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3.4.22.27: cathepsin S

This is an abbreviated version!
For detailed information about cathepsin S, go to the full flat file.

Word Map on EC 3.4.22.27

Reaction

similar to cathepsin L, but with much less activity on Z-Phe-Arg-/-NHMec, and additional information activity on the Z-Val-Val-Arg-/- compound =

Synonyms

C01.034, Cat S, Cat-S, cath S, cathepsin S, cathepsin S-like cysteine proteinase, cathepsin Sa, CatS, CatSPP, CTSS, Hacp-s, PfCTSSa, PoCtS, rs1136774, rs16827671, rs34495036, rs35989725, rs3754212, rs7534124, SoCatS

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.27 cathepsin S

Cloned

Cloned on EC 3.4.22.27 - cathepsin S

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
apolipoprotein-deficient with minus or plus catS are assigned to chronic renal disease
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chimeric LDLr-/-mice deficient in leucocyte cathepsin S are generated by bone marrow transplantation
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DELTAW52-N63 mutant procathepsin S is expressed in HEK 293 cells as a stable protein. However it is not processed to mature cathepsin S as is the wild-type procathepsin S
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DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis
expressed as inclusion bodies in Escherichia coli
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expressed by using the baculovirus expression system
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expressed in baculovirus
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expressed in Escherichia coli
expressed in Escherichia coli strain BL21 (DE3)
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expressed in Pichia pastoris
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expression as a glutathione S-transferase-fusion protein
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expression in baby hamster kidney cells and transport to lysosomes via the mannose 6-phosphate receptor pathway
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expression in baculovirally infected Sf9 insect cells along with humanized forms truncated by eight residues at the amino-terminus
expression in Escherichia coli strain BL21(DE3) in inclusion bodies
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expression of Cat S
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gene CTSS, real-time PCR enzyme expression analysis
gene PfCTSSa, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenic analysis, quantitative expression analysis, recombinant expression in Escherichia coli strain BL21(DE3)
genetic profiling and expression analysis of CatS in adipose tissue of non-obese and obese individuals
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His-tagged version expressed in Escherichia coli
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human CatS is obtained by autocatalytic processing of the zymogene expressed in Escherichia coli
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human recombinant cathepsin S expressed in a murine myeloma NS0 cells is used
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human recombinant CatS expressed in Escherichia coli
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recombinant expression in Escherichia coli
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the cathepsin S propeptide is expressed in Escherichia coli BL21(DE3) cells
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the cDNA encoding proenzyme of PoCtS is expressed in Escherichia coli as a fusion protein with glutathione S-transferase in a pGEX-4T-1 vector. The recombinant proPoCtS protein is overexpressed in Escherichia coli BL21(DE3) as a 60 kDa fusion protein
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the gene encoding Cat S is located on chromosome 1q21
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wild type human CatS is cloned into pcDNA3, CatS overexpression is involved in radioresistance
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