3.4.22.49: separase

This is an abbreviated version!
For detailed information about separase, go to the full flat file.

Word Map on EC 3.4.22.49

3.4.22.49

chromatid

sister

anaphase

cohesin

mitosis

securin

spindle

metaphase

meiotic

checkpoint

centromeres

kinetochore

anaphase-promoting

scc1

prophase

aneuploidy

rec8

cdc14

rad21

metaphase-to-anaphase

centrosome

shugoshins

centriole

sister-chromatid

metaphase-anaphase

disjunction

medicaid

disengagement

prometaphase

missegregation

polo-like

biorientation

cyclosome

kleisin

meiosis-specific

chiasmata

pds1

condensins

medicine

diagnostics

nondisjunction

molecular biology

cdk1-dependent

pp2acdc55

kinetochore-microtubule

Reaction

all bonds known to be hydrolysed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by an hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage =

Results	in table
18	Activating Compound
3097	AA Sequence
10	Application
1	CAS Registry Number
17	Cloned(Commentary)
4	Crystallization (Commentary)
395	Disease/ Diagnostics
2	Expression
93	General Information
1	General Stability
10	IC50 Value
74	Inhibitors
1	KM Value [mM]
24	Localization
4	Metals/Ions
6	Molecular Weight [Da]
87	Natural Substrates/ Products (Substrates)
127	Organism
4	PDB ID
1	pH Optimum
1	pH Range
27	Posttranslational Modification
31	Protein Variants
4	Purification (Commentary)
3	Reaction
13	Reaction Type
124	Reference
49	Source Tissue
2	Specific Activity [micromol/min/mg]
4	Storage Stability
116	Substrates and Products (Substrate)
3	Subunits
48	Synonyms
1	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]

3.4.22.49: separase

Reaction

Synonyms

ECTree

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Organism

Organism on EC 3.4.22.49 - separase