EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.205 | IMP dehydrogenase |
prostate gland cancer cell |
- |
761611 |
1.1.1.64 | testosterone 17beta-dehydrogenase (NADP+) |
prostate gland cancer cell |
the enzyme (17beta-HSD3) is over-expressed in hormone-dependent prostate cancer |
762479 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
prostate gland cancer cell |
- |
744413 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
prostate gland cancer cell |
- |
756531 |
1.3.1.124 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] |
prostate gland cancer cell |
castration-resistant prostate cancer |
759825 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland cancer cell |
- |
763398 |
1.5.8.3 | sarcosine dehydrogenase |
prostate gland cancer cell |
- |
725421 |
2.1.1.20 | glycine N-methyltransferase |
prostate gland cancer cell |
LNCaP cells and PC-3 cells |
720403 |
2.1.1.357 | [histone H3]-lysine36 N-dimethyltransferase |
prostate gland cancer cell |
- |
753720 |
2.3.1.13 | glycine N-acyltransferase |
prostate gland cancer cell |
- |
758269 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
prostate gland cancer cell |
- |
759018 |
2.7.1.105 | 6-phosphofructo-2-kinase |
prostate gland cancer cell |
- |
761915 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
prostate gland cancer cell |
- |
760540 |
2.7.1.32 | choline kinase |
prostate gland cancer cell |
- |
760183 |
2.7.11.21 | polo kinase |
prostate gland cancer cell |
- |
760980 |
2.8.2.2 | alcohol sulfotransferase |
prostate gland cancer cell |
- |
761662, 761881 |
3.1.3.43 | [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase |
prostate gland cancer cell |
pyruvate dehydrogenase subunit PDHA1 and pyruvate dehydrogenase phosphatase PDP1 are frequently amplified and overexpressed at both the gene and protein levels in prostate tumors |
751678 |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
prostate gland cancer cell |
compared to normal prostate cells or stroma, in malignant epithelium, expression of ARSB and Dickkopf Wnt Signaling Pathway Inhibitor DKK3 declines, and expression of galactose-6-sulfate-sulfatase and Wnt signaling targets increases |
752087 |
3.1.6.2 | steryl-sulfatase |
prostate gland cancer cell |
- |
716213 |
3.4.17.21 | Glutamate carboxypeptidase II |
prostate gland cancer cell |
considerably increased in prostate carcinoma |
753584 |
3.4.17.21 | Glutamate carboxypeptidase II |
prostate gland cancer cell |
lymph node metastasis, PSMA is highly expressed in 100% of the lymph node metastases originating from prostate cancer |
710456 |
3.4.17.21 | Glutamate carboxypeptidase II |
prostate gland cancer cell |
prostatic adenocarcinoma and intraepithelial neoplasia |
668866 |
3.4.21.122 | transmembrane protease serine 2 |
prostate gland cancer cell |
higher levels of TMPRSS2 expression correlate with higher levels of matriptase activation in prostate cancer tissues |
753143 |
3.4.21.122 | transmembrane protease serine 2 |
prostate gland cancer cell |
primary prostate cancer and prostate cancer metastases. TMPRSS2 expression is significantly higher in both neoplastic prostate and in the epithelium of prostatic hyperplasia compared to normal epithelium. TMPRSS2 expression is further elevated in higher Gleason grade cancers (patterns 4 and 5) compared to pattern 3 |
753135 |
3.4.21.122 | transmembrane protease serine 2 |
prostate gland cancer cell |
TMPRSS2 protease is highly expressed in metastatic prostate cancers |
753135 |
3.4.21.35 | tissue kallikrein |
prostate gland cancer cell |
- |
753294 |
3.4.21.77 | semenogelase |
prostate gland cancer cell |
- |
717088 |
3.4.22.15 | cathepsin L |
prostate gland cancer cell |
- |
752950, 755110 |
3.4.22.26 | cancer procoagulant |
prostate gland cancer cell |
prostate tumor |
697471 |
3.4.22.34 | Legumain |
prostate gland cancer cell |
legumain is overexpressed in the majority of human solid tumours, including breast cancer, colorectal cancer, ovarian cancer, prostate cancer and gastric cancer |
752851 |
3.4.22.49 | separase |
prostate gland cancer cell |
overexpressed in numerous human cancers including breast, bone, brain, and prostate |
752903 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
prostate gland cancer cell |
- |
720437 |
3.4.24.B7 | matrix metalloproteinase-26 |
prostate gland cancer cell |
androgen-repressed prostate cancer cell |
754226 |
3.5.1.60 | N-(long-chain-acyl)ethanolamine deacylase |
prostate gland cancer cell |
the total levels of NAAA mRNAs in androgen-sensitive cells like LNCaP are higher than those in androgen-insensitive cells |
752811 |
5.1.3.17 | heparosan-N-sulfate-glucuronate 5-epimerase |
prostate gland cancer cell |
- |
749412 |