3.4.22.27: cathepsin S
This is an abbreviated version!
For detailed information about cathepsin S, go to the full flat file.
Word Map on EC 3.4.22.27
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3.4.22.27
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cathepsins
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lysosomal
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point-of-care
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cystatins
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dendritic
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atherosclerosis
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proteinases
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elastin
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papain
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antigen-presenting
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histocompatibility
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autoimmune
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drug development
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lacrimal
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papain-like
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diagnostics
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ii-associated
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elastolytic
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resource-limited
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s-deficient
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procathepsins
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l-like
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pharmacology
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endostatin
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microglial
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fractalkine
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medicine
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par2
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collagenolytic
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syphilis
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ii-restricted
- 3.4.22.27
- cathepsins
- lysosomal
-
point-of-care
- cystatins
- dendritic
- atherosclerosis
- proteinases
- elastin
- papain
-
antigen-presenting
-
histocompatibility
- autoimmune
- drug development
-
lacrimal
-
papain-like
- diagnostics
-
ii-associated
-
elastolytic
-
resource-limited
-
s-deficient
-
procathepsins
-
l-like
- pharmacology
- endostatin
- microglial
- fractalkine
- medicine
- par2
-
collagenolytic
- syphilis
-
ii-restricted
Reaction
similar to cathepsin L, but with much less activity on Z-Phe-Arg-/-NHMec, and additional information activity on the Z-Val-Val-Arg-/- compound =
Synonyms
C01.034, Cat S, Cat-S, cath S, cathepsin S, cathepsin S-like cysteine proteinase, cathepsin Sa, CatS, CatSPP, CTSS, Hacp-s, PfCTSSa, PoCtS, rs1136774, rs16827671, rs34495036, rs35989725, rs3754212, rs7534124, SoCatS
ECTree
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Expression
Expression on EC 3.4.22.27 - cathepsin S
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CTSS gene expression is increased after cells have been treated with recombinant CTSS for 24 h. CTSS protein expression in cell lysates measured using the human CTSS ELISA kit also reveal that the protein increases after 8 h CTSS treatment
PoCtS expression increased significantly in muscle 6 h post-injection of bacterial lipopolysaccharide
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SoCatS expression is enhanced by bacterial infection with fish pathogenic Edwardsiella tarda, a fish pathogen. In kidney, significant induction of SoCatS occurs at 4 h (2.31fold) and 8 h (2.55fold) post-infection. In liver, significant induction of SoCatS (3.0fold) is only observed at 24 h post-infection. In spleen, SoCatS expression is significantly upregulated at 12 h post-infection (5.46fold) and at 24 h post-infection (4.23fold)