Literature summary for 3.4.22.49 extracted from

Pemberton, H.N.; Franklyn, J.A.; Boelaert, K.; Chan, S.Y.; Kim, D.S.; Kim, C.; Cheng, S.Y.; Kilby, M.D.; McCabe, C.J.
Separase, securin and Rad21 in neural cell growth (2007), J. Cell. Physiol., 213, 45-53.

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Application

Application	Comment	Organism
molecular biology	data suggest that the co-ordinated expression of separase, securin and Rad21 is fundamental for the developing brain	Mus musculus
molecular biology	data suggest that the co-ordinated expression of separase, securin and Rad21 is fundamental for the developing brain	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	in a murine model of absent securin expression, the PTTG knock-out mouse, separase and Rad21 are over-expressed in multiple brain regions. Furthermore, Rad21 mRNA expression is highly correlated with that of securin, separase, cyclin C and sestrin 2 in fetal brains	Mus musculus	-
cerebral cortex	highly expressed in human fetal cerebral cortex compared with adult	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
separase	-	Mus musculus
separase	-	Homo sapiens

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Release 2023.1 (January 2023)