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Literature summary for 3.4.22.49 extracted from
- Cut1/separase-dependent roles of multiple phosphorylation of fission yeast cohesion subunit Rad21 in post-replicative damage repair and mitosis (2008), Cell Cycle, 7, 765-776.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| generation of separase gene knock-out mutants | Schizosaccharomyces pombe |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Schizosaccharomyces pombe | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| all bonds known to be hydrolysed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by an hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage | unphosphorylatable form of cohesin subunit Rad21 is less efficiently cleaved by Separase | Schizosaccharomyces pombe |
aSynonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Cut1/separase | - |
Schizosaccharomyces pombe |
| separase | - |
Schizosaccharomyces pombe |
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Release 2023.1 (January 2023)
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