1.1.1.21: aldehyde reductase

This is an abbreviated version, for detailed information about aldehyde reductase, go to the full flat file.

Reaction

alditol
+
NAD(P)+
=
aldose
+
NAD(P)H
+
H+

Synonyms

17betaHSD5, 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, AdhA, AKR1B, AKR1B1, AKR1B10, AKR1B13, AKR1B14, AKR1B3, AKR1C3, AKR4C7, aldehyde reductase, alditol/NADP+ oxidoreductase, alditol: NADP+ 1-oxidoreductase, alditol:NAD(P)+1oxidoreductase, alditol:NADP 1-oxidoreductase, alditol:NADP oxidoreductase, aldo-keto reductase, aldo-keto reductase family 1 member B7, aldoketo reductase 1C3, aldose reductase, aldose reductase 2, aldose reductase-like, aldose reductase-like protein, aldose xylose reductase, ALDRXV4, ALR, ALR1, ALR2, AR, ARI, BAR, Fibroblast growth factor regulated protein, FR-1 protein, GRE3, HAR, HRAR, isobutyraldehyde reductase, More, MVDP, NADPH-aldopentose reductase, NADPH-aldose reductase, polyol dehydrogenase (NADP2), RLAR, small intestine reductase, TPN-polyol dehydrogenase, VAS deferens androgen-dependent protein, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.21 aldehyde reductase

Molecular Weight

Molecular Weight on EC 1.1.1.21 - aldehyde reductase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
29000
-
isozyme AR I, gel filtration
30000
-
isozyme AR II, gel filtration
30500
-
2 * 30500, SDS-PAGE
31000
-
gel filtration
31700
-
subunit, calculated from amino acid sequence
32500
-
1 * 32500, SDS-PAGE in presence of urea and 2-mercaptoethanol
34300
-
gel filtration
34560
-
calculated from amino acid sequence; recombinant enzyme, MALDI-TOF mass spectrometry
34561
-
1 * 34561, MALDI-TOF mass spectrometry
35100
-
1 * 35100, SDS-PAGE in presence of 2-mercaptoethanol
35700
-
x * 35700, electrospray ionisation mass spectrometry data
35727
-
x * 35727, sequence calculation
35800
-
-
35960
-
x * 35960, electrospray ionisation mass spectrometry data
37000
-
gel filtration
39000
-
sucrose density gradient centrifugation, thin layer gel filtration
40200
-
1 * 40200, aldose reductase 1, SDS-PAGE
41500
-
1 * 41500, aldose reductase 2, SDS-PAGE
43000
-
gel filtration
58000
-
ALR1 und ALR 2, theoretical molar mass 76000 Da
61000
-
gel filtration
67000
-
gel filtration
69700
-
equilibrium ultracentrifugation
74000
-
recombinant enzyme with a maltose binding tag, SDS-PAGE