Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Trypanosoma brucei |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-DL-difluoromethylornithine | irreversibel | Trypanosoma brucei | |
additional information | the enzyme is an important target for antitrypanosomal chemotherapy | Trypanosoma brucei |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.28 | - |
L-Orn | native enzyme | Trypanosoma brucei | |
0.33 | - |
L-Orn | recombinant enzyme | Trypanosoma brucei |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
2 * 45000, SDS-PAGE | Trypanosoma brucei |
90000 | - |
native enzyme, gel filtration | Trypanosoma brucei |
92000 | - |
recombinant enzyme, gel filtration | Trypanosoma brucei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Trypanosoma brucei |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
trypomastigote | - |
Trypanosoma brucei | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Trypanosoma brucei |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Orn | - |
Trypanosoma brucei | Putrescine + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 45000, SDS-PAGE | Trypanosoma brucei |