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Literature summary for 4.1.1.17 extracted from

  • McCann, P.P.; Bacchi, C.J.; Hanson, W.L.; Nathan, H.C.; Hutner, S.H.; Sjoerdsma, A.
    Methods for the study of the treatment of protozoan diseases by inhibitors of ornithine decarboxylase (1983), Methods Enzymol., 94, 209-213.
    View publication on PubMed
Search for more literature for 4.1.1.17

Inhibitors

Inhibitors Comment Organism Structure
alpha-DL-difluoromethylornithine irreversibel Eimeria tenella
alpha-DL-difluoromethylornithine irreversibel Trypanosoma brucei
additional information treatment of protozoan diseases by inhibitors of ornithine decarboxylase Eimeria tenella
additional information treatment of protozoan diseases by inhibitors of ornithine decarboxylase Trypanosoma brucei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Orn Trypanosoma brucei first step in polyamine biosynthesis ?
-
 ?
L-Orn Eimeria tenella first step in polyamine biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Eimeria tenella
-
-
-
Trypanosoma brucei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Orn
-
 Trypanosoma brucei Putrescine + CO2
-
 ?
L-Orn
-
 Eimeria tenella Putrescine + CO2
-
 ?
L-Orn first step in polyamine biosynthesis Trypanosoma brucei ?
-
 ?
L-Orn first step in polyamine biosynthesis Eimeria tenella ?
-
 ?