3.5.2.2: dihydropyrimidinase
This is an abbreviated version!
For detailed information about dihydropyrimidinase, go to the full flat file.
Word Map on EC 3.5.2.2
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3.5.2.2
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5-fluorouracil
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thymidylate
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dihydropyridine
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colorectal
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fluoropyrimidine
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phosphorylase
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thymidine
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capecitabine
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l-type
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uracil
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nifedipine
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orotate
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resect
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blocker
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pharmacogenetic
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1,4-dihydropyridine
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tegafur
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prodrugs
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voltage-dependent
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dihydrouracil
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5-fu-based
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fluoropyrimidine-based
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nitrendipine
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leucovorin
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phosphoribosyltransferase
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diltiazem
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oxaliplatin
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irinotecan
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hemoperfusion
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phosphoribosyl
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5-fluorouracil-based
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mucositis
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neutropenia
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pyrrolizidine
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11-ketotestosterone
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excitation-contraction
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isradipine
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nisoldipine
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coniferyl
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5-fu-induced
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dihydropyridine-sensitive
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felodipine
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5\'-dfur
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dihydroorotase
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photochromic
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nicardipine
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synthesis
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industry
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5'-deoxy-5-fluorouridine
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pretherapeutic
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omega-conotoxin
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nutrition
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medicine
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hand-foot
- 3.5.2.2
- 5-fluorouracil
- thymidylate
-
dihydropyridine
- colorectal
-
fluoropyrimidine
- phosphorylase
- thymidine
- capecitabine
-
l-type
- uracil
- nifedipine
- orotate
-
resect
-
blocker
-
pharmacogenetic
-
1,4-dihydropyridine
-
tegafur
-
prodrugs
-
voltage-dependent
- dihydrouracil
-
5-fu-based
-
fluoropyrimidine-based
-
nitrendipine
- leucovorin
-
phosphoribosyltransferase
- diltiazem
- oxaliplatin
- irinotecan
-
hemoperfusion
-
phosphoribosyl
-
5-fluorouracil-based
- mucositis
- neutropenia
-
pyrrolizidine
- 11-ketotestosterone
-
excitation-contraction
- isradipine
- nisoldipine
-
coniferyl
-
5-fu-induced
-
dihydropyridine-sensitive
- felodipine
-
5\'-dfur
- dihydroorotase
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photochromic
- nicardipine
- synthesis
- industry
- 5'-deoxy-5-fluorouridine
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pretherapeutic
-
omega-conotoxin
- nutrition
- medicine
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hand-foot
Reaction
Synonyms
4,5-dihydropyrimidine amidohydrolase, aaHYD, bar9HYD, bpHYD, bsHYD, CRMP, D-CpHPG, D-HYD, D-hydantionase, D-hydantoin-hydrolyzing enzyme, D-hydantoinase, D-PfHYD, DHP, DHP-1, DHP-2, DHPase, dht, DHTase, dihydropyrimidase/hydantoinase, Dihydropyrimidinase, dihydropyrimidine amidohydrolase, dihydropyrimidine dehydrogenase, HDT, HYD, hydantoin peptidase, hydantoinase, hydropyrimidine hydrase, hyuH, L-Hyd, L-hydantoinase, microbial hydantoinase, P479, PA0441, PaDHPase, PYD2, PydB, pyrimidine hydrase, SmelDhp, thHYD
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Application
Application on EC 3.5.2.2 - dihydropyrimidinase
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industry
medicine
nutrition
synthesis
additional information
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production of optically pure D-amino acids that are key intermediates in the synthesis of commercial products such as beta-lactam semisynthetic antibiotics, peptides, hormones, pyretroids and pesticides
industry
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production of optically pure D-amino acids that are key intermediates in the synthesis of commercial products such as beta-lactam semisynthetic antibiotics, peptides, hormones, pyretroids and pesticides
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medicine
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D-amino acids for preparation of beta-lactam antibiotics like semisynthetic penicillins and cephalosporins such as ampicillin, amoxicillin and cefadroxyl, peptide hormones and pesticides
medicine
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D-amino acids for preparation of beta-lactam antibiotics like semisynthetic penicillins and cephalosporins such as ampicillin, amoxicillin and cefadroxyl, peptide hormones and pesticides
medicine
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D-amino acids for preparation of beta-lactam antibiotics like semisynthetic penicillins and cephalosporins such as ampicillin, amoxicillin and cefadroxyl, peptide hormones and pesticides
medicine
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development of the enzymatic process for production of D-p-hydroxyphenylglycine from DL-5-hydroxyphenylhydantoin, new drugs based on p-hydroxyphenylglycine like aspoxicillin, cefbuperazine and cepyramide expected to be marketed in near future
medicine
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D-amino acids for preparation of beta-lactam antibiotics like semisynthetic penicillins and cephalosporins such as ampicillin, amoxicillin and cefadroxyl, peptide hormones and pesticides
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medicine
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development of the enzymatic process for production of D-p-hydroxyphenylglycine from DL-5-hydroxyphenylhydantoin, new drugs based on p-hydroxyphenylglycine like aspoxicillin, cefbuperazine and cepyramide expected to be marketed in near future
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medicine
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D-amino acids for preparation of beta-lactam antibiotics like semisynthetic penicillins and cephalosporins such as ampicillin, amoxicillin and cefadroxyl, peptide hormones and pesticides
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medicine
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development of the enzymatic process for production of D-p-hydroxyphenylglycine from DL-5-hydroxyphenylhydantoin, new drugs based on p-hydroxyphenylglycine like aspoxicillin, cefbuperazine and cepyramide expected to be marketed in near future
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nutrition
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useful for production of D-amino acids, microbial hydantoinases used industrially to produce N-carbamoyl-D-hydroxyphenylglycine
nutrition
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useful for production of D-amino acids, microbial hydantoinases used industrially to produce N-carbamoyl-D-hydroxyphenylglycine
nutrition
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no degradative activity for L-tryptophan, method for L-tryptophan production is very promising as a commercial process
synthesis
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artificial fusion enzyme useful as potential biocatalyst for production of nonnatural amino acids
synthesis
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artificial fusion enzyme useful as potential biocatalyst for production of nonnatural amino acids
synthesis
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artificial fusion enzyme useful as potential biocatalyst for production of nonnatural amino acids
synthesis
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artificial fusion enzyme useful as potential biocatalyst for production of nonnatural amino acids
synthesis
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production of enantiomeric pure nonproteinogenic amino acids, currently under investigation in bioprocess scale for industrial application
synthesis
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production of enantiomeric pure nonproteinogenic amino acids, currently under investigation in bioprocess scale for industrial application
synthesis
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used technically in combination with carbamoylases for production of D-amino acids and non-proteinogenic L-amino acids
synthesis
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commercial production of optically pure amino acids for synthesis of antibiotics, pharmaceuticals, artificial sweeteners and biologically active peptides, food ingredients, pyrethroids, pesticides, antimicrobial and antiviral agents and other agrochemicals
synthesis
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commercial production of optically pure amino acids for synthesis of antibiotics, pharmaceuticals, artificial sweeteners and biologically active peptides, food ingredients, pyrethroids, pesticides, antimicrobial and antiviral agents and other agrochemicals
synthesis
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commercial production of optically pure amino acids for synthesis of antibiotics, pharmaceuticals, artificial sweeteners and biologically active peptides, food ingredients, pyrethroids, pesticides, antimicrobial and antiviral agents and other agrochemicals
synthesis
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commercial production of optically pure amino acids for synthesis of antibiotics, pharmaceuticals, artificial sweeteners and biologically active peptides, food ingredients, pyrethroids, pesticides, antimicrobial and antiviral agents and other agrochemicals
synthesis
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thermostable enzyme with great biotechnological potential
synthesis
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industrial enzyme, that is widely used in the production of D-amino acids which are precursors for semisynthesis of antibiotics, peptides, and pesticides
synthesis
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encapsulation of a crude cell extract from Agrobacterium radiobacter containing D-hydantoinase and D-carbamoylase activities into alginate-chitosan polyelectrolyte complexes with negligible leakage from the formed capsules. The most suitable biocatalysts are prepared using a chitosan with a medium molecular weight of 600 kDa and a degree of deacetylation of 0.9. For all of the preparation conditions under study, an encapsulation yield of around 60% was achieved and the enzymatic activity yields ranged from 30 to 80% for D-hydantoinase activity and from 40 to 128% for D-carbamoylase activity relative to the activities of the soluble extract. All of the biocatalysts are able to hydrolyze LD-hydroxyphenylhydantoin into p-hydroxyphenylglycine with yields ranging from 30 to 80%
synthesis
to produce optically pure D-amino acids, microbial D-hydantoinase is used for stereospecific hydrolysis of chemically synthesized cyclic hydantoins
synthesis
the D-hydantoinase is an important enzyme capable of a reversible enantioselective ring-opening hydrolysis of hydantoins being applied for the efficient production of D-form amino acids which are key compounds applicable for the production of antibiotics, peptide hormones, pyrethroids, and pesticides in industry
synthesis
recombinant D-PfHYD can potentially be applied in the synthesis of D-amino acids
synthesis
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the D-hydantoinase is an important enzyme capable of a reversible enantioselective ring-opening hydrolysis of hydantoins being applied for the efficient production of D-form amino acids which are key compounds applicable for the production of antibiotics, peptide hormones, pyrethroids, and pesticides in industry
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synthesis
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artificial fusion enzyme useful as potential biocatalyst for production of nonnatural amino acids
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synthesis
Pseudomonas fluorescens CGMCC 1.1802
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recombinant D-PfHYD can potentially be applied in the synthesis of D-amino acids
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synthesis
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to produce optically pure D-amino acids, microbial D-hydantoinase is used for stereospecific hydrolysis of chemically synthesized cyclic hydantoins
-
synthesis
-
commercial production of optically pure amino acids for synthesis of antibiotics, pharmaceuticals, artificial sweeteners and biologically active peptides, food ingredients, pyrethroids, pesticides, antimicrobial and antiviral agents and other agrochemicals
-
synthesis
-
artificial fusion enzyme useful as potential biocatalyst for production of nonnatural amino acids
-
synthesis
-
commercial production of optically pure amino acids for synthesis of antibiotics, pharmaceuticals, artificial sweeteners and biologically active peptides, food ingredients, pyrethroids, pesticides, antimicrobial and antiviral agents and other agrochemicals
-
synthesis
-
commercial production of optically pure amino acids for synthesis of antibiotics, pharmaceuticals, artificial sweeteners and biologically active peptides, food ingredients, pyrethroids, pesticides, antimicrobial and antiviral agents and other agrochemicals
-
synthesis
-
commercial production of optically pure amino acids for synthesis of antibiotics, pharmaceuticals, artificial sweeteners and biologically active peptides, food ingredients, pyrethroids, pesticides, antimicrobial and antiviral agents and other agrochemicals
-
synthesis
-
thermostable enzyme with great biotechnological potential
-
synthesis
-
artificial fusion enzyme useful as potential biocatalyst for production of nonnatural amino acids
-
useful for industrial production of enantiomerically pure D-amino acids
additional information
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useful for industrial production of enantiomerically pure D-amino acids
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