1.1.1.21: aldehyde reductase

This is an abbreviated version, for detailed information about aldehyde reductase, go to the full flat file.

Reaction

alditol
+
NAD(P)+
=
aldose
+
NAD(P)H
+
H+

Synonyms

17betaHSD5, 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, AdhA, AKR1B, AKR1B1, AKR1B10, AKR1B13, AKR1B14, AKR1B3, AKR1C3, AKR4C7, aldehyde reductase, alditol/NADP+ oxidoreductase, alditol: NADP+ 1-oxidoreductase, alditol:NAD(P)+1oxidoreductase, alditol:NADP 1-oxidoreductase, alditol:NADP oxidoreductase, aldo-keto reductase, aldo-keto reductase family 1 member B7, aldoketo reductase 1C3, aldose reductase, aldose reductase 2, aldose reductase-like, aldose reductase-like protein, aldose xylose reductase, ALDRXV4, ALR, ALR1, ALR2, AR, ARI, BAR, Fibroblast growth factor regulated protein, FR-1 protein, GRE3, HAR, HRAR, isobutyraldehyde reductase, More, MVDP, NADPH-aldopentose reductase, NADPH-aldose reductase, polyol dehydrogenase (NADP2), RLAR, small intestine reductase, TPN-polyol dehydrogenase, VAS deferens androgen-dependent protein, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.21 aldehyde reductase

Substrates Products

Substrates Products on EC 1.1.1.21 - aldehyde reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(1S)-camphorquinone + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
(3R,4S/3S,4R)-3,4-(cis)acetate-beta-lactam + NADPH + H+
4-hydroxyazetidine-2,3-diyl diacetate + NADP+
show the reaction diagram
-
screening of 19 individual yeast reductases for their effciency and enantioselectivity, overview
stereochemistry of products of the different enzymes, detailed overview
-
?
(S)-1-indanol + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
(S)-1-teralol + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
1-butanal + NADPH + H+
1-butanol + NADP+
show the reaction diagram
-
-
-
-
?
1-butanal + NADPH + H+
butanol + NADP+
show the reaction diagram
-
-
-
?
1-decanal + NADPH + H+
1-decanol + NADP+
show the reaction diagram
-
-
-
-
?
1-decanol + NADP+
decanal + NADPH + H+
show the reaction diagram
-
-
-
?
1-dodecanal + NADPH + H+
dodecanol + NADP+
show the reaction diagram
-
-
-
?
1-heptanal + NADPH + H+
heptanol + NADP+
show the reaction diagram
-
-
-
?
1-hexanal + NADPH + H+
1-hexanol + NADP+
show the reaction diagram
-
-
-
-
?
1-hexanal + NADPH + H+
hexanol + NADP+
show the reaction diagram
-
-
-
?
1-hydroxynonen-4-one + NADPH
1,4-dihydroxynon-2-ene + NADP+
show the reaction diagram
-
-
-
-
?
1-nonanal + NADPH + H+
1-nonanol + NADP+
show the reaction diagram
-
-
-
-
?
1-nonanal + NADPH + H+
nonanol + NADP+
show the reaction diagram
-
-
-
?
1-nonanol + NADP+
nonanal + NADPH + H+
show the reaction diagram
-
-
-
?
1-palmitoyl-2-(5-oxovaleryl)sn-glycero-3-phosphocholine + NADPH
1-palmitoyl-2-(5-hydroxyvaleryl)sn-glycero-3-phosphocholine + NADP+
show the reaction diagram
-
-
-
-
?
1-palmitoyl-2-(5-oxovaleryl)sn-glycero-3-phosphocholine + NADPH + H+
? + NADP+
show the reaction diagram
ALR2
-
-
?
1-propanal + NADPH + H+
1-propanol + NADP+
show the reaction diagram
-
-
-
-
?
1-tetradecanol + NADP+
tetradecanal + NADPH + H+
show the reaction diagram
-
-
-
?
11-deoxyisocorticosterone + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
16-ketoestrone + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2,3-bornanedione + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
2,3-butanedione + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2,3-heptanedione + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2,3-hexanedione + NADPH + H+
?
show the reaction diagram
2,3-pentanedione + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2,4-decadienal + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2,4-nonadienal + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2-D-deoxy-2-fluoro-galactose + NADPH
?
show the reaction diagram
-
-
-
-
r
2-D-deoxygalactose + NADPH
?
show the reaction diagram
2-decenal + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2-deoxyribose + NADPH
?
show the reaction diagram
-
-
-
-
r
2-hexenal + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2-nonenal + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
2-phenyl-2-propenal + NADPH + H+
2-phenyl-1-propanol + NADP+
show the reaction diagram
-
-
-
-
?
20-isocortisol + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
20alpha-hydroxyprogesterone + NADPH + H+
?
show the reaction diagram
-
-
-
?
20alpha-isocorticosterone + NAD(P)H
?
show the reaction diagram
21-dehydrocortisol + NADPH + H+
?
show the reaction diagram
3,4-hexanedione + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
3-deoxyglucosone + NADPH + H+
?
show the reaction diagram
3-glutathionyl-4-hydroxynonanal + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
4-hydroxy-trans-2-nonenal + NADPH + H+
1,4-dihydroxynonane + NADP+
show the reaction diagram
-
-
-
-
?
4-hydroxynonenal + NADPH + H+
4-hydroxynonanol + NADP+
show the reaction diagram
4-hydroxynonenal + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
4-hydroxyphenylacetaldehyde + NAD(P)H
4-hydroxyphenylethyl alcohol + NAD(P)+
show the reaction diagram
-
-
-
-
?
4-hydroxyphenylglycolaldehyde + NAD(P)H
?
show the reaction diagram
-
-
-
-
?
4-nitrobenzaldehyde + NAD(P)H
4-nitrobenzyl alcohol + NAD(P)+
show the reaction diagram
4-nitrobenzaldehyde + NADPH + H+
4-nitrobenzyl alcohol + NADP+
show the reaction diagram
4-nitrobenzaldehyde + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
4-oxonon-2-enal + NADPH
1-hydroxynonen-4-one + NADP+
show the reaction diagram
-
-
-
-
?
5-pregnene-3beta,20alpha-diol + NADPH
?
show the reaction diagram
-
-
-
?
5alpha-pregnan-20alpha-ol-3-one + NADPH + H+
?
show the reaction diagram
-
-
-
?
5alpha-pregnane-3beta,20alpha-diol + NADPH + H+
?
show the reaction diagram
-
-
-
?
8-acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one + NADPH + H+
? + NADP+
show the reaction diagram
fluorogenic synthetic substrate
-
-
?
acetaldehyde + NAD(P)H + H+
ethanol + NAD(P)+
show the reaction diagram
acetaldehyde + NADPH + H+
ethanol + NADP+
show the reaction diagram
acetol + NADPH
propane-1,2 diol + NADP+
show the reaction diagram
-
-
-
-
?
acrolein + NADPH
2-propen-1-ol + NADP+
show the reaction diagram
-
-
-
-
?
acrolein + NADPH + H+
2-propen-1-ol + NADP+
show the reaction diagram
-
-
-
-
?
alditol + NAD(P)+
aldose + NAD(P)H
show the reaction diagram
aldose + NAD(P)H
alditol + NAD(P)+
show the reaction diagram
aldose + NADPH + H+
alditol + NADP+
show the reaction diagram
benzaldehyde + NAD(P)H
benzyl alcohol + NAD(P)+
show the reaction diagram
benzaldehyde + NADPH + H+
benzyl alcohol + NADP+
show the reaction diagram
benzyl alcohol + oxidized 3-acetylpyridine adenine dinucleotide + H+
benzaldehyde + reduced 3-acetylpyridine adenine dinucleotide
show the reaction diagram
butyraldehyde + NAD(P)H
butanol + NAD(P)+
show the reaction diagram
D-arabinose + NADPH
arabitol + NADP+
show the reaction diagram
-
-
-
-
r
D-arabinose + NADPH + H+
arabitol + NADP+
show the reaction diagram
-
-
-
-
?
D-erythrose + NAD(P)H
erythritol + NAD(P)+
show the reaction diagram
D-erythrose + NADPH + H+
?
show the reaction diagram
D-fructose + NAD(P)H + H+
D-arabino-hexitol + NAD(P)+
show the reaction diagram
D-fucose + NADPH
fucitol + NADP+
show the reaction diagram
-
-
-
-
r
D-galactose + NAD(P)H
dulcitol + NAD(P)+
show the reaction diagram
D-galactose + NADPH
?
show the reaction diagram
D-galactose + NADPH + H+
?
show the reaction diagram
D-galactose + NADPH + H+
D-galactitol + NADP+
show the reaction diagram
D-glucose + NAD(P)H
sorbitol + NAD(P)+
show the reaction diagram
D-glucose + NADPH + H+
D-sorbitol + NADP+
show the reaction diagram
D-glucose + NADPH + H+
sorbitol + NADP+
show the reaction diagram
D-glucuronate + NAD(P)H
?
show the reaction diagram
D-glucuronate + NADPH
?
show the reaction diagram
-
-
-
-
?
D-glucuronate + NADPH
? + NADP+
show the reaction diagram
D-glucuronolactone + NADPH
?
show the reaction diagram
D-glyceraldehyde + NAD(P)H
glycerol + NAD(P)+
show the reaction diagram
D-glyceraldehyde + NADPH + H+
glycerol + NADP+
show the reaction diagram
D-lactaldehyde + NADPH + H+
?
show the reaction diagram
-
-
-
?
D-lactoaldehyde + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
D-lyxose + NADPH
arabitol + NADP+
show the reaction diagram
D-mannose NAD(P)H
mannitol + NAD(P)+
show the reaction diagram
D-ribose + NAD(P)H
ribitol + NAD(P)+
show the reaction diagram
D-ribose + NADPH
adonitol + NADP+
show the reaction diagram
-
-
-
-
r
D-ribose + NADPH + H+
?
show the reaction diagram
D-ribose + NADPH + H+
D-ribitol + NADP+
show the reaction diagram
-
-
-
-
?
D-ribose 5-phosphate + NADPH
D-ribitol 5-phosphate + NADP+
show the reaction diagram
-
-
-
-
r
D-tagatose + NADPH
?
show the reaction diagram
-
-
-
-
r
D-xylose + NAD(P)H
xylitol + NAD(P)+
show the reaction diagram
D-xylose + NADPH
?
show the reaction diagram
-
-
-
-
?
D-xylose + NADPH
xylitol + NADP+
show the reaction diagram
D-xylose + NADPH + H+
?
show the reaction diagram
D-xylose + NADPH + H+
D-xylitol + NADP+
show the reaction diagram
-
-
-
-
?
D-xylose + NADPH + H+
xylitol + NADP+
show the reaction diagram
-
-
-
-
?
D-xylose 5-phosphate + NADPH
D-xylitol 5-phosphate + NADP+
show the reaction diagram
-
-
-
-
r
D-xylulose + NADPH + H+
D-xylitol + NADP+
show the reaction diagram
-
-
-
-
?
decanal + NAD(P)H
decanol + NAD(P)+
show the reaction diagram
-
-
-
-
?
dihydroxyacetone + NAD(P)H
glycerol + NAD(P)+
show the reaction diagram
-
-
-
-
?
DL-glyceraldehyde + NAD(P)H
glycerol + NAD(P)+
show the reaction diagram
DL-glyceraldehyde + NADPH
glycerol + NAD(P)+
show the reaction diagram
-
-
-
-
?
DL-glyceraldehyde + NADPH
glycerol + NADP+
show the reaction diagram
DL-glyceraldehyde + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
DL-glyceraldehyde + NADPH + H+
DL-glycerol + NADP+
show the reaction diagram
DL-glyceraldehyde + NADPH + H+
glycerol + NADP+
show the reaction diagram
DL-glyceraldehyde + NADPH + H+
glyycerol + NADP+
show the reaction diagram
-
-
-
-
?
farnesal + NADPH + H+
trans,trans-farnesol + NADP+
show the reaction diagram
specific substrate
-
-
?
geraniol + NADP+
geranial + NADPH + H+
show the reaction diagram
-
-
-
?
geranylgeranial + NADPH + H+
geranylgeraniol + NADP+
show the reaction diagram
specific substrate
-
-
?
glucose + NADPH
sorbitol + NADP+
show the reaction diagram
glutathione-4-hydroxy-trans-2-nonenal + NADPH + H+
glutathione-1,4-dihydroxynonane + NADP+
show the reaction diagram
-
-
-
-
?
glutathione-S-4-oxonon-2-enal + NADPH
S-(1-hydroxy-4-oxonona-3-yl)glutathione + NADP+
show the reaction diagram
-
-
-
-
?
glyceraldehyde + NADPH + H+
glycerol + NADP+
show the reaction diagram
glycoaldehyde + NADPH
ethylene glycol + NADP+
show the reaction diagram
-
-
-
-
?
glycoaldehyde + NADPH + H+
ethylene glycol + NADP+
show the reaction diagram
-
-
-
-
?
glycolaldehyde + NADPH + H+
?
show the reaction diagram
-
-
-
?
glyoxal + NADPH
?
show the reaction diagram
-
-
-
-
?
glyoxal + NADPH + H+
?
show the reaction diagram
hexanal + NADPH + H+
hexanol + NADP+
show the reaction diagram
indole-3-acetaldehyde + NAD(P)H
indole-3-ethanol + NAD(P)+
show the reaction diagram
-
-
-
-
?
isatin + NADPH + H+
3-hydroxyisatin + NADP+
show the reaction diagram
specific substrate
-
-
?
isatin + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
isobutyraldehyde + NADPH + H+
isobutanol + NADP+
show the reaction diagram
isocaproaldehyde + NADPH + H+
?
show the reaction diagram
-
-
-
?
L-arabinose + NAD(P)H
L-arabitol + NAD(P)+
show the reaction diagram
L-arabinose + NADPH
arabitol + NADP+
show the reaction diagram
-
-
-
-
r
L-fucose + NADPH
fucitol + NADP+
show the reaction diagram
-
-
-
-
r
L-glyceraldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
L-idose + NADPH + H+
alditol + NADP+
show the reaction diagram
L-lyxose + NADPH
arabitol + NADP+
show the reaction diagram
-
-
-
-
r
L-rhamnose + NADPH
L-rhamnitol + NADP+
show the reaction diagram
-
-
-
-
r
L-ribose + NADPH
adonitol + NADP+
show the reaction diagram
-
-
-
-
r
L-sorbose + NADPH
L-sorbitol + NADP+
show the reaction diagram
-
-
-
-
r
L-threose + NADPH + H+
?
show the reaction diagram
L-xylose + NAD(P)H
L-xylitol + NAD(P)+
show the reaction diagram
malondialdehyde + NADPH + H+
?
show the reaction diagram
-
-
-
?
methylglyoxal + NADPH
?
show the reaction diagram
methylglyoxal + NADPH + H+
?
show the reaction diagram
methylglyoxal + NADPH + H+
acetol + NADP+
show the reaction diagram
-
-
-
-
?
n-pentanal + NAD(P)H + H+
n-pentanol + NAD(P)+
show the reaction diagram
nerol + NADPH + H+
?
show the reaction diagram
-
-
-
?
octanal + NADPH + H+
1-octanol + NADP+
show the reaction diagram
-
-
-
-
?
octanal + NADPH + H+
octanol + NADP+
show the reaction diagram
-
-
-
?
pentose + NADPH
pentitol + NADP+
show the reaction diagram
pentose + NADPH + H+
pentiol + NADP+
show the reaction diagram
phenyl-1,2-propanedione + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
phenylglyoxal + NAD(P)H
?
show the reaction diagram
phenylglyoxal + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
propanal + NADPH + H+
n-propanol + NADP+
show the reaction diagram
-
-
-
-
r
propionaldehyde + NAD(P)H
propanol + NAD(P)+
show the reaction diagram
pyridine-3-aldehyde + NAD(P)H
3-hydroxypyridine + NAD(P)+
show the reaction diagram
pyridine-3-aldehyde + NADPH + H+
3-hydroxypyridine + NADP+
show the reaction diagram
pyridine-3-methanol + NADP+
?
show the reaction diagram
-
-
-
?
pyridine-3-methanol + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
pyridine-4-aldehyde + NAD(P)H
4-hydroxypyridine + NAD(P)+
show the reaction diagram
-
-
-
-
r
pyridine-4-aldehyde + NADPH + H+
4-hydroxypyridine + NADP+
show the reaction diagram
-
-
-
-
?
pyridinecarboxaldehyde + NAD(P)H
pyridylmethanol + NAD(P)+
show the reaction diagram
sorbitol + NAD+
D-fructose + NADH + H+
show the reaction diagram
succinic semialdehyde + NADH + H+
4-hydroxybutyrate + NAD+
show the reaction diagram
trans-2-buten-1-al + NADPH + H+
?
show the reaction diagram
-
-
-
?
trans-2-decen-1-al + NADPH + H+
?
show the reaction diagram
-
-
-
?
trans-2-hexen-1-al + NADPH + H+
?
show the reaction diagram
-
-
-
?
trans-2-nonen-1-al + NADPH + H+
?
show the reaction diagram
-
-
-
?
xylitol + NAD(P)+
D-xylose + NAD(P)H + H+
show the reaction diagram
additional information
?
-