Application | Comment | Organism |
---|---|---|
medicine | ALR2 is a critical target to prevent and control diabetic complications through the inhibition of its activity | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
aldose + NADPH + H+ | Homo sapiens | - |
alditol + NADP+ | - |
? | |
D-glucose + NADPH + H+ | Homo sapiens | - |
sorbitol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
aldose + NADPH + H+ | - |
Homo sapiens | alditol + NADP+ | - |
? | |
D-glucose + NADPH + H+ | - |
Homo sapiens | sorbitol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aldose reductase | - |
Homo sapiens |
ALR2 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | dependent on | Homo sapiens |