Literature summary for 4.1.1.17 extracted from

Liu, Y.C.; Hsu, D.H.; Huang, C.L.; Liu, Y.L.; Liu, G.Y.; Hung, H.C.
Determinants of the differential antizyme-binding affinity of ornithine decarboxylase (2011), PLoS ONE, 6, e26835.

Search for more literature for 4.1.1.17

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
A124R/N125D/Q129D/E136V/V137D/M140E	mutant shows very little resistance to antizyme inhibition	Homo sapiens
Q119H/A124R/N125D/E136V/V137D/M140E	mutant is moderately resistant to antizyme inhibition	Homo sapiens
Q119H/A124R/N125D/Q129D/E136V/M140E	mutant shows very little resistance to antizyme inhibition	Homo sapiens
Q119H/A124R/N125D/Q129D/E136V/V137D	mutant shows very little resistance to antizyme inhibition	Homo sapiens
Q119H/A124R/N125D/Q129D/E136V/V137D/M140E	mutations introduced to match the Trypanosoma brucei onithine decarboxylase protein sequence. Mutant is less sensitive to antizyme inhibition	Homo sapiens
Q119H/A124R/N125D/Q129D/V137D/M140E	mutant shows a pattern of inhibition similar to mutant Q119H/A124R/N125D/Q129D/E136V/V137D/M140E	Homo sapiens
Q119H/A124R/Q129D/E136V/V137D/M140E	mutant is moderately resistant to antizyme inhibition	Homo sapiens
Q119H/N125D/Q129D/E136V/V137D/M140E	mutant shows a pattern of inhibition similar to mutant Q119H/A124R/N125D/Q129D/E136V/V137D/M140E	Homo sapiens
Q119H/V137D	mutant is much less sensitive to antizyme inhibition than wild-type, pattern similar to mutant Q119H/A124R/N125D/Q129D/E136V/V137D/M140E	Homo sapiens
Q119H/V137D/M140E	mutant is much less sensitive to antizyme inhibition than wild-type, pattern similar to mutant Q119H/A124R/N125D/Q129D/E136V/V137D/M140E	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)