3.5.2.2: dihydropyrimidinase
This is an abbreviated version!
For detailed information about dihydropyrimidinase, go to the full flat file.
Word Map on EC 3.5.2.2
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3.5.2.2
-
5-fluorouracil
-
thymidylate
-
dihydropyridine
-
colorectal
-
fluoropyrimidine
-
phosphorylase
-
thymidine
-
capecitabine
-
l-type
-
uracil
-
nifedipine
-
orotate
-
resect
-
blocker
-
pharmacogenetic
-
1,4-dihydropyridine
-
tegafur
-
prodrugs
-
voltage-dependent
-
dihydrouracil
-
5-fu-based
-
fluoropyrimidine-based
-
nitrendipine
-
leucovorin
-
phosphoribosyltransferase
-
diltiazem
-
oxaliplatin
-
irinotecan
-
hemoperfusion
-
phosphoribosyl
-
5-fluorouracil-based
-
mucositis
-
neutropenia
-
pyrrolizidine
-
11-ketotestosterone
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excitation-contraction
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isradipine
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nisoldipine
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coniferyl
-
5-fu-induced
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dihydropyridine-sensitive
-
felodipine
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5\'-dfur
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dihydroorotase
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photochromic
-
nicardipine
-
synthesis
-
industry
-
5'-deoxy-5-fluorouridine
-
pretherapeutic
-
omega-conotoxin
-
nutrition
-
medicine
-
hand-foot
- 3.5.2.2
- 5-fluorouracil
- thymidylate
-
dihydropyridine
- colorectal
-
fluoropyrimidine
- phosphorylase
- thymidine
- capecitabine
-
l-type
- uracil
- nifedipine
- orotate
-
resect
-
blocker
-
pharmacogenetic
-
1,4-dihydropyridine
-
tegafur
-
prodrugs
-
voltage-dependent
- dihydrouracil
-
5-fu-based
-
fluoropyrimidine-based
-
nitrendipine
- leucovorin
-
phosphoribosyltransferase
- diltiazem
- oxaliplatin
- irinotecan
-
hemoperfusion
-
phosphoribosyl
-
5-fluorouracil-based
- mucositis
- neutropenia
-
pyrrolizidine
- 11-ketotestosterone
-
excitation-contraction
- isradipine
- nisoldipine
-
coniferyl
-
5-fu-induced
-
dihydropyridine-sensitive
- felodipine
-
5\'-dfur
- dihydroorotase
-
photochromic
- nicardipine
- synthesis
- industry
- 5'-deoxy-5-fluorouridine
-
pretherapeutic
-
omega-conotoxin
- nutrition
- medicine
-
hand-foot
Reaction
Synonyms
4,5-dihydropyrimidine amidohydrolase, aaHYD, bar9HYD, bpHYD, bsHYD, CRMP, D-CpHPG, D-HYD, D-hydantionase, D-hydantoin-hydrolyzing enzyme, D-hydantoinase, D-PfHYD, DHP, DHP-1, DHP-2, DHPase, dht, DHTase, dihydropyrimidase/hydantoinase, Dihydropyrimidinase, dihydropyrimidine amidohydrolase, dihydropyrimidine dehydrogenase, HDT, HYD, hydantoin peptidase, hydantoinase, hydropyrimidine hydrase, hyuH, L-Hyd, L-hydantoinase, microbial hydantoinase, P479, PA0441, PaDHPase, PYD2, PydB, pyrimidine hydrase, SmelDhp, thHYD
ECTree
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KM Value
KM Value on EC 3.5.2.2 - dihydropyrimidinase
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8.57
2-chlorobenzenehydantoin
pH 9.0, 45°C, recombinant enzyme
7.52
4-hydroxyphenylhydantoin
pH 9.0, 45°C, recombinant enzyme
additional information
additional information
Michaelis-Menten kinetics
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2.2
DL-hydroxyphenylhydantoin
-
pH 8.0, 37°C, mutant enzyme F159L
3.5
DL-hydroxyphenylhydantoin
-
pH 8.0, 37°C, mutant enzyme F159I
3.6
DL-hydroxyphenylhydantoin
-
pH 8.0, 37°C, mutant enzyme F159V
5.4
DL-hydroxyphenylhydantoin
-
pH 8.0, 37°C, wild-type enzyme
7.4
DL-hydroxyphenylhydantoin
-
pH 8.0, 37°C, mutant enzyme F159A
13
DL-hydroxyphenylhydantoin
-
pH 8.0, 37°C, mutant enzyme L65F/F159A
24
DL-hydroxyphenylhydantoin
-
pH 8.0, 37°C, mutant enzyme M63F/L65V
27
DL-hydroxyphenylhydantoin
-
pH 8.0, 37°C, mutant enzyme F159S
2.9
mutant M63I/F159S, pH 8.0, 37°C
4.9
DL-p-hydroxyphenylhydantoin
wild-type, pH 8.0, 37°C
5.1
DL-p-hydroxyphenylhydantoin
mutant M63H/F159N, pH 8.0, 37°C