Literature summary for 4.2.1.2 extracted from

Phan, I.; Subramanian, S.; Olsen, C.; Edwards, T.E.; Guo, W.; Zhang, Y.; Van Voorhis, W.C.; Stewart, L.J.; Myler, P.J.
Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria (2011), Acta Crystallogr. Sect. F, 67, 1123-1128.

Search for more literature for 4.2.1.2

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli as a His-tagged fusion protein	Rickettsia prowazekii

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystal structure solved at 2.4 A resolution. FumC crystallizes as a homodimer containing two subunits of the normally tetrameric enzyme, in which each chain forms an elongated central four-helix bundle capped by two compact domains at the N- and C-termini	Rickettsia prowazekii

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Rickettsia prowazekii	Q9ZCQ4	-	-

Subunits

Subunits	Comment	Organism
homodimer	crystal structure	Rickettsia prowazekii

Synonyms

Synonyms	Comment	Organism
fumarate hydratase	-	Rickettsia prowazekii

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)