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4.2.1.2: fumarate hydratase

This is an abbreviated version!
For detailed information about fumarate hydratase, go to the full flat file.

Word Map on EC 4.2.1.2

Reaction

(S)-malate
=
fumarate
 +
H2O

Synonyms

At2g47510, At5g50950, Bxe_A1038, Bxe_A3136, class II fumarase, Fum, FUM C, FUM1, FUM2, FumA, fumarase, fumarase A, fumarase C, fumarase/mesaconase, fumarate hydratase, FumB, FumC, FumD, FumF, FUMR, hydratase, fumarate, L-malate hydro-lyase, LmFH-1, LmFH-2, LmjF24.0320, LmjF29.1960, mesaconase/fumarase, MmcBC, PF1754, PF1755, rv1098c, scFUMC, slFumC, stFUMC, Tneu_1334, Tneu_1335

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.2 fumarate hydratase

Source Tissue

Source Tissue on EC 4.2.1.2 - fumarate hydratase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
cells from individuals with hereditary leiomyomatosis and renal cell cancer have lower fumarate hydratase enzyme activity than cells from normal controls
Manually annotated by BRENDA team
-
cells from individuals with hereditary leiomyomatosis and renal cell cancer have lower fumarate hydratase enzyme activity than cells from normal controls
Manually annotated by BRENDA team
-
highest fumarase activity detected
Manually annotated by BRENDA team
expression of the mitochondrial (Fum1) and cytosolic (Fum2) isoforms increases during germination of sunflower seeds with the peak of the Fum1 gene on the second day and of the Fum2 gene on the third day
Manually annotated by BRENDA team