3.2.1.52: beta-N-acetylhexosaminidase

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For detailed information about beta-N-acetylhexosaminidase, go to the full flat file.

Word Map on EC 3.2.1.52

3.2.1.52

urinary

tay-sachs

gm2

beta-galactosidase

beta-glucuronidase

urine

n-acetylglucosamine

mast

isoenzymes

o-glcnacylation

hydrolases

ganglioside

sandhoff

creatinine

o-linked

oligosaccharide

tubular

degranulation

alpha-mannosidase

gangliosidosis

glycosidases

ige

cathepsins

infantile

beta-glucosidase

rbl-2h3

n-acetyl-beta-d-glucosaminidase

histamine

nephrotoxicity

hexosamine

basophil

alpha-galactosidase

arylsulfatase

chitinases

alpha-fucosidase

chitinolytic

jewish

ashkenazi

exoglycosidases

ige-mediated

n-acetylgalactosamine

2-microglobulin

fcepsilonri

endochitinase

4-methylumbelliferyl

3.2.1.23

mucolipidosis

anti-allergic

arylamidase

chitobiose

drug development

diagnostics

medicine

food industry

analysis

Reaction

+ 3 H2O = 4 2-(acetylamino)-2-deoxy-beta-D-glucopyranose

Synonyms

2-acetamido-2-deoxy-beta-D-glucoside acetamidodeoxyglucohydrolase, 3-beta-N-acetylglucosaminidase, 65 kDa epididymal boar protein, Am2301, Am2446, At1g65600/F5I14_13, beta-acetylaminodeoxyhexosidase, beta-acetylhexosaminidase, beta-acetylhexosaminidinase, beta-D-hexosaminidase, beta-D-N-acetylhexosaminidase, Beta-GlcNAcase, beta-glucosidase, beta-HEX, beta-HexNAcase, beta-hexosaminidase, beta-hexosaminidase A, beta-hexosaminidase B, beta-hexosaminidase I, beta-hexosaminidase II, beta-N-acetyl-D-glucosaminidase, beta-N-acetyl-D-hexosaminidase, beta-N-acetyl-hexosaminidase, beta-N-acetylgalactosaminidase, beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, beta-N-acetylhexosaminidase A, beta-N-acetylhexosaminidase B, beta-Nacetylhexosaminidase S, beta-NAGase, beta-NAHA, Beta-NAHASE, bifunctional exo-beta-glucosidase/N-acetyl-beta-glucosaminidase, BmCHI-h, BmGlcNAcase 1, BmGlcNAcase 2, BmNPV CHIA, CbsA, Chi-I, Chi-II, chitobiase, chitobiase 2, CpGV V-CHIA, dispersin B, DmHEXA, DmHEXB, DspB, EC 3.2.1.29, EC 3.2.1.30, endo-beta-N-acetylglucosaminidase, EXC1Y, EXC2Y, exo-acting chitinase, exo-beta-D-N-acetylglucosaminidase, exo-beta-hexosaminidase, exo-type beta-N-acetylhexosaminidase, exochitinase, F3F20.4 protein, FDL, GH84C, GlcNAcase, Hex, Hex A, Hex B, Hex-1, Hex1, Hex2, Hex20, Hex4, HexB, HexD, HEXDC, hEXO1, HEXO2, HEXO3, hexosaminidase, hexosaminidase A, hexosaminidase B, hexosaminidase D, hHexA, lacto-N-biosidase, lnba, lysosomal beta-hexosaminidase, More, N-acetyl-beta-D-hexosaminidase, N-acetyl-beta-glucosaminidase, N-acetyl-beta-hexosaminidase, N-acetylglucosaminidase, N-acetylhexosaminidase, NAG-68, NAG-B, NAG1, NAG2, Nag3, NagA, NAGase, NagJ, NagZ, NAHA, NAHase, neutral hexosaminidase C, O-GlcNAcase, Pcb-NAHA1, Sfhex, SSO3039, StrH, zymocin alpha-subunit

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.52 beta-N-acetylhexosaminidase

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Results	in table
74	Activating Compound
52983	AA Sequence
26	Application
2	CAS Registry Number
43	Cloned(Commentary)
14	Crystallization (Commentary)
4230	Disease/ Diagnostics
2	Expression
8	General Information
13	General Stability
50	IC50 Value
727	Inhibitors
66	kcat/KM [mM/s]
86	Ki Value [mM]
345	KM Value [mM]
72	Localization
32	Metals/Ions
204	Molecular Weight [Da]
118	Natural Substrates/ Products (Substrates)
29	Organic Solvent Stability
307	Organism
11	Pathway
312	PDB ID
161	pH Optimum
48	pH Range
57	pH Stability
10	pI Value
57	Posttranslational Modification
61	Protein Variants
138	Purification (Commentary)
33	Reaction
1	Reaction Type
294	Reference
233	Source Tissue
166	Specific Activity [micromol/min/mg]
49	Storage Stability
926	Substrates and Products (Substrate)
120	Subunits
250	Synonyms
1	Systematic Name
66	Temperature Optimum [°C]
21	Temperature Range [°C]
105	Temperature Stability [°C]
142	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 3.2.1.52 - beta-N-acetylhexosaminidase

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100000

3 entries

100000 - 110000

Homo sapiens

hexosaminidase I2, gradient gel electrophoresis

393658

10077

Sotalia fluviatilis

x * 10077, SDS-PAGE and mass spectrometry

103000

SDS-PAGE

105000

sedimentation equilibrium using untreated enzyme, carboxymethylated enzyme in 6 M guanidine-HCl, meniscus depletion experiments with fresh enzyme prepatation at pH 11.5