Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.1.17 extracted from

  • Sklaviadis, T.K.; Georgatsos, J.G.; Kyriakidis, D.A.
    Purification and properties of ornithine decarboxylase from Tetrahymena pyriformis (1985), Biochim. Biophys. Acta, 831, 288-296.
    View publication on PubMed
Search for more literature for 4.1.1.17

Inhibitors

Inhibitors Comment Organism Structure
alpha-DL-difluoromethylornithine the nuclear enzyme is slightly more sensitive than the cytosolic Tetrahymena pyriformis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0047
-
 L-Orn
-
 Tetrahymena pyriformis
0.5
-
 L-Lys
-
 Tetrahymena pyriformis

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Tetrahymena pyriformis 5829
-
nucleus
-
 Tetrahymena pyriformis 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64000
-
 gel filtration Tetrahymena pyriformis

Organism

Organism UniProt Comment Textmining
Tetrahymena pyriformis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Tetrahymena pyriformis

Source Tissue

Source Tissue Comment Organism Textmining
cell culture maximal activity in the middle and late log phases of growth Tetrahymena pyriformis
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.23
-
-
 Tetrahymena pyriformis

Storage Stability

Storage Stability Organism
-20°C, unstable in absence of pyridoxal 5'-phosphate Tetrahymena pyriformis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Lys
-
 Tetrahymena pyriformis 1,5-diaminopentane + CO2
-
 ?
L-Orn
-
 Tetrahymena pyriformis Putrescine + CO2
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 64000, SDS-PAGE Tetrahymena pyriformis