4.2.1.2: fumarate hydratase
This is an abbreviated version!
For detailed information about fumarate hydratase, go to the full flat file.
Word Map on EC 4.2.1.2
-
4.2.1.2
-
succinate
-
leiomyomatosis
-
hereditary
-
tricarboxylic
-
uterine
-
leiomyoma
-
hlrcc
-
germline
-
isocitrate
-
citrate
-
tca
-
papillary
-
krebs
-
aconitase
-
carboxylase
-
citric
-
predisposition
-
fibroids
-
phosphoenolpyruvate
-
succinyl-coa
-
nucleoli
-
l-malic
-
halo
-
alpha-ketoglutarate
-
leiomyosarcoma
-
oncometabolite
-
paragangliomas
-
aspartase
-
pseudohypoxic
-
reed
-
oxalacetate
-
perinucleolar
-
hippel-lindau
-
hysterectomy
-
chromophobe
-
1.1.1.37
-
analysis
-
2-hydroxyglutarate
-
synthesis
-
papules
-
oncocytomas
-
medicine
-
industry
- 4.2.1.2
- succinate
- leiomyomatosis
- hereditary
-
tricarboxylic
- uterine
- leiomyoma
-
hlrcc
-
germline
- isocitrate
- citrate
- tca
-
papillary
-
krebs
- aconitase
- carboxylase
-
citric
-
predisposition
- fibroids
- phosphoenolpyruvate
- succinyl-coa
- nucleoli
-
l-malic
-
halo
- alpha-ketoglutarate
- leiomyosarcoma
-
oncometabolite
- paragangliomas
- aspartase
-
pseudohypoxic
-
reed
- oxalacetate
-
perinucleolar
-
hippel-lindau
-
hysterectomy
-
chromophobe
-
1.1.1.37
- analysis
- 2-hydroxyglutarate
- synthesis
-
papules
- oncocytomas
- medicine
- industry
Reaction
Synonyms
At2g47510, At5g50950, Bxe_A1038, Bxe_A3136, class II fumarase, Fum, FUM C, FUM1, FUM2, FumA, fumarase, fumarase A, fumarase C, fumarase/mesaconase, fumarate hydratase, FumB, FumC, FumD, FumF, FUMR, hydratase, fumarate, L-malate hydro-lyase, LmFH-1, LmFH-2, LmjF24.0320, LmjF29.1960, mesaconase/fumarase, MmcBC, PF1754, PF1755, rv1098c, scFUMC, slFumC, stFUMC, Tneu_1334, Tneu_1335
ECTree
Advanced search results
Activating Compound
Activating Compound on EC 4.2.1.2 - fumarate hydratase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Cl-
-
activity increases up to 50 mM and remains constant at higher concentrations
-
at 0.1 mM malate and 5 mM phosphate: 14% increase in activity. At 0.1 mM malate and 50 mM phosphate: 60% inhibition. At 1 mM malate and 10 mM phosphate: 80% stimulation
phosphate
-
increases activity at less than 5 mM, competitive inhibition at higher concentrations
-
aerobic purification results in inactive protein, which can only partly be reactivated with Fe2+ and thiol
thiol
storage of the protein for 6 months leads to almost complete loss of its activity, which can be fully restored by the reactivation with Fe2+ and thiol
-
activity of permeabilized cells in hydration of fumaric acid is significantly higher than that of the non-permeabilized ones
-
additional information
-
activity of permeabilized cells in hydration of fumaric acid is significantly higher than that of the non-permeabilized ones
-