1.1.1.21: aldehyde reductase

This is an abbreviated version, for detailed information about aldehyde reductase, go to the full flat file.

Reaction

alditol
+
NAD(P)+
=
aldose
+
NAD(P)H
+
H+

Synonyms

17betaHSD5, 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, AdhA, AKR1B, AKR1B1, AKR1B10, AKR1B13, AKR1B14, AKR1B3, AKR1C3, AKR4C7, aldehyde reductase, alditol/NADP+ oxidoreductase, alditol: NADP+ 1-oxidoreductase, alditol:NAD(P)+1oxidoreductase, alditol:NADP 1-oxidoreductase, alditol:NADP oxidoreductase, aldo-keto reductase, aldo-keto reductase family 1 member B7, aldoketo reductase 1C3, aldose reductase, aldose reductase 2, aldose reductase-like, aldose reductase-like protein, aldose xylose reductase, ALDRXV4, ALR, ALR1, ALR2, AR, ARI, BAR, Fibroblast growth factor regulated protein, FR-1 protein, GRE3, HAR, HRAR, isobutyraldehyde reductase, More, MVDP, NADPH-aldopentose reductase, NADPH-aldose reductase, polyol dehydrogenase (NADP2), RLAR, small intestine reductase, TPN-polyol dehydrogenase, VAS deferens androgen-dependent protein, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.21 aldehyde reductase

pH Optimum

pH Optimum on EC 1.1.1.21 - aldehyde reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5.8 - 6.7
-
-
6
-
reduction of D-xylose, NADH
6 - 7
-
aldehyde reduction
7 - 8
-
assay at
7.5
-
assay at
8
-
phosphate buffer, Tris-HCl buffer, substrate: DL-glyceraldehyde 3-pyridine carboxaldehyde
8.6 - 9
-
glycine-NaOH buffer, substrate: DL-glyceraldehyde 3-pyridine carboxaldehyde
8.9
-
oxidation of xylitol, NAD+
9 - 10
-
using 0.1 mM geraniol as substrate
9.7 - 10.4
-
glycerol + NAD(P)H
10
-
glycerol + NADP+
additional information
-
pH preference depends on the substrate