Cloned (Comment) | Organism |
---|---|
expression in transgenic mice expressing the human MYCN gene under the control of the rat tyrosine hydroxylase promoter | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of transgenic mice expressing the human MYCN gene under the control of the rat tyrosine hydroxylase promoter, targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-difluoromethylornithine | DFMO, a Odc suicide inhibitor, selective anticancer effects of DFMO on mouse and human MYCN-amplified neuroblastoma, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine | Homo sapiens | Odc is the first and rate-limiting enzyme of polyamine biosynthesis | putrescine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuroblastoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine | - |
Homo sapiens | putrescine + CO2 | - |
? | |
L-ornithine | Odc is the first and rate-limiting enzyme of polyamine biosynthesis | Homo sapiens | putrescine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ODC | - |
Homo sapiens |