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Literature summary for 3.4.11.1 extracted from

  • Pokharel, D.R.; Rai, R.; Kumar, P.; Chaturvedi, C.M.; Rathaur, S.
    Tissue localization of collagenase and leucine aminopeptidase in the bovine filarial parasite Setaria cervi (2006), Filaria J., 5, DOI:10.1186/1475-2883-5-7.
No PubMed abstract available
Search for more literature for 3.4.11.1

Application

Application Comment Organism
diagnostics the enzyme might be a good diagnostic marker Setaria cervi
medicine the enzyme is a candidate for vaccine production Setaria cervi

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
 Setaria cervi
amastatin
-
 Setaria cervi
bestatin
-
 Setaria cervi
EDTA
-
 Setaria cervi

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc-metallopeptidase Setaria cervi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Setaria cervi the enzyme probably is involved in fertility and parasite survival ?
-
 ?

Organism

Organism UniProt Comment Textmining
Setaria cervi
-
 filarial parasite worm, from peritoneal folds of Indian buffalo
-

Source Tissue

Source Tissue Comment Organism Textmining
egg mature Setaria cervi
-
embryo
-
 Setaria cervi
-
endodermis
-
 Setaria cervi
-
intestine
-
 Setaria cervi
-
additional information tissue distribution of the enzyme inside the worm, overview, the enzyme is nearly absent in syncytial hypodermis and nerve cord region Setaria cervi
-
muscle epicuticle, longitudinal muscle layer Setaria cervi
-
ovary germinalzone Setaria cervi
-
uterus uterine wall Setaria cervi
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Leu-4-nitroanilide + H2O
-
 Setaria cervi L-Leu + 4-nitroaniline
-
 ?
additional information the enzyme probably is involved in fertility and parasite survival Setaria cervi ?
-
 ?

Synonyms

Synonyms Comment Organism
LAP
-
 Setaria cervi
leucine aminopeptidase
-
 Setaria cervi
More the enzyme belongs to the M17 aminopeptidase family Setaria cervi