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Literature summary for 4.1.1.17 extracted from

  • Bordallo, J.; Secades, L.; Bordallo, C.; Cantabrana, B.; Sanchez, M.
    Influence of gender and sex hormones on 5alpha-dihydrotestosterone elicited effect in isolated left atria of rats: role of beta-adrenoceptors and ornithine decarboxylase activity (2008), Eur. J. Pharmacol., 604, 103-110.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5alpha-dihydrotestosterone Rattus norvegicus administration of 0.1 mM to the heart elicits a significant increase in ornithine decarboxylase activity in the left atrium of control male rats, that tends to decrease in gonadectomized rats, the effect is significant for female rats. Testosterone plasma levels positively correlate with the gradient of modifications of ornithine decarboxylase activity elicited by 5alpha-dihydrotestosterone exposure ?
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?
L-ornithine Rattus norvegicus
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putrescine + CO2
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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estrogenized female rats and castrated male and female rats
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Source Tissue

Source Tissue Comment Organism Textmining
heart basal ornithine decarboxylase activity in isolated left atria shows differences in the four groups of animals studied, being higher in males than estrogenized females, and increased in both sexes by castration, though not significantly changed in females Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5alpha-dihydrotestosterone administration of 0.1 mM to the heart elicits a significant increase in ornithine decarboxylase activity in the left atrium of control male rats, that tends to decrease in gonadectomized rats, the effect is significant for female rats. Testosterone plasma levels positively correlate with the gradient of modifications of ornithine decarboxylase activity elicited by 5alpha-dihydrotestosterone exposure Rattus norvegicus ?
-
?
L-ornithine
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Rattus norvegicus putrescine + CO2
-
?

Synonyms

Synonyms Comment Organism
ODC
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Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
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assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
assay at Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
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Rattus norvegicus