3.2.1.52: beta-N-acetylhexosaminidase

This is an abbreviated version!
For detailed information about beta-N-acetylhexosaminidase, go to the full flat file.

Reaction

Synonyms

2-acetamido-2-deoxy-beta-D-glucoside acetamidodeoxyglucohydrolase, 3-beta-N-acetylglucosaminidase, 65 kDa epididymal boar protein, Am2301, Am2446, At1g65600/F5I14_13, beta-acetylaminodeoxyhexosidase, beta-acetylhexosaminidase, beta-acetylhexosaminidinase, beta-D-hexosaminidase, beta-D-N-acetylhexosaminidase, Beta-GlcNAcase, beta-glucosidase, beta-HEX, beta-HexNAcase, beta-hexosaminidase, beta-hexosaminidase A, beta-hexosaminidase B, beta-hexosaminidase I, beta-hexosaminidase II, beta-N-acetyl-D-glucosaminidase, beta-N-acetyl-D-hexosaminidase, beta-N-acetyl-hexosaminidase, beta-N-acetylgalactosaminidase, beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, beta-N-acetylhexosaminidase A, beta-N-acetylhexosaminidase B, beta-Nacetylhexosaminidase S, beta-NAGase, beta-NAHA, Beta-NAHASE, bifunctional exo-beta-glucosidase/N-acetyl-beta-glucosaminidase, BmCHI-h, BmGlcNAcase 1, BmGlcNAcase 2, BmNPV CHIA, CbsA, Chi-I, Chi-II, chitobiase, chitobiase 2, CpGV V-CHIA, dispersin B, DmHEXA, DmHEXB, DspB, EC 3.2.1.29, EC 3.2.1.30, endo-beta-N-acetylglucosaminidase, EXC1Y, EXC2Y, exo-acting chitinase, exo-beta-D-N-acetylglucosaminidase, exo-beta-hexosaminidase, exo-type beta-N-acetylhexosaminidase, exochitinase, F3F20.4 protein, FDL, GH84C, GlcNAcase, Hex, Hex A, Hex B, Hex-1, Hex1, Hex2, Hex20, Hex4, HexB, HexD, HEXDC, hEXO1, HEXO2, HEXO3, hexosaminidase, hexosaminidase A, hexosaminidase B, hexosaminidase D, hHexA, lacto-N-biosidase, lnba, lysosomal beta-hexosaminidase, More, N-acetyl-beta-D-hexosaminidase, N-acetyl-beta-glucosaminidase, N-acetyl-beta-hexosaminidase, N-acetylglucosaminidase, N-acetylhexosaminidase, NAG-68, NAG-B, NAG1, NAG2, Nag3, NagA, NAGase, NagJ, NagZ, NAHA, NAHase, neutral hexosaminidase C, O-GlcNAcase, Pcb-NAHA1, Sfhex, SSO3039, StrH, zymocin alpha-subunit

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

                3.2.1.52 beta-N-acetylhexosaminidase

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Results	in table
74	Activating Compound
52983	AA Sequence
26	Application
2	CAS Registry Number
43	Cloned(Commentary)
14	Crystallization (Commentary)
4230	Disease/ Diagnostics
2	Expression
8	General Information
13	General Stability
50	IC50 Value
727	Inhibitors
66	kcat/KM [mM/s]
86	Ki Value [mM]
345	KM Value [mM]
72	Localization
32	Metals/Ions
204	Molecular Weight [Da]
118	Natural Substrates/ Products (Substrates)
29	Organic Solvent Stability
307	Organism
11	Pathway
312	PDB ID
161	pH Optimum
48	pH Range
57	pH Stability
10	pI Value
57	Posttranslational Modification
61	Protein Variants
138	Purification (Commentary)
33	Reaction
1	Reaction Type
294	Reference
233	Source Tissue
166	Specific Activity [micromol/min/mg]
49	Storage Stability
926	Substrates and Products (Substrate)
120	Subunits
250	Synonyms
1	Systematic Name
66	Temperature Optimum [°C]
21	Temperature Range [°C]
105	Temperature Stability [°C]
142	Turnover Number [1/s]

Organism

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Organism on EC 3.2.1.52 - beta-N-acetylhexosaminidase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Acremonium persicinum

2 entries

Acremonium persicinum CCF1850

-

697320

-

-

brenda

Acremonium persicinum P-10

P-10

393669

-

-

brenda

Aeromonas hydrophila

-

696836

-

-

brenda

Aeromonas hydrophila SUWA-9

-

696836

-

-

brenda

Aeromonas sp.

DYU-Too7

678855

-

-

brenda

Aeromonas sp. DYU-Too7

DYU-Too7

678855

-

-

brenda

Aggregatibacter actinomycetemcomitans

-

679793

-

-

brenda

Akkermansia muciniphila

-

750241

-

-

brenda

Akkermansia muciniphila DSM 22959

-

750241

-

-

brenda

Arabidopsis thaliana

-

682425

A7WM73, Q8L7S6, Q9SYK0

SwissProt

brenda

Armadillo officinalis

-

26851

-

-

brenda

Aspergillus awamori

-

697320

-

-

brenda

Aspergillus awamori CCF763

-

697320

-

-

brenda

Aspergillus flavipes

-

664773

-

-

brenda

Aspergillus flavofurcatus

-

697320

-

-

brenda

Aspergillus flavofurcatus CCF3061

-

697320

-

-

brenda

Aspergillus flavus

-

664773

-

-

brenda

Aspergillus niger

-

393713, 680303

-

-

brenda

Aspergillus niveus

-

697320

-

-

brenda

Aspergillus niveus CCF3057

-

697320

-

-

brenda

Aspergillus nomiae

-

697320

-

-

brenda

Aspergillus nomiae CCF3086

-

697320

-

-

brenda

Aspergillus oryzae

5 entries

Aspergillus oryzae CCF 1066

-

678258, 713667

Q8J2T0

UniProt

brenda

Aspergillus oryzae CCF1066

2 entries

Aspergillus parasiticus

-

664773, 697320

-

-

brenda

Aspergillus parasiticus CCF1298

-

697320

-

-

brenda

Aspergillus sp.

S1-13

680953

-

-

brenda

Aspergillus sp. S1-13

S1-13

680953

-

-

brenda

Aspergillus tamarii

-

664773, 697320

-

-

brenda

Aspergillus tamarii CCF3085

-

697320

-

-

brenda

Aspergillus versicolor

2 entries

Aspergillus versicolor CCF 2491

-

749716

A0A1L9P8I4

UniProt

brenda

Aspergillus versicolor CCF2491

-

697320

-

-

brenda

Bacillus sp. (in: Bacteria)

B. subtilis

393722, 393723

-

-

brenda

Bacillus sp. CH11

-

751231

-

-

brenda

Bacillus subtilis

-

750077

P40406

UniProt

brenda

Bacillus subtilis 168

-

750077

P40406

UniProt

brenda

Bacteroides thetaiotaomicron

BtGH84 complex

682225

-

-

brenda

Bipolaris sorokiniana

-

393692

-

-

brenda

Bombyx mori

6 entries

Bombyx mori nucleopolyhedrovirus

-

677924

-

-

brenda

Bos taurus

4 entries

Brassica oleracea

-

393687

-

-

brenda

Caenorhabditis elegans

-

680815

Q22492

SwissProt

brenda

Canavalia ensiformis

2 entries

Canavalia sp.

-

697342, 707729

-

-

brenda

Candida albicans

ATCC 10261

393730

-

-

brenda

Capsicum annuum

2 entries

Carica papaya

-

656947, 715073

-

-

brenda

Cellulomonas fimi

-

664914

-

-

brenda

Citrullus lanatus

watermelon

135988

-

-

brenda

Clostridium perfringens

gene nagJ

709082

Q8XL08

UniProt

brenda

Coccidioides posadasii

2 entries

Coccidioides posadasii Silveira

2 entries

Conidiobolus lamprauges

-

393711

-

-

brenda

Crithidia fasciculata

sandfly, Phlebotomus papatasi, infected

393551

-

-

brenda

Cupiennius salei

-

393507

-

-

brenda

Cydia pomonella granulovirus

-

677870

-

-

brenda

Dictyostelium discoideum

-

393719

-

-

brenda

Dictyostelium discoideum A3

-

393719

-

-

brenda

Drosophila melanogaster

-

680039, 682592, 698129

-

-

brenda

Escherichia coli

-

393718

-

-

brenda

Felis catus

-

700234

P49614

UniProt

brenda

Fusarium oxysporum

-

697320

-

-

brenda

Fusarium oxysporum CCF377

-

697320

-

-

brenda

Gallus gallus

-

393661, 654151

-

-

brenda

Geobacillus stearothermophilus

CH-4

393696

-

-

brenda

Geobacillus stearothermophilus CH-4

CH-4

393696

-

-

brenda

Glycine max

soybean

393652

-

-

brenda

Halocynthia roretzi

-

393663

-

-

brenda

Helicella ericetorum

Müller

393671

-

-

brenda

Helicella ericetorum Muller

Müller

393671

-

-

brenda

Herpetomonas muscarum

sandfly, Phlebotomus papatasi, infected

393551

-

-

brenda

Homo sapiens

15 entries

Hordeum vulgare

barley, malted

393727

-

-

brenda

Kluyveromyces lactis

-

678108

-

-

brenda

Lactococcus lactis

ssp. lactis, gene lnbA

731962

Q9CFI2

UniProt

brenda

Lactococcus lactis IL1403

ssp. lactis, gene lnbA

731962

Q9CFI2

UniProt

brenda

Leishmania braziliensis

sandfly, Phlebotomus papatasi, infected

393551

-

-

brenda

Leishmania donovani

sandfly, Phlebotomus papatasi, infected

393551

-

-

brenda

Leishmania infantum

sandfly, Phlebotomus papatasi, infected

393551

-

-

brenda

Leishmania major

sandfly, Phlebotomus papatasi, infected

393551

-

-

brenda

Leptomonas seymouri

sandfly, Phlebotomus papatasi, infected

393551

-

-

brenda

Leuciscus idus

-

749583

-

-

brenda

Limulus polyphemus

horseshoe crab

393716

-

-

brenda

Lupinus luteus

-

393698, 393699

-

-

brenda

Mangifera indica

-

656947

-

-

brenda

Mizuhopecten yessoensis

-

393695

-

-

brenda

Mucor fragilis

-

393657

-

-

brenda

Mugil cephalus

striped mullet

393654

-

-

brenda

Mus musculus

2 entries

Musca sp.

banana

656947

-

-

brenda

Mycobacterium leprae

from armadillo liver

26851

-

-

brenda

Mycobacterium tuberculosis variant microti

-

26851

-

-

brenda

Mycolicibacterium phlei

-

26851

-

-

brenda

Nilaparvata lugens

brown planthopper

750933

A0A0C5CE51

UniProt

brenda

Octopus vulgaris

-

393710

-

-

brenda

Oryctolagus cuniculus

2 entries

Oryza sativa

L. var. Dongjin

655935

-

-

brenda

Ostrinia furnacalis

4 entries

Ovis aries

male

393732

-

-

brenda

Paenibacillus sp. TS12

isolated as a GSL-degrading bacterium from soil in Fukuoka Prefecture, Japan, isozymes Hex1 and Hex2

709527

-

-

brenda

Palaemon carinicauda

ridgetail white prawn

750692

A0A2P1BRR8

UniProt

brenda

Palythoa caribaeorum

-

682691

-

-

brenda

Patella vulgata

-

208685, 393720

-

-

brenda

Penaeus japonicus

prawn

393697

-

-

brenda

Penaeus vannamei

white leg shrimp

709182

-

-

brenda

Penicillium brasilianum

-

697320

-

-

brenda

Penicillium brasilianum CCF2171

-

697320

-

-

brenda

Penicillium chrysogenum

-

697320

-

-

brenda

Penicillium chrysogenum CCF1269

-

697320

-

-

brenda

Penicillium oxalicum

3 entries

Penicillium oxalicum CCF 1959

-

715126

-

-

brenda

Penicillium oxalicum CCF 3438

-

714981

-

-

brenda

Phlebotomus papatasi

desert and oasis flies studied, male and female, Neot Hakikar (oasis), Jordan Valley spring (wet), Kfar Adumim starved (arid), Jordan Valley autumn (arid)

679943

-

-

brenda

Phycomyces blakesleeanus

NRRL1555(-)

393706

-

-

brenda

Phycomyces blakesleeanus NRRL1555(-)

NRRL1555(-)

393706

-

-

brenda

Pisum sativum

pea

393656

-

-

brenda

Prunus serotina

black cherry

393659

-

-

brenda

Pseudohamigera striata

-

697320

-

-

brenda

Pseudohamigera striata CCF2232

-

697320

-

-

brenda

Rattus norvegicus

2 entries

Rhinella arenarum

-

656839

-

-

brenda

Rhipicephalus microplus

bovine tick, ixodide

393682

-

-

brenda

Saccharolobus solfataricus

-

724468

Q97UH8

UniProt

brenda

Saccharolobus solfataricus P2

-

724468

Q97UH8

UniProt

brenda

Salinivibrio costicola

-

677567

-

-

brenda

Salinivibrio costicola 5SM-1

-

677567

-

-

brenda

Sclerotinia fructigena

-

393724

-

-

brenda

Scylla serrata

green crab

709181

-

-

brenda

Serratia marcescens

YS-1

655769

-

-

brenda

Serratia marcescens Ys-1

YS-1

655769

-

-

brenda

Solanum lycopersicum

-

656947, 680128

-

-

brenda

Sotalia fluviatilis

-

710485

-

-

brenda

Spodoptera frugiperda

-

665721

Q3LS76

SwissProt

brenda

Stachybotrys elegans

-

655153

-

-

brenda

Stackebrandtia nassauensis

-

750872

D3PZ76

UniProt

brenda

Stackebrandtia nassauensis DSM 44728

-

750872

D3PZ76

UniProt

brenda

Streptococcus pneumoniae

member of glycosyl hydrolase family 20

715648

Q8DRL6

UniProt

brenda

Streptomyces alfalfae

-

751148

A0A3G3NI51

UniProt

brenda

Streptomyces alfalfae ACCC40021

-

751148

A0A3G3NI51

UniProt

brenda

Streptomyces plicatus

2 entries

Streptomyces sp.

3 entries

Streptomyces sp. L-13

-

393703

-

-

brenda

Styela plicata

sea-squirt

393665

-

-

brenda

Sus scrofa

-

393686, 393709

-

-

brenda

Symbiobacterium thermophilum

-

664798

-

-

brenda

Talaromyces flavus

2 entries

Talaromyces flavus CCF 2573

-

715126

-

-

brenda

Talaromyces flavus CCF2686

-

750184

-

-

brenda

Talaromyces ohiensis

-

697320

-

-

brenda

Talaromyces ohiensis CCF2229

-

697320

-

-

brenda

Talaromyces pittii

-

697320

-

-

brenda

Talaromyces pittii CCF2277

-

697320

-

-

brenda

Thermotoga maritima MSB8

gene nagA

709186

Q9WZR6

UniProt

brenda

Thermotoga neapolitana

gene cbsA

709186

-

-

brenda

Thermotoga neapolitana KCCM 41025

gene cbsA

709186

-

-

brenda

Trametes cinnabarina

2 entries

Tremella fuciformis

-

136038

-

-

brenda

Tremella fuciformis T-7

-

136038

-

-

brenda

Tribolium castaneum

GA-1 strain

698278

A5YVX3, A5YVX4, A5YVX5, A5YVX6

UniProt

brenda

Tribolium castaneum GA-1

GA-1 strain

698278

A5YVX3, A5YVX4, A5YVX5, A5YVX6

UniProt

brenda

Trichinella spiralis

-

666290

-

-

brenda

Trichoderma harzianum

4 entries

Trichoderma harzianum CCF2687

-

697320

-

-

brenda

Trichomonas vaginalis

-

655514, 664296

-

-

brenda

Trigonella foenum-graecum

-

393673, 393674

-

-

brenda

Triticum aestivum

wheat

393650

-

-

brenda

Tritrichomonas suis

-

393675

-

-

brenda

Trypanosoma lewisi

sandfly, Phlebotomus papatasi, infected

393551

-

-

brenda

Turbatrix aceti

-

393708

-

-

brenda

Turbo cornutus

-

393695

-

-

brenda

uncultured Actinomycetales bacterium

-

750318

A0A0E3XI19

UniProt

brenda

uncultured Bacteroidetes bacterium

-

750318

A0A0E3XHF8

UniProt

brenda

Vibrio furnissii

-

393685

P96155

Uniprot

brenda

Zea mays

L. cv. Snowdent 110

656623

-

-

brenda

Acremonium persicinum

-

697320

-

-

brenda

Acremonium persicinum

P-10

393669

-

-

brenda

Aspergillus oryzae

-

664773

-

-

brenda

Aspergillus oryzae

-

678258

Q8J2T0

UniProt

brenda

Aspergillus oryzae

-

678882, 678947, 679060

-

-

brenda

Aspergillus oryzae

-

713667, 750525

Q8J2T0

UniProt

brenda

Aspergillus oryzae

strains CCF147 and CCF1066

697320

-

-

brenda

Aspergillus oryzae CCF1066

-

678947

-

-

brenda

Aspergillus oryzae CCF1066

-

750525

Q8J2T0

UniProt

brenda

Aspergillus versicolor

-

697320

-

-

brenda

Aspergillus versicolor

-

749716

A0A1L9P8I4

UniProt

brenda

Bombyx mori

-

677924

-

-

brenda

Bombyx mori

5-day old pupae

393705

-

-

brenda

Bombyx mori

full-grown fifth-instar larvae

393717

-

-

brenda

Bombyx mori

isozyme A or BmGlcNAcase 2; isozyme BmGlcNAcase 2

708584

Q3L6N4

UniProt

brenda

Bombyx mori

isozyme BmGlcNAcase 1; isozyme BmGlcNAcase 1

708584

P49010

UniProt

brenda

Bombyx mori

silkworm, pupae and fifth-instar larvae at the SP3 stage

393704

-

-

brenda

Bos taurus

-

393672, 393676, 393707, 393715, 393725, 697342

-

-

brenda

Bos taurus

-

704402

Q0V8R6

UniProt

brenda

Bos taurus

-

707729

-

-

brenda

Bos taurus

calf

136607

-

-

brenda

Canavalia ensiformis

-

680303

-

-

brenda

Canavalia ensiformis

Jack bean

393678

-

-

brenda

Capsicum annuum

member of glycosyl hydrolase family 20

715769

E7BYE4

UniProt

brenda

Capsicum annuum

var. variata

656947

-

-

brenda

Coccidioides posadasii

CpHEX1; gene CpHEX1

709807

Q309C3

UniProt

brenda

Coccidioides posadasii

CpHEX2; gene CpHEX2

709807

A7XUU4

UniProt

brenda

Coccidioides posadasii Silveira

CpHEX1; gene CpHEX1

709807

Q309C3

UniProt

brenda

Coccidioides posadasii Silveira

CpHEX2; gene CpHEX2

709807

A7XUU4

UniProt

brenda

Homo sapiens

-

393653, 393658, 393677, 393693, 393700, 393701, 393702, 393721, 654853

-

-

brenda

Homo sapiens

-

656513

P07686

Uniprot

brenda

Homo sapiens

-

656520, 666083, 677298

-

-

brenda

Homo sapiens

-

677694

P07686

Uniprot

brenda

Homo sapiens

-

679170, 679259, 679260, 679277, 679278, 679279, 679301, 679785, 680166, 695422, 696118, 697342, 697367, 698154, 704414, 706030, 749904, 750051, 751214, 751281

-

-

brenda

Homo sapiens

healthy persons and mucolipidosis patients

393664

-

-

brenda

Homo sapiens

inhibition assay of human beta-N-acetyglucosaminidase by an analogue of 6-epi-valienamine

682225

-

-

brenda

Homo sapiens

isozyme Hex B

708101

-

-

brenda

Homo sapiens

newborns

393691

-

-

brenda

Homo sapiens

patient with GM2-gangliosidosis B1 variant

393680

-

-

brenda

Homo sapiens

patient with Sandhoffs disease

393668

-

-

brenda

Homo sapiens

patients with GM2-gangliosidosis B1 variant from the north of Portugal

393689

-

-

brenda

Homo sapiens

patients with I-cell disease and healthy persons

393694

-

-

brenda

Homo sapiens

patients with Tay-Sachs-disease

393690

-

-

brenda

Homo sapiens

pregnant women

393726

-

-

brenda

Mus musculus

-

666121, 682592

-

-

brenda

Mus musculus

-

696118

Q3U4H6

UniProt

brenda

Oryctolagus cuniculus

-

393667, 679688

-

-

brenda

Oryctolagus cuniculus

New Zealand white rabbit

665063

-

-

brenda

Ostrinia furnacalis

-

697881, 715645, 750049

Q06GJ0

UniProt

brenda

Ostrinia furnacalis

-

750050

-

-

brenda

Ostrinia furnacalis

-

750051

Q06GJ0

UniProt

brenda

Ostrinia furnacalis

glycosyl hydrolase family 20

714736

-

-

brenda

Penicillium oxalicum

-

664773, 714981, 715126

-

-

brenda

Penicillium oxalicum

IFO 5748

393660

-

-

brenda

Penicillium oxalicum

strains CCF1959, CCF2315 and CCF2430

697320

-

-

brenda

Rattus norvegicus

-

136606, 136607, 393670, 393688, 654795

-

-

brenda

Rattus norvegicus

rat

665199

-

-

brenda

Streptomyces plicatus

-

655992, 696619

-

-

brenda

Streptomyces plicatus

glycosyl hydrolase family 20

714736

O85361

UniProt

brenda

Streptomyces sp.

-

393703

-

-

brenda

Streptomyces sp.

ATCC 27800

393728

-

-

brenda

Streptomyces sp.

S. plicatus

393684, 393728

-

-

brenda

Talaromyces flavus

-

715126, 750184

-

-

brenda

Talaromyces flavus

strains CCF2573 and CCF2686

697320

-

-

brenda

Trametes cinnabarina

-

393484

-

-

brenda

Trametes cinnabarina

IFO 6139

393666

-

-

brenda

Trichoderma harzianum

-

393683, 664773, 697320

-

-

brenda

Trichoderma harzianum

isolate 1051

654313

-

-

brenda

Trichoderma harzianum

precursor, EXC1Y

655285

Q8NIN7

SwissProt

brenda

Trichoderma harzianum

precursor, EXC2Y

655285

Q8NIN6

SwissProt

brenda