Information on EC 3.5.2.2 - dihydropyrimidinase

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

EC NUMBER
COMMENTARY
3.5.2.2
-
RECOMMENDED NAME
GeneOntology No.
dihydropyrimidinase
-
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
5,6-dihydrouracil + H2O = 3-ureidopropanoate
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
carboxylic acid amide hydrolysis
-
-
-
-
carboxylic acid amide hydrolysis
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
thymine degradation
-
-
uracil degradation I (reductive)
-
-
alanine metabolism
-
-
pyrimidine metabolism
-
-
Pyrimidine metabolism
-
-
beta-Alanine metabolism
-
-
Pantothenate and CoA biosynthesis
-
-
Drug metabolism - other enzymes
-
-
Metabolic pathways
-
-
SYSTEMATIC NAME
IUBMB Comments
5,6-dihydropyrimidine amidohydrolase
Also acts on dihydrothymine and hydantoin.
SYNONYMS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
4,5-dihydropyrimidine amidohydrolase
-
-
4,5-dihydropyrimidine amidohydrolase
Rattus norvegicus Sprague-Dawley
-
-
-
bar9HYD
-
-
bar9HYD
-
-
-
CRMP
Drosophila melanogaster EP(3)3238
-
-
D-hydantionase
-
-
D-hydantionase
Agrobacterium tumefaciens NRRL
-
-
-
D-hydantoinase
-
-
-
-
D-hydantoinase
Agrobacterium tumefaciens BQL9, Agrobacterium tumefaciens DUL-DH101
-
-
-
D-hydantoinase
Arthrobacter crystallopoietes DSM20117
-
-
D-hydantoinase
-
-
D-hydantoinase
-
-
-
D-hydantoinase
-
-
D-hydantoinase
Burkholderia cepacia JS-02, Burkholderia cepacia njut01
-
-
-
D-hydantoinase
Geobacillus stearothermophilus SD1
-
-
D-hydantoinase
-
D-hydantoinase
Pseudomonas putida 7711-2
-
-
-
D-hydantoinase
Pseudomonas putida CCRC
-
-
D-hydantoinase
Pseudomonas putida YZ-26
-
-
D-hydantoinase
-
D-hydantoinase
-
-
DHP
-
-
-
-
DHP
Drosophila melanogaster EP(3)3238
-
-
DHP
Pseudomonas putida RU-KM3S
-
-
DHP
Pseudomonas putida YZ-26
-
-
-
DHP
Salmonella enterica subsp. enterica serovar Typhimurium LT2
-
-
DHPase
-
-
Dihydropyrimidinase
-
-
-
-
Dihydropyrimidinase
-
Dihydropyrimidinase
Pseudomonas putida RU-KM3S
-
-
dihydropyrimidine amidohydrolase
-
-
dihydropyrimidine amidohydrolase
-
-
dihydropyrimidine amidohydrolase
-
-
dihydropyrimidine amidohydrolase
-
-
dihydropyrimidine amidohydrolase
-
-
dihydropyrimidine dehydrogenase
-
-
HDT
Agrobacterium tumefaciens NRRL
-
-
-
HYD
Pseudomonas putida YZ-26
-
-
hydantoin peptidase
-
-
-
-
hydantoinase
-
-
-
-
hydantoinase
-
-
hydantoinase
Agrobacterium tumefaciens NRRL B11291
-
-
-
hydantoinase
-
-
hydantoinase
Arthrobacter crystallopoietes DSM20117
-
-
hydantoinase
-
-
hydantoinase
Ensifer adhaerens S-5
-
-
-
hydantoinase
Microbacterium liquefaciens AJ3912
-
-
-
hydantoinase
-
-
hydantoinase
-
-
hydantoinase
Pseudomonas putida RU-KM3
-
-
-
hydantoinase
Pseudomonas putida RU-KM3S
-
-
hydantoinase
Pseudomonas putida RUKM3s
-
-
-
hydantoinase
-
-
hydantoinase
-
-
hydantoinase
-
-
hydantoinase
-
hydropyrimidine hydrase
-
-
-
-
hyuH
Arthrobacter crystallopoietes DSM20117
-
-
hyuH
Microbacterium liquefaciens AJ3912
-
-
-
L-hydantoinase
-
-
microbial hydantoinase
-
-
P479
Pseudomonas putida YZ-26
-
-
-
PydB
Brevibacillus agri NCHU1002
-
-
-
pyrimidine hydrase
-
-
-
-
SmelDhp
possesses both hydantoinase and dihydropyrimidinase activities
SmelDhp
Sinorhizobium meliloti CECT4114
possesses both hydantoinase and dihydropyrimidinase activities
-
thHYD
-
-
CAS REGISTRY NUMBER
COMMENTARY
9030-74-4
-
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain 30148, 30199, 30200
-
-
Manually annotated by BRENDA team
Agrobacterium rhizogenes 30148
strain 30148, 30199, 30200
-
-
Manually annotated by BRENDA team
strain 30149, 30155
-
-
Manually annotated by BRENDA team
Agrobacterium rubi 30149
strain 30149, 30155
-
-
Manually annotated by BRENDA team
strain 30201, 30203
-
-
Manually annotated by BRENDA team
Agrobacterium sp. 30201
strain 30201, 30203
-
-
Manually annotated by BRENDA team
Agrobacterium sp. IP-I 671
strain IP-I 671
-
-
Manually annotated by BRENDA team
; strain CIP 67.1
-
-
Manually annotated by BRENDA team
strain 30147, 30199, NRRL B-11291
-
-
Manually annotated by BRENDA team
strain 30147, 30199, NRRL B-11291; strain 30150, 30205, 30206, 30207
-
-
Manually annotated by BRENDA team
strain NRRL B 11291
-
-
Manually annotated by BRENDA team
strain NRRL B11291
-
-
Manually annotated by BRENDA team
strain RU-AE01
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens 30147
strain 30147, 30199, NRRL B-11291
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens 30150
strain 30150, 30205, 30206, 30207
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens 47C
strain 47C
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens BQL9
BQL9
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens BQL9
strain BQL9
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens CIP 67.1
strain CIP 67.1
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens DUL-DH101
DUL-DH101
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens NRRL
strain NRRL B 11291
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens NRRL
strain NRRL B11291
-
-
Manually annotated by BRENDA team
Agrobacterium tumefaciens NRRL B11291
NRRL B11291
-
-
Manually annotated by BRENDA team
strain DSM20117
SwissProt
Manually annotated by BRENDA team
Arthrobacter crystallopoietes DSM20117
-
-
-
Manually annotated by BRENDA team
Arthrobacter crystallopoietes DSM20117
strain DSM20117
SwissProt
Manually annotated by BRENDA team
Arthrobacter sp. DSM3747
DSM3747
-
-
Manually annotated by BRENDA team
strain MH602
UniProt
Manually annotated by BRENDA team
LU 1220
-
-
Manually annotated by BRENDA team
strain AR9
-
-
Manually annotated by BRENDA team
TS-23
SwissProt
Manually annotated by BRENDA team
strain AR9
-
-
Manually annotated by BRENDA team
Bacillus sp. LU 1220
LU 1220
-
-
Manually annotated by BRENDA team
TS-23
SwissProt
Manually annotated by BRENDA team
beef
-
-
Manually annotated by BRENDA team
beef; calf
-
-
Manually annotated by BRENDA team
bovine; calf
-
-
Manually annotated by BRENDA team
calf; ox
-
-
Manually annotated by BRENDA team
strain NCHU1002
-
-
Manually annotated by BRENDA team
Brevibacillus agri NCHU1002
strain NCHU1002
-
-
Manually annotated by BRENDA team
L-specific hydantoinase
-
-
Manually annotated by BRENDA team
strain JS-02
-
-
Manually annotated by BRENDA team
strain njut01
-
-
Manually annotated by BRENDA team
Burkholderia cepacia JS-02
strain JS-02
-
-
Manually annotated by BRENDA team
Burkholderia cepacia njut01
strain njut01
-
-
Manually annotated by BRENDA team
guinea-pig
-
-
Manually annotated by BRENDA team
pigeon
-
-
Manually annotated by BRENDA team
Corynebacterium pseudodiphtheriticum 14.10
strain 14.10
-
-
Manually annotated by BRENDA team
Delftia sp. I24 DSM18833
-
-
-
Manually annotated by BRENDA team
mutant supA4; strain EP(3)3238 CRMPsup mutants
SwissProt
Manually annotated by BRENDA team
strain EP(3)3238 CRMPsup mutants
SwissProt
Manually annotated by BRENDA team
Drosophila melanogaster EP(3)3238
mutant supA4; strain EP(3)3238 CRMPsup mutants
SwissProt
Manually annotated by BRENDA team
Drosophila melanogaster EP(3)3238
strain EP(3)3238 CRMPsup mutants
SwissProt
Manually annotated by BRENDA team
strain S-5
-
-
Manually annotated by BRENDA team
Ensifer adhaerens S-5
strain S-5
-
-
Manually annotated by BRENDA team
I-3, FERM-P no. 6901, facultively anaerobic, non-spore forming, gram-negative, motile with peritrichous flagella
-
-
Manually annotated by BRENDA team
Flavobacterium sp. AJ-3912
AJ-3912
-
-
Manually annotated by BRENDA team
i.e. Bacillus stearothermophilus
SwissProt
Manually annotated by BRENDA team
strain SD-1; strains NS1122A and LU1220
-
-
Manually annotated by BRENDA team
strains NS1122A and LU1220
-
-
Manually annotated by BRENDA team
Geobacillus stearothermophilus JC2310
strain JC2310
-
-
Manually annotated by BRENDA team
Geobacillus stearothermophilus SD-1
strain SD-1
-
-
Manually annotated by BRENDA team
Geobacillus stearothermophilus SD1
i.e. Bacillus stearothermophilus
SwissProt
Manually annotated by BRENDA team
Geobacillus stearothermophilus SD1
SD1
-
-
Manually annotated by BRENDA team
Geobacillus thermocatenulatus GH-2
strain GH-2
-
-
Manually annotated by BRENDA team
Microbacterium liquefaciens AJ3912
AJ3912
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
no activity in Agrobacterium tumefaciens
-
-
-
Manually annotated by BRENDA team
no activity in Agrobacterium tumefaciens 30204
-
-
-
Manually annotated by BRENDA team
no activity in Bacillus alcalophilus
-
-
-
Manually annotated by BRENDA team
no activity in Pseudomonas putida
-
-
-
Manually annotated by BRENDA team
no activity in Pseudomonas putida DSM 1693
-
-
-
Manually annotated by BRENDA team
no activity in Pseudomonas putida DSM 549
-
-
-
Manually annotated by BRENDA team
Ochrobactrum sp. G21 DSM18828
-
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
Peptococcus anaerobius
-
-
-
Manually annotated by BRENDA team
strains 1.2 and 1.9
-
-
Manually annotated by BRENDA team
; DSM 84, formerly classified as P. fluorescens; strains 2.2, 2.5
-
-
Manually annotated by BRENDA team
; strain 77
-
-
Manually annotated by BRENDA team
biotype B, strain ATCC 17536
-
-
Manually annotated by BRENDA team
DSM 84, formerly classified as P. fluorescens
-
-
Manually annotated by BRENDA team
formerly classified as P. striata
-
-
Manually annotated by BRENDA team
strain 7711-2
-
-
Manually annotated by BRENDA team
strain CCRC 12857
SwissProt
Manually annotated by BRENDA team
strain RU-KM3
-
-
Manually annotated by BRENDA team
strain RU-KM3S
SwissProt
Manually annotated by BRENDA team
strain RUKM3s
-
-
Manually annotated by BRENDA team
strain YZ-26
SwissProt
Manually annotated by BRENDA team
strain YZ-26
-
-
Manually annotated by BRENDA team
YZ-26
SwissProt
Manually annotated by BRENDA team
Pseudomonas putida 7711-2
strain 7711-2
-
-
Manually annotated by BRENDA team
Pseudomonas putida CCRC
strain CCRC 12857
SwissProt
Manually annotated by BRENDA team
Pseudomonas putida RU-KM3
strain RU-KM3
-
-
Manually annotated by BRENDA team
Pseudomonas putida RU-KM3S
strain RU-KM3S
SwissProt
Manually annotated by BRENDA team
Pseudomonas putida RUKM3s
strain RUKM3s
-
-
Manually annotated by BRENDA team
Pseudomonas putida YZ-26
strain YZ-26
SwissProt
Manually annotated by BRENDA team
Pseudomonas putida YZ-26
strain YZ-26
-
-
Manually annotated by BRENDA team
Pseudomonas putida YZ-26
YZ-26
SwissProt
Manually annotated by BRENDA team
strain AJ-11220
-
-
Manually annotated by BRENDA team
strain NS671
-
-
Manually annotated by BRENDA team
Pseudomonas sp. AJ-11220
strain AJ-11220
-
-
Manually annotated by BRENDA team
rat; strain Sprague-Dawley
-
-
Manually annotated by BRENDA team
Rattus norvegicus Sprague-Dawley
strain Sprague-Dawley
-
-
Manually annotated by BRENDA team
Salmonella enterica subsp. enterica serovar Typhimurium LT2
LT2
UniProt
Manually annotated by BRENDA team
strain 1.15
-
-
Manually annotated by BRENDA team
Serratia liquefaciens 1.15
strain 1.15
-
-
Manually annotated by BRENDA team
strain CECT4114
UniProt
Manually annotated by BRENDA team
strain CECT4114
-
-
Manually annotated by BRENDA team
Sinorhizobium meliloti CECT4114
strain CECT4114
UniProt
Manually annotated by BRENDA team
Streptomyces mitakaensis
-
-
-
Manually annotated by BRENDA team
pig
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
thermophilic bacterial strains, CBS 303.80 and CBS363.80, asporogenic gram-negative
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
physiological function
hydantoinase and L-carbamoylase are involved in the conversion of DL-5-substituted hydantoins to an N-carbamyl intermediate that is subsequently converted to L-alpha-amino acids
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-methylhydantoin + H2O
3-methylhydantoic acid
show the reaction diagram
-
-
-
?
1-methylhydantoin + H2O
3-methylhydantoic acid
show the reaction diagram
-
poor substrate
-
?
2-imidazolidone + H2O
?
show the reaction diagram
-
-
-
-
?
2-thiohydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
2-thiouracil + H2O
?
show the reaction diagram
Agrobacterium sp., Agrobacterium sp. IP-I 671
-
-
-
-
?
3-ethylphenylhydantoin + H2O
2-phenylhydantoic acid
show the reaction diagram
-
-
-
?
3-methylphenylhydantoin + H2O
2-phenylhydantoic acid
show the reaction diagram
-
-
-
?
3-phenylhydantoin + H2O
2-phenylhydantoic acid
show the reaction diagram
-
-
-
?
5,5-dimethylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
?
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
?
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
-
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
-
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
r
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
-
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
r
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
-
-
5,6-dihydrothymine + H2O
?
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
Sinorhizobium meliloti CECT4114
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
Bacillus sp. LU 1220
-
-
-
-
?
5,6-dihydrothymine + H2O
3-(carbamoylamino)-2-methylpropanoic acid
show the reaction diagram
-
-
-
?
5,6-dihydrothymine + H2O
N-carbamyl-beta-aminoisobutyrate
show the reaction diagram
-
-
-
r
5,6-dihydrothymine + H2O
N-carbamyl-beta-aminoisobutyrate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Peptococcus anaerobius
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
purified preparation demonstrates no activity on this substrate
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium rubi 30149
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium rubi 30149
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium sp. IP-I 671
-
purified preparation demonstrates no activity on this substrate
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Serratia liquefaciens 1.15
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens CIP 67.1
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium rhizogenes 30148
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium rhizogenes 30148
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Sinorhizobium meliloti CECT4114
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Geobacillus stearothermophilus JC2310
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Corynebacterium pseudodiphtheriticum 14.10
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 47C
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Geobacillus thermocatenulatus GH-2
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Bacillus sp. LU 1220
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium sp. 1-671
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Flavobacterium sp. AJ-3912, Geobacillus stearothermophilus NS1122A
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropanoate
show the reaction diagram
-
26% relative enzyme activity
-
?
5,6-dihydrouracil + H2O
?
show the reaction diagram
2.35fold elevated hydantoinase activity in uninduced mutant cells compared with the wild type, but equivalent enzyme activity in induced mutant and wild type cells
-
-
?
5,6-dihydrouracil + H2O
?
show the reaction diagram
highest activity of the EDTA-dialyzed/Co2+-substituted enzyme
-
-
?
5,6-dihydrouracil + H2O
?
show the reaction diagram
Pseudomonas putida RU-KM3S
2.35fold elevated hydantoinase activity in uninduced mutant cells compared with the wild type, but equivalent enzyme activity in induced mutant and wild type cells
-
-
?
5,6-dihydrouracil + H2O
N-carbamoyl-beta-alanine
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
N-carbamoyl-beta-alanine
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
N-carbamoyl-beta-alanine
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
N-carbamoyl-beta-alanine
show the reaction diagram
Pseudomonas putida, Pseudomonas putida YZ-26
-
-
-
?
5,6-dihydrouracil + H2O
N-carbamyl-beta-alanine
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
N-carbamyl-beta-alanine
show the reaction diagram
-
-
-
?
5-(2-thienyl)-DL-hydantoin + H2O
N-carbamoyl-D-2-thienylglycine
show the reaction diagram
-
-
-
?
5-(2-thienyl)-DL-hydantoin + H2O
N-carbamoyl-D-2-thienylglycine
show the reaction diagram
-
-
-
?
5-(4-hydroxyphenyl)hydantoin + H2O
5-(4-hydroxyphenyl)-D-carbamoylate
show the reaction diagram
-
-
-
?
5-(p-hydroxybenzyl)hydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
5-(p-hydroxybenzyl)hydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
5-bromo-5,6-dihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
?
5-bromo-5,6-dihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
r
5-bromo-5,6-dihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
-
5-bromo-5,6-dihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
r
5-fluoro-5,6-dihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
-
5-fluoro-5,6-dihydrouracil + H2O
?
show the reaction diagram
-
less effective substrate
-
-
?
5-fluorouracil + H2O
2-fluoro-3-ureidopropionic acid
show the reaction diagram
Pseudomonas putida, Pseudomonas putida RU-KM3S
growth of GMP1 and GMP2 mutants but not of wild-type RU-KM3S, mutants independent of inducer
-
?
5-fluorouracil + hydantoin
2-fluoro-3-ureidopropionic acid + ?
show the reaction diagram
Pseudomonas putida, Pseudomonas putida RU-KM3S
growth of GMP1 and GMP2 mutants and wild-type RU-KM3S
-
?
5-hydroxymethylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
5-iodo-5,6-dihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
?
5-leucinyl-hydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens NRRL B11291
-
-
-
-
?
5-phenylhydantoin + H2O
5-phenyl D-carbamoylate
show the reaction diagram
-
-
-
?
5-phenylhydantoin + H2O
D-phenylglycine + CO2 + NH3
show the reaction diagram
-
-
-
?
6-azauracil + H2O
?
show the reaction diagram
Agrobacterium sp., Agrobacterium sp. IP-I 671
-
-
-
-
?
allantoin + H2O
?
show the reaction diagram
-
-
-
-
?
allantoin + H2O
?
show the reaction diagram
-
-
-
-
?
allantoin + H2O
?
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
-
?
alpha-phenylsuccinimide + H2O
2-phenylsuccinamic acid
show the reaction diagram
-
-
-
?
beta-ureidoisobutyrate
dihydrothymine + H2O
show the reaction diagram
-
-
-
r
carbamoyl beta-aminoisobutyric acid + H2O
?
show the reaction diagram
-
-
-
-
?
carbamoyl beta-aminoisobutyric acid + H2O
?
show the reaction diagram
-
-
-
-
?
D,L-benzylhydantoin + H2O
?
show the reaction diagram
Burkholderia cepacia, Burkholderia cepacia JS-02
-
-
-
-
?
D-2-phenylhydantoic acid + H2O
5-phenylhydantoin
show the reaction diagram
-
reverse reaction stereospecific, only D-isomer acts as substrate
-
r
D-5(p-hydroxybenzyl)-hydantoin + H2O
N-carbamoyl-D-tyrosine
show the reaction diagram
-
-
-
-
D-5-(1-methylpropyl)hydantoin + H2O
N-carbamoyl-D-isoleucine
show the reaction diagram
-
-
-
?
D-5-(2-methylthioethyl)hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
-
D-5-(2-methylthioethyl)hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
D-5-(2-methylthioethyl)hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
-
D-5-benzylhydantoin + H2O
N-carbamoyl-D-phenylalanine
show the reaction diagram
-
-
-
?
D-5-benzylhydantoin + H2O
N-carbamoyl-D-phenylalanine
show the reaction diagram
-
-
-
?
D-5-butylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
D-5-ethylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
D-5-ethylhydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens BQL9
-
-
-
-
r
D-5-isobutylhydantoin + H2O
N-carbamoyl-D-leucine
show the reaction diagram
Geobacillus stearothermophilus, Geobacillus stearothermophilus NS1122A
-
-
-
?
D-5-isobutylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
D-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Geobacillus stearothermophilus, Geobacillus stearothermophilus NS1122A
-
-
-
?
D-5-isopropylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
D-5-methyl-thio-ethylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
D-5-methylhydantoin + H2O
N-carbamoyl-D-alanine
show the reaction diagram
-
-
-
?
D-5-methylhydantoin + H2O
N-carbamoyl-D-alanine
show the reaction diagram
-
-
-
?
D-5-methylhydantoin + H2O
N-carbamoyl-D-alanine
show the reaction diagram
-
-
-
?
D-5-methylhydantoin + H2O
N-carbamoyl-D-alanine
show the reaction diagram
-
-
-
?
D-5-methylhydantoin + H2O
N-carbamoyl-D-alanine
show the reaction diagram
-
L-5-methylhydantoin is no substrate
-
?
D-5-methylhydantoin + H2O
N-carbamoyl-D-alanine
show the reaction diagram
Geobacillus stearothermophilus NS1122A
-
-
-
?
D-5-methylthioethylhydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens BQL9
-
-
-
-
r
D-5-propylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
D-benzylhydantoin
D-N-carbamoylphenylalanine
show the reaction diagram
Microbacterium liquefaciens, Microbacterium liquefaciens AJ3912
-
-
-
?
D-benzylhydantoin + H2O
D-N-carbamoylphenylalanine
show the reaction diagram
-
-
?
D-methylhydantoin + H2O
?
show the reaction diagram
Pseudomonas putida, Pseudomonas putida RU-KM3S
1.57fold elevated hydantoinase activity in uninduced mutant cells compared with the wild type, but equivalent enzyme activity in induced mutant and wild type cells
-
-
?
dihydroorotic acid + H2O
?
show the reaction diagram
-
-
-
-
?
dihydropyrimidine + H2O
N-carbamoyl amino acid
show the reaction diagram
-
-
-
r
dihydropyrimidine + H2O
N-carbamoyl amino acid
show the reaction diagram
-
-
-
r
dihydropyrimidine + H2O
N-carbamoyl amino acid
show the reaction diagram
-
-
-
r
dihydropyrimidine + H2O
N-carbamoyl amino acid
show the reaction diagram
-
-
-
r
dihydropyrimidine + H2O
N-carbamoyl amino acid
show the reaction diagram
-
-
-
?
dihydropyrimidine + H2O
N-carbamoyl amino acid
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
r
dihydrothymidine + H2O
?
show the reaction diagram
-
-
-
-
?
dihydrothymine + H2O
N-carbamoyl-beta-aminoisobutyric acid
show the reaction diagram
-
-
-
?
dihydrouracil + H2O
N-carbamoyl-beta-alanine
show the reaction diagram
-
-
-
?
dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens NRRL B11291
-
-
-
?
dihydrouracil + H2O
ureidopropionate
show the reaction diagram
-
-
-
?
dihydrouracil + H2O
ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens BQL9
-
-
-
?
dimethylhydantoin + H2O
?
show the reaction diagram
1.4% of the activity with dihydrouracil
-
-
?
DL-5(2-(methylthio)-ethyl)hydantoin + H2O
?
show the reaction diagram
EDTA-dialyzed/Co2+-substituted enzyme
-
-
?
DL-5-(2-carboxyethyl)hydantoin + H2O
L-glutamic acid
show the reaction diagram
-
-
exclusively L-form
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
-
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
-
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
-
steric configuration D
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
strictly D-selective
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
-
the enzyme exhibits strict D-enantioselectivity for DL-5-(2-methylthioethyl)-hydantoin
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Brevibacillus agri NCHU1002
-
the enzyme exhibits strict D-enantioselectivity for DL-5-(2-methylthioethyl)-hydantoin
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium tumefaciens CIP 67.1
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Bacillus sp. LU 1220
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
DL-5-(2-methylthioethyl)-hydantoin + H2O
N-carbamoyl-D-methionine
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
-
produces stereospecifically D-p-hydroxyphenylglycine
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Pseudomonas putida 7711-2
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Pseudomonas putida CCRC
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Geobacillus thermocatenulatus GH-2
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Bacillus sp. LU 1220
-
-
-
?
DL-5-(p-hydroxyphenyl)hydantoin + H2O
N-carbamoyl-p-hydroxyphenylglycine
show the reaction diagram
Agrobacterium sp. 1-671
-
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
poorly hydrolyzed
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
-
only slight activity
-
-
?
DL-5-benzylhydantoin + H2O
?
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
-
?
DL-5-butylhydantoin
?
show the reaction diagram
-
-
-
-
?
DL-5-carboxyethylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-cyanoethylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-indolylmethylhydantoin + H2O
L-tryptophan
show the reaction diagram
-
-
-
?
DL-5-indolylmethylhydantoin + H2O
L-tryptophan
show the reaction diagram
-
-
-
?
DL-5-indolylmethylhydantoin + H2O
L-tryptophan
show the reaction diagram
-
-
-
?
DL-5-indolylmethylhydantoin + H2O
L-tryptophan
show the reaction diagram
-
-
-
?
DL-5-indolylmethylhydantoin + H2O
L-tryptophan
show the reaction diagram
-
-
-
?
DL-5-indolylmethylhydantoin + H2O
L-tryptophan
show the reaction diagram
-
strictly L-selective for the cleavage
-
?
DL-5-indolylmethylhydantoin + H2O
L-tryptophan
show the reaction diagram
-
strictly D-selective
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens CIP 67.1
-
-
-
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens 47C
-
-
-
-
?
DL-5-isobutyl-hydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
only D-isomer hydrolyzed
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
-
only D-isomer hydrolyzed
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium tumefaciens CIP 67.1
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Sinorhizobium meliloti CECT4114
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium tumefaciens 47C
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Geobacillus thermocatenulatus GH-2
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
DL-5-isopropylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
DL-5-methyldihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-methylhydantoin
?
show the reaction diagram
-
-
-
-
-
DL-5-methylhydantoin
?
show the reaction diagram
-
-
-
-
?
DL-5-methylhydantoin
?
show the reaction diagram
-
-
-
-
?
DL-5-methylhydantoin
?
show the reaction diagram
-
-
-
-
?
DL-5-p-hydroxyphenylhydantoin + H2O
D-p-hydroxyphenylglycine
show the reaction diagram
Ensifer adhaerens, Ensifer adhaerens S-5
-
hydantoinase and carbamylase involved
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
-
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
-
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
-
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
-
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
r
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
45% of the activity with dihydrouracil
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
r
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
Geobacillus stearothermophilus JC2310
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
Geobacillus thermocatenulatus GH-2
-
-
-
?
DL-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
Pseudomonas putida YZ-26
-
-
-
?
DL-5-propylhydantoin
?
show the reaction diagram
-
-
-
-
?
DL-5-sec-butylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-sec-butylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-5-sec-butylhydantoin + H2O
?
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
-
?
DL-5-sec-butylhydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens CIP 67.1
-
-
-
-
?
DL-5-sec-butylhydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens 47C
-
-
-
-
?
DL-5-thienylmethylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-6-(4-chlorophenyl)-5,6-dihydrouracil + H2O
4-chloro-N-carbamoyl-beta-phenylalanine
show the reaction diagram
Arthrobacter crystallopoietes, Ochrobactrum sp. G21, Delftia sp. I24, Ochrobactrum sp. G21 DSM18828, Arthrobacter crystallopoietes DSM20117, Delftia sp. I24 DSM18833
-
-
-
?
DL-6-isopropyldihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
?
DL-6-methyldihydrouracil + H2O
?
show the reaction diagram
-
-
-
-
?
DL-6-phenyl-5,6-dihydrouracil + H2O
N-rac-carbamoyl-beta-phenylalanine
show the reaction diagram
-
-
27% conversion. Enzyme preferably hydrolyzes L-Phe-5,6-dihydrouracil to L-N-carbamoyl-beta-phenylalanine, 61% enantiomeric excess of L-enantiomer
?
DL-6-phenyl-5,6-dihydrouracil + H2O
N-rac-carbamoyl-beta-phenylalanine
show the reaction diagram
Ochrobactrum sp. G21, Delftia sp. I24, Ochrobactrum sp. G21 DSM18828
-
-
enzyme does not display a significant entantioselectivity
?
DL-6-phenyl-5,6-dihydrouracil + H2O
N-rac-carbamoyl-beta-phenylalanine
show the reaction diagram
Arthrobacter crystallopoietes DSM20117
-
-
27% conversion. Enzyme preferably hydrolyzes L-Phe-5,6-dihydrouracil to L-N-carbamoyl-beta-phenylalanine, 61% enantiomeric excess of L-enantiomer
?
DL-6-phenyl-5,6-dihydrouracil + H2O
N-rac-carbamoyl-beta-phenylalanine
show the reaction diagram
Delftia sp. I24 DSM18833
-
-
enzyme does not display a significant entantioselectivity
?
DL-fluorobromylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
DL-homophenylalanylhydantoin + H2O
?
show the reaction diagram
Brevibacillus agri, Brevibacillus agri NCHU1002
-
the enzyme exhibits non-enantiospecificity for DL-homophenylalanylhydantoin
-
-
?
DL-hydroxymethylhydantoin + H2O
?
show the reaction diagram
Geobacillus stearothermophilus, Geobacillus stearothermophilus SD1
-
-
-
-
?
DL-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
Geobacillus stearothermophilus SD1
-
-
-
?
DL-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
Agrobacterium tumefaciens BQL9
-
-
-
?
DL-hydroxyphenylhydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens NRRL
-
-
-
-
?
DL-isoproylhydantoin + H2O
N-carbamoyl-D-valine
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens BQL9
-
-
-
?
DL-methylthioethylhydantoin + H2O
?
show the reaction diagram
-
D-selective for the hydrolysis
-
-
?
DL-p-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-p-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
-
-
-
?
DL-p-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
-
19% relative enzyme activity
-
?
DL-p-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
Brevibacillus agri, Brevibacillus agri NCHU1002
-
the enzyme exhibits strict D-enantioselectivity for DL-p-hydroxyphenylhydantoin
-
?
DL-p-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
-
19% relative enzyme activity
-
?
DL-p-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-hydroxyphenylglycine
show the reaction diagram
Pseudomonas putida YZ-26
-
-
-
?
DL-p-hydroxyphenylhydantoin + H2O
?
show the reaction diagram
EDTA-dialyzed/Co2+-substituted enzyme
-
-
?
DL-p-hydroxyphenylhydantoin + H2O
N-carbamoyl-D-p-hydroxyphenylglycine
show the reaction diagram
7.2% of the activity with dihydrouracil
-
?
DL-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
-
-
?
DL-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
39.9% relative enzyme activity
-
?
DL-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
Geobacillus stearothermophilus SD1
-
-
-
?
DL-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
39.9% relative enzyme activity
-
?
glutarimide + H2O
?
show the reaction diagram
-
-
-
-
?
glutarimide + H2O
?
show the reaction diagram
-
-
-
-
?
glutarimide + H2O
?
show the reaction diagram
-
-
-
-
-
glutarimide + H2O
?
show the reaction diagram
-
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
-
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
-
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
-
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
r
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Peptococcus anaerobius
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
poorly hydrolyzed
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
18.7% of the activity with dihydrouracil
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Agrobacterium tumefaciens NRRL B11291
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Geobacillus stearothermophilus SD1
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Geobacillus stearothermophilus JC2310
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Agrobacterium tumefaciens BQL9
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Geobacillus thermocatenulatus GH-2
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Geobacillus thermocatenulatus GH-2
-
-
-
?
hydantoin + H2O
hydantoic acid
show the reaction diagram
Bacillus sp. LU 1220
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
r
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
ir
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
r
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Peptococcus anaerobius
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
4fold elevated hydantoinase activity in uninduced mutant cells compared with the wild type, but equivalent enzyme activity in induced mutant and wild type cells
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
preferred substrate, 100% relative enzyme activity
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Arthrobacter sp. DSM3747
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Arthrobacter sp. DSM3747
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium rubi 30149
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium rubi 30149
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Serratia liquefaciens 1.15
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Pseudomonas sp. AJ-11220
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium rhizogenes 30148
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium rhizogenes 30148
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens NRRL
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus JC2310
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Corynebacterium pseudodiphtheriticum 14.10
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
preferred substrate, 100% relative enzyme activity
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus thermocatenulatus GH-2
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium sp. 1-671
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Pseudomonas putida YZ-26
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Pseudomonas putida RU-KM3S
4fold elevated hydantoinase activity in uninduced mutant cells compared with the wild type, but equivalent enzyme activity in induced mutant and wild type cells
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Flavobacterium sp. AJ-3912
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
-
-
?
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
-
-
?
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
Pseudomonas putida RU-KM3
-
-
-
?
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
Pseudomonas putida YZ-26
-
-
-
-
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
Pseudomonas putida YZ-26
-
-
?
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
Pseudomonas putida YZ-26
-
-
-
?
hydantoin + H2O
N-carbamoylglycine
show the reaction diagram
Pseudomonas putida YZ-26
-
-
?
hydantoin + H2O
?
show the reaction diagram
lowest activity of the EDTA-dialyzed/Co2+-substituted enzyme
-
-
?
hydantoin + H2O
ureidoacetic acid
show the reaction diagram
-
-
-
?
hydrothymine
carbamoyl beta-aminoisobutyric acid
show the reaction diagram
-
-
-
?
hydrouracil + H2O
N-carbamoyl beta-alanine
show the reaction diagram
-
-
-
?
L-5-(1-methylpropyl)hydantoin + H2O
N-carbamoyl-L-isoleucine
show the reaction diagram
-
-
-
?
L-5-(2-methylthioethyl)hydantoin + H2O
N-carbamoyl-L-methionine
show the reaction diagram
-
-
-
?
L-5-(2-methylthioethyl)hydantoin + H2O
N-carbamoyl-L-methionine
show the reaction diagram
-
-
-
?
L-5-benzylhydantoin + H2O
N-carbamoyl-L-phenylalanine
show the reaction diagram
-
-
-
?
L-5-ethylhydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens BQL9
-
-
-
-
r
L-5-isobutylhydantoin + H2O
N-carbamoyl-L-leucine
show the reaction diagram
Geobacillus stearothermophilus, Geobacillus stearothermophilus NS1122A
-
-
-
?
L-5-methylhydantoin + H2O
N-carbamoyl-L-alanine
show the reaction diagram
-
-
-
?
L-5-methylthioethylhydantoin + H2O
?
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens BQL9
-
-
-
-
r
L-benzylhydantoin
L-N-carbamoylphenylalanine
show the reaction diagram
Microbacterium liquefaciens, Microbacterium liquefaciens AJ3912
-
-
-
?
m-chlorophenylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
m-chlorophenylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
N-carbamoyl beta-alanine + H2O
5,6-dihydrouracil
show the reaction diagram
-
-
-
r
N-carbamoyl beta-alanine + H2O
5,6-dihydrouracil
show the reaction diagram
-
-
-
r
N-carbamoyl beta-alanine + H2O
5,6-dihydrouracil
show the reaction diagram
-
-
-
r
N-carbamoyl beta-alanine + H2O
5,6-dihydrouracil
show the reaction diagram
-
-
-
r
N-carbamoyl beta-alanine + H2O
5,6-dihydrouracil
show the reaction diagram
-
-
-
r
N-carbamoyl beta-alanine + H2O
5,6-dihydrouracil
show the reaction diagram
-
-
-
r
N-carbamoyl beta-alanine + H2O
5,6-dihydrouracil
show the reaction diagram
-
-
-
r
N-carbamoyl-beta-alanine + H2O
?
show the reaction diagram
-
-
-
-
?
N-carbamoyl-L-tryptophan + H2O
L-tryptophan + ?
show the reaction diagram
-
N-carbamoyl-D-tryptophan is no substrate
-
?
p-chlorophenylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
p-chlorophenylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
p-chlorophenylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
p-methoxyphenylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
p-methylphenylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
phthalimide + H2O
?
show the reaction diagram
Agrobacterium tumefaciens, Agrobacterium tumefaciens NRRL B11291
-
low activity
-
-
?
rac-5-p-fluorophenylhydantoin + H2O
?
show the reaction diagram
-
immobilized enzyme (linked to aminopropyl glass beads) converts 100%
-
-
?
rac-5-p-trifluoromethylphenylhydantoin + H2O
?
show the reaction diagram
-
immobilized enzyme (linked to aminopropyl glass beads) converts 87%
-
-
?
rac-5-phenylhydantoin + H2O
N-carbamoyl-D-phenylglycine
show the reaction diagram
-
immobilized enzyme (linked to aminopropyl glass beads) converts 100%
-
?
succinimide + H2O
?
show the reaction diagram
-
-
-
-
-
succinimide + H2O
?
show the reaction diagram
-
-
-
-
-
succinimide + H2O
?
show the reaction diagram
-
-
-
-
r
thymine + H2O
?
show the reaction diagram
-
-
-
-
?
uracil + H2O
?
show the reaction diagram
Agrobacterium sp., Agrobacterium sp. IP-I 671
-
-
-
-
?
uric acid + H2O
?
show the reaction diagram
-
-
-
-
?
m-chlorophenylhydantoin + H2O
?
show the reaction diagram
-
-
-
-
?
additional information
?
-
-
-
-
-
-
additional information
?
-
-
-
-
-
-
additional information
?
-
-
-
-
-
-
additional information
?
-
-
-
-
-
-
additional information
?
-
-
DL-5-phenylhydantoin is no substrate
-
-
-
additional information
?
-
-
L-dihydroorotic acid is no substrate
-
-
-
additional information
?
-
-
diphenylhydantoin and 5,5-disubstituted hydantoins like 5-ethyl-5-phenylhydantoin, 5,5-diphenylhydantoin, D-3-methyl-5-phenylhydantoin, D-3-ethyl-5-phenylhydantoin, alpha-methyl-alpha-phenylsuccinimide, N-methyl-alpha-phenylsuccinimide and alpha-ethyl-alpha-phenylglutarimide are no substrates
-
-
-
additional information
?
-
-
hydantoin, urea, allantoin and dihydroorotate are no substrates
-
-
-
additional information
?
-
-
5,5-dimethylhydantoin is no substrate
-
-
-
additional information
?
-
-
succinimide, dihydro-L-orotic-2-acid, dihydrouridine and dihydrothymidine are no substrates
-
-
-
additional information
?
-
-
inactive with carbamoyl beta-alanine amide, barbituric acid, imidazole 4,5-dicarboxylic acid, 5-(carboxymethylidine)hydantoin, orotic acid, 4,5-aminoimidazolecarboximide, urocanic acid and 5-(diphenyl)hydantoin
-
-
-
additional information
?
-
-
disubstituted hydantoins or 1-substituted hydantoins are no substrates
-
-
-
additional information
?
-
-
hydantoins derived from alanine, valine, leucine, serine, phenylalanine and hydroxyphenylglycine are substrates, hydantoins derived from aspartic acid, lysine, and 5,5-disubstituted hydantoins are not hydrolyzed
-
-
-
additional information
?
-
-
DL-hydroxymethylhydantoin and 5,5-disubstituted hydantoin derivatives are no substrates
-
-
-
additional information
?
-
at 0 and 0.01 mM dietary 5-fluorouracil, CRMPsup mutants emerged in numbers similar to those of CRMP+ hemizygotes, survival of CRMPsup mutants was diminished at 0.03 mM 5-fluorouracil
-
-
?
additional information
?
-
-
does not hydrolyze hydantoins
-
-
-
additional information
?
-
-
no activity towards uracil and succinimide
-
-
-
additional information
?
-
-
catalyzes the hydrolysis of 5-monosubstituted hydantoin to enantionmeric N-carbamoyl-amino acids
-
-
-
additional information
?
-
-
enzyme presents both hydantoinase and dihydropyrimidinase activities, with higher affinity for the natural six-membered ring substrates. For the five-membered ring substrates, affinity is greater for those with aliphatic and apolar groups in the 5th carbon atom, with the highest rates of hydrolysis for D-5-methyl and D-5-ethyl hydantoin. Enzyme is enantioselective for the D-isomer of monosubstituted 5-hydantoins. Activity with substrate analogues such as allantoin, 5,5-dimethylhydantoin, 5-benzyl,5-methyl-hydantoin, succinimide, rodamine or tiazoledione is not detected under the conditions assayed
-
-
-
additional information
?
-
no substrate: diphenylhydantoin, 5-(hydroxymethyl)uracil, benzylhydantoin, isopropylhydantoin
-
-
-
additional information
?
-
Rattus norvegicus Sprague-Dawley
-
diphenylhydantoin and 5,5-disubstituted hydantoins like 5-ethyl-5-phenylhydantoin, 5,5-diphenylhydantoin, D-3-methyl-5-phenylhydantoin, D-3-ethyl-5-phenylhydantoin, alpha-methyl-alpha-phenylsuccinimide, N-methyl-alpha-phenylsuccinimide and alpha-ethyl-alpha-phenylglutarimide are no substrates
-
-
-
additional information
?
-
Drosophila melanogaster EP(3)3238
at 0 and 0.01 mM dietary 5-fluorouracil, CRMPsup mutants emerged in numbers similar to those of CRMP+ hemizygotes, survival of CRMPsup mutants was diminished at 0.03 mM 5-fluorouracil
-
-
?
additional information
?
-
Agrobacterium tumefaciens 47C
-
disubstituted hydantoins or 1-substituted hydantoins are no substrates
-
-
-
additional information
?
-
-
DL-hydroxymethylhydantoin and 5,5-disubstituted hydantoin derivatives are no substrates
-
-
-
additional information
?
-
Pseudomonas putida YZ-26
-
catalyzes the hydrolysis of 5-monosubstituted hydantoin to enantionmeric N-carbamoyl-amino acids
-
-
-
additional information
?
-
Pseudomonas putida YZ-26
-
no activity towards uracil and succinimide
-
-
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
?
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
?
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
-
5,6-dihydropyrimidine + H2O
beta-ureido acid
show the reaction diagram
-
-
-
r
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
-
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
r
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
-
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
r
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
Rattus norvegicus Sprague-Dawley
-
-
-
-
-
5,6-dihydrothymine + H2O
?
show the reaction diagram
-
-
-
-
?
5,6-dihydrothymine + H2O
?
show the reaction diagram
Bacillus sp. LU 1220
-
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
r
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Peptococcus anaerobius
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
purified preparation demonstrates no activity on this substrate
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium rubi 30149
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium rubi 30149
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium sp. IP-I 671
-
purified preparation demonstrates no activity on this substrate
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Serratia liquefaciens 1.15
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens CIP 67.1
-
-
-
-
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium rhizogenes 30148
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium rhizogenes 30148
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Geobacillus stearothermophilus JC2310
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Corynebacterium pseudodiphtheriticum 14.10
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 47C
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Bacillus sp. LU 1220
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
5,6-dihydrouracil + H2O
3-ureidopropionate
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
dihydrothymidine + H2O
?
show the reaction diagram
-
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
r
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
ir
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
r
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Peptococcus anaerobius
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium sp. 30201
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Arthrobacter sp. DSM3747
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Arthrobacter sp. DSM3747
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium rubi 30149
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium rubi 30149
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium sp. IP-I 671
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Serratia liquefaciens 1.15
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Pseudomonas sp. AJ-11220
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium rhizogenes 30148
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium rhizogenes 30148
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens 30150
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus SD-1
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus stearothermophilus JC2310
-
-
-
-
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Corynebacterium pseudodiphtheriticum 14.10
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Geobacillus thermocatenulatus GH-2
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium sp. 1-671
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Flavobacterium sp. AJ-3912
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
hydantoin + H2O
N-carbamoyl glycine
show the reaction diagram
Agrobacterium tumefaciens 30147
-
-
-
?
additional information
?
-
Pseudomonas putida, Pseudomonas putida YZ-26
-
catalyzes the hydrolysis of 5-monosubstituted hydantoin to enantionmeric N-carbamoyl-amino acids
-
-
-
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Al3+
-
at 2 mM 112% relative enzyme activity
Ca2+
-
at 2 mM 123% relative enzyme activity
Co2+
-
stimulates production of L-methionine
Co2+
-
enhances activity by more than 60%
Co2+
-
stimulates
Co2+
high stimulation, stimulates enzyme activity most effectively
Co2+
increases activity, when DL-benzyl-hydantoin is used as substrate
Co2+
-
at 2 mM 162% relative enzyme activity
Co2+
-
79% increase of activity at 1 mM
Co2+
-
2 mM, 331% of initial activity
Cu2+
low stimulation
Cu2+
-
at 2 mM 103% relative enzyme activity
Cu2+
-
2 mM, 150% of initial activity
Fe2+
-
needs ferrous ions for activity or reactivation, pure enzyme up to 5 times more active in presence of Fe2+
Fe2+
-
stimulates
Hg2+
-
at 2 mM 0% relative enzyme activity
Mg2+
-
marked acceleration of carbamyl beta-alanine formation from hydrouracil, only slightly stimulatory with hydrothymine as substrate, no effect with hydantoin as substrate
Mg2+
-
at 2 mM 116% relative enzyme activity
Mg2+
-
20% increase of activity at 1 mM
Mg2+
-
2 mM, 121% of initial activity
Mn2+
-
marked acceleration of carbamoyl beta-alanine formation from hydrouracil
Mn2+
-
stimulates production of L-methionine
Mn2+
-
requires 1 ion per molecule of enzyme for activity
Mn2+
-
-
Mn2+
-
depend on
Mn2+
-
stimulates
Mn2+
-
stimulates
Mn2+
high stimulation
Mn2+
-
at 2 mM 116% relative enzyme activity, two manganese ions modelled in the active site
Mn2+
-
96% residual activity at 1 mM; compared to wild-type without metal ions, 1 mM Mn2+ enhances the activity up to 200% for wild-type enzyme P479 and to 400500% for truncates mutants P477, P476, P475 and mutant R479D
Mn2+
-
the hydrolytic activity of PydB is enhanced notably by 0.5 mM Mn2+, about an 8fold increase in the enzymatic activity is observed in the presence of 0.05-5 mM Mn2+
Mn2+
-
74% increase of activity at 1 mM
Ni2+
-
stimulates
Ni2+
-
stimulates
Ni2+
-
at 2 mM 124% relative enzyme activity
Ni2+
-
54% increase of activity at 1 mM
Ni2+
-
2 mM, 346% of initial activity
Zinc
-
a binuclear zinc center activates a water molecule for nucleophilic attack on the substrates amide bond
Zinc
-
in vitro preparation of apo-HDT, i.e. metal-removed HDT, and Zn2+-HDT, i.e. Zn2+-added HDT. The Zn2+-HDT and re-HDT contain 2.17 and 0.95 mol Zn2+ per mol subunit, respectively, and have comparable enzymatic activities. In contrast, the apo-HDT only retains 0.04 mol Zn2+ per mol subunit with less than 10% activity, compared with the re-HDT. When the apo-HDT is reconstituted with ZnCl2, the enzymatic activity recovery is about 75%. Data suggest that the re-HDT may have two Zn2+-binding sites, one is an intrinsic or tight-binding site, zinc-alpha, essential for its activity and the other is a vacant or loose-binding site, zinc-beta, possibly non-essential for the activity
Zn2+
-
essential, metalloenzyme
Zn2+
-
essential, metalloenzyme
Zn2+
-
-
Zn2+
-
stimulates
Zn2+
low stimulation
Zn2+
increases activity, when DL-benzyl-hydantoin is used as substrate
Zn2+
-
catalytic di-zinc center embedded by a (beta/alpha)8-barrel structural core, accompanied by a smaller beta-sandwich domain; contains a di-zinc center
Zn2+
-
at 2 mM 118% relative enzyme activity
Zn2+
-
compared to wild-type without metal ions, 1 mM Zn2+ attenuates the enzymatic activity down to 60% for wild-type enzyme P479 and to more than 90% for mutants R479D and truncated mutants P477, P476 and P475; Zn2+-binding enzyme
Zn2+
-
the presence of Zn2+ does not only increase the percentage of secondary structure, but also the thermal and chemical stability of SmelDhp
Zn2+
-
2 mM, 432% of initial activity
Zn2+
in the active site, a carboxylated lysine residue and the catalytically active hydroxide ion bridge a binuclear zinc centre
Mn2+
-
2 mM, 407% of initial activity
additional information
no stimulation with Mg2+, Ni2+, Ca2+ and Fe2+
additional information
no increase of activity by Fe2+, Mg2+ and Mn2+
additional information
-
non metal ions, 100% relative enzyme activity
additional information
-
binding sites of Zn2+ and Mn2+ may locate at different regions on the enzyme
additional information
-
other divalent metal ions except Mn2+ and Zn2+ do not have significant effect on the enzyme activity
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
1,10-phenanthroline
-
at 1 mM 47% and at 2 mM 46% residual enzyme acitvity
2,2'-dipyridyl
-
-
2,6-dipicolinic acid
-
-
2,6-dipicolinic acid
-
-
2,6-dipicolinic acid
-
-
4-nitrobenzene sulfonamide
-
-
4-ureidobutyric acid
-
-
5-amino-n-valeric acid
-
-
8-hydroxyquinoline
-
-
8-hydroxyquinoline
-
-
8-Hydroxyquinoline-5-sulfonic acid
-
-
8-Hydroxyquinoline-5-sulfonic acid
-
-
8-Hydroxyquinoline-5-sulfonic acid
-
-
8-Hydroxyquinoline-5-sulfonic acid
-
-
beta-Alanine
-
-
Ca2+
-
97% residual activity at 1 mM
Cd2+
-
44% residual activity at 1 mM
Chloramphenicol
-
10.5fold reduced activity in chloramphenicol-treated cells
Cu2+
-
CuSO4*5H2O strongly inhibits L-methionine production
Cu2+
-
0.4% residual activity at 1 mM
D-glucose
-
-
Diethylpyrocarbonate
-
at 2 mM 95% and at 5 mM 80% residual enzyme acitvity
dimethylhydantoin
-
competitive inhibition
EDTA
-
inhibition 43%
EDTA
-
at 5 mM 81% and at 10 mM 71% residual enzyme acitvity
EDTA
-
10 mM, 90% residual activity
glutaric acid monoamide
-
-
Hg2+
-
2 mM, 0% residual activity
L-dihydroorotic acid
-
competitive inhibition
Mercuric chloride
-
1 mM completely abrogates activity
N-bromosuccinimide
-
1 mM completely abrogates activity
N-Carbamoyl-beta-alanine
-
-
N-Carbamoyl-beta-alanine
-
product inhibition
N-carbamoyl-beta-aminoisobutyric acid
-
product inhibition
N-Carbamoyl-glycine
-
competitive inhibition
nitrilotriacetic acid
-
inhibition 42%
o-phenanthroline
-
-
o-phenanthroline
-
-
o-phenanthroline
-
-
p-hydroxymercuribenzoate
-
-
p-hydroxymercuribenzoate
-
-
p-hydroxymercuribenzoate
-
-
p-hydroxymercuribenzoate
-
-
p-hydroxymercuric benzoate
-
1 mM completely abrogates activity
Propionic acid
-
-
propionic acid amide
-
-
rac-5-methyl-5-phenylhydantoic acid
-
competitive
Sn2+
-
-
trans-1,2-cyclohexandiaminetetraacetic acid
-
inhibition 42%
Zn2+
-
irreversible inhibition
Zn2+
-
ZnSO4*7H2O strongly inhibits L-methionine production
Zn2+
-
60% increase of activity at 1 mM
Zn2+
-
a loss of 50% activity is observed in the presence of Zn2+
Zn2+
-
68% residual activity at 1 mM, the dissociation of purified enzyme into its subunits occurrs in the presence of 1 mM Zn2+
Mg2+
-
slightly inhibitory with carbamoyl beta-alanine or carbamoyl beta-aminoisobutyric acid as substrates
additional information
-
not inhibited by N-ethylmaleimide, iodoacetamide, iodoacetic acid, PMSF, phenylglyoxal
-
additional information
-
the use of high sugar to nitrogen ratios in the growth medium results in the formation of extracellular polymers, low biomass, and low enzyme activity
-
additional information
-
not inhibitory: iodoacetamide
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
2-mercaptoethanol
-
10 mM, 108% of initial activity
2-Thiouracil
-
induces biosynthesis of enzyme
dithiothreitol
-
10 mM, 111% of initial activity
Uracil
-
induces biosynthesis of enzyme
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.017
5,6-Dihydrothymine
-
pH 8.2
0.026
5,6-Dihydrothymine
-
pH 7.0
0.008
5,6-dihydrouracil
-
-
0.011
5,6-dihydrouracil
-
-
0.019
5,6-dihydrouracil
-
pH 7.0
0.02
5,6-dihydrouracil
-
pH 8.2
1.7
5,6-dihydrouracil
-
-
11
5,6-dihydrouracil
-
-
117
5,6-dihydrouracil
-
-
0.017
5-bromo-5,6-dihydrouracil
-
pH 8.2
0.025
5-bromo-5,6-dihydrouracil
-
pH 7.0
0.02
5-bromodihydrouracil
-
-
0.018
5-iododihydrouracil
-
-
34
5-isopropylhydantoin
-
-
62.5
5-methylhydantoin
-
-
5.8
allantoin
-
-
0.028
beta-Ureidoisobutyrate
-
0.1 mM
0.069
beta-Ureidoisobutyrate
-
0.1-3.25 mM
0.015
beta-ureidopropionate
-
0.1 mM
0.079
beta-ureidopropionate
-
0.1-5 mM
14.98
D,L-benzylhydantoin
-
free enzyme, at pH 8.5 and 45C
27.03
D,L-benzylhydantoin
-
immobilized enzyme, at pH 8.5 and 45C
5
D-5-benzylhydantoin
-
pH 8.0, 40C
14
D-5-butylhydantoin
-
pH 8.0, 40C
3.4
D-5-ethylhydantoin
-
at 20C
5.1
D-5-ethylhydantoin
-
at 25C
7.9
D-5-ethylhydantoin
-
at 30C
8.2
D-5-ethylhydantoin
-
at 35C
11.6
D-5-ethylhydantoin
-
at 40C
18
D-5-ethylhydantoin
-
pH 8.0, 40C
10
D-5-isobutylhydantoin
-
pH 8.0, 40C
44
D-5-isopropylhydantoin
-
pH 8.0, 40C
66
D-5-methyl-thio-ethylhydantoin
-
pH 8.0, 40C
72
D-5-methylhydantoin
-
pH 8.0, 40C
0.4
D-5-methylthioethylhydantoin
-
at 20C
1.4
D-5-methylthioethylhydantoin
-
at 25C
2.5
D-5-methylthioethylhydantoin
-
at 30C
5.5
D-5-methylthioethylhydantoin
-
at 35C
7
D-5-methylthioethylhydantoin
-
at 40C
26
D-5-propylhydantoin
-
pH 8.0, 40C
0.015
Dihydrothymine
-
-
1.1
dihydrouracil
-
-
2.4
dihydrouracil
-
3
dihydrouracil
-
pH 8.0, 40C
28
DL-5-(2-methylthioethyl)-hydantoin
-
-
28
DL-5-(2-methylthioethyl)-hydantoin
-
-
34
DL-5-(2-methylthioethyl)-hydantoin
-
-
40.7
DL-5-(2-methylthioethyl)hydantoin
-
-
20
DL-5-(p-hydroxyphenyl)hydantoin
-
pH 8.0, 40C
6.8
DL-5-benzylhydantoin
-
-
12.8
DL-5-butylhydantoin
-
-
4.9
DL-5-isobutylhydantoin
-
-
17.2
DL-5-isopropylhydantoin
-
-
1
DL-5-methyldihydrouracil
-
pH 8.0, 40C
27.8
DL-5-methylhydantoin
-
-
7.9
DL-5-phenylhydantoin
-
-
50
DL-5-phenylhydantoin
-
-
58.8
DL-5-phenyllhydantoin
-
-
25.6
DL-5-propylhydantoin
-
-
81
DL-6-isopropyldihydrouracil
-
pH 8.0, 40C
111
DL-6-methyldihydrouracil
-
pH 8.0, 40C
0.074
DL-hydroxyphenylhydantoin
-
-
2.2
DL-hydroxyphenylhydantoin
-
pH 8.0, 37C, mutant enzyme F159L
3.5
DL-hydroxyphenylhydantoin
-
pH 8.0, 37C, mutant enzyme F159I
3.6
DL-hydroxyphenylhydantoin
-
pH 8.0, 37C, mutant enzyme F159V
5.4
DL-hydroxyphenylhydantoin
-
pH 8.0, 37C, wild-