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Information on EC 3.2.1.22 - alpha-galactosidase
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3.2.1.22 alpha-galactosidaseIUBMB Comments
Also hydrolyses alpha-D-fucosides.
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Word Map
- 3.2.1.22
- fabry
- lysosomal
-
x-linked
-
glycosphingolipids
-
globotriaosylceramide
- pain
- oligosaccharide
- galactose
- raffinose
- ventricular
- melibiose
- angiokeratomas
- cerebrovascular
-
inborn
- beta-glucosidase
- hypertrophy
-
glycolipids
- proteinuria
- glycosidases
-
anti-gal
-
xenotransplantation
-
galactomannans
-
xenoantigens
- alpha-n-acetylgalactosaminidase
- coffee
- guar
-
multisystemic
- stachyose
-
hyperacute
-
hemizygotes
- simplicifolia
- beta-d-galactosidase
-
bandeiraea
- beta-mannosidase
-
mortierella
- alpha-d-glucosidase
- analysis
- medicine
- alpha-fucosidase
- synthesis
-
endomyocardial
-
verticillata
- nutrition
- arylamidase
- biotechnology
- beta-hexosaminidase
- alpha-d-mannosidase
- griffonia
- degradation
- beta-xylosidase
- molecular biology
- beta-d-glucuronidase
- beta-mannanase
-
decellularization
-
isolectin
-
xenogeneic
-
flatulence
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
1,6-alpha-D-galactoside galactohydrolase, a-galactosidase, Aga-F78, Aga-Y, AgaA, agaAJB13, AgaB, AgaI, AGal, AgalB, 
more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
1,6-alpha-D-galactoside galactohydrolase
Aga-F78
agaAJB13
Agalsidase alfa
AglC
alkaline alpha-galactosidase
alpha-D-galactopyranoside galactohydrolase
alpha-D-galactosidase
Alpha-D-galactoside galactohydrolase
alpha-Gal
alpha-Gal A
alpha-galactosidase
alpha-galactosidase A
alpha-galactoside galactohydrolase
alphaGal1
Gal36
GalS
GLA
MelA
melibiase
TM1192
TmGalA
TnGalA
Agalsidase alfa
-
-
-
-
alpha-D-galactosidase
-
-
-
-
Alpha-D-galactoside galactohydrolase
-
-
-
-
alpha-galactosidase A
-
-
-
-
alpha-galactoside galactohydrolase
-
-
-
-
melibiase
-
-
-
-
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids
Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids
also hydrolyses alpha-D-fucosides
-
-
-
Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids
the recombinant enzyme catalyzes the hydrolysis of phenyl R-galactosides via a redox elimination-addition mechanism involving oxidation of the hydroxyl group at C-3 and elimination of phenol across the C-1-C-2 bond to give an enzyme-bound glycal intermediate
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hydrolysis of O-glycosyl bond
-
-
-
-
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PATHWAY SOURCE
PATHWAYS
BRENDA
KEGG
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SYSTEMATIC NAME
IUBMB Comments
alpha-D-galactoside galactohydrolase
Also hydrolyses alpha-D-fucosides.
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CAS REGISTRY NUMBER
COMMENTARY
9025-35-8
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1-naphthyl alpha-D-galactoside + H2O
1-naphthol + D-galactose
-
-
-
?
2,4,6-trinitrophenyl 2-deoxy-2,2-difluoro-alpha-D-galactopyranoside + H2O
2',4',6'-trinitrophenol + 2-deoxy-2,2-difluoro-alpha-D-galactopyranose
-
-
-
?
2,4-dinitrophenyl alpha-D-galactoside + H2O
2,4-dinitrophenol + alpha-D-galactose
O33835
-
-
-
-
2,5-dinitrophenyl alpha-D-galactoside + H2O
2,5-dinitrophenol + alpha-D-galactose
O33835
-
-
-
-
2-nitrophenyl alpha-D-galactopyranoside + H2O
2-nitrophenol + alpha-D-galactose
-
-
-
?
2-nitrophenyl alpha-D-galactopyranoside + H2O
2-nitrophenol + D-galactopyranose
-
16.5% of the activity with 4-nitrophenyl-alpha-D-galactopyranoside
-
?
3,4-dimethylphenyl alpha-D-galactoside + H2O
3,4-dimethylphenol + alpha-D-galactose
O33835
-
-
-
-
3-nitrophenyl alpha-D-galactoside + H2O
3-nitrophenol + alpha-D-galactose
O33835
-
-
-
-
3-nitrophenyl-alpha-D-galactopyranoside + H2O
3-nitrophenol + D-galactopyranose
-
5.6% of the activity with 4-nitrophenyl-alpha-D-galactopyranoside
-
?
4-bromophenyl alpha-D-galactoside + H2O
4-bromophenol + alpha-D-galactose
O33835
-
-
-
-
4-methoxyphenyl alpha-D-galactoside + H2O
4-methoxyphenol + alpha-D-galactose
O33835
-
-
-
-
4-methylumbelliferyl alpha-D-galactoside + H2O
alpha-D-galactose + 4-methylumbelliferone
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + D-galactose
-
-
-
?
4-nitrophenyl alpha-D-glucopyranoside + H2O
4-nitrophenol + D-glucose
-
-
-
-
?
4-nitrophenyl alpha-D-xylopyranoside + H2O
4-nitrophenol + alpha-D-xylopyranose
-
9.64% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
4-nitrophenyl beta-D-galactopyranoside + H2O
4-nitrophenol + beta-D-galactopyranose
low activity
-
-
?
4-O-[4-O-(6-O-alpha-D-galactopyranosyl-beta-D-mannopyranosyl)-beta-D-mannpyranosyl]-beta-D-mannose + H2O
alpha-D-galactopyranose + 4-O-[4-O-beta-D-mannopyranosyl-beta-D-mannpyranosyl]-beta-D-mannose
4-O-[4-O[4-O-(6-O-alpha-D-galactopyranosyl-beta-D-mannopyranosyl)-beta-D-mannpyranosyl]beta-D-mannopyranosyl]-beta-D-mannose + H2O
alpha-D-galactopyranose + 4-O-[4-O[4-O-beta-D-mannopyranosyl-beta-D-mannpyranosyl]beta-D-mannopyranosyl]-beta-D-mannose
-
-
-
-
?
6-bromo-2-naphthyl alpha-D-galactoside + H2O
6-bromo-2-naphthol + D-galactose
-
-
-
-
?
6-bromo-2-naphthyl alpha-D-galactoside + H2O
6-bromo-2-naphthol + D-glucose
-
-
-
?
alpha-D-galactopyranosyl-(1-6)-O-beta-D-mannopyranosyl-(1-4)-D-mannopyranosyl-(1-4)-D-mannopyranose + H2O
alpha-D-galactose + beta-D-mannopyranosyl-(1-4)-D-mannopyranosyl-(1-4)-D-mannopyranose
-
-
-
?
alpha-D-galactosyl fluoride + H2O
D-galactose + fluoride
-
-
-
?
beta-naphthyl alpha-D-galactoside + H2O
beta-naphthol + alpha-D-galactose
O33835
-
-
-
-
digalactosyldiacylglycerol + H2O
?
-
galactolipid substrate, located in chloroplast thylakoid membranes, converted by the purified recombinant cutinase (EC 3.1.1.74) expressed in tobacco chloroplasts and showing alpha galactosidase activity, EC 3.2.1.22
-
-
?
gentibiose-alternansucrase-derived oligosaccharide + ?
?
-
1.28fold increased activity compared to gentibiose
-
-
?
globotriaosylceramide + H2O
D-Galalpha(1,4)D-Glu-ceramide + D-galactose
-
i.e. D-Galalpha(1,4)D-Galalpha(1,4)D-Glu-ceramide
-
-
?
malitol-alternansucrase-derived oligosaccharide + ?
?
-
2.66fold increased activity compared to malitol
-
-
?
maltose-alternansucrase-derived oligosaccharide + ?
?
-
3.19fold increased activity compared to maltose
-
-
?
melibiose-alternansucrase-derived oligosaccharide + ?
?
-
1.45fold decreased activity compared to melibiose
-
-
?
N-acetyl-D-galactosamine + melibiose
6-O-alpha-D-galactosyl-N-acetyl-D-galactosamine + D-glucose
-
-
-
-
?
N-acetyl-D-glucosamine + melibiose
6-O-alpha-D-galactosyl-N-acetyl-D-glucosamine + H2O
-
-
-
-
?
O-beta-D-mannopyranosyl-(1-4)-O-[alpha-D-galactopyranosyl-(1-6)]-O-beta-D-mannopyranosyl-(1-4)-D-mannopyranosyl-(1-4)-D-mannopyranose + H2O
?
-
-
-
?
o-nitrophenyl alpha-D-galactopyranoside + H2O
o-nitrophenol + D-galactose
-
27.6% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
o-nitrophenyl beta-D-galactopyranoside
o-nitrophenol + beta-D-galactopyranose
-
4.53% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
o-nitrophenyl-beta-D-galactopyranose + H2O
o-nitrophenol + beta-D-galactopyranose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + D-glucose
?
-
transglycosylation
-
-
?
p-nitrophenyl alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
100% activity
-
-
?
p-nitrophenyl beta-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
enzyme P1: 5.5% of the activity with p-nitrophenyl alpha-D-galactopyranoside. Enzyme P2: no activity
-
-
?
p-nitrophenyl-beta-L-arabinopyranoside + H2O
p-nitrophenol + beta-L-arabinose
-
-
-
?
phenyl alpha-D-galactoside + H2O
phenol + alpha-D-galactose
O33835
-
-
-
-
raffinose-alternansucrase-derived oligosaccharide + ?
?
-
1.67fold increased activity compared to raffinose
-
-
?
2-nitrophenyl alpha-D-galactoside + H2O
2-nitrophenol + alpha-D-galactose
-
-
-
-
?
2-nitrophenyl alpha-D-galactoside + H2O
2-nitrophenol + alpha-D-galactose
O33835
-
-
-
-
4-methylumbelliferyl alpha-D-galactoside + H2O
4-methylumbelliferone + alpha-D-galactose
-
-
-
-
?
4-methylumbelliferyl alpha-D-galactoside + H2O
4-methylumbelliferone + alpha-D-galactose
-
-
-
-
?
4-methylumbelliferyl alpha-D-galactoside + H2O
4-methylumbelliferone + alpha-D-galactose
-
-
-
-
?
4-methylumbelliferyl alpha-D-galactoside + H2O
4-methylumbelliferone + D-galactose
-
-
-
-
?
4-methylumbelliferyl alpha-D-galactoside + H2O
4-methylumbelliferone + D-galactose
-
-
-
-
-
4-methylumbelliferyl alpha-D-galactoside + H2O
4-methylumbelliferone + D-galactose
-
-
-
-
?
4-methylumbelliferyl-alpha-D-galactoside + H2O
4-methylumbelliferol + alpha-D-galactose
-
-
-
-
-
4-methylumbelliferyl-alpha-D-galactoside + H2O
4-methylumbelliferol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
highest activity
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
M4GRS1
best substrate
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
M4GRS1
best substrate
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactose
H8Y263
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactose
H8Y263
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactose
G2RGW4
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactose
G2RGW4
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
-
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
hydrolysis is accompanied by transglycosylation resulting in production of a mixture of (alpha1,2)-, (alpha1,3)-, and (alpha1,6)-4-nitrophenyl-digalactosides
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
hydrolysis is accompanied by transglycosylation resulting in production of a mixture of (alpha1,2)-, (alpha1,3)-, and (alpha1,6)-4-nitrophenyl-digalactosides
-
-
?
4-nitrophenyl alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
Tachigali multijuga
-
-
-
-
?
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
O33835
-
-
-
-
4-nitrophenyl alpha-D-galactoside + H2O
4-nitrophenol + alpha-D-galactose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
Bispora sp.
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
Q7WWP9
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
activity measured in total fly homogenates, substrate concentration of 60 mM in citrate buffer
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + alpha-D-galactopyranose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
extracellular enzyme
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
intracellular enzyme
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
extracellular enzyme
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
intracellular enzyme
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
C6FJG8
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
C6FJG8
-
-
-
?
4-nitrophenyl-alpha-D-galactopyranoside + H2O
4-nitrophenol + D-galactopyranose
-
-
-
?
4-O-[4-O-(6-O-alpha-D-galactopyranosyl-beta-D-mannopyranosyl)-beta-D-mannpyranosyl]-beta-D-mannose + H2O
alpha-D-galactopyranose + 4-O-[4-O-beta-D-mannopyranosyl-beta-D-mannpyranosyl]-beta-D-mannose
-
-
-
-
?
4-O-[4-O-(6-O-alpha-D-galactopyranosyl-beta-D-mannopyranosyl)-beta-D-mannpyranosyl]-beta-D-mannose + H2O
alpha-D-galactopyranose + 4-O-[4-O-beta-D-mannopyranosyl-beta-D-mannpyranosyl]-beta-D-mannose
-
-
-
?
6(1)-alpha-D-galactosyl mannobiose + H2O
?
2.6% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
6(1)-alpha-D-galactosyl mannobiose + H2O
?
6.8% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
6(1)-alpha-D-galactosyl mannotriose + H2O
?
2.7% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
6(1)-alpha-D-galactosyl mannotriose + H2O
?
6.9% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
6(3),6(4)-di-alpha-D-galactosyl mannopentaose + H2O
?
0.5% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
6(3),6(4)-di-alpha-D-galactosyl mannopentaose + H2O
?
7.3% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
6-bromo-2-naphthyl-alpha-D-galactopyranoside + H2O
6-bromo-2-naphthol + D-galactose
C6FJG8
-
-
-
?
6-bromo-2-naphthyl-alpha-D-galactopyranoside + H2O
6-bromo-2-naphthol + D-galactose
C6FJG8
-
-
-
?
D-sucrose + H2O
D-glucose + D-fructose
-
35.71% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
D-sucrose + H2O
D-glucose + D-fructose
-
-
-
-
?
D-sucrose + H2O
D-glucose + D-fructose
-
16.30% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
galactomannan + H2O
?
-
with galactose/mannose ratios of 2.4 and of 1.72
-
-
?
guar gum + H2O
?
0.4% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
guar gum + H2O
?
1.7% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
lactose + H2O
beta-D-galactose + D-glucose
-
enzyme P1: 6.2% of the activity with p-nitrophenyl alpha-D-galactopyranoside. Enzyme P2: 1.3% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
lactose + H2O
beta-D-galactose + D-glucose
-
2.3% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
locust bean gum + H2O
?
0.4% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
locust bean gum + H2O
?
1.4% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
m-chlorophenyl alpha-D-galactoside + H2O
m-chlorophenol + D-galactose
-
-
-
-
?
maltose + H2O
alpha-D-glucose
-
6.07% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
maltose + H2O
alpha-D-glucose
-
enzyme P1: 4% of the activity with p-nitrophenyl alpha-D-galactopyranoside. Enzyme P2: 1.6% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
maltose + H2O
alpha-D-glucose
-
18.12% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
maltose + H2O
alpha-D-glucose
-
10.60% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
alpha-D-galactose + alpha-D-glucose
-
-
-
-
?
melibiose + H2O
alpha-D-galactose + alpha-D-glucose
H8Y263
5% of the activity with 4-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
alpha-D-galactose + alpha-D-glucose
H8Y263
5% of the activity with 4-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
alpha-D-galactose + D-glucose
-
42.1% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
alpha-D-galactose + D-glucose
-
enzyme P1: 6.9% of the activity with p-nitrophenyl alpha-D-galactopyranoside. Enzyme P2: 10% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
alpha-D-galactose + D-glucose
-
35.5% of Vmax with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
D-galactose + D-glucose
-
15.36% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
D-galactose + D-glucose
-
intracellular enzyme
-
-
?
melibiose + H2O
D-galactose + D-glucose
-
7.68% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
D-galactose + D-glucose
1.2% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
melibiose + H2O
D-galactose + D-glucose
6.9% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
melibiose + H2O
D-galactose + D-glucose
-
16.15% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
melibiose + H2O
D-galactose + D-glucose
-
negligible hydrolytic activity towards melibiose
-
-
?
melibiose + H2O
D-galactose + D-glucose
-
negligible hydrolytic activity towards melibiose
-
-
?
melibiose + H2O
D-galactose + D-glucose
-
7.3% of Vmax with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
o-nitrophenyl alpha-D-galactopyranoside + H2O
o-nitrophenol + alpha-D-galactose
-
-
-
-
?
o-nitrophenyl alpha-D-galactopyranoside + H2O
o-nitrophenol + alpha-D-galactose
-
-
-
-
?
o-nitrophenyl alpha-D-galactopyranoside + H2O
o-nitrophenol + alpha-D-galactose
-
-
-
-
?
o-nitrophenyl alpha-D-galactoside + H2O
o-nitrophenol + D-galactose
-
-
-
-
-
o-nitrophenyl alpha-D-galactoside + H2O
o-nitrophenol + D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
Absidia sp. (in: Fungi) WL511
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
100% activity
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
100% activity
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
100% activity
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + D-galactose
-
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + D-galactose
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
alpha-galactosidase 1
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
alpha-galactosidase 2
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
alpha-galactosidase 3
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
-
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
-
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
-
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
p-nitrophenyl-alpha-D-galactoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
phenyl alpha-D-galactoside + methanol
methyl alpha-D-galactoside + phenol
-
-
-
-
?
phenyl alpha-D-galactoside + methanol
methyl alpha-D-galactoside + phenol
Coffea sp.
-
-
-
-
?
phenyl alpha-D-galactoside + methanol
methyl alpha-D-galactoside + phenol
-
-
-
-
?
phenyl alpha-D-galactoside + methanol
methyl alpha-D-galactoside + phenol
-
-
-
-
?
phenyl alpha-D-galactoside + methanol
methyl alpha-D-galactoside + phenol
-
-
-
-
?
raffinose + H2O
D-galactose + sucrose
-
assay at pH 7.5, 37°C, 15 min, reaction terminated by 2 min boiling
-
-
?
raffinose + H2O
D-galactose + sucrose
-
assay at pH 7.5, 37°C, 20 min, reaction terminated by keeping the reaction mixture in boiling water for 2 min
-
-
?
raffinose + H2O
D-galactose + sucrose
H8Y263
13.5% of the activity with 4-nitrophenyl alpha-D-galactopyranoside
-
-
?
raffinose + H2O
D-galactose + sucrose
H8Y263
13.5% of the activity with 4-nitrophenyl alpha-D-galactopyranoside
-
-
?
raffinose + H2O
sucrose + alpha-D-galactose
-
52.4% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
raffinose + H2O
sucrose + alpha-D-galactose
-
enzyme P1: 11.8% of the activity with p-nitrophenyl alpha-D-galactopyranoside. Enzyme P2: 54.3% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
raffinose + H2O
sucrose + alpha-D-galactose
1.89% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
raffinose + H2O
sucrose + alpha-D-galactose
10.1% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
raffinose + H2O
sucrose + alpha-D-galactose
-
Vmax is 1.8fold higher than that with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
raffinose + H2O
sucrose + alpha-D-galactose
-
20% of the Vmax with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
raffinose + H2O
sucrose + D-galactose
-
78.57% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
raffinose + H2O
sucrose + D-galactose
-
-
-
-
?
raffinose + H2O
sucrose + D-galactose
-
intracellular enzyme
-
-
?
raffinose + H2O
sucrose + D-galactose
-
30.60% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
raffinose + H2O
sucrose + D-galactose
-
60.65% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
high actvity with alpha-Gal I, low activity with alpha-Gal II
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
85.71% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
-
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
-
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
69.7% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
-
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
enzyme P1: 5% of the activity with p-nitrophenyl alpha-D-galactopyranoside. Enzyme P2: 10.5% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
11.74% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
0.47% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
1.9% relative activity compared to p-nitrophenyl alpha-D-galactoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
78.65% activity relative to p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
Vmax is 2fold higher than that with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
17.8% of the Vmax with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
-
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
20fold less active than with raffinose
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
20fold less active than with raffinose
-
-
?
stachyose + H2O
raffinose + D-galactose
H8Y263
31% of the activity with 4-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + H2O
raffinose + D-galactose
H8Y263
31% of the activity with 4-nitrophenyl alpha-D-galactopyranoside
-
-
?
verbascose + H2O
alpha-D-galactose + alpha-D-glucopyranosyl-(1,2)-beta-D-fructofuranoside
-
-
-
-
?
verbascose + H2O
alpha-D-galactose + alpha-D-glucopyranosyl-(1,2)-beta-D-fructofuranoside
-
20fold less active than with raffinose
-
-
?
verbascose + H2O
alpha-D-galactose + alpha-D-glucopyranosyl-(1,2)-beta-D-fructofuranoside
-
-
-
-
?
additional information
?
-
-
pectin and polygalacturonic acid are not measurably degraded
-
-
-
additional information
?
-
-
D-lactose, o-nitrophenyl beta-D-galactopyranoside, p-nitrophenyl alpha-D-glucopyranoside, p-nitrophenyl alpha-D-mannopyranoside, and p-nitrophenyl beta-D-galactopyranoside are no substrates
-
-
-
additional information
?
-
-
when treated with the Bacillus megaterium VHM1 enzyme, the flatulence-causing sugars in soymilk are completely hydrolyzed within 1.5 h
-
-
-
additional information
?
-
-
activity is not enhanced on sucrose and beta-linked carbohydrates and fructooligosaccharides
-
-
-
additional information
?
-
-
under optimum pH conditions and high melibiose concentration of 40% w/v, the enzyme is able to form oligosaccharides with degree of polymerisation of 3 and more at higher concentration than with degree of polymerization 2, with a total yield of 20.5% w/w
-
-
-
additional information
?
-
under optimum pH conditions and high melibiose concentration of 40% w/v, the enzyme is able to form oligosaccharides with degree of polymerisation of 3 and more at higher concentration than with degree of polymerization 2, with a total yield of 20.5% w/w
-
-
-
additional information
?
-
-
raffinose induces about twice the activity than melibiose
-
-
-
additional information
?
-
enzyme additionally catalyzes transglycosylation. It is able to synthesize a trisaccharide galactose-(alpha-1,4)-galactose(alpha-1,6)-glucose using melibiose as substrate. In presence of 4-nitrophenyl-alpha-D-galactopyranoside, enzyme catalyzes glycosyl transfer to various acceptors
-
-
-
additional information
?
-
no substrate: 3-nitrophenyl-beta-D-galactopyranoside, 4-nitrophenyl-beta-D-galactopyranoside, 4-nitrophenyl-beta-D-galacturonide, 2-nitrophenyl-alpha-D-glucopyranoside, 2-nitrophenyl-beta-D-glucopyranoside, 4-nitrophenyl-alpha-L-fucopyranoside, 4-nitrophenyl-beta-D-fucopyranoside, 4-nitrophenyl-alpha-D-mannopyranoside, 4-nitrophenyl-beta-D-mannopyranoside, 4-nitrophenyl-2-(acetylamino)-2-deoxy-alpha-D-galactopyranoside, 4-nitrophenyl-2-(acetylamino)-2-deoxy-beta-D-galactopyranoside, and 2-nitrophenyl-2-(acetylamino)-2-deoxy-beta-D-galactopyranoside
-
-
-
additional information
?
-
-
raffinose induces about twice the activity than melibiose
-
-
-
additional information
?
-
-
activity with soy molasses
-
-
-
additional information
?
-
-
alpha-galactosidase 2 has the ability to markedly catalyze increased pectin solubility and depolymerization while the polymers are still structurally attached to the cell walls mimicking, in part, the changes that occur during ripening. The enzyme might contribute to papaya fruit softening during ripening
-
-
-
additional information
?
-
-
one of the principal enzymes involved in the modification or degradation of plant cell wall galactomannans
-
-
-
additional information
?
-
one of the principal enzymes involved in the modification or degradation of plant cell wall galactomannans
-
-
-
additional information
?
-
-
no detectable activity towards methyl-alpha-D-galactopyranoside, locust bean gum, guar gum, and alpha-D-Gal-(1,4)-D-Gal
-
-
-
additional information
?
-
-
no detectable activity towards methyl-alpha-D-galactopyranoside, locust bean gum, guar gum, and alpha-D-Gal-(1,4)-D-Gal
-
-
-
additional information
?
-
-
D-sucrose, p-nitrophenyl alpha-D-glucopyranoside, p-nitrophenyl alpha-D-xylulopyranoside, p-nitrophenyl alpha-D-mannopyranoside, and p-nitrophenyl beta-D-galactopyranoside are no substrates
-
-
-
additional information
?
-
-
Fabry disease is a X-linked inborn error of glycolipid metabolism caused by deficiency of the lysosomal enzyme alpha-galactosidase A
-
-
-
additional information
?
-
-
Fabry disease is a X-linked inborn error of glycolipid metabolism caused by deficiency of the lysosomal enzyme alpha-galactosidase A. This enzyme is responsible for the hydrolysis of terminal alpha-galactosidase linkages in various glycolipids
-
-
-
additional information
?
-
Fabry disease is an X-linked genetic disorder resulting from a deficiency of alpha-galactosidase activity
-
-
-
additional information
?
-
-
transcription is induced by melibiose but is not totally repressed by glucose
-
-
-
additional information
?
-
transcription is induced by melibiose but is not totally repressed by glucose
-
-
-
additional information
?
-
-
lactose, o-nitrophenyl beta-D-galactopyranoside, p-nitrophenyl alpha-D-xylulopyranoside, p-nitrophenyl alpha-D-mannopyranoside, and p-nitrophenyl beta-D-galactopyranoside are no substrates
-
-
-
additional information
?
-
-
enzyme displays a retentive, double-displacement mechanism. No detectable activity on the 4-nitrophenyl alpha-D-glucopyranoside or 4-nitrophenyl alpha-D-mannopyranoside
-
-
-
additional information
?
-
enzyme displays a retentive, double-displacement mechanism. No detectable activity on the 4-nitrophenyl alpha-D-glucopyranoside or 4-nitrophenyl alpha-D-mannopyranoside
-
-
-
additional information
?
-
shows no activity toward p-nitrophenyl-alpha-substituted hexoses such as D-glucose, D-mannose, L-rhamnose, or N-acetyl-D-galactosaminide, p-nitrophenyl-beta-substituted hexoses such as D-galactose, D-glucose, and D-mannose do not support catalysis, nor does the pentose p-nitrophenyl-beta-D-xylopyranoside
-
-
-
additional information
?
-
-
shows no activity toward p-nitrophenyl-alpha-substituted hexoses such as D-glucose, D-mannose, L-rhamnose, or N-acetyl-D-galactosaminide, p-nitrophenyl-beta-substituted hexoses such as D-galactose, D-glucose, and D-mannose do not support catalysis, nor does the pentose p-nitrophenyl-beta-D-xylopyranoside
-
-
-
additional information
?
-
shows no activity toward p-nitrophenyl-alpha-substituted hexoses such as D-glucose, D-mannose, L-rhamnose, or N-acetyl-D-galactosaminide, p-nitrophenyl-beta-substituted hexoses such as D-galactose, D-glucose, and D-mannose do not support catalysis, nor does the pentose p-nitrophenyl-beta-D-xylopyranoside
-
-
-
additional information
?
-
O33835
no detectable enzymatic activity on xylo-, fuco-, manno-, or glucopyranosides
-
-
-
additional information
?
-
-
slight preference for branched galactosyl residues over straight chain residues
-
-
-
additional information
?
-
-
slight preference for branched galactosyl residues over straight chain residues
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
globotriaosylceramide + H2O
D-Galalpha(1,4)D-Glu-ceramide + D-galactose
-
i.e. D-Galalpha(1,4)D-Galalpha(1,4)D-Glu-ceramide
-
-
?
melibiose + H2O
alpha-D-galactose + D-glucose
-
42.1% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
o-nitrophenyl alpha-D-galactopyranoside + H2O
o-nitrophenol + D-galactose
-
27.6% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + D-glucose
?
-
transglycosylation
-
-
?
p-nitrophenyl alpha-D-galactopyranoside + H2O
p-nitrophenol + alpha-D-galactose
-
-
-
-
?
raffinose + H2O
sucrose + alpha-D-galactose
-
52.4% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
stachyose + 2 H2O
2 alpha-D-galactose + sucrose
-
69.7% of the activity with p-nitrophenyl alpha-D-galactopyranoside
-
-
?
additional information
?
-
-
when treated with the Bacillus megaterium VHM1 enzyme, the flatulence-causing sugars in soymilk are completely hydrolyzed within 1.5 h
-
-
-
additional information
?
-
-
raffinose induces about twice the activity than melibiose
-
-
-
additional information
?
-
-
raffinose induces about twice the activity than melibiose
-
-
-
additional information
?
-
-
alpha-galactosidase 2 has the ability to markedly catalyze increased pectin solubility and depolymerization while the polymers are still structurally attached to the cell walls mimicking, in part, the changes that occur during ripening. The enzyme might contribute to papaya fruit softening during ripening
-
-
-
additional information
?
-
-
one of the principal enzymes involved in the modification or degradation of plant cell wall galactomannans
-
-
-
additional information
?
-
Q5DUH7
one of the principal enzymes involved in the modification or degradation of plant cell wall galactomannans
-
-
-
additional information
?
-
-
Fabry disease is a X-linked inborn error of glycolipid metabolism caused by deficiency of the lysosomal enzyme alpha-galactosidase A
-
-
-
additional information
?
-
-
Fabry disease is a X-linked inborn error of glycolipid metabolism caused by deficiency of the lysosomal enzyme alpha-galactosidase A. This enzyme is responsible for the hydrolysis of terminal alpha-galactosidase linkages in various glycolipids
-
-
-
additional information
?
-
P06280
Fabry disease is an X-linked genetic disorder resulting from a deficiency of alpha-galactosidase activity
-
-
-
additional information
?
-
-
transcription is induced by melibiose but is not totally repressed by glucose
-
-
-
additional information
?
-
Q9L905
transcription is induced by melibiose but is not totally repressed by glucose
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Ag+
Ca2+
Co2+
Cr3+
the activity of recombinant Aga-F78 is significantly enhanced in the presence of Cr3+
Cu2+
EDTA
Fe2+
Fe3+
the activity of recombinant Aga-F78 is significantly enhanced in the presence of Fe3+
Hg2+
K+
Mg2+
Mn2+
Na+
Ni2+
Pb2+
Zn2+
additional information
Pb2+
the activity of recombinant Aga-F78 is significantly enhanced in the presence of Pb2+
additional information
-
Ba2+, Ca2+, Co2+, Fe3+, K+, Mg2+, Mn2+, Na+, Ni2+, Zn2+ (1 mM) and EDTA (10 mM) have no influence on enzyme activity