Reference on EC 4.1.1.17 - ornithine decarboxylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Katz, A.; Kahana, C.
Isolation and characterization of the mouse ornithine decarboxylase gene
J. Biol. Chem.
263
7604-7609
1988
Mus musculus
Phillips, M.A.; Coffino, P.; Wang, C.C.
Trypanosoma brucei ornithine decarboxylase: enzyme purification, characterization, and expression in Escherichia coli
J. Biol. Chem.
263
17933-17941
1988
Trypanosoma brucei
Pandit, M.; Ghosh, B.
Ornithine decarboxylase from embryos of jute seeds
Phytochemistry
27
1609-1610
1988
Corchorus olitorius
-
Koromilas, A.E.; Kyriakidis, D.A.
Purification and properties of ornithine decarboxylase from germinated barley seeds
Phytochemistry
27
989-992
1988
Hordeum vulgare
-
Kitani, T.; Fujisawa, H.
Molecular properties of ornithine decarboxylase from mouse kidney. Detailed comparison with those of the enzyme from rat liver
J. Biochem.
103
547-553
1988
Mus musculus, Rattus norvegicus
Phillips, M.A.; Coffino, P.; Wang, C.C.
Cloning and sequencing of the ornithine decarboxylase gene from Trypanosoma brucei. Implications for enzyme turnover and selective difluoromethylornithine inhibition
J. Biol. Chem.
262
8721-8727
1987
Trypanosoma brucei
DiGangi, J.J.; Seyfzadeh, M.; Davis, R.H.
Ornithine decarboxylase from Neurospora crassa. Purification, characterization, and regulation by inactivation
J. Biol. Chem.
262
7889-7893
1987
Neurospora crassa
O'Brien, T.G.; Madara, T.; Pyle, J.A.; Holmes, M.
Ornithine decarboxylase from mouse epidermis and epidermal papillomas: differences in enzymatic properties and structure
Proc. Natl. Acad. Sci. USA
83
9448-9452
1986
Mus musculus
Laitinen, P.H.; Hietala, O.A.; Pulkka, A.E.; Pajunen, A.E.I.
Purification of mouse brain ornithine decarboxylase reveals its presence as an inactive complex with antizyme
Biochem. J.
236
613-616
1986
Mus musculus
Sklaviadis, T.K.; Georgatsos, J.G.; Kyriakidis, D.A.
Purification and properties of ornithine decarboxylase from Tetrahymena pyriformis
Biochim. Biophys. Acta
831
288-296
1985
Tetrahymena pyriformis
Seely, J.E.; Persson, L.; Sertich, G.J.; Pegg, A.E.
Comparison of ornithine decarboxylase from rat liver, rat hepatoma and mouse kidney
Biochem. J.
226
577-586
1985
Mus musculus, Rattus norvegicus
Flamigni, F.; Guarnieri, C.; Caldarera, C.M.
Characterization of highly purified ornithine decarboxylase from rat heart
Biochim. Biophys. Acta
802
245-252
1984
Rattus norvegicus
Kitani, T.; Fujisawa, H.
Influence of salts on the activity and the subunit structure of ornithine decarboxylase from rat liver
Biochim. Biophys. Acta
784
164-167
1984
Rattus norvegicus
Barnett, G.R.; Kazarinoff, M.N.
Purification and properties of ornithine decarboxylase from Physarum polycephalum
J. Biol. Chem.
259
179-183
1984
Physarum polycephalum
Kyriakidis, D.A.; Heller, J.S.; Canellakis, E.S.
Purification of ornithine decarboxylase antizymes (Escherichia coli)
Methods Enzymol.
94
193-199
1983
Escherichia coli
Hayashi, S.I.; Fujita, K.
Antizyme and antizyme inhibitor of ornithine decarboxylase (rat liver)
Methods Enzymol.
94
185-193
1983
Rattus norvegicus
Kyriakidis, D.A.; Panagiotidis, C.A.; Georgatsos, J.G.
Ornithine decarboxylase (germinated barley seeds)
Methods Enzymol.
94
162-166
1983
Hordeum vulgare
-
Seely, J.E.; Pegg, A.E.
Ornithine decarboxylase (mouse kidney)
Methods Enzymol.
94
158-161
1983
Mus musculus
Hayashi, S.I.; Kameji, T.
Ornithine decarboxylase (rat liver)
Methods Enzymol.
94
154-158
1983
Rattus norvegicus
Mitchell, J.L.A.
Ornithine decarboxylase and the ornithine decarboxylase-modifying protein of Physarum polycephalum
Methods Enzymol.
94
140-146
1983
Physarum polycephalum
Tyagi, A.K.; Tabor, C.W.; Tabor, H.
Ornithine decarboxylase (Saccharomyces cerevisiae)
Methods Enzymol.
94
135-139
1983
Saccharomyces cerevisiae
Morris, D.R.; Boeker, E.A.
Biosynthetic and biodegradative ornithine and arginine decarboxylases from Escherichia coli
Methods Enzymol.
94
125-134
1983
Escherichia coli
Isomaa, V.V.; Pajunen, A.E.I.; Bardin, C.W.; Jaenne, O.A.
Ornithine decarboxylase in mouse kidney. Purification, characterization, and radioimmunological determination of the enzyme protein
J. Biol. Chem.
258
6735-6740
1983
Mus musculus
Paulin, L.; Poesoe, H.
Ornithine decarboxylase activity from an extremely thermophilic bacterium, Clostridium thermohydrosulfuricum
Biochim. Biophys. Acta
742
197-205
1983
Thermoanaerobacter thermohydrosulfuricus
Kitani, T.; Fujisawa, H.
Effects of detergent on ornithine decarboxylase from rat liver. Stabilization and renaturation
Eur. J. Biochem.
119
177-181
1981
Rattus norvegicus
Guirard, B.M.; Snell, E.E.
Purification and properties of ornithine decarboxylase from Lactobacillus sp. 30a
J. Biol. Chem.
255
5960-5964
1980
Lactobacillus sp.
Ono, M.; Inoue, H.; Suzuki, F.; Takeda, Y.
Studies on ornithine decarboxylase from the liver of thioacetamide-treated rats
Biochim. Biophys. Acta
284
285-297
1972
Rattus norvegicus
Hu, Y.W.; Brosnan, M.E.
Properties of ornithine decarboxylase-antizyme from mammary gland of lactating rats
Arch. Biochem. Biophys.
254
637-641
1987
Rattus norvegicus
McCann, P.P.; Bacchi, C.J.; Hanson, W.L.; Nathan, H.C.; Hutner, S.H.; Sjoerdsma, A.
Methods for the study of the treatment of protozoan diseases by inhibitors of ornithine decarboxylase
Methods Enzymol.
94
209-213
1983
Eimeria tenella, Trypanosoma brucei
Kuehn, G.D.; Atmar, V.; Daniels, G.R.
Polyamine-dependent protein kinase from the slime mold Physarum polycephalum
Methods Enzymol.
94
147-154
1983
Physarum polycephalum, Rattus norvegicus
Momany, C.; Ernst, S.; Ghosh, R.; Chang, N.L.; Hackert, M.L.
Crystallographic structure of a PLP-dependent ornithine decarboxylase from Lactobacillus 30a to 3.0 A resolution
J. Mol. Biol.
252
643-655
1995
Lactobacillus sp.
Arteaga-Nieto, P.; Villagomez-Castro, J.C.; Calvo-Mendez, C.; Lopez-Romero, E.
Partial purification and characterization of ornithine decarboxylase from Entamoeba histolytica
Int. J. Parasitol.
26
253-260
1996
Entamoeba histolytica
Niemann, G.; von Besser, H.; Walter, R.D.
Panagrellus redivivus ornithine decarboxylase: structure of the gene, expression in Escherichia coli and characterization of the recombinant protein
Biochem. J.
317
135-140
1996
Panagrellus redivivus
Brooks, H.B.; Phillips, M.A.
Characterization of the reaction mechanism for Trypanosoma brucei ornithine decarboxylase by multiwavelength stopped-flow spectroscopy
Biochemistry
36
15147-15155
1997
Trypanosoma brucei
Oliveira, M.A.; Carroll, D.; Davidson, L.; Momany, C.; Hackert, M.L.
The GTP effector site of ornithine decarboxylase from Lactobacillus 30a: kinetic and structural characterization
Biochemistry
36
16147-16154
1997
Lactobacillus sp.
Hietala, O.A.; Yum, K.Y.; Pilon, J.; O'Donnell, K.; Holroyde, C.P.; Kline, I.; Reichard, G.A.; Litwin, S.; Gilmour, S.K.; O'Brien, T.G.
Properties of ornithine decarboxylase in human colorectal adenocarcinomas
Cancer Res.
50
2088-2094
1990
Homo sapiens
Assaraf, Y.G.; Kahana, C.; Spira, D.T.; Bachrach, U.
Plasmodium falciparum: purification, properties, and immunochemical study of ornithine decarboxylase, the key enzyme in polyamine biosynthesis
Exp. Parasitol.
67
20-30
1988
Plasmodium falciparum, Plasmodium falciparum FCR 3TC
Miyamoto, K.; Oka, T.; Fujii, T.; Yamaji, M.; Minami, H.; Nakabou, Y.; Hagihira, H.
Purification and some properties of rat intestinal ornithine decarboxylase
J. Biochem.
106
167-171
1989
Rattus norvegicus
Poulin, R.; Lu, L.; Ackermann, B.; Bey, P.; Pegg, A.E.
Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by a alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites
J. Biol. Chem.
267
150-158
1992
Mus musculus
Schaeffer, J.M.; Donatelli, M.R.
Characterization of a high affinity membrane-associated ornithine decarboxylase from the free-living nematode Caenorhabditis elegans
Biochem. J.
270
599-604
1990
Caenorhabditis elegans, Haemonchus contortus
Yarlett, N.; Goldberg, B.; Moharrami, M.A.; Bacchi, C.J.
Trichomonas vaginalis: characterization of ornithine decarboxylase
Biochem. J.
293
487-493
1993
Trichomonas vaginalis
von Besser, H.; Niemann, G.; Domdey, B.; Walter, R.D.
Molecular cloning and characterization of ornithine decarboxylase cDNA of the nematode Panagrellus redivivus
Biochem. J.
308
635-640
1995
Panagrellus redivivus
Klein, R.D.; Favreau, M.A.; Alexander-Bowman, S.J.; Nulf, S.C.; Vanover, L.; Winterrowd, C.A.; Yarlett, N.; Martinez, M.; Keithly, J.S.; Zantello, M.R.; Thomas, E.M.; Geary, T.G.
Haemonchus contortus: cloning and functional expression of a cDNA encoding ornithine decarboxylase and development of a screen for inhibitors
Exp. Parasitol.
87
171-184
1997
Haemonchus contortus (O76203), Haemonchus contortus
Coleman, C.S.; Stanley, B.A.; Pegg, A.E.
Effect of mutations at active site residues on the activity of ornithine decarboxylase and its inhibition by active site-directed irreversible inhibitors
J. Biol. Chem.
268
24572-24579
1993
Mus musculus
Fonzi, W.A.
Biochemical and genetic characterization of the structure of yeast ornithine decarboxylase
Biochem. Biophys. Res. Commun.
162
1409-1416
1989
Saccharomyces cerevisiae
Baby, T.G.; Hayashi, S.
Hepatic ornithine decarboxylase from the frog, Rana negromaculata: dietary induction, purification and some properties
Comp. Biochem. Physiol. B
99
151-156
1991
Mus musculus, Pelophylax nigromaculatus
Eichler, W.
Properties of purified L-ornithine decarboxylase (EC 4.1.1.17) from Tetrahymena thermophila
J. Protozool.
36
577-582
1989
Tetrahymena thermophila
Moyano, N.; Frydman, J.; Buldain, G.; Ruiz, O.; Frydman, R.B.
Inhibition of ornithine decarboxylase by the isomers of 1,4-dimethylputrescine
J. Med. Chem.
33
1969-1974
1990
Rattus norvegicus
Grishin, N.V.; Osterman, A.L.; Goldsmith, E.J.; Phillips, M.A.
Crystallization and preliminary X-ray studies of ornithine decarboxylase from Trypanosoma brucei
Proteins Struct. Funct. Genet.
24
272-273
1996
Trypanosoma brucei
Havis, N.D.; Walters, D.R.
In vitro effects of the polyamine biosynthesis inhibitor, alpha-difluoromethylornithine, on ornithine decarboxylase activities from three plant pathogenic fungi
Lett. Appl. Microbiol.
14
244-246
1992
Pyrenophora avenae, Pyricularia oryzae, Uromyces viciae-fabae
-
Steven, F.S.; Williams, L.A.; Warne, P.; Tucker, D.F.
Fluorescent location of ornithine decarboxylase employing derivatives of the specific inhibitor alpha-difluoromethyl ornithine
J. Enzyme Inhib.
3
133-143
1989
Homo sapiens
Halmekyto, M.; Alhonen, L.; Wahlfors, J.; Sinervirta, R.; Eloranta, T.; Janne, J.
Characterization of a transgenic mouse line over-expressing the human ornithine decarboxylase gene
Biochem. J.
15
895-898
1991
Homo sapiens
Fozard, J.R.; Part, M.L.
Methods for the study of the experimental interruption of pregnancy by ornithine decarboxylase inhibitors
Methods Enzymol.
94
213-216
1983
Mus musculus
Persson, L.; Rosengren, E.; Sundler, F.; Uddman, R.
Immunocytochemical localization of ornithine decarboxylase
Methods Enzymol.
94
166-169
1983
Mus musculus, Rattus norvegicus
Zagon, I.S.; Seely, J.E.; Pegg, A.E.
Autoradiographic localization of ornithine decarboxylase
Methods Enzymol.
94
169-176
1983
Mus musculus
Vitali, J.; Carroll, D.; Chaudhry, R.G.; Hackert, M.L.
Three-dimensional structure of the Gly121Tyr dimeric form of ornithine decarboxylase from Lactobacillus 30a
Acta Crystallogr. Sect. D
55
1978-1985
1999
Lactobacillus sp. 30a
Bachrach, U.; Wang, Y.C.
Cancer therapy and prevention by green tea: role of ornithine decarboxylase
Amino Acids
22
1-13
2002
Homo sapiens
Bertoldi, M.; Carbone, V.; Borri Voltattorni, C.
Ornithine and glutamate decarboxylases catalyze an oxidative deamination of their a-methyl substrates
Biochem. J.
342
509-512
1999
Lactobacillus sp. 30a
-
Krause, T.; Luersen, K.; Wrenger, C.; Gilberger, T.W.; Muller, S.; Walter, R.D.
The ornithine decarboxylase domain of the bifunctional ornithine decarboxylase/S-adenosylmethionine decarboxylase of Plasmodium falciparum: recombinant expression and catalytic properties of two different constructs
Biochem. J.
352
287-292
2000
Plasmodium falciparum
Lee, Y.S.; Cho, Y.D.
Identification of essential active-site residues in ornithine decarboxylase of Nicotiana glutinosa decarboxylating both L-ornithine and L-lysine
Biochem. J.
360
657-665
2001
Nicotiana glutinosa (Q9FPK5), Nicotiana glutinosa
Qu, N.; Ignatenko, N.A.; Yamauchi, P.; Stringer, D.E.; Levenson, C.; Shannon, P.; Perrin, S.; Gerner, E.W.
Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine
Biochem. J.
375
465-470
2003
Homo sapiens
Birkholtz, L.M.; Wrenger, C.; Joubert, F.; Wells, G.A.; Walter, R.D.; Louw, A.I.
Parasite-specific inserts in the bifunctional S-adenosylmethionine decarboxylase/ornithine decarboxylase of Plasmodium falciparum modulate catalytic activities and domain interactions
Biochem. J.
377
439-448
2004
Plasmodium falciparum (Q9U8D4), Plasmodium falciparum
Osterman, A.L.; Brooks, H.B.; Jackson, L.; Abbott, J.J.; Phillips, M.A.
Lysine-69 plays a key role in catalysis by ornithine decarboxylase through acceleration of the Schiff base formation, decarboxylation, and product release steps
Biochemistry
38
11814-11826
1999
Trypanosoma brucei
Jackson, L.K.; Brooks, H.B.; Osterman, A.L.; Goldsmith, E.J.; Phillips, M.A.
Altering the reaction specificity of eukaryotic ornithine decarboxylase
Biochemistry
39
11247-11257
2000
Trypanosoma brucei (P07805), Trypanosoma brucei
Myers, D.P.; Jackson, L.K.; Ipe, V.G.; Murphy, G.E.; Phillips, M.A.
Long-range interactions in the dimer interface of ornithine decarboxylase are important for enzyme function
Biochemistry
40
13230-13236
2001
Trypanosoma brucei (P07805), Trypanosoma brucei
Jackson, L.K.; Brooks, H.B.; Myers, D.P.; Phillips, M.A.
Ornithine decarboxylase promotes catalysis by binding the carboxylate in a buried pocket containing phenylalanine 397
Biochemistry
42
2933-2940
2003
Trypanosoma brucei (P07805)
Shantz, L.M.; Guo, Y.; Sawicki, J.A.; Pegg, A.E.; O'Brien, T.G.
Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation
Carcinogenesis
23
657-664
2002
Mus musculus
Arteaga-Nieto, P.; Lopez-Romero, E.; Teran-Figueroa, Y.; Cano-Canchola, C.; Luna Arias, J.P.; Flores-Carreon, A.; Calvo-Mendez, C.
Entamoeba histolytica: purification and characterization of ornithine decarboxylase
Exp. Parasitol.
101
215-222
2002
Entamoeba histolytica
Lee, Y.S.; Cho, Y.D.
Comparison of biochemical and immunological properties between rat and Nicotiana glutinosa ornithine decarboxylase
J. Biochem. Mol. Biol.
34
408-414
2001
Rattus norvegicus (P09057), Nicotiana glutinosa (Q9FPK5)
-
Lee, Y.S.; Cho, Y.D.
Mutation of cysteine-115 to alanine in Nicotiana glutinosa ornithine decarboxylase reduces enzyme activity
J. Biochem. Mol. Biol.
34
472-477
2001
Nicotiana glutinosa (Q9FPK5)
-
Wrenger, C.; Luersen, K.; Krause, T.; Muller, S.; Walter, R.D.
The Plasmodium falciparum bifunctional ornithine decarboxylase, S-adenosyl-L-methionine decarboxylase, enables a well balanced polyamine synthesis without domain-domain interaction
J. Biol. Chem.
276
29651-29656
2001
Plasmodium falciparum
Bauer, P.M.; Buga, G.M.; Fukuto, J.M.; Pegg, A.E.; Ignarro, L.J.
Nitric oxide inhibits ornithine decarboxylase via S-nitrosylation of cysteine 360 in the active site of the enzyme
J. Biol. Chem.
276
34458-34464
2001
Rattus norvegicus
Jackson, L.K.; Goldsmith, E.J.; Phillips, M.A.
X-ray structure determination of Trypanosoma brucei ornithine decarboxylase bound to D-ornithine and to G418: insights into substrate binding and ODC conformational flexibility
J. Biol. Chem.
278
22037-22043
2003
Trypanosoma brucei
Almrud, J.J.; Oliveira, M.A.; Kern, A.D.; Grishin, N.V.; Phillips, M.A.; Hackert, M.L.
Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding
J. Mol. Biol.
295
7-16
2000
Homo sapiens (P11926), Homo sapiens
Svechnikov, K.; Ritzen, E.M.; Holst, M.
Androgen and estrogen stimulation of ornithine decarboxylase activity in mouse kidney
J. Steroid Biochem. Mol. Biol.
75
329-333
2001
Mus musculus
Bartolome, J.V.; Wang, S.; Greer, N.L.; Schanberg, S.M.
Glucocorticoid regulation of ornithine decarboxylase in the postnatal rat lung
Life Sci.
64
895-904
1999
Rattus norvegicus
Seidel, E.R.; Ragan, V.; Liu, L.
Peroxynitrite inhibits the activity of ornithine decarboxylase
Life Sci.
68
1477-1483
2001
Rattus norvegicus
Pantazaki, A.A.; Anagnostopoulos, C.G.; Lioliou, E.E.; Kyriakidis, D.A.
Characterization of ornithine decarboxylase and regulation by its antizyme in Thermus thermophilus
Mol. Cell. Biochem.
195
55-64
1999
Escherichia coli, Thermus thermophilus
Wallstrom, E.L.; Persson, L.
No role of the 5' untranslated region of ornithine decarboxylase mRNA in the feedback control of the enzyme
Mol. Cell. Biochem.
197
71-78
1999
Homo sapiens
Babu, G.N.; Sailor, K.A.; Beck, J.; Sun, D.; Dempsey, R.J.
Ornithine decarboxylase activity in in vivo and in vitro models of cerebral ischemia
Neurochem. Res.
28
1851-1857
2003
Rattus norvegicus
Theiss, C.; Bohley, P.; Voigt, J.
Regulation by polyamines of ornithine decarboxylase activity and cell division in the unicellular green alga Chlamydomonas reinhardtii
Plant Physiol.
128
1470-1479
2002
Chlamydomonas reinhardtii
Bernet, E.; Claparols, I.; Dondini, L.; Santos, M.A.; Serafini-Fracassini, D.; Torne, J.M.
Changes in polyamine content, arginine and ornithine decarboxylases and transglutaminase activities during light/dark phases (of initial differentiation) in maize calluses and their chloroplasts
Plant Physiol. Biochem.
37
899-909
1999
Zea mays
-
Tassoni, A.; Fornale, S.; Bagni, N.
Putative ornithine decarboxylase activity in Arabidopsis thaliana: inhibition and intracellular localisation
Plant Physiol. Biochem.
41
871-875
2003
Arabidopsis thaliana
-
Birkholtz, L.; Joubert, F.; Neitz, A.W.; Louw, A.I.
Comparative properties of a three-dimensional model of Plasmodium falciparum ornithine decarboxylase
Proteins
50
464-473
2003
Plasmodium falciparum
Kern, A.D.; Oliveira, M.A.; Coffino, P.; Hackert, M.L.
Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases
Structure Fold. Des.
7
567-581
1999
Mus musculus
Gaboriau, F.; Havouis, R.; Groussard, K.; Moulinoux, J.P.; Lescoat, G.
Measurement of ornithine decarboxylase activity in cell extracts using mass spectrometry detection of dansylated putrescine
Anal. Biochem.
341
385-387
2005
Rattus norvegicus
Cardoso, V.V.; Prestes, P.R.; Casali, E.A.; Moreira, J.C.; Oliveira, A.K.
Ornithine decarboxylase activity during the development of Anastrepha fraterculus (Diptera, Tephritidae)
Arch. Insect Biochem. Physiol.
57
151-159
2004
Anastrepha fraterculus
Shantz, L.M.
Transcriptional and translational control of ornithine decarboxylase during Ras transformation
Biochem. J.
377
257-264
2004
Mus musculus
Jackson, L.K.; Baldwin, J.; Akella, R.; Goldsmith, E.J.; Phillips, M.A.
Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase
Biochemistry
43
12990-12999
2004
Trypanosoma brucei (P07805), Trypanosoma brucei
Chabanon, H.; Aubel, C.; Larvaron, P.; Villard, C.; Carraro, V.; Brachet, P.
Ornithine decarboxylase activity is inhibited by the polyamine precursor amino acids at the protein stability level in Caco-2 cells
Biochim. Biophys. Acta
1723
74-81
2005
Homo sapiens
Stabellini, G.; Brugnoli, F.; Calastrini, C.; Vizzotto, L.; Vertemati, M.; Baroni, T.; Caramelli, E.; Marinucci, L.; Pellati, A.; Bertagnolo, V.
Ornithine decarboxylase, polyamines and CD11b expression in HL-60 cells during differentiation induced by retinoic acid
Biomed. Pharmacother.
58
401-406
2004
Homo sapiens
Shon, Y.H.; Nam, K.S.
Inhibition of cytochrome P450 isozymes and ornithine decarboxylase activities by polysaccharides from soybeans fermented with Phellinus igniarius or Agrocybe cylindracea
Biotechnol. Lett.
26
159-163
2004
Mus musculus
Linsalata, M.; Russo, F.; Berloco, P.; Caruso, M.L.; Matteo, G.D.; Cifone, M.G.; Simone, C.D.; Ierardi, E.; Di Leo, A.
The influence of Lactobacillus brevis on ornithine decarboxylase activity and polyamine profiles in Helicobacter pylori-infected gastric mucosa
Helicobacter
9
165-172
2004
Homo sapiens
Fogel, W.A.; Dudkowska, M.; Wagner, W.; Grzelakowska-Sztabert, B.; Manteuffel-Cymborowska, M.
Ornithine and histidine decarboxylase: Activities in hypertrophic and hyperplastic mouse kidney
Inflamm. Res.
54
S62-S63
2005
Mus musculus
-
Yamaguchi, Y.; Takatsuka, Y.; Matsufuji, S.; Murakami, Y.; Kamio, Y.
Characterization of a counterpart to mammalian ornithine decarboxylase antizyme in prokaryotes
J. Biol. Chem.
281
3995-4001
2005
Mus musculus
Hao, Y.J.; Kitashiba, H.; Honda, C.; Nada, K.; Moriguchi, T.
Expression of arginine decarboxylase and ornithine decarboxylase genes in apple cells and stressed shoots
J. Exp. Bot.
56
1105-1115
2005
Malus domestica (Q5R1Y4), Malus domestica
Schipper, R.G.; Cuijpers, V.M.; De Groot, L.H.; Thio, M.; Verhofstad, A.A.
Intracellular localization of ornithine decarboxylase and its regulatory protein, antizyme-1
J. Histochem. Cytochem.
52
1259-1266
2004
Homo sapiens
Levin, V.A.; Jochec, J.L.; Shantz, L.M.; Koch, P.E.; Pegg, A.E.
Tissue-based assay for ornithine decarboxylase to identify patients likely to respond to difluoromethylornithine
J. Histochem. Cytochem.
52
1467-1474
2004
Homo sapiens
Young, L.; Salomon, R.; Au, W.; Allan, C.; Russell, P.; Dong, Q.
Ornithine decarboxylase (ODC) expression pattern in human prostate tissues and ODC transgenic mice
J. Histochem. Cytochem.
54
223-229
2006
Homo sapiens
Theiss, C.; Bohley, P.; Bisswanger, H.; Voigt, J.
Uptake of polyamines by the unicellular green alga Chlamydomonas reinhardtii and their effect on ornithine decarboxylase activity
J. Plant Physiol.
161
3-14
2004
Chlamydomonas reinhardtii
Voigt, J.; Fausel, M.; Bohley, P.; Adam, K.H.; Marquardt, O.
Structure and expression of the ornithine decarboxylase gene of Chlamydomonas reinhardtii
Microbiol. Res.
159
403-417
2004
Chlamydomonas reinhardtii (Q70GM6), Chlamydomonas reinhardtii
Bachmann, A.S.; Patil, S.S.
Characterization of ornithine decarboxylase from Pseudomonas syringae pv. phaseolicola and its inhibition by phaseolotoxin
Physiol. Mol. Plant Pathol.
63
57-63
2004
Pseudomonas savastanoi pv. phaseolicola
-
Tian, H.; Liu, X.; Zhang, B.; Sun, Q.; Sun, D.
Adenovirus-mediated expression of both antisense ornithine decarboxylase and S-adenosylmethionine decarboxylase inhibits lung cancer cell growth
Acta Biochim. Biophys. Sin.
39
423-430
2007
Homo sapiens
Bastida, C.M.; Cremades, A.; Castells, M.T.; Lopez-Contreras, A.J.; Lopez-Garcia, C.; Sanchez-Mas, J.; Penafiel, R.
Sexual dimorphism of ornithine decarboxylase in the mouse adrenal: influence of polyamine deprivation on catecholamine and corticoid levels
Am. J. Physiol. Endocrinol. Metab.
292
E1010-E1017
2007
Mus musculus (P00860), Mus musculus
Shantz, L.M.; Levin, V.A.
Regulation of ornithine decarboxylase during oncogenic transformation: mechanisms and therapeutic potential
Amino Acids
33
213-223
2007
Homo sapiens, Mus musculus, Rattus norvegicus
Hsu, P.C.; Hour, T.C.; Liao, Y.F.; Hung, Y.C.; Liu, C.C.; Chang, W.H.; Kao, M.C.; Tsay, G.J.; Hung, H.C.; Liu, G.Y.
Increasing ornithine decarboxylase activity is another way of prolactin preventing methotrexate-induced apoptosis: crosstalk between ODC and BCL-2
Apoptosis
11
389-399
2006
Homo sapiens
Cardoso, V.V.; Prestes, P.R.; Moreira, J.C.; Oliveira, A.K.
Changes in ornithine decarboxylase activity in response to temperature stress and stimulation of juvenile hormone in Anastrepha fraterculus (Diptera, Tephritidae)
Arch. Insect. Biochem. Physiol.
62
176-185
2006
Anastrepha fraterculus
Frossard, M.L.; Seabra, S.H.; DaMatta, R.A.; de Souza, W.; de Mello, F.G.; Machado Motta, M.C.
An endosymbiont positively modulates ornithine decarboxylase in host trypanosomatids
Biochem. Biophys. Res. Commun.
343
443-449
2006
Angomonas deanei
Nilsson, T.; Bogdanovic, N.; Volkman, I.; Winblad, B.; Folkesson, R.; Benedikz, E.
Altered subcellular localization of ornithine decarboxylase in Alzheimers disease brain
Biochem. Biophys. Res. Commun.
344
640-646
2006
Homo sapiens
Dufe, V.T.; Ingner, D.; Heby, O.; Khomutov, A.R.; Persson, L.; Al-Karadaghi, S.
A structural insight into the inhibition of human and Leishmania donovani ornithine decarboxylases by 1-amino-oxy-3-aminopropane
Biochem. J.
405
261-268
2007
Leishmania donovani, Homo sapiens (P11926), Homo sapiens
Persson, L.
Ornithine decarboxylase and S-adenosylmethionine decarboxylase in trypanosomatids
Biochem. Soc. Trans.
35
314-317
2007
Crithidia fasciculata, Leishmania donovani, Leishmania sp., Phytomonas sp., Trypanosoma brucei, Trypanosoma cruzi, Phytomonas sp. T274
Ma, Q.; Wang, Y.; Gao, X.; Ma, Z.; Song, Z.
L-arginine reduces cell proliferation and ornithine decarboxylase activity in patients with colorectal adenoma and adenocarcinoma
Clin. Cancer Res.
13
7407-7412
2007
Homo sapiens
Chen, Y.; Weeks, R.S.; Burns, M.R.; Boorman, D.W.; Klein-Szanto, A.; OBrien, T.G.
Combination therapy with 2-difluoromethylornithine and a polyamine transport inhibitor against murine squamous cell carcinoma
Int. J. Cancer
118
2344-2349
2006
Mus musculus, Mus musculus FVB/N
Levin, V.A.; Jochec, J.L.; Shantz, L.M.; Aldape, K.D.
Relationship between ornithine decarboxylase levels in anaplastic gliomas and progression-free survival in patients treated with DFMO-PCV chemotherapy
Int. J. Cancer
121
2279-2283
2007
Homo sapiens
Hoeytoe, A.; Juutilainen, J.; Naarala, J.
Ornithine decarboxylase activity is affected in primary astrocytes but not in secondary cell lines exposed to 872 MHz RF radiation
Int. J. Radiat. Biol.
83
367-374
2007
Homo sapiens, Mus musculus, Rattus norvegicus
Pegg, A.E.
Regulation of ornithine decarboxylase
J. Biol. Chem.
281
14529-14532
2006
Mus musculus
Gemperlova, L.; Novakova, M.; Vankova, R.; Eder, J.; Cvikrova, M.
Diurnal changes in polyamine content, arginine and ornithine decarboxylase, and diamine oxidase in tobacco leaves
J. Exp. Bot.
57
1413-1421
2006
Nicotiana tabacum
De Las Rivas, B.; Carrascosa, A.V.; Munoz, R.
Gene cloning, expression, and functional characterization of an ornithine decarboxylase protein from Serratia liquefaciens IFI65
J. Microbiol. Biotechnol.
17
408-413
2007
Serratia liquefaciens (A4Q8H0), Serratia liquefaciens IFI65 (A4Q8H0), Serratia liquefaciens IFI65
Kawano, K.; Masuda, H.; Yano, M.; Kihara, K.; Sugimoto, A.; Azuma, H.
Altered nitric oxide synthase, arginase and ornithine decarboxylase activities, and polyamine synthesis in response to ischemia of the rabbit detrusor
J. Urol.
176
387-393
2006
Oryctolagus cuniculus
Vanisree, A.J.; Shyamaladevi, C.S.
The effect of N-acetylcysteine in combination with vitamin C on the activity of ornithine decarboxylase of lung carcinoma cells - in vitro
Life Sci.
79
654-659
2006
Homo sapiens
Saunders, L.R.; Verdin, E.
Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors
Mol. Cancer Ther.
5
2777-2785
2006
Homo sapiens
Miao, X.P.; Li, J.S.; Li, H.Y.; Zeng, S.P.; Zhao, Y.; Zeng, J.Z.
Expression of ornithine decarboxylase in precancerous and cancerous gastric lesions
World J. Gastroenterol.
13
2867-2871
2007
Homo sapiens
Ohtake, Y.; Maruko, A.; Ohishi, N.; Kawaguchi, M.; Satoh, T.; Ohkubo, Y.
Effect of retinoic acid on transglutaminase and ornithine decarboxylase activities during liver regeneration
Cell Biochem. Funct.
26
359-365
2008
Rattus norvegicus
Kanerva, K.; Makitie, L.T.; Pelander, A.; Heiskala, M.; Andersson, L.C.
Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase
Biochem. J.
409
187-192
2008
Homo sapiens
Burritt, D.J.
The polycyclic aromatic hydrocarbon phenanthrene causes oxidative stress and alters polyamine metabolism in the aquatic liverwort Riccia fluitans L
Plant Cell Environ.
31
1416-1431
2008
Riccia fluitans
Deng, W.; Jiang, X.; Mei, Y.; Sun, J.; Ma, R.; Liu, X.; Sun, H.; Tian, H.; Sun, X.
Role of ornithine decarboxylase in breast cancer
Acta Biochim. Biophys. Sin.
40
235-243
2008
Homo sapiens
Wei, L.H.; Yang, Y.; Wu, G.; Ignarro, L.J.
IL-4 and IL-13 upregulate ornithine decarboxylase expression by PI3K and MAP kinase pathways in vascular smooth muscle cells
Am. J. Physiol. Cell Physiol.
294
C1198-C1205
2008
Rattus norvegicus
Nasizadeh, S.; Thiman, L.; Persson, L.
Sequence elements essential for the rapid turnover of Crithidia fasciculata ornithine decarboxylase
Amino Acids
34
421-428
2008
Leishmania donovani (P27116), Leishmania donovani, Crithidia fasciculata (P90517), Crithidia fasciculata
Takeuchi, J.; Chen, H.; Hoyt, M.A.; Coffino, P.
Structural elements of the ubiquitin-independent proteasome degron of ornithine decarboxylase
Biochem. J.
410
401-407
2008
Mus musculus (P00860), Mus musculus
Snapir, Z.; Keren-Paz, A.; Bercovich, Z.; Kahana, C.
ODCp, a brain- and testis-specific ornithine decarboxylase paralogue, functions as an antizyme inhibitor, although less efficiently than AzI1
Biochem. J.
410
613-619
2008
Homo sapiens, Mus musculus
Snapir, Z.; Keren-Paz, A.; Bercovich, Z.; Kahana, C.
Antizyme-3 inhibits polyamine uptake and ornithine decarboxylase (ODC) activity, but does not stimulate ODC degradation
Biochem. J.
419
99-103
2008
Homo sapiens
Bekaert, M.; Ivanov, I.P.; Atkins, J.F.; Baranov, P.V.
Ornithine decarboxylase antizyme finder (OAF): fast and reliable detection of antizymes with frameshifts in mRNAs
BMC Bioinformatics
9
178
2008
Homo sapiens
Wei, G.; DeFeo, K.; Hayes, C.S.; Woster, P.M.; Mandik-Nayak, L.; Gilmour, S.K.
Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes
Cancer Res.
68
2214-2222
2008
Mus musculus
Svensson, K.J.; Welch, J.E.; Kucharzewska, P.; Bengtson, P.; Bjurberg, M.; Pahlman, S.; Ten Dam, G.B.; Persson, L.; Belting, M.
Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase
Cancer Res.
68
9291-9301
2008
Homo sapiens, Rattus norvegicus
Koomoa, D.L.; Yco, L.P.; Borsics, T.; Wallick, C.J.; Bachmann, A.S.
Ornithine decarboxylase inhibition by alpha-difluoromethylornithine activates opposing signaling pathways via phosphorylation of both Akt/protein kinase B and p27Kip1 in neuroblastoma
Cancer Res.
68
9825-9831
2008
Homo sapiens
Rounbehler, R.J.; Li, W.; Hall, M.A.; Yang, C.; Fallahi, M.; Cleveland, J.L.
Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma
Cancer Res.
69
547-553
2009
Homo sapiens
Hubner, R.A.; Muir, K.R.; Liu, J.F.; Logan, R.F.; Grainge, M.J.; Houlston, R.S.; Houlston, R.S.
Ornithine decarboxylase G316A genotype is prognostic for colorectal adenoma recurrence and predicts efficacy of aspirin chemoprevention
Clin. Cancer Res.
14
2303-2309
2008
Homo sapiens
Tang, Y.W.; Han, J.; McCormac, M.A.; Li, H.; Stratton, C.W.
Staphylococcus pseudolugdunensis sp. nov., a pyrrolidonyl arylamidase/ornithine decarboxylase-positive bacterium isolated from blood cultures
Diagn. Microbiol. Infect. Dis.
60
351-359
2008
Staphylococcus pseudolugdunensis, Staphylococcus pseudolugdunensis B006
Bordallo, J.; Secades, L.; Bordallo, C.; Cantabrana, B.; Sanchez, M.
Influence of gender and sex hormones on 5alpha-dihydrotestosterone elicited effect in isolated left atria of rats: role of beta-adrenoceptors and ornithine decarboxylase activity
Eur. J. Pharmacol.
604
103-110
2008
Rattus norvegicus
Rosas-Arreguin, P.; Arteaga-Nieto, P.; Reynoso-Orozco, R.; Villagomez-Castro, J.C.; Sabanero-Lopez, M.; Puebla-Perez, A.M.; Calvo-Mendez, C.
Bursera fagaroides, effect of an ethanolic extract on ornithine decarboxylase (ODC) activity in vitro and on the growth of Entamoeba histolytica
Exp. Parasitol.
119
398-402
2008
Entamoeba histolytica, Entamoeba histolytica HM 1:IMSS
Wu, F.; Gehring, H.
Structural requirements for novel coenzyme-substrate derivatives to inhibit intracellular ornithine decarboxylase and cell proliferation
FASEB J.
23
565-574
2008
Homo sapiens (P11926), Homo sapiens
Tang, H.; Ariki, K.; Ohkido, M.; Murakami, Y.; Matsufuji, S.; Li, Z.; Yamamura, K.
Role of ornithine decarboxylase antizyme inhibitor in vivo
Genes Cells
14
79-87
2009
Mus musculus
Loukanina, N.; Thorpe, T.A.
Arginine and ornithine decarboxylases in embryogenic and non-embryogenic carrot cell suspensions
In Vitro Cell. Dev. Biol. Plant
44
59-64
2008
Daucus carota
-
Boitz, J.M.; Yates, P.A.; Kline, C.; Gaur, U.; Wilson, M.E.; Ullman, B.; Roberts, S.C.
Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host
Infect. Immun.
77
756-763
2009
Leishmania donovani, Leishmania donovani LdBob
Ehrnstroem, R.A.; Bjursten, L.M.; Ljungberg, O.; Veress, B.; Haglund, M.E.; Lindstroem, C.G.; Andersson, T.
Dietary supplementation with carbonate increases expression of ornithine decarboxylase and proliferation in gastric mucosa in a rat model of gastric cancer
Int. J. Cancer
122
727-733
2008
Rattus norvegicus
Hoeytoe, A.; Sokura, M.; Juutilainen, J.; Naarala, J.
Radiofrequency radiation does not significantly affect ornithine decarboxylase activity, proliferation, or caspase-3 activity of fibroblasts in different physiological conditions
Int. J. Radiat. Biol.
84
727-733
2008
Mus musculus
Lafay, B.; Ruimy, R.; de Traubenberg, C.R.; Breittmayer, V.; Gauthier, M.J.; Christen, R.
Roseobacter algicola sp. nov., a new marine bacterium isolated from the phycosphere of the toxin-producing dinoflagellate Prorocentrum lima
Int. J. Syst. Bacteriol.
45
290-296
1995
no activity in Marinovum algicola, no activity in Marinovum algicola ATCC 51442
Ruiz-Ponte, C.; Cilia, V.; Lambert, C.; Nicolas, J.L.
Roseobacter gallaeciensis sp. nov., a new marine bacterium isolated from rearings and collectors of the scallop Pecten maximus
Int. J. Syst. Bacteriol.
48 Pt 2
537-542
1998
no activity in Phaeobacter gallaeciensis BS107
Lau, S.C.; Tsoi, M.M.; Li, X.; Plakhotnikova, I.; Wu, M.; Wong, P.K.; Qian, P.Y.
Loktanella hongkongensis sp. nov., a novel member of the alpha-Proteobacteria originating from marine biofilms in Hong Kong waters
Int. J. Syst. Evol. Microbiol.
54
2281-2284
2004
no activity in Loktanella hongkongensis
Lee, O.O.; Tsoi, M.M.; Li, X.; Wong, P.K.; Qian, P.Y.
Thalassococcus halodurans gen. nov., sp. nov., a novel halotolerant member of the Roseobacter clade isolated from the marine sponge Halichondria panicea at Friday Harbor, USA
Int. J. Syst. Evol. Microbiol.
57
1919-1924
2007
no activity in Thalassobius mediterraneus, no activity in Thalassobius mediterraneus XSM19, no activity in Thalassococcus halodurans, no activity in Thalassococcus halodurans UST050418-052, Shimia aestuarii, Shimia aestuarii JC2049
Yamaguchi, Y.; Takatsuka, Y.; Kamio, Y.
Two segments in bacterial antizyme P22 are essential for binding and enhance degradation of lysine/ornithine decarboxylase in Selenomonas ruminantium
J. Bacteriol.
190
442-446
2008
Selenomonas ruminantium
Porat, Z.; Landau, G.; Bercovich, Z.; Krutauz, D.; Glickman, M.; Kahana, C.
Yeast antizyme mediates degradation of yeast ornithine decarboxylase by yeast but not by mammalian proteasome: new insights on yeast antizyme
J. Biol. Chem.
283
4528-4534
2008
Saccharomyces cerevisiae
van Brummelen, A.C.; Olszewski, K.L.; Wilinski, D.; Llinas, M.; Louw, A.I.; Birkholtz, L.M.
Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome and metabolome analyses
J. Biol. Chem.
284
4635-4646
2008
Plasmodium falciparum
De Las Rivas, B.; Gonzalez, R.; Landete, J.M.; Munoz, R.
Characterization of a second ornithine decarboxylase isolated from Morganella morganii
J. Food Prot.
71
657-661
2008
Morganella morganii
Walckenaer, E.; Leflon-Guibout, V.; Nicolas-Chanoine, M.H.
How to identify Raoultella spp. including R. ornithinolytica isolates negative for ornithine decarboxylase? The reliability of the chromosomal bla gene
J. Microbiol. Methods
75
405-410
2008
Raoultella planticola, no activity in Raoultella ornithinolytica
Liao, Y.F.; Hung, H.C.; Hsu, P.C.; Kao, M.C.; Hour, T.C.; Tsay, G.J.; Liu, G.Y.
Ornithine decarboxylase interferes with macrophage-like differentiation and matrix metalloproteinase-9 expression by tumor necrosis factor alpha via NF-kappaB
Leuk. Res.
32
1124-1140
2008
Homo sapiens
Hsu, P.C.; Hung, H.C.; Liao, Y.F.; Liu, C.C.; Tsay, G.J.; Liu, G.Y.
Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells
Leuk. Res.
32
1530-1540
2008
Homo sapiens
Liao, Y.F.; Hung, H.C.; Hour, T.C.; Hsu, P.C.; Kao, M.C.; Tsay, G.J.; Liu, G.Y.
Curcumin induces apoptosis through an ornithine decarboxylase-dependent pathway in human promyelocytic leukemia HL-60 cells
Life Sci.
82
367-375
2008
Homo sapiens
Zhou, Y.; Ma, C.; Karmouch, J.; Arabi Katbi, H.; Liu, X.J.
An anti-apoptotic role for ornithine decarboxylase during oocyte maturation
Mol. Cell. Biol.
29
1786-1795
2009
Xenopus laevis
Park, J.H.; Lee, C.K.; Hwang, Y.S.; Park, K.K.; Chung, W.Y.
Hemin inhibits cyclooxygenase-2 expression through nuclear factor-kappa B activation and ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin
Mutat. Res.
642
68-73
2008
Mus musculus
Kim, J.H.; Kim, H.S.; Lee, Y.H.; Kim, Y.S.; Oh, H.W.; Joung, H.; Chae, S.K.; Suh, K.H.; Jeon, J.H.
Polyamine biosynthesis regulated by StARD expression plays an important role in potato wound periderm formation
Plant Cell Physiol.
49
1627-1632
2008
Solanum tuberosum
Jhingran, A.; Padmanabhan, P.K.; Singh, S.; Anamika, K.; Bakre, A.A.; Bhattacharya, S.; Bhattacharya, A.; Srinivasan, N.; Madhubala, R.
Characterization of the Entamoeba histolytica ornithine decarboxylase-like enzyme
PLoS Negl. Trop. Dis.
2
e115
2008
Entamoeba histolytica (Q58P26), Entamoeba histolytica
Ivanov, I.P.; Loughran, G.; Atkins, J.F.
uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs
Proc. Natl. Acad. Sci. USA
105
10079-10084
2008
Mus musculus
Bera, S.; Wallimann, T.; Ray, S.; Ray, M.
Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells
FEBS J.
275
5899-5909
2008
Mus musculus
Govoni, M.; Bonavita, F.; Shantz, L.M.; Guarnieri, C.; Giordano, E.
Overexpression of ornithine decarboxylase increases myogenic potential of H9c2 rat myoblasts
Amino Acids
38
541-547
2010
Rattus norvegicus
Maekitie, L.T.; Kanerva, K.; Polvikoski, T.; Paetau, A.; Andersson, L.C.
brain neurons express ornithine decarboxylase-activating antizyme inhibitor 2 with accumulation in Alzheimers disease
Brain Pathol.
20
571-580
2010
Homo sapiens
Zell, J.A.; Ziogas, A.; Ignatenko, N.; Honda, J.; Qu, N.; Bobbs, A.S.; Neuhausen, S.L.; Gerner, E.W.; Anton-Culver, H.
Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survival
Clin. Cancer Res.
15
6208-6216
2009
Homo sapiens
Grimminger, P.P.; Schneider, P.M.; Metzger, R.; Vallboehmer, D.; Danenberg, K.D.; Danenberg, P.V.; Hoelscher, A.H.; Brabender, J.
Ornithine decarboxylase mRNA expression in curatively resected non-small-cell lung cancer
Clin. Lung Cancer
11
114-119
2010
Homo sapiens
Porasuphatana, S.; Cao, G.L.; Tsai, P.; Tavakkoli, F.; Huwar, T.; Baillie, L.; Cross, A.S.; Shapiro, P.; Rosen, G.M.
Bacillus anthracis endospores regulate ornithine decarboxylase and inducible nitric oxide synthase through ERK1/2 and p38 mitogen-activated protein kinases
Curr. Microbiol.
61
567-573
2010
Mus musculus
Tuziak, S.M.; Moghadam, H.K.; Danzmann, R.G.
Genetic mapping of the ornithine decarboxylase (odc) gene complex in rainbow trout (Oncorhynchus mykiss)
Cytogenet. Genome Res.
125
279-285
2009
Oncorhynchus mykiss (C7BBC1), Oncorhynchus mykiss
Maekitie, L.T.; Kanerva, K.; Andersson, L.C.
Ornithine decarboxylase regulates the activity and localization of rhoA via polyamination
Exp. Cell Res.
315
1008-1014
2009
Rattus norvegicus
Teran-Figueroa, Y.; Arteaga-Nieto, P.; Bethancourt-Rodriguez, A.; Labra-Barrios, M.L.; Luna-Arias, J.P.; Flores-Carreon, A.; Cano-Canchola, C.; Lopez-Romero, E.; Calvo-Mendez, C.
Entamoeba histolytica, heterologous expression and in situ immunolocalization of ornithine decarboxylase (EhODC)
Exp. Parasitol.
123
99-104
2009
Entamoeba histolytica
Brown, I.; Halliday, S.; Greig, H.; Heys, S.D.; Wallace, H.M.; Schofield, A.C.
Genetic polymorphism in ornithine decarboxylase and risk of breast cancer
Fam. Cancer
8
307-311
2009
Homo sapiens
Ansari, K.M.; Das, M.
Skin tumor promotion by argemone oil/alkaloid in mice: evidence for enhanced cell proliferation, ornithine decarboxylase, cyclooxygenase-2 and activation of MAPK/NF-kappaB pathway
Food Chem. Toxicol.
48
132-138
2010
Mus musculus
Maekitie, L.T.; Kanerva, K.; Sankila, A.; Andersson, L.C.
High expression of antizyme inhibitor 2, an activator of ornithine decarboxylase in steroidogenic cells of human gonads
Histochem. Cell Biol.
132
633-638
2009
Homo sapiens
Geerts, D.; Koster, J.; Albert, D.; Koomoa, D.L.; Feith, D.J.; Pegg, A.E.; Volckmann, R.; Caron, H.; Versteeg, R.; Bachmann, A.S.
The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification
Int. J. Cancer
126
2012-2024
2010
Homo sapiens
Marcora, M.S.; Cejas, S.; Gonzalez, N.S.; Carrillo, C.; Algranati, I.D.
Polyamine biosynthesis in Phytomonas: Biochemical characterization of a very unstable ornithine decarboxylase
Int. J. Parasitol.
40
1389-1394
2010
Phytomonas sp., Phytomonas sp. Jma
Billaudel, B.; Taxile, M.; Ruffie, G.; Veyret, B.; Lagroye, I.
Effects of exposure to DAMPS and GSM signals on ornithine decarboxylase (ODC) activity: I. L-929 mouse fibroblasts
Int. J. Radiat. Biol.
85
510-518
2009
Mus musculus
Billaudel, B.; Taxile, M.; Poulletier de Gannes, F.; Ruffie, G.; Lagroye, I.; Veyret, B.
Effects of exposure to DAMPS and GSM signals on ornithine decarboxylase (ODC) activity: II. SH-SY5Y human neuroblastoma cells
Int. J. Radiat. Biol.
85
519-522
2009
Homo sapiens
Smithson, D.C.; Lee, J.; Shelat, A.A.; Phillips, M.A.; Guy, R.K.
Discovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylase
J. Biol. Chem.
285
16771-16781
2010
Trypanosoma brucei (P07805), Trypanosoma brucei
Cohavi, O.; Tobi, D.; Schreiber, G.
Docking of antizyme to ornithine decarboxylase and antizyme inhibitor using experimental mutant and double-mutant cycle data
J. Mol. Biol.
390
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Mus musculus
Ivanov, I.P.; Firth, A.E.; Atkins, J.F.
Recurrent emergence of catalytically inactive ornithine decarboxylase homologous forms that likely have regulatory function
J. Mol. Evol.
70
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Aedes aegypti, Ancylostoma ceylanicum, Anolis carolinensis, Anopheles gambiae, Aspergillus clavatus, Aspergillus fischeri, Aspergillus fumigatus, Aspergillus terreus, Bos taurus, Botrytis cinerea, Branchiostoma floridae, Caenorhabditis briggsae, Caenorhabditis elegans, Canis lupus familiaris, Ciona intestinalis, Coccidioides immitis, Culex pipiens, Dictyostelium discoideum, Drosophila melanogaster, Dugesia japonica, Fusarium oxysporum, Fusarium verticillioides, Gallus gallus, Gasterosteus aculeatus, Homo sapiens, Hydra vulgaris, Meyerozyma guilliermondii, Mus musculus, Nasonia vitripennis, Neurospora crassa, Parastagonospora nodorum, Petromyzon marinus, Rattus norvegicus, Schmidtea mediterranea, Takifugu rubripes, Tetraodon nigroviridis, Trypanosoma brucei, Uncinocarpus reesii, Xenopus laevis
Garcia-Jimenez, P.; Garcia-Maroto, F.; Garrido-Cardenas, J.A.; Ferrandiz, C.; Robaina, R.R.
Differential expression of the ornithine decarboxylase gene during carposporogenesis in the thallus of the red seaweed Grateloupia imbricata (Halymeniaceae)
J. Plant Physiol.
166
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2009
Grateloupia imbricata (C9W982), Grateloupia imbricata
Correa-Basurto, J.; Rodrguez-Paez, L.; Aguiar-Moreno, E.; Lopez-Sanchez, P.; Espinoza-Fonseca, L.; Wong, C.; Trujillo-Ferrara, J.
Computational and experimental evaluation of ornithine derivatives as ornithine decarboxylase inhibitors
Med. Chem. Res.
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2009
Rattus norvegicus
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Zhao, Y.J.; Zhang, W.H.; Xu, C.Q.; Li, H.Z.; Wang, L.N.; Li, H.; Sun, Y.H.; Lin, Y.; Han, L.P.; Zhang, L.; Tian, Y.; Wang, R.; Yang, B.F.; Li, W.M.
Involvement of the ornithine decarboxylase/polyamine system in precondition-induced cardioprotection through an interaction with PKC in rat hearts
Mol. Cell. Biochem.
332
135-144
2009
Rattus norvegicus
Choi, S.Y.; Park, H.Y.; Paek, A.; Kim, G.S.; Jeong, S.E.
Insect ornithine decarboxylase (ODC) complements SPE1 knock-out of yeast Saccharomyces cerevisiae
Mol. Cells
28
575-581
2009
Spodoptera litura (D0ENK2), Spodoptera litura
Matsuoka, Y.; Uehara, N.; Tsubura, A.
hnRNP U interacts with the c-Myc-Max complex on the E-box promoter region inducing the ornithine decarboxylase gene
Oncol. Rep.
22
249-255
2009
Rattus norvegicus
Tokuhiro, K.; Isotani, A.; Yokota, S.; Yano, Y.; Oshio, S.; Hirose, M.; Wada, M.; Fujita, K.; Ogawa, Y.; Okabe, M.; Nishimune, Y.; Tanaka, H.
OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse
PLoS Genet.
5
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2009
Mus musculus
Singh, A.; Nirala, N.; Das, S.; Narula, A.; Rajam, M.; Srivastava, P.
Overexpression of odc (ornithine decarboxylase) in Datura innoxia enhances the yield of scopolamine
Acta Physiol. Plant.
2011
1-7
2011
Mus musculus
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Lee, N.K.; Skinner, J.P.; Zajac, J.D.; MacLean, H.E.
Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation
Am. J. Physiol. Endocrinol. Metab.
301
E172-E179
2011
Mus musculus
Giordano, E.; Hillary, R.A.; Vary, T.C.; Pegg, A.E.; Sumner, A.D.; Caldarera, C.M.; Zhang, X.Q.; Song, J.; Wang, J.; Cheung, J.Y.; Shantz, L.M.
Overexpression of ornithine decarboxylase decreases ventricular systolic function during induction of cardiac hypertrophy
Amino Acids
42
507-518
2012
Mus musculus
Illingworth, C.; Michael, A.J.
Plant ornithine decarboxylase is not post-transcriptionally feedback regulated by polyamines but can interact with a cytosolic ribosomal protein S15 polypeptide
Amino Acids
42
519-527
2012
Arabidopsis thaliana
Aksyonova, G.E.; Logvinovich, O.S.; Fialkovskaya, L.A.; Afanasyev, V.N.; Ignatev, D.A.; Kolomiytseva, I.K.
Ornithine decarboxylase activity in rat organs and tissues under artificial hypobiosis
Biochemistry
75
1126-1131
2010
Rattus norvegicus
Fogle, E.J.; Toney, M.D.
Analysis of catalytic determinants of diaminopimelate and ornithine decarboxylases using alternate substrates
Biochim. Biophys. Acta
1814
1113-1119
2011
Saccharomyces cerevisiae, Saccharomyces cerevisiae WDHT668
Logvinovich, O.; Aksyonova, G.; Fialkovskaya, L.; Afanasyev, V.; Ignatev, D.; Kolomiytseva, I.; Fesenko, E.
Ornithine decarboxylase in the liver, spleen, and bone marrow of ground squirrels Spermophilus undulatus
Dokl. Biochem. Biophys.
433
216-218
2010
Urocitellus undulatus
Kucharzewska, P.; Welch, J.E.; Svensson, K.J.; Belting, M.
Ornithine decarboxylase and extracellular polyamines regulate microvascular sprouting and actin cytoskeleton dynamics in endothelial cells
Exp. Cell Res.
316
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2010
Homo sapiens, Mus musculus
Bonnin-Jusserand, M.; Grandvalet, C.; David, V.; Alexandre, H.
Molecular cloning, heterologous expression, and characterization of ornithine decarboxylase from Oenococcus oeni
J. Food Prot.
74
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2011
Oenococcus oeni
Romano, A.; Trip, H.; Lonvaud-Funel, A.; Lolkema, J.S.; Lucas, P.M.
Evidence of two functionally distinct ornithine decarboxylation systems in lactic acid bacteria
Appl. Environ. Microbiol.
78
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2012
Lactobacillus gasseri (A0A1V3Y1D0), Levilactobacillus brevis (H8ZI01), Lacticaseibacillus casei (Q038E5), Oenococcus oeni (Q5ZH57), Lacticaseibacillus casei ATCC 334 (Q038E5), Lactobacillus gasseri DSM 20243 (A0A1V3Y1D0), Oenococcus oeni IOEB 89006 (Q5ZH57)
Choi, H.; Kyeong, H.; Choi, J.; Kim, H.
Rational design of ornithine decarboxylase with high catalytic activity for the production of putrescine
Appl. Microbiol. Biotechnol.
98
7483-7490
2014
Escherichia coli (P21169), Escherichia coli
Chattopadhyay, M.K.; Fernandez, C.; Sharma, D.; McPhie, P.; Masison, D.C.
Yeast ornithine decarboxylase and antizyme form a 1:1 complex in vitro: purification and characterization of the inhibitory complex
Biochem. Biophys. Res. Commun.
406
177-182
2011
Saccharomyces cerevisiae
Ramos-Molina, B.; Lambertos, A.; Lopez-Contreras, A.J.; Penafiel, R.
Mutational analysis of the antizyme-binding element reveals critical residues for the function of ornithine decarboxylase
Biochim. Biophys. Acta
1830
5157-5165
2013
Mus musculus
Romano, A.; Trip, H.; Lolkema, J.S.; Lucas, P.M.
Three-component lysine/ornithine decarboxylation system in Lactobacillus saerimneri 30a
J. Bacteriol.
195
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2013
Ligilactobacillus saerimneri 30a (P43099), Ligilactobacillus saerimneri 30a
Lange, I.; Geerts, D.; Feith, D.J.; Mocz, G.; Koster, J.; Bachmann, A.S.
Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation
J. Mol. Biol.
426
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2014
Homo sapiens
Docimo, T.; Reichelt, M.; Schneider, B.; Kai, M.; Kunert, G.; Gershenzon, J.; DAuria, J.C.
The first step in the biosynthesis of cocaine in Erythroxylum coca: the characterization of arginine and ornithine decarboxylases
Plant Mol. Biol.
78
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2012
Erythroxylum coca (G4XUJ8), Erythroxylum coca
Preeti, R.J.; Tapas, S.; Kumar, P.; Madhubala, R.; Tomar, S.
Biochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolytica
PLoS Negl. Trop. Dis.
6
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2012
Entamoeba histolytica (Q58P26), Entamoeba histolytica
Liu, Y.C.; Hsu, D.H.; Huang, C.L.; Liu, Y.L.; Liu, G.Y.; Hung, H.C.
Determinants of the differential antizyme-binding affinity of ornithine decarboxylase
PLoS ONE
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e26835
2011
Homo sapiens
Preeti, A.R.; Tapas, S.; Kumar, P.; Madhubala, R.; Tomar, S.
Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution
PLoS ONE
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2013
Entamoeba histolytica (Q58P26), Entamoeba histolytica
De Oliveira, L.; Macedo, A.; Dos Santos, A.; Floh, E.
Polyamine levels, arginine and ornithine decarboxylase activity in embryogenic cultures of Araucaria angustifolia (Bert.) O. Kuntze
Acta Hortic.
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2015
Araucaria angustifolia
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Hayes, C.; DeFeo-Mattox, K.; Woster, P.; Gilmour, S.
Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites
Amino Acids
46
543-552
2014
Mus musculus (P00860), Mus musculus, Mus musculus C57BL/6 (P00860)
Kanerva, K.; Maekitie, L.T.; Pelander, A.; Heiskala, M.; Andersson, L.C.
Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase
Biochem. J.
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2008
Homo sapiens
Takeuchi, J.; Chen, H.; Hoyt, M.A.; Coffino, P.
Structural elements of the ubiquitin-independent proteasome degron of ornithine decarboxylase
Biochem. J.
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2008
Mus musculus (P00860)
Snapir, Z.; Keren-Paz, A.; Bercovich, Z.; Kahana, C.
ODCp, a brain- and testis-specific ornithine decarboxylase paralogue, functions as an antizyme inhibitor, although less efficiently than AzI1
Biochem. J.
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2008
Homo sapiens (P11926)
Kmiec, K.; Sempruch, C.; Chrzanowski, G.; Czerniewicz, P.
The effect of Tetraneura ulmi L. galling process on the activity of amino acid decarboxylases and the content of biogenic amines in Siberian elm tissues
Bull. Entomol. Res.
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2018
Ulmus pumila
Singh, K.; Coburn, L.A.; Asim, M.; Barry, D.P.; Allaman, M.M.; Shi, C.; Washington, M.K.; Luis, P.B.; Schneider, C.; Delgado, A.G.; Piazuelo, M.B.; Cleveland, J.L.; Gobert, A.P.; Wilson, K.T.
Ornithine decarboxylase in macrophages exacerbates colitis and promotes colitis-associated colon carcinogenesis by impairing M1 immune responses
Cancer Res.
78
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2018
Mus musculus (P00860), Homo sapiens (P11926), Homo sapiens
Ohtake, Y.; Maruko, A.; Ohishi, N.; Kawaguchi, M.; Satoh, T.; Ohkubo, Y.
Effect of retinoic acid on transglutaminase and ornithine decarboxylase activities during liver regeneration
Cell Biochem. Funct.
26
359-365
2008
Rattus norvegicus (P09057), Rattus norvegicus Wistar (P09057)
Fonseca, M.S.; Comini, M.A.; Resende, B.V.; Santi, A.M.; Zoboli, A.P.; Moreira, D.S.; Murta, S.M.
Ornithine decarboxylase or gamma-glutamylcysteine synthetase overexpression protects Leishmania (Vianna) guyanensis against antimony
Exp. Parasitol.
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Leishmania guyanensis (A0A1E1IR91), Leishmania guyanensis, Leishmania guyanensis BR/1985/M9945 (A0A1E1IR91)
Loukanina, N.; Thorpe, T.A.
Arginine and ornithine decarboxylases in embryogenic and non-embryogenic carrot cell suspensions
In Vitro Cell. Dev. Biol. Plant
44
59-64
2008
Daucus carota
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Chen, Y.; Weeks, R.S.; Burns, M.R.; Boorman, D.W.; Klein-Szanto, A.; O'Brien, T.G.
Combination therapy with 2-difluoromethylornithine and a polyamine transport inhibitor against murine squamous cell carcinoma
Int. J. Cancer
118
2344-2349
2006
Mus musculus (P00860), Mus musculus C57BL/6J (P00860)
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Ehrnstroem, R.A.; Bjursten, L.M.; Ljungberg, O.; Veress, B.; Haglund, M.E.; Lindstroem, C.G.; Andersson, T.
Dietary supplementation with carbonate increases expression of ornithine decarboxylase and proliferation in gastric mucosa in a rat model of gastric cancer
Int. J. Cancer
122
727-733
2008
Rattus norvegicus (P09057), Rattus norvegicus, Rattus norvegicus Wistar (P09057)
Kumar, R.; Rafia, S.; Saran, S.
Cloning, expression and characterization of the ornithine decarboxylase gene from Dictyostelium discoideum
Int. J. Dev. Biol.
58
669-676
2014
Dictyostelium discoideum (Q54UF3), Dictyostelium discoideum
Yadav, A.; Amit, A.; Chaudhary, R.; Chandel, A.S.; Mahantesh, V.; Suman, S.S.; Singh, S.K.; Dikhit, M.R.; Ali, V.; Rabidas, V.; Pandey, K.; Kumar, A.; Das, P.; Bimal, S.
Leishmania donovani impairment of the cellular immune response against recombinant ornithine decarboxylase protein as a possible evasion strategy of Leishmania in visceral leishmaniasis
Int. J. Parasitol.
45
33-42
2015
Leishmania donovani (P27116), Leishmania donovani
Lenis, Y.Y.; Johnson, G.A.; Wang, X.; Tang, W.W.; Dunlap, K.A.; Satterfield, M.C.; Wu, G.; Hansen, T.R.; Bazer, F.W.
Functional roles of ornithine decarboxylase and arginine decarboxylase during the peri-implantation period of pregnancy in sheep
J. Anim. Sci. Biotechnol.
9
10
2018
Ovis aries (W5Q1G7), Ovis aries, Ovis aries Rambouillet (W5Q1G7)
Porat, Z.; Landau, G.; Bercovich, Z.; Krutauz, D.; Glickman, M.; Kahana, C.
Yeast antizyme mediates degradation of yeast ornithine decarboxylase by yeast but not by mammalian proteasome - new insights on yeast antizyme
J. Biol. Chem.
283
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2008
Saccharomyces cerevisiae (P08432), Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741 (P08432)
Tassoni, A.; Awad, N.; Griffiths, G.
Effect of ornithine decarboxylase and norspermidine in modulating cell division in the green alga Chlamydomonas reinhardtii
Plant Physiol. Biochem.
123
125-131
2018
Chlamydomonas reinhardtii (A8J7E8), Chlamydomonas reinhardtii, Chlamydomonas reinhardtii CC-125 (A8J7E8)
Gamat, M.; Malinowski, R.L.; Parkhurst, L.J.; Steinke, L.M.; Marker, P.C.
Ornithine decarboxylase activity is required for prostatic budding in the developing mouse prostate
PLoS ONE
10
e0139522
2015
Mus musculus, Mus musculus C57/BL6
Kim, H.I.; Schultz, C.R.; Buras, A.L.; Friedman, E.; Fedorko, A.; Seamon, L.; Chandramouli, G.V.R.; Maxwell, G.L.; Bachmann, A.S.; Risinger, J.I.
Ornithine decarboxylase as a therapeutic target for endometrial cancer
PLoS ONE
12
e0189044
2017
Homo sapiens (P11926), Homo sapiens
Hardbower, D.M.; Asim, M.; Luis, P.B.; Singh, K.; Barry, D.P.; Yang, C.; Steeves, M.A.; Cleveland, J.L.; Schneider, C.; Piazuelo, M.B.; Gobert, A.P.; Wilson, K.T.
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications
Proc. Natl. Acad. Sci. USA
114
E751-E760
2017
Mus musculus (P00860)
Das, M.; Kumar, R.; Dubey, V.K.
Ornithine decarboxylase of Leishmania donovani biochemical properties and possible role of N-terminal extension
Protein Pept. Lett.
22
130-136
2015
Leishmania donovani (P27116), Leishmania donovani
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