3.4.11.1: leucyl aminopeptidase

This is an abbreviated version!
For detailed information about leucyl aminopeptidase, go to the full flat file.

Word Map on EC 3.4.11.1

3.4.11.1

aminopeptidases

border

brush

bestatin

transpeptidase

gamma-glutamyl

maltase

carboxypeptidase

sucrase

urinary

pregnancy

bile

urine

esterase

mucosa

trim

chymotrypsin

transaminase

dipeptidyl

beta-glucuronidase

5'-nucleotidase

exopeptidase

brush-border

histocompatibility

bilirubin

nephrotoxicity

gamma-glutamyltransferase

alanyl

ankylosing

spondylitis

arylamidase

jaundice

p-nitroanilide

canalicular

hepatobiliary

n-acetyl-beta-glucosaminidase

gamma-glutamyltranspeptidase

dipeptidase

disaccharidase

oxytocinase

gamma-gtp

cholinesterase

3.4.11.2

amastatin

trehalase

hepatica

cellobiohydrolase

peptidome

fasciola

enzymuria

medicine

synthesis

pharmacology

food industry

drug development

diagnostics

Reaction

release of an N-terminal amino acid, Xaa-/-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolysed, but rates on arylamides are exceedingly low =

Synonyms

A-LAP, acidic M17 leucine aminopeptidase, AcLAP, adipocyte-derived leucine aminopeptidase, Aminopeptidase, aminopeptidase A, Aminopeptidase A/I, aminopeptidase I, aminopeptidase II, Aminopeptidase III, aminopeptidase LAP2, aminopeptidase N, AP 28, AP 56, APDkam589, APN, b/LAP, bovine lens/leucine aminopeptidase, BSAP, cathepsin III, CsLAP1, CsLAP2, cysteinyl-glycine hydrolysing activity, cysteinylglycine-hydrolysing activity, cytosol aminopeptidase, DR57, EC 3.4.1.1, Eg-LAP, endoplasmic reticulum aminopeptidase, ER-aminopeptidase-1, ERAP, ERAP1, ERAP2, FgLAP, FrvX, FTBL protein, FTBL proteins, HSA, L-leucine aminopeptidase, la, LAP, LAP yspII, LAP-A, LAP-N, LAP1, LAP2, lap3, LapA, LAPc, LeuAP, leucinamide aminopeptidase, leucinaminopeptidase, leucine amino peptidase, leucine aminopeptidase, leucine aminopeptidase 1, leucine aminopeptidase 2, leucine aminopeptidase 3, leucine aminopeptidase A, leucine aminopeptidase LAP-N, leucine aminopeptidase N, leucine aminopeptidase,, leucine aminopeptidase-A, Leucyl aminopeptidase, leucyl aminopeptidase (animal), leucyl aminopeptidase (plant), leucyl aminopeptidase yspII, leucyl peptidase, leucylaminopeptidase, leucylpeptidase, LmLAP-A, M17 family leucyl aminopeptidase metalloprotease, M17 LAP, M17 leucine amino peptidase, M17 leucine aminopeptidase, M17 leucyl aminopeptidase, M42 aminopeptidase, major leucyl aminopeptidase, More, PA2939, PaAP, PepA, PepA peptidase A, PepB, peptidase B, peptidase II, peptidase S, pepZ, PfLAP, PH1527, PhTET2, PILS-AP, PILSAP, Placental leucine aminopeptidase, PLAP, proline aminopeptidase, Prolyl aminopeptidase, proteins, specific or class, FTBL, PtLAP, puromycin insensitive leucyl-specific aminopeptidase, puromycin-insensitive leucine specific aminopeptidase, puromycin-insensitive leucyl-specific aminopeptidase, PVX_118180, rLAP, rMHJ_0461, S-Lap1, S-Lap2, S-Lap3, S-Lap4, S-Lap5, S-Lap6, S-Lap7, S-Lap8, SmLAP1, SmLAP2, Smp_03000, Smp_083870, sperm-leucylaminopeptidase, TbLAP-A, TbLAP1, TcLAP-A, TM0042, TpLAP, XoLAP

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.11 Aminopeptidases

3.4.11.1 leucyl aminopeptidase

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Results	in table
14	Activating Compound
30968	AA Sequence
24	Application
2	CAS Registry Number
70	Cloned(Commentary)
17	Crystallization (Commentary)
1272	Disease/ Diagnostics
16	Expression
91	General Information
7	General Stability
117	IC50 Value
601	Inhibitors
58	kcat/KM [mM/s]
39	Ki Value [mM]
197	KM Value [mM]
87	Localization
279	Metals/Ions
124	Molecular Weight [Da]
51	Natural Substrates/ Products (Substrates)
10	Organic Solvent Stability
623	Organism
2	Pathway
240	PDB ID
124	pH Optimum
30	pH Range
20	pH Stability
9	pI Value
7	Posttranslational Modification
88	Protein Variants
98	Purification (Commentary)
20	Reaction
6	Reaction Type
247	Reference
1	Renatured (Commentary)
288	Source Tissue
148	Specific Activity [micromol/min/mg]
17	Storage Stability
707	Substrates and Products (Substrate)
99	Subunits
410	Synonyms
77	Temperature Optimum [°C]
10	Temperature Range [°C]
54	Temperature Stability [°C]
151	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.11.1 - leucyl aminopeptidase

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A-LAP