphoenolpyruvate

succinyl-coa

nucleoli

l-malic

halo

alpha-ketoglutarate

leiomyosarcoma

oncometabolite

paragangliomas

aspartase

pseudohypoxic

reed

oxalacetate

perinucleolar

hippel-lindau

hysterectomy

chromophobe

1.1.1.37

analysis

2-hydroxyglutarate

synthesis

papules

oncocytomas

medicine

industry

Reaction

(S)-malate

=

fumarate

+

H2O

Synonyms

At2g47510, At5g50950, Bxe_A1038, Bxe_A3136, class II fumarase, Fum, FUM C, FUM1, FUM2, FumA, fumarase, fumarase A, fumarase C, fumarase/mesaconase, fumarate hydratase, FumB, FumC, FumD, FumF, FUMR, hydratase, fumarate, L-malate hydro-lyase, LmFH-1, LmFH-2, LmjF24.0320, LmjF29.1960, mesaconase/fumarase, MmcBC, PF1754, PF1755, rv1098c, scFUMC, slFumC, stFUMC, Tneu_1334, Tneu_1335

ECTree

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.2 fumarate hydratase

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Results	in table
15	Activating Compound
58052	AA Sequence
23	Application
1	CAS Registry Number
35	Cloned(Commentary)
1	Cofactor
12	Crystallization (Commentary)
2255	Disease/ Diagnostics
12	Expression
29	General Information
11	General Stability
1	IC50 Value
84	Inhibitors
86	kcat/KM [mM/s]
6	Ki Value [mM]
159	KM Value [mM]
60	Localization
23	Metals/Ions
61	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
11	Organic Solvent Stability
154	Organism
3	Oxidation Stability
28	Pathway
173	PDB ID
37	pH Optimum
6	pH Range
5	pH Stability
2	pI Value
1	Posttranslational Modification
112	Protein Variants
30	Purification (Commentary)
4	Reaction
3	Reaction Type
134	Reference
57	Source Tissue
27	Specific Activity [micromol/min/mg]
6	Storage Stability
178	Substrates and Products (Substrate)
36	Subunits
115	Synonyms
1	Systematic Name
22	Temperature Optimum [°C]
4	Temperature Range [°C]
28	Temperature Stability [°C]
50	Turnover Number [1/s]

Organism

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Organism on EC 4.2.1.2 - fumarate hydratase

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Arabidopsis thaliana

show

-

Uniprot

Manually annotated by BRENDA team

Azotobacter vinelandii

-

-

-

Manually annotated by BRENDA team

Bacillus subtilis

-

-

-

Manually annotated by BRENDA team

synthrophic propionate-oxidizing bacterium strain MPOB

-

-

Manually annotated by BRENDA team

Campylobacter coli

show

Campylobacter fetus

subsp. fetus ATCC 33246 and subsp. venerealis strain ATCC 19438

-

-

Manually annotated by BRENDA team

Campylobacter jejuni

-

-

-

Manually annotated by BRENDA team

Corynebacterium ammoniagenes

-

-

-

Manually annotated by BRENDA team

Corynebacterium glutamicum

show

Corynebacterium glutamicum DSM 20300

-

SwissProt

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Escherichia coli

show

Escherichia coli FumC

FumC

-

-

Manually annotated by BRENDA team

Escherichia coli K-12

-

SwissProt

Manually annotated by BRENDA team

Escherichia coli K-12 W3110 / K-12

-

SwissProt

Manually annotated by BRENDA team

Escherichia coli O157:H7

-

-

-

Manually annotated by BRENDA team

Escherichia coli O157:H7 ATCC 700728

-

-

-

Manually annotated by BRENDA team

Escherichia coli W3110 / K-12

show

Euglena gracilis

var. bacillaris

-

-

Manually annotated by BRENDA team

Geobacillus stearothermophilus

NU-10

-

-

Manually annotated by BRENDA team

Geobacillus stearothermophilus NU-10

NU-10

-

-

Manually annotated by BRENDA team

Gluconacetobacter diazotrophicus

-

-

-

Manually annotated by BRENDA team

Helianthus annuus

show

Helicobacter pylori

gene HP1325

-

-

Manually annotated by BRENDA team

show

Leishmania major

-

-

-

Manually annotated by BRENDA team

Mesembryanthemum crystallinum

L.

-

-

Manually annotated by BRENDA team

Mesembryanthemum crystallinum L.

L.

-

-

Manually annotated by BRENDA team

Mycobacterium tuberculosis

-

UniProt

Manually annotated by BRENDA team

Mycobacterium tuberculosis ATCC 25618

-

UniProt

Manually annotated by BRENDA team

Paraburkholderia xenovorans

-

UniProt

Manually annotated by BRENDA team

Paraburkholderia xenovorans DSMZ 17367 / LB400

-

UniProt

Manually annotated by BRENDA team

Pelotomaculum thermopropionicum

-

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Pseudomonas aeruginosa

possesses at least two and possibly three fumarases

-

-

Manually annotated by BRENDA team

Pseudomonas fluorescens

-

-

-

Manually annotated by BRENDA team

Pseudomonas fluorescens 13525

-

-

-

Manually annotated by BRENDA team

Pyrobaculum neutrophilum

B1Y931: beta subunit, B1Y932: alpha subunit

UniProt

Manually annotated by BRENDA team

Pyrobaculum neutrophilum DSM 2338

B1Y931: beta subunit, B1Y932: alpha subunit

UniProt

Manually annotated by BRENDA team

Pyrococcus furiosus

Q8U062: alpha-subunit, Q8U063: beta-subunit

Q8U062; Q8U063

UniProt

Manually annotated by BRENDA team

Rattus norvegicus

show

Rhizopus arrhizus

show

Rhizopus arrhizus ATCC 10260

-

UniProt

Manually annotated by BRENDA team

Rickettsia prowazekii

-

UniProt

Manually annotated by BRENDA team

Saccharolobus solfataricus

show

Saccharolobus solfataricus DSM 1616

-

-

-

Manually annotated by BRENDA team

Saccharolobus solfataricus MT-4 / DSM 5833

-

UniProt

Manually annotated by BRENDA team

Saccharomyces bayanus

-

-

-

Manually annotated by BRENDA team

Saccharomyces cerevisiae

show

Saccharomyces sp.

-

-

-

Manually annotated by BRENDA team

Solanum lycopersicum

-

-

-

Manually annotated by BRENDA team

Solanum tuberosum

-

-

-

Manually annotated by BRENDA team

Streptomyces coelicolor

-

-

-

Manually annotated by BRENDA team

Streptomyces lividans

-

-

-

Manually annotated by BRENDA team

Streptomyces thermovulgaris

-

SwissProt

Manually annotated by BRENDA team

show

X-1

-

-

Manually annotated by BRENDA team

Thermus sp. X-1

X-1

-

-

Manually annotated by BRENDA team

Thermus thermophilus

show

uncultured marine microorganism

gene fumF

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

[Brevibacterium] flavum

-

-

-

Manually annotated by BRENDA team

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Release 2023.1 (January 2023)