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Literature summary for 3.4.22.49 extracted from
- Together until separin do us part (2001), Nat. Cell Biol., 3, E12-14.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cohesin + H2O | Homo sapiens | - |
cleaved cohesin | - |
? |  |
| cohesin + H2O | Saccharomyces cerevisiae | - |
cleaved cohesin | - |
? | |
| cohesin + H2O | Schizosaccharomyces pombe | - |
cleaved cohesin | - |
? | |
| Rad21 + H2O | Schizosaccharomyces pombe | Rad21 is cleaved by Cut1 at the metaphase-anaphase transition | cleaved Rad21 | - |
? | |
| Rec8 + H2O | Saccharomyces cerevisiae | cleavage of meiosis-specific Scc1 variant Rec8 is required for chromosome segregation during meiosis | cleaved Rac8 | - |
? | |
| Scc1 + H2O | Homo sapiens | - |
cleaved Scc1 | - |
? | |
| Scc1 + H2O | Saccharomyces cerevisiae | - |
cleaved Scc1 | - |
? | |
| Scc1 + H2O | Schizosaccharomyces pombe | - |
cleaved Scc1 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
| Schizosaccharomyces pombe | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cohesin + H2O | - |
Homo sapiens | fragments of cohesin | - |
? | |
| cohesin + H2O | - |
Saccharomyces cerevisiae | fragments of cohesin | - |
? | |
| cohesin + H2O | - |
Schizosaccharomyces pombe | fragments of cohesin | - |
? | |
| cohesin + H2O | - |
Homo sapiens | cleaved cohesin | - |
? | |
| cohesin + H2O | - |
Saccharomyces cerevisiae | cleaved cohesin | - |
? | |
| cohesin + H2O | - |
Schizosaccharomyces pombe | cleaved cohesin | - |
? | |
| Rad21 + H2O | Rad21 is cleaved by the separase Cut1 at the metaphase-anaphase transition | Schizosaccharomyces pombe | fragments of Rad21 | - |
? | |
| Rad21 + H2O | Rad21 is cleaved by Cut1 at the metaphase-anaphase transition | Schizosaccharomyces pombe | cleaved Rad21 | - |
? | |
| Rec8 + H2O | cleavage of meiosis-specific Scc1 variant Rec8 is required for chromosome segregation during meiosis | Saccharomyces cerevisiae | fragments of Rac8 | - |
? | |
| Rec8 + H2O | cleavage of meiosis-specific Scc1 variant Rec8 is required for chromosome segregation during meiosis | Saccharomyces cerevisiae | cleaved Rac8 | - |
? | |
| Scc1 + H2O | - |
Saccharomyces cerevisiae | fragments of Scc1 | - |
? | |
| Scc1 + H2O | - |
Homo sapiens | cleaved Scc1 | - |
? | |
| Scc1 + H2O | - |
Saccharomyces cerevisiae | cleaved Scc1 | - |
? | |
| Scc1 + H2O | - |
Schizosaccharomyces pombe | cleaved Scc1 | - |
? | |
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