Reference on EC 3.4.11.1 - leucyl aminopeptidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ogata, K.; Ohno, R.; Morioka, S.; Terao, K.
Further study on association of 5SrRNA-L5 protein complex and methionyl-tRNA to methionyl-tRNA synthetase in the macromolecular aminoacyl-tRNA synthetase complex
J. Biochem.
120
869-880
1996
Bos taurus
Delange, R.J.; Smith, E.L.
Leucine aminopeptidase and other N-terminal exopeptidases
The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbck, K. , eds. )
3
81-118
1971
Bos taurus, Sus scrofa
-
Appel, W.
Aminopeptidasen und Aminosaeurearylamidasen
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
1
987-1015
1974
Bos taurus, Brassica sp., Oryctolagus cuniculus, Homo sapiens, Proteus vulgaris, Rattus norvegicus, Sus scrofa, trout
-
Prescott, J.M.; Wilkes, S.H.
Aeromonas aminopeptidase
Methods Enzymol.
45
530-543
1976
Vibrio proteolyticus
Ichishima, E.; Yamagata, Y.; Chiba, H.; Sawaguchi, K.; Tanaka, T.
Soluble and bound forms of aminopeptidase in hen's egg yolk
Agric. Biol. Chem.
53
1867-1872
1989
Gallus gallus
-
Ludewig, M.; Fricke, B.; Aurich, H.
Leucine aminopeptidase in intracytoplasmic membranes of Acinetobacter calcoaceticus
J. Basic Microbiol.
27
557-563
1987
Acinetobacter calcoaceticus
Lauffart, B.; McDermott, J.; Gibson, A.; Mantle, D.
Purification and characterization of leucine aminopeptidase from human cerebral cortex
Biochem. Soc. Trans.
16
850-851
1988
Homo sapiens
-
Lynn, K.R.; Clevette-Radfort, N.A.
Biochemical properties of latices from the euphorbiaceae
Phytochemistry
26
939-944
1987
Euphorbiaceae
-
Conlan, J.W.; Baskerville, A.; Ashworth, L.A.E.
Separation of Legionella pneumophila proteases and purification of a protease which produces lesions like those of Legionnaires' disease in guinea pig lung
J. Gen. Microbiol.
132
1565-1574
1986
Legionella pneumophila
Kohno, H.; Kanda, S.; Kanno, T.
Immunoaffininty purification and characterization of leucine aminopeptidase from human liver
J. Biol. Chem.
61
10744-10748
1986
Homo sapiens
Vitale, L.; Renko, M.; Lenarcic, B.; Turk, V.; Pokorny, M.
Streptomyces rimosus extracellular proteases
Appl. Microbiol. Biotechnol.
23
449-455
1986
Streptomyces rimosus
-
Oettgen, H.C.; Taylor, A.
Purification, preliminary characterization, and immunological comparison of hog lens leucine aminopeptidase (EC 3.4.11.1) with hog kidney and beef lens aminopeptidase
Anal. Biochem.
146
238-245
1985
Sus scrofa
Kohno, H.; Kanno, T.
Properties and activities of aminopeptidases in normal and mitogen-stimulated human lymphocytes
Biochem. J.
226
59-65
1985
Homo sapiens
Andersson, L.; MacNeela, J.; Wolfenden, R.
Use of secondary isotope effects and varying pH to investigate the mode of binding of inhibitory aldehydes by leucine aminopeptidase
Biochemistry
24
330-333
1985
Sus scrofa
Taylor, A.; Volz, K.W.; Lipscomb, W.N.; Takemoto, L.J.
Leucine aminopeptidase from bovine lens and hog kidney
J. Biol. Chem.
259
14757-14761
1984
Sus scrofa
Harris, C.A.; Hunte, B.; Krauss, M.R.; Taylor, A.; Epstein, L.B.
Induction of leucine aminopeptidase by interferon-gamma
J. Biol. Chem.
267
6865-6869
1992
Homo sapiens
Machuga, E.J.; Ives, D.H.
Isolation and characterization of an aminopeptidase from Lactobacillus acidophilus
Biochim. Biophys. Acta
789
26-36
1984
Lactobacillus acidophilus
Taylor, A.; Sawan, S.; James, T.L.
Structural aspects of the inhibitor complex formed by N-(leucyl)-o-aminobenzenesulfonate and manganese with Zn2+-Mn2+ leucine aminopeptidase (EC 3.4.11.1)
J. Biol. Chem.
257
11571-11576
1982
Bos taurus
Taylor, A.; Tisdell, F.E.; Carpenter, F.H.
Leucine aminopeptidase (bovine lense): Synthesis and kinetic properties of ortho-, meta-, and para-substituted leucyl-anilides
Arch. Biochem. Biophys.
210
90-97
1981
Bos taurus
Ledeme, N.; Hennon, G.; Vincent-Fiquet, O.; Plaquet, R.
Purification and enzymatic properties of an L-leucine aminopeptidase from swine liver
Biochim. Biophys. Acta
660
262-270
1981
Sus scrofa
Van Loon-Klaassen, L.A.H.; Cuypers, H.T.; van Westreenen, H.; de Jong, W.W.; Bloemendal, H.
The primary stucture of bovine lens leucine aminopeptidase
Biochem. Biophys. Res. Commun.
95
334-341
1980
Bos taurus
Wiersma, M.; Versteegh, G.; Assink, H.A.; Welling, G.W.; Harder, W.
Purification and some properties of two extracellular proteolytic enzymes produced by Vibrio SA1
Antonie van Leeuwenhoek
44
157-169
1978
Vibrio sp., Vibrio sp. SA1
Foissy, H.
Some properties of aminopeptidase from Brevibacterium linens
FEMS Microbiol. Lett.
3
207-210
1978
Brevibacterium linens
-
Nakadai, T.; Nasuno, S.; Iguchi, N.
Purification and properties of leucine aminopeptidase I from Aspergillus oryzae
Agric. Biol. Chem.
37
757-765
1973
Aspergillus oryzae
-
Nakadai, T.; Nasuno, S.; Iguchi, N.
Purification and properties of leucine aminopeptidase II from Aspergillus oryzae
Agric. Biol. Chem.
37
767-774
1973
Aspergillus oryzae
-
Stuart, D.D.; Doughty, M.J.
In vitro UVB irradiation of bovine crystalline lens causes cell damage and reduction in leucine aminopeptidase activity in lens epithelium
J. Photochem. Photobiol. B, Biol.
32
81-87
1996
Bos taurus
Nakadai, T.; Nasuno, S.; Iguchi, N.
Purification and properties of aminopeptidase III from Aspergillus oryzae
Agric. Biol. Chem.
37
775-782
1973
Aspergillus oryzae
-
Nakadai, S.; Nasuno, S.
Purification and properties of leucine aminopeptidase IV from Aspergillus oryzae
Agric. Biol. Chem.
41
1657-1666
1977
Aspergillus oryzae
-
Hanson, H.; Frohne, M.
Crystalline leucine aminopeptidase from lens
Methods Enzymol.
45
504-521
1976
Bos taurus, Saccharomyces cerevisiae
Mikkonen, A.
Purification and characterization of leucine aminopeptidase from kidney bean cotyledons
Physiol. Plant.
84
393-398
1992
Bos taurus, Phaseolus vulgaris
-
Cherry, J.P.; Ory, R.L.
Electrophoretic characterization of six selected enzymes of peanut cultivars
Phytochemistry
12
283-289
1973
Arachis hypogaea
-
Jones, D.D.; Williams, G.; Prochazka, B.
Multiple molecular forms of enzymes hydrolyzing L-leucyl-beta-naphtylamide during gestation
Enzymologia
43
325-332
1972
Homo sapiens
-
Light, A.
Leucine aminopeptidase in sequence determination of peptides
Methods Enzymol.
25B
253-262
1972
Sus scrofa
-
Himmelhoch, S.R.
Leucine aminopeptidase from swine kidney
Methods Enzymol.
19
508-513
1970
Sus scrofa
-
Himmelhoch, S.R.
Leucine aminopeptidase: A zinc metalloenzyme
Arch. Biochem. Biophys.
134
597-602
1969
Sus scrofa
Hanson, H.; Glaesser, D.; Ludewig, M.; Mannfeldt, H.G.; John, M.; Nesvadba, H.
Struktur- und Wirkungsidentitaet der Leucinaminopeptidase aus Schweinenieren und Rinderaugenlinsen und Vergleich mit der Partikelaminopeptidase aus Schweinenieren
Hoppe-Seyler's Z. Physiol. Chem.
348
689-704
1967
Bos taurus, Sus scrofa
-
Kretschmer, K.; Hanson, H.
Kristallisierte Leucinaminopeptidase aus Rinderaugenlinsen
Hoppe-Seyler's Z. Physiol. Chem.
349
831-845
1968
Bos taurus
Kretschmer, K.
Kristallisierte Leucinaminopeptidase aus Rinderaugenlinsen
Hoppe-Seyler's Z. Physiol. Chem.
349
846-856
1968
Bos taurus
Hanson, H.; Glaesser, D.; Kirschke, H.
Leucinaminopeptidase aus Rinderaugenlinsen
Hoppe-Seyler's Z. Physiol. Chem.
340
107-125
1965
Bos taurus
-
Kretschmer, K.; Hanson, H.
Kristallisierte Leucinaminopeptidase aus Rinderaugenlinsen
Hoppe-Seyler's Z. Physiol. Chem.
340
126-137
1965
Bos taurus
-
Bartling, D.; Nosek, J.
Molecular and immunological characterization of leucine aminopeptidase in Arabidopsis thaliana: A new antibody suggests a semi-constitutive regulation of aphylogenetically old enzyme
Plant Sci.
9
199-209
1994
Arabidopsis thaliana
-
Kim, H.; Lipscomb, W.N.
X-ray crystallographic determination of the structure of bovine lens leucine aminopeptidase complexed with amastatin: Formulation of a catalytic mechanism featuring a gem-diolate transition state
Biochemistry
32
8465-8478
1993
Bos taurus
Straeter, N.; Lipscomb, W.N.
Two-metal ion mechanism of bovine lens leucine aminopeptidase: Active site solvent structure and binding mode of L-leucinal, a gem-diolate transition state analogue, by x-ray crystallography
Biochemistry
34
14792-14800
1995
Bos taurus
Gu, Y.Q.; Holzer, F.M.; Walling, L.
Overexpression, purification and biochemical characterization of the wound-induced leucine aminopeptidase of tomato
Eur. J. Biochem.
263
726-735
1999
Solanum lycopersicum
Kim, H.; Libscomb, W.N.
Differentiation and identification of the two catalytic metal binding sites in bovine lens leucine aminopeptidase by x-ray crystallography
Proc. Natl. Acad. Sci. USA
90
5006-5010
1993
Bos taurus
Burley, S.K.; David, P.R.; Lipscomb, W.N.
Leucine aminopeptidase: Bestatin inhibition and a model for enzyme-catalyzed peptide hydrolysis
Proc. Natl. Acad. Sci. USA
88
6916-6920
1991
Bos taurus
Kam, J.; Jaswal, V.M.S; Mahmmood, A.
Kinetic properties of gamma-glutamyltranspeptidase and leucineaminopeptidase in developing rat intestine: Effect of hormones
Indian J. Exp. Biol.
28
18-22
1990
Rattus norvegicus
Sankievicz, D.; Colepicolo, P.
A new member of the leucyl aminopeptidase family purified and identified from a marine unicellular algae
Biochem. Biophys. Res. Commun.
262
557-561
1999
Lingulodinium polyedra
Kumagai, Y.; Watanabe, Y.; Fujimoto, Y.
Purification and characterization of leucine-specific aminopeptidase from the soluble fraction of human placenta
Biochem. Med. Metab. Biol.
46
110-118
1991
Homo sapiens
Xu, Y.Z.; Shawar, S.M.; Dresden, M.H.
Schistosoma mansoni: Purification and characterization of a membrane-associated leucine aminopeptidase
Exp. Parasitol.
70
124-133
1990
Schistosoma mansoni
Acosta, D.; Goni, F.; Carmona, C.
Characterization and partial purification of a leucine aminopeptidase from Fasciola hepatica
J. Parasitol.
84
1-7
1998
Fasciola hepatica
Lee, G.D.; Chun, S.S.; Kho, Y.H.; Chun, H.K.
Purification and properties of an extracellular leucine aminopeptidase from the Bacillus sp. N2
J. Appl. Microbiol.
84
561-566
1998
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) N2
-
Gibson, A.M.; Biggins, J.A.; Lauffart, B.; Mantle, D.; McDermott, J.R.
Human brain leucyl aminopeptidase: Isolation, characterization and specificity against some neuropeptide
Neuropeptides
19
163-168
1991
Homo sapiens
Mathew, Z.; Knox, T.M.; Miller, C.G.
Salmonella enterica serovar Typhimurium peptidase B is a leucyl aminopeptidase with specificity for acidic amino acids
J. Bacteriol.
182
3383-3393
2000
Salmonella enterica (Q9RF52)
Cappiello, M.; Lazzarotti, A.; Buono, F.; Scaloni, A.; D'ambrosio, C.; Amodeo, P.; Mendez, B.L.; Pelosi, P.; Del Corso, A.; Mura, U.
New role for leucyl aminopeptidase in glutathione turnover
Biochem. J.
378
35-44
2004
Bos taurus (P00727), Bos taurus
Jsch, C.; Klotz, L.O.; Sies, H.
Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver
Biol. Chem.
384
213-218
2003
Rattus norvegicus
Erhardt, S.; Weston, J.
Development of a working model of the active site in bovine lens leucine aminopeptidase: a density functional investigation
ChemBioChem
3
101-104
2002
Bos taurus
Bozic, N.; Vuicic, Z.; Nenadovic, V.; Ivanovic, J.
Partial purification and characterization of midgut leucyl aminopeptidase of Morimus funereus (coleoptera: cerambycidae) larvae
Comp. Biochem. Physiol. B
134
231-241
2003
Morimus funereus
Donald, K.M.; Day, A.J.; Smerdon, G.R.; Cross, L.J.; Hawkins, A.J.S.
Quantification of gene transcription and enzyme activity for functionally important proteolytic enzymes during early development in the Pacific oyster Crassostrea gigas
Comp. Biochem. Physiol. B
136
383-392
2003
Crassostrea gigas
Khan, A.R.; Nirasawa, S.; Kaneko, S.; Shimonishi, T.; Hyashi, K.
Characterization of a solvent resistant and thermostable aminopeptidase from the hyperthermophilic bacterium, Aquifex aeolicus
Enzyme Microb. Technol.
27
83-88
2000
Aquifex aeolicus
Gu, Y.Q.; Walling, L.L.
Specificity of the wound-induced leucine aminopeptidase (LAP-A) of tomato. Activity on dipeptide and tripeptide substrates
Eur. J. Biochem.
267
1178-1187
2000
Escherichia coli, Solanum lycopersicum, Sus scrofa
Gu, Y.Q.; Walling, L.L.
Identification of residues critical for activity of the wound-induced leucine aminopeptidase (LAP-A) of tomato
Eur. J. Biochem.
269
1630-1640
2002
Solanum lycopersicum
Hattori, A.; Kitatani, K.; Matsumoto, H.; Miyazawa, S.; Rogi, T.; Tsuruoka, N.; Mizutani, S.; Natori, Y.; Tsujimoto, M.
Characterization of recombinant human adipocyte-derived leucine aminopeptidase expressed in chinese hamster ovary cells
J. Biochem.
128
755-762
2000
Homo sapiens
Morty, R.E.; Morehead, J.
Cloning and characterization of a leucyl aminopeptidase from three pathogenic Leishmania species
J. Biol. Chem.
29
26057-26065
2002
Leishmania major (Q7KF27), Leishmania donovani (Q95V75), Leishmania amazonensis (Q95V76)
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Karadzic, I.; Izrael, L.; Gojgic-Cvijovic, G.; Vujcic, Z.
Leucine aminopeptidase from Streptomyces hygroscopicus is controlled by a low molecular weight inhibitor
J. Biosci. Bioeng.
94
309-314
2002
Streptomyces hygroscopicus
Grembecka, J.; Mucha, A.; Cierpicki, T.; Kafarski, P.
The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity
J. Med. Chem.
46
2641-2655
2003
Sus scrofa
Van den Tweel, W.J.J.; van Dooren, T.J.G.M.; de Jonge, P.H.; Kaptein, B.; Duchateau, A.L.L.; Kamphuis, J.
Ochrobacterium anthropi NCIMB 40321: a new biocatalyst with broad-spectrum L-specific amidase activity
Appl. Microbiol. Biotechnol.
39
296-300
1993
Pseudomonas putida
-
Cappiello, M.; Alterio, V.; Amodeo, P.; Del Corso, A.; Scaloni, A.; Pedone, C.; Moschini, R.; De Donatis, G.M.; De Simone, G.; Mura, U.
Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase
Biochemistry
45
3226-3234
2006
Bos taurus (P00727), Bos taurus
Mitsui, T.; Nomura, S.; Itakura, A.; Mizutani, S.
Role of aminopeptidases in the blood pressure regulation
Biol. Pharm. Bull.
27
768-771
2004
Homo sapiens
Hattori, A.; Tsujimoto, M.
Processing of antigenic peptides by aminopeptidases
Biol. Pharm. Bull.
27
777-780
2004
Homo sapiens
Arima, K.; Uchikoba, T.; Shimada, M.; Yonezawa, H.; Kaneda, M.
Purification and some properties of an aminopeptidase from the seeds of Cannabis sativa
Biosci. Biotechnol. Biochem.
64
1055-1057
2000
Cannabis sativa
Yamazaki, T.; Akada, T.; Niizeki, O.; Suzuki, T.; Miyashita, H.; Sato, Y.
Puromycin-insensitive leucyl-specific aminopeptidase (PILSAP) binds and catalyzes PDK1, allowing VEGF-stimulated activation of S6K for endothelial cell proliferation and angiogenesis
Blood
104
2345-2352
2004
Mus musculus
Dopido, R.; Rodriguez, C.; Gomez, T.; Acosta, N.G.; Diaz, M.
Isolation and characterization of enterocytes along the intestinal tract of the gilthead seabream (Sparus aurata L.)
Comp. Biochem. Physiol. A
139
21-31
2004
Sparus aurata
Goto, Y.; Hattori, A.; Ishii, Y.; Tsujimoto, M.
Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1
FEBS Lett.
580
1833-1838
2006
Homo sapiens
Harata, T.; Ando, H.; Iwase, A.; Nagasaka, T.; Mizutani, S.; Kikkawa, F.
Localization of angiotensin II, the AT1 receptor, angiotensin-converting enzyme, aminopeptidase A, adipocyte-derived leucine aminopeptidase, and vascular endothelial growth factor in the human ovary throughout the menstrual cycle
Fertil. Steril.
86
433-439
2006
Homo sapiens
Pokharel, D.R.; Rai, R.; Kumar, P.; Chaturvedi, C.M.; Rathaur, S.
Tissue localization of collagenase and leucine aminopeptidase in the bovine filarial parasite Setaria cervi
Filaria J.
5
DOI:10.1186/1475-2883-5-7
2006
Setaria cervi
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Straeter, N.; Lipscomb, W.N.
Leucine aminopeptidase
Handbook of Metalloproteins (Messerschmidt, A. ; Huber R. Wieghardt, K. ; Poulos, T. , eds. ) Wiley
3
199-207
2004
Sus scrofa
-
Straeter, N.; Lipscomb, W.N.
Leucyl aminopeptidase (animal)
Handbook of Proteolytic Enzymes (2nd Edition)
1
896-901
2004
Bos taurus, Homo sapiens, Sus scrofa
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Walling, L.L.
Leucyl aminopeptidase (plant)
Handbook of Proteolytic Enzymes (2nd Edition)
1
901-905
2004
Arabidopsis thaliana, Brassica sp., Hordeum vulgare, Solanum lycopersicum, Phaseolus vulgaris, Solanum tuberosum, Spinacia oleracea
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McCarthy, E.; Stack, C.; Donnelly, S.M.; Doyle, S.; Mann, V.H.; Brindley, P.J.; Stewart, M.; Day, T.A.; Maule, A.G.; Dalton, J.P.
Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum
Int. J. Parasitol.
34
703-714
2004
Schistosoma mansoni, Schistosoma japonicum (Q9GQ37), Schistosoma japonicum
Shibata, T.; Motomura, J.; Yamaguchi, K.; Kiriyama, T.; Fujii, A.; Hama, Y.; Nakamura, T.
Distribution of digestive enzymes in the rabbitfish Siganus fuscescens
ITE Lett. Batteries New Technol. Med.
6
368-371
2005
Siganus fuscescens
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Erhardt, S.; Jaime, E.; Weston, J.
A water sluice is generated in the active site of bovine lens leucine aminopeptidase
J. Am. Chem. Soc.
127
3654-3655
2005
Bos taurus (P00727), Bos taurus
Fricke, B.; Aurich, H.
Periplasmic aminopeptidases in Acinetobacter calcoaceticus and Pseudomonas aeruginosa
J. Basic Microbiol.
33
291-299
1993
Acinetobacter calcoaceticus, Pseudomonas aeruginosa, Acinetobacter calcoaceticus 69-V
Jensch, T.; Fricke, B.
Localization of alanyl aminopeptidase and leucyl aminopeptidase in cells of Pseudomonas aeruginosa by application of different methods for periplasm release
J. Basic Microbiol.
37
115-128
1997
Pseudomonas aeruginosa
Cahan, R.; Axelrad, I.; Safrin, M.; Ohmann, D.E.; Kessler, E.
A secreted aminopeptidase of Pseudomonas aeruginosa
J. Biol. Chem.
276
43645-43652
2001
Pseudomonas aeruginosa
Russo, S.; Baumann, U.
Crystal structure of a dodecameric tetrahedral-shaped aminopeptidase
J. Biol. Chem.
279
51275-51281
2004
Pyrococcus horikoshii (O59196), Pyrococcus horikoshii OT-3 (O59196)
Gardiner, D.L.; Trenholme, K.R.; Skinner-Adams, T.S.; Stack, C.M.; Dalton, J.P.
Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites. Target for the antimalarial activity of bestatin
J. Biol. Chem.
281
1741-1745
2006
Plasmodium falciparum
Abouel-Nour, M.F.; Lotfy, M.; El-Kady, I.; El-Shahat, M.; Doughty, B.L.
Localization of leucine aminopeptidase in the Schistosoma mansoni eggs and in liver tissue from infected mice
J. Egypt. Soc. Parasitol.
35
147-156
2005
Schistosoma mansoni
Fruci, D.; Ferracuti, S.; Limongi, M.Z.; Cunsolo, V.; Giorda, E.; Fraioli, R.; Sibilio, L.; Carroll, O.; Hattori, A.; Van Endert, P.M.; Giacomini, P.
Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines
J. Immunol.
176
4869-4879
2006
Homo sapiens, Homo sapiens (Q6P179)
Millership, J.J.; Chappell, C.; Okhuysen, P.C.; Snowden, K.F.
Characterization of aminopeptidase activity from three species of microsporidia: Encephalitozoon cuniculi, Encephalitozoon hellem, and Vittaforma corneae
J. Parasitol.
88
843-848
2002
Encephalitozoon cuniculi, Encephalitozoon hellem
Syros, T.; Yupsanis, T.; Petkou, D.; Economou, A.S.
Protein, leucine aminopeptidase, esterase, acid phosphatase and photosynthetic responses of oleander (Nerium oleander L.) during cold acclimation and freezing treatments
J. Plant Physiol.
162
886-894
2005
Nerium oleander
Nampoothiri, K.M.; Nagy, V.; Kovacs, K.; Szakacs, G.; Pandey, A.
L-Leucine aminopeptidase production by filamentous Aspergillus fungi
Lett. Appl. Microbiol.
41
498-504
2005
Aspergillus oryzae, Aspergillus sojae, Aspergillus oryzae NRRL 6270
Ochanda, J.O.; Oduor, E.A.C.; Galun, R.; Imbuga, M.O.; Mumcuoglu, K.Y.
Partial purification of the aminopeptidase from the midgut of the human body louse, Pediculus humanus humanus
Physiol. Entomol.
25
242-246
2000
Pediculus humanus corporis
Ogiwara, N.; Amano, T.; Satoh, M.; Shioi, Y.
Leucine aminopeptidase from etiolated barley seedlings: characterization and partial purification of isoforms
Plant Sci.
168
575-581
2005
Hordeum vulgare
Pokharel, D.R.; Rathaur, S.
Purification and characterization of a leucine aminopeptidase from the bovine filarial parasite Setaria cervi
Acta Trop.
106
1-8
2008
Setaria cervi
Witek, B.; Ochwanowska, E.; Baranowska, D.; Kolataj, A.
The effect of selection for body weight on the activity of lysosomal enzymes in the liver and kidney of mice
Anim. Sci. Pap. Rep.
25
119-125
2007
Mus musculus
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Tibaldi, E.; Hakim, Y.; Uni, Z.; Tulli, F.; de Francesco, M.; Luzzana, U.; Harpaz, S.
Effects of the partial substitution of dietary fish meal by differently processed soybean meals on growth performance, nutrient digestibility and activity of intestinal brush border enzymes in the European sea bass (Dicentrarchus labrax)
Aquaculture
261
182-193
2006
Dicentrarchus labrax
Kvale, A.; Mangor-Jensen, A.; Moren, M.; Espe, M.; Hamre, K.
Development and characterisation of some intestinal enzymes in Atlantic cod (Gadus morhua L.) and Atlantic halibut (Hippoglossus hippoglossus L.) larvae
Aquaculture
264
457-468
2007
Gadus morhua, Hippoglossus hippoglossus
Albrecht, S.; Defoin, A.; Salomon, E.; Tarnus, C.; Wetterholm, A.; Haeggstroem, J.Z.
Synthesis and structure activity relationships of novel non-peptidic metallo-aminopeptidase inhibitors
Bioorg. Med. Chem.
14
7241-7257
2006
Bos taurus
Rueda, E.; Leon, M.; Castaneda, M.; Mendez, A.; Michelangeli, C.
Effects of concanavalin A on intestinal brush border enzyme activity in broiler chickens
Br. Poult. Sci.
48
696-702
2007
Gallus gallus
Korenova, M.; Stano, J.; Micieta, K.; Blanarikova, V.
Identification and determination of aminopeptidase activities secreted by lemon balm
Chem. Nat. Compd.
43
201-204
2007
Melissa officinalis
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Bozic, N.; Ivanovic, J.; Nenadovic, V.; Bergstroem, J.; Larsson, T.; Vujcic, Z.
Purification and properties of major midgut leucyl aminopeptidase of Morimus funereus (Coleoptera, Cerambycidae) larvae
Comp. Biochem. Physiol. B
149
454-462
2008
Morimus funereus
Herrera-Camacho, I.; Rosas-Murrieta, N.H.; Rojo-Dominguez, A.; Millan, L.; Reyes-Leyva, J.; Santos-Lopez, G.; Suarez-Rendueles, P.
Biochemical characterization and structural prediction of a novel cytosolic leucyl aminopeptidase of the M17 family from Schizosaccharomyces pombe
FEBS J.
274
6228-6240
2007
Schizosaccharomyces pombe (Q09735), Schizosaccharomyces pombe
Kraft, M.; Schleberger, C.; Weckesser, J.; Schulz, G.E.
Binding structure of the leucine aminopeptidase inhibitor microginin FR1
FEBS Lett.
580
6943-6947
2006
Bos taurus (P00727), Bos taurus
Parra, A.M.; Rosas, A.; Lazo, J.P.; Viana, M.T.
Partial characterization of the digestive enzymes of Pacific bluefin tuna Thunnus orientalis under culture conditions
Fish Physiol. Biochem.
33
223-231
2007
Thunnus orientalis
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Abe, M.; Sato, Y.
Puromycin insensitive leucyl-specific aminopeptidase (PILSAP) is required for the development of vascular as well as hematopoietic system in embryoid bodies
Genes Cells
11
719-729
2006
Mus musculus
Fernandes, V.L.; Bhasin, D.K.; Rana, S.V.
Study of enzyme activities in the descending part of the duodenum in patients of duodenal ulcer
Indian J. Clin. Biochem.
21(1)
169-172
2006
Homo sapiens
Hatta, T.; Kazama, K.; Miyoshi, T.; Umemiya, R.; Liao, M.; Inoue, N.; Xuan, X.; Tsuji, N.; Fujisaki, K.
Identification and characterisation of a leucine aminopeptidase from the hard tick Haemaphysalis longicornis
Int. J. Parasitol.
36
1123-1132
2006
Haemaphysalis longicornis (Q0KKA6), Haemaphysalis longicornis
Stack, C.M.; Lowther, J.; Cunningham, E.; Donnelly, S.; Gardiner, D.L.; Trenholme, K.R.; Skinner-Adams, T.S.; Teuscher, F.; Grembecka, J.; Mucha, A.; Kafarski, P.; Lua, L.; Bell, A.; Dalton, J.P.
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development
J. Biol. Chem.
282
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2007
Plasmodium falciparum (Q8IL11), Plasmodium falciparum, Plasmodium falciparum M17 (Q8IL11), Plasmodium falciparum M17
Suzuki, T.; Abe, M.; Miyashita, H.; Kobayashi, T.; Sato, Y.
Puromycin insensitive leucyl-specific aminopeptidase (PILSAP) affects RhoA activation in endothelial cells
J. Cell. Physiol.
211
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2007
Mus musculus
Hsu, C.; Huang, Y.; Yin, M.; Lin, S.
Effect of yam (Dioscorea alata compared to Dioscorea japonica) on gastrointestinal function and antioxidant activity in mice
J. Food Sci.
71
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Mus musculus
Shin, E.; Seifert, U.; Urban, S.; Truong, K.; Feinstone, S.M.; Rice, C.M.; Kloetzel, P.; Rehermann, B.
Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type I interferon in the hepatitis C virus-infected liver
J. Interferon Cytokine Res.
27
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2008
Homo sapiens, Pan troglodytes
Skinner-Adams, T.S.; Lowther, J.; Teuscher, F.; Stack, C.M.; Grembecka, J.; Mucha, A.; Kafarski, P.; Trenholme, K.R.; Dalton, J.P.; Gardiner, D.L.
Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds
J. Med. Chem.
50
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2007
Plasmodium falciparum, Plasmodium falciparum M17
Mishra, S.; Dubey, R.S.
Inhibition of ribonuclease and protease activities in arsenic exposed rice seedlings: role of proline as enzyme protectant
J. Plant Physiol.
163
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2006
Oryza sativa, Rattus norvegicus, Rattus norvegicus Wistar
Siringan, P.; Raksakulthai, N.; Yongsawatdigul, J.
Source and changes of proteinase activities of Indian anchovy (Stolephorus spp.) during fish sauce fermentation
J. Sci. Food Agric.
86
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2006
Stolephorus indicus
Zhao, G.M.; Wang, Y.L.; Tian, W.; Zhou, G.H.; Xu, X.L.; Liu, Y.X.
Changes in arginyl and leucyl aminopeptidase activities in biceps femoris along Jinhua ham processing
Meat Sci.
74
450-458
2006
Sus scrofa
Jung, K.; Ahn, K.; Chae, C.
Decreased activity of brush border membrane-bound digestive enzymes in small intestines from pigs experimentally infected with porcine epidemic diarrhea virus
Res. Vet. Sci.
81
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2006
Sus scrofa
Tholander, F.; Haeggstroem, J.Z.
Assay for rapid analysis of the tri-peptidase activity of LTA4 hydrolase
Proteins
67
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2007
Homo sapiens
Kawai, M.; Araragi, K.; Shimizu, Y.; Hara, Y.
Identification of placental leucine aminopeptidase and triton-slowed aminopeptidase N in serum of pregnant women
Clin. Chim. Acta
400
37-41
2009
Homo sapiens
Chi, M.C.; Ong, P.L.; Hsu, W.H.; Chen, Y.H.; Huang, H.B.; Lin, L.L.
Role of the invariant Asn345 and Asn435 residues in a leucine aminopeptidase from Bacillus kaustophilus as evaluated by site-directed mutagenesis
Int. J. Biol. Macromol.
43
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2008
Geobacillus kaustophilus (Q7X2C8), Geobacillus kaustophilus
Wu, G.P.; Cao, M.J.; Chen, Y.; Liu, B.X.; Su, W.J.
Leucine aminopeptidase from red sea bream (Pagrus major) skeletal muscle: purification, characterization, cellular location, and tissue distribution
J. Agric. Food Chem.
56
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2008
Pagrus major
Song, S.M.; Park, J.H.; Kim, J.; Kim, S.I.; Hong, Y.C.; Kong, H.H.; Chung, D.I.
Identification and characterization of Paragonimus westermani leucine aminopeptidase
Parasitol. Int.
57
334-341
2008
Paragonimus westermani (A1Z0K2), Paragonimus westermani
Alasbahi, R.; Melzig, M.F.
Screening of some Yemeni medicinal plants for inhibitory activity against peptidases
Pharmazie
63
86-88
2008
Homo sapiens
Lutfullah, G.; Azhar, N.; Amin, F.; Khan, Z.; Azim, M.K.; Shouqat, K.; Noor, S.; Ali, R.
Structural bioinformatics of Vibrio cholerae aminopeptidase A (PepA) monomer
Protein Pept. Lett.
16
36-45
2009
Vibrio cholerae (P0C6E1)
Huang, H.; Tanaka, H.; Hammock, B.D.; Morisseau, C.
Novel and highly sensitive fluorescent assay for leucine aminopeptidases
Anal. Biochem.
391
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Sus scrofa
Maric, S.; Donnelly, S.M.; Robinson, M.W.; Skinner-Adams, T.; Trenholme, K.R.; Gardiner, D.L.; Dalton, J.P.; Stack, C.M.; Lowther, J.
The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: importance of active site metal ions in the binding of substrates and inhibitors
Biochemistry
48
5435-5439
2009
Plasmodium falciparum
Vujcic, Z.; Loncar, N.; Dojnov, B.; Milovanovic, A.; Vujcic, M.; Bozic, N.
Characterisation of leucyl aminopeptidase from Solanum tuberosum tuber
Food Chem.
121
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Solanum tuberosum
Laslo, A.C.; Ganea, E.; Obinger, C.
Refolding of hexameric porcine leucine aminopeptidase using a cationic detergent and dextrin-10 as artificial chaperones
J. Biotechnol.
140
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2009
Sus scrofa
Hatta, T.; Tsuji, N.; Miyoshi, T.; Alim, M.A.; Islam, M.K.; Fujisaki, K.
Leucine aminopeptidase in the ixodid tick Haemaphysalis longicornis: endogenous expression profiles in midgut
J. Vet. Med. Sci.
71
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2009
Haemaphysalis longicornis, Haemaphysalis longicornis Okayama
Rinaldi, G.; Morales, M.E.; Alrefaei, Y.N.; Cancela, M.; Castillo, E.; Dalton, J.P.; Tort, J.F.; Brindley, P.J.
RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs
Mol. Biochem. Parasitol.
167
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2009
Schistosoma mansoni (P91803), Schistosoma mansoni
Jia, H.; Nishikawa, Y.; Luo, Y.; Yamagishi, J.; Sugimoto, C.; Xuan, X.
Characterization of a leucine aminopeptidase from Toxoplasma gondii
Mol. Biochem. Parasitol.
170
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2010
Toxoplasma gondii, Toxoplasma gondii RH
Lee, J.Y.; Song, S.M.; Seok, J.W.; Jha, B.K.; Han, E.T.; Song, H.O.; Yu, H.S.; Hong, Y.; Kong, H.H.; Chung, D.I.
M17 leucine aminopeptidase of the human malaria parasite Plasmodium vivax
Mol. Biochem. Parasitol.
170
45-48
2010
Plasmodium vivax (A5K3U9), Plasmodium vivax
Hatta, T.; Tsuji, N.; Miyoshi, T.; Islam, M.K.; Alim, M.A.; Yamaji, K.; Anisuzzaman, K.; Fujisaki, K.
Leucine aminopeptidase, HlLAP, from the ixodid tick Haemaphysalis longicornis, plays vital roles in the development of oocytes
Parasitol. Int.
59
286-289
2010
Haemaphysalis longicornis
Jia, H.; Terkawi, M.A.; Aboge, G.O.; Goo, Y.K.; Luo, Y.; Li, Y.; Yamagishi, J.; Nishikawa, Y.; Igarashi, I.; Sugimoto, C.; Fujisaki, K.; Xuan, X.
Characterization of a leucine aminopeptidase of Babesia gibsoni
Parasitology
136
945-952
2009
Babesia gibsoni (C5NSV0), Babesia gibsoni
Fowler, J.H.; Narvaez-Vasquez, J.; Aromdee, D.N.; Pautot, V.; Holzer, F.M.; Walling, L.L.
Leucine aminopeptidase regulates defense and wound signaling in tomato downstream of jasmonic acid
Plant Cell
21
1239-1251
2009
Solanum lycopersicum (Q10712), Solanum lycopersicum
Lin, S.; Chen, L.; Wen, C.; Chu, W.
Extracellular leucine aminopeptidase produced by Aspergillus oryzae LL1 and LL2
Afr. J. Microbiol. Res.
4
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2010
Aspergillus oryzae, Aspergillus oryzae LL1
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Yoon, H.Y.; Shim, S.H.; Baek, L.J.; Hong, J.I.
Small-molecule probe using dual signals to monitor leucine aminopeptidase activity
Bioorg. Med. Chem. Lett.
21
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2011
Sus scrofa
Cadavid-Restrepo, G.; Gastardelo, T.; Faudry, E.; De Almeida, H.; Bastos, I.; Negreiros, R.; Lima, M.; Assump??o, T.; Almeida, K.; Ragno, M.; Ebel, C.; Ribeiro, B.; Felix, C.; Santana, J.
The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases
BMC Biochem.
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46
2011
Trypanosoma cruzi (Q4DZJ3), Trypanosoma cruzi
Matsushita-Morita, M.; Tada, S.; Suzuki, S.; Hattori, R.; Marui, J.; Furukawa, I.; Yamagata, Y.; Amano, H.; Ishida, H.; Takeuchi, M.; Kashiwagi, Y.; Kusumoto, K.
Overexpression and characterization of an extracellular leucine aminopeptidase from Aspergillus oryzae
Curr. Microbiol.
62
557-564
2011
Aspergillus oryzae, Aspergillus oryzae RIB 40
Premarathne, A.A.; Leung, D.W.
Characterization of activity of a potential food-grade leucine aminopeptidase from kiwifruit
Enzyme Res.
2010
517283
2010
Actinidia deliciosa
Ye, X.; Ng, T.
Purification and characterisation of a leucine aminopeptidase from Lactococcus lactis subsp. lactis cultured in skim milk
Int. Dairy J.
21
501-503
2011
Lactococcus lactis subsp. lactis
Georgiadou, D.; Hearn, A.; Evnouchidou, I.; Chroni, A.; Leondiadis, L.; York, I.A.; Rock, K.L.; Stratikos, E.
Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1
J. Immunol.
185
1584-1592
2010
Homo sapiens
Waditee-Sirisattha, R.; Shibato, J.; Rakwal, R.; Sirisattha, S.; Hattori, A.; Nakano, T.; Takabe, T.; Tsujimoto, M.
The Arabidopsis aminopeptidase LAP2 regulates plant growth, leaf longevity and stress response
New Phytol.
191
958-969
2011
Arabidopsis thaliana
Kang, J.; Ju, H.; Sohn, W.; Na, B.
Molecular cloning and characterization of a M17 leucine aminopeptidase of Cryptosporidium parvum
Parasitology
138
682-690
2011
Cryptosporidium parvum (Q5CRI9), Cryptosporidium parvum, Cryptosporidium parvum Iowa II (Q5CRI9)
Boulila-Zoghlami, L.; Gallusci, P.; Holzer, F.M.; Basset, G.J.; Djebali, W.; Chaibi, W.; Walling, L.L.; Brouquisse, R.
Up-regulation of leucine aminopeptidase-A in cadmium-treated tomato roots
Planta
234
857-863
2011
Solanum lycopersicum (Q10712), Solanum lycopersicum (Q8GZD8), Solanum lycopersicum
Chen, S.; Cao, M.; Su, W.; Wu, G.
Purification and characterization of a novel leucine aminopeptidase from the earthworm Eisenia foetida
Process Biochem.
46
1641-1648
2011
Eisenia fetida
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Maggioli, G.; Acosta, D.; Silveira, F.; Rossi, S.; Giacaman, S.; Basika, T.; Gayo, V.; Rosadilla, D.; Roche, L.; Tort, J.; Carmona, C.
The recombinant gut-associated M17 leucine aminopeptidase in combination with different adjuvants confers a high level of protection against Fasciola hepatica infection in sheep
Vaccine
29
9057-9063
2011
Fasciola hepatica
Dura, M.A.; Receveur-Brechot, V.; Andrieu, J.P.; Ebel, C.; Schoehn, G.; Roussel, A.; Franzetti, B.
Characterization of a TET-like aminopeptidase complex from the hyperthermophilic archaeon Pyrococcus horikoshii
Biochemistry
44
3477-3486
2005
Pyrococcus horikoshii (O59196), Pyrococcus horikoshii, Pyrococcus horikoshii OT-3 (O59196)
Borissenko, L.; Groll, M.
Crystal structure of TET protease reveals complementary protein degradation pathways in prokaryotes
J. Mol. Biol.
346
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2005
Pyrococcus horikoshii (O59196), Pyrococcus horikoshii OT-3 (O59196)
Slutskaya, E.S.; Bezsudnova, E.Y.; Mardanov, A.V.; Gumerov, V.M.; Rakitina, T.V.; Popov, V.O.; Lipkin, V.M.
Characterization of a novel M42 aminopeptidase from crenarchaeon Desulfurococcus kamchatkensis
Dokl. Biochem. Biophys.
442
30-32
2012
Desulfurococcus amylolyticus (B8D484), Desulfurococcus amylolyticus, Desulfurococcus amylolyticus DSM 18924 (B8D484)
Duprez, K.; Scranton, M.A.; Walling, L.L.; Fan, L.
Structure of tomato wound-induced leucine aminopeptidase sheds light on substrate specificity
Acta Crystallogr. Sect. D
70
1649-1658
2014
Solanum lycopersicum (Q10712), Solanum lycopersicum
Modak, J.K.; Roujeinikova, A.
Cloning, purification and preliminary crystallographic analysis of the Helicobacter pylori leucyl aminopeptidase-bestatin complex
Acta Crystallogr. Sect. F
69
1011-1014
2013
Helicobacter pylori
Carroll, R.K.; Veillard, F.; Gagne, D.T.; Lindenmuth, J.M.; Poreba, M.; Drag, M.; Potempa, J.; Shaw, L.N.
The Staphylococcus aureus leucine aminopeptidase is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine
Biol. Chem.
394
791-803
2013
Staphylococcus aureus
Liew, S.M.; Tay, S.T.; Puthucheary, S.D.
Enzymatic and molecular characterisation of leucine aminopeptidase of Burkholderia pseudomallei
BMC Microbiol.
13
110
2013
Burkholderia pseudomallei, Burkholderia pseudomallei NCTC 13178
Changklungmoa, N.; Chaithirayanon, K.; Kueakhai, P.; Meemon, K.; Riengrojpitak, S.; Sobhon, P.
Molecular cloning and characterization of leucine aminopeptidase from Fasciola gigantica
Exp. Parasitol.
131
283-291
2012
Fasciola gigantica
Scranton, M.A.; Yee, A.; Park, S.Y.; Walling, L.L.
Plant leucine aminopeptidases moonlight as molecular chaperones to alleviate stress-induced damage
J. Biol. Chem.
287
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2012
Solanum lycopersicum (Q10712), Solanum lycopersicum (Q8GZD8), Solanum lycopersicum
Papakyriakou, A.; Zervoudi, E.; Tsoukalidou, S.; Mauvais, F.X.; Sfyroera, G.; Mastellos, D.C.; van Endert, P.; Theodorakis, E.A.; Vourloumis, D.; Stratikos, E.
3,4-diaminobenzoic acid derivatives as inhibitors of the oxytocinase subfamily of m1 aminopeptidases with immune-regulating properties
J. Med. Chem.
58
1524-1543
2015
Homo sapiens (Q6P179), Homo sapiens (Q9NZ08), Homo sapiens
Kim, J.K.; Natarajan, S.; Park, H.; Huynh, K.H.; Lee, S.H.; Kim, J.G.; Ahn, Y.J.; Kang, L.W.
Crystal structure of XoLAP, a leucine aminopeptidase, from Xanthomonas oryzae pv. oryzae
J. Microbiol.
51
627-632
2013
Xanthomonas oryzae (Q5H4N2), Xanthomonas oryzae
Hernandez-Moreno, A.; Perdomo-Abundez, F.; Perez-Medina Martinez, V.; Luna-Barcenas, G.; Villasenor-Ortega, F.; Perez, N.; Lopez-Morales, C.; Flores-Ortiz, L.; Medina-Rivero, E.
Structural and functional characterization of a recombinant leucine aminopeptidase
J. Mol. Catal. B
113
39-46
2015
Vibrio proteolyticus
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Carroll, R.K.; Robison, T.M.; Rivera, F.E.; Davenport, J.E.; Jonsson, I.M.; Florczyk, D.; Tarkowski, A.; Potempa, J.; Koziel, J.; Shaw, L.N.
Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus
Microbes Infect.
14
989-999
2012
Staphylococcus aureus
Kang, J.; Ju, H.; Ju, J.; Sohn, W.; Kim, T.; Bahk, Y.; Hong, S.; Na, B.
Comparative biochemical and functional properties of two leucine aminopeptidases of Clonorchis sinensis
Mol. Biochem. Parasitol.
182
17-26
2012
Clonorchis sinensis (C6FWG9), Clonorchis sinensis (C6FWH0), Clonorchis sinensis
Deng, C.; Sun, J.; Li, X.; Wang, L.; Hu, X.; Wang, X.; Chen, W.; Lv, X.; Liang, C.; Li, W.; Huang, Y.; Li, R.; Wu, Z.; Yu, X.; Xu, J.
Molecular identification and characterization of leucine aminopeptidase 2, an excretory-secretory product of Clonorchis sinensis
Mol. Biol. Rep.
39
9817-9826
2012
Clonorchis sinensis (C6FWG9), Clonorchis sinensis
Jarocki, V.M.; Santos, J.; Tacchi, J.L.; Raymond, B.B.; Deutscher, A.T.; Jenkins, C.; Padula, M.P.; Djordjevic, S.P.
MHJ_0461 is a multifunctional leucine aminopeptidase on the surface of Mycoplasma hyopneumoniae
Open biology
5
140175
2015
Mycoplasma hyopneumoniae (Q4A9M4), Mycoplasma hyopneumoniae
Changklungmoa, N.; Kueakhai, P.; Riengrojpitak, S.; Chaithirayanon, K.; Chaichanasak, P.; Preyavichyapugdee, N.; Chantree, P.; Sansri, V.; Itagaki, T.; Sobhon, P.
Immunization with recombinant leucine aminopeptidase showed protection against Fasciola gigantica in mice
Parasitol. Res.
112
3653-3659
2013
Fasciola gigantica
Ratnayake, S.; Selvarkumar, P.; Hayashi, K.
A putative proline iminopeptidase of Thermotoga maritima is a leucine aminopeptidase with lysine-p-nitroanilide hydrolyzing activity
Enzyme Microb. Technol.
32
414-421
2003
Thermotoga maritima (Q9WXP9), Thermotoga maritima DSM 3109 (Q9WXP9)
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Huang, W.Q.; Zhong, L.F.; Meng, Z.Z.; You, Z.J.; Li, J.Z.; Luo, X.C.
The structure and enzyme characteristics of a recombinant leucine aminopeptidase rLap1 from Aspergillus sojae and its application in debittering
Appl. Biochem. Biotechnol.
177
190-206
2015
Aspergillus sojae (Q8J2N2), Aspergillus sojae, Aspergillus sojae GIM3.30 (Q8J2N2)
Park, H.; Shim, J.S.; Kim, B.S.; Jung, H.J.; Huh, T.L.; Kwon, H.J.
Purpurin inhibits adipocyte-derived leucine aminopeptidase and angiogenesis in a zebrafish model
Biochem. Biophys. Res. Commun.
450
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2014
Danio rerio, Homo sapiens
Rout, S.; Mahapatra, R.K.
In silico screening of novel inhibitors of M17 leucine amino peptidase (LAP) of Plasmodium vivax as therapeutic candidate
Biomed. Pharmacother.
82
192-201
2016
Plasmodium vivax (A5K3U9), Plasmodium vivax, Plasmodium vivax Salvador I (A5K3U9)
Zhang, H.; Wang, H.; Liu, R.; Wang, L.; Song, L.
Cloning and characterization of a leucine aminopeptidase from Pseudoalteromonas telluritireducens DSM 16098, a strain isolated from hydrothermal vents fluid
Deep-Sea Res. Part I: Oceanogr. Res. Pap.
138
114-121
2018
Pseudoalteromonas telluritireducens (A0A3S6IVW5), Pseudoalteromonas telluritireducens DSM 16098 (A0A3S6IVW5)
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Wu, H.; Jiang, W.; Li, B.; Yang, H.; Zhao, X.; Zhang, H.; Wang, S.; Peng, L.; Wang, L.; Wang, X.; Dai, G.; Fang, C.
A new method to evaluate the enzyme-suppressing activity of a leucine aminopeptidase 3 inhibitor
Drug Discov. Ther.
13
17-21
2019
Homo sapiens (P28838), Homo sapiens
Zhao, T.; Zhang, Y.; Wu, H.; Wang, D.; Chen, Y.; Zhu, M.-J.; Ma, L.Z.
Extracellular aminopeptidase modulates biofilm development of Pseudomonas aeruginosa by affecting matrix exopolysaccharide and bacterial cell death
Environ. Microbiol. Rep.
10
583-593
2018
Pseudomonas aeruginosa (Q9HZQ8), Pseudomonas aeruginosa, Pseudomonas aeruginosa ATCC 15692 (Q9HZQ8), Pseudomonas aeruginosa 1C (Q9HZQ8), Pseudomonas aeruginosa PRS 101 (Q9HZQ8), Pseudomonas aeruginosa DSM 22644 (Q9HZQ8), Pseudomonas aeruginosa CIP 104116 (Q9HZQ8), Pseudomonas aeruginosa LMG 12228 (Q9HZQ8), Pseudomonas aeruginosa JCM 14847 (Q9HZQ8)
Zhang, S.; Cai, X.; Luo, X.; Wang, S.; Guo, A.; Hou, J.; Wu, R.
Molecular cloning and characterization of leucine aminopeptidase gene from Taenia pisiformis
Exp. Parasitol.
186
1-9
2018
Taenia pisiformis (A0A2I7M6F6), Taenia pisiformis
Nguyen Le Minh, P.; Nadal, M.; Charlier, D.
The trigger enzyme PepA (aminopeptidase A) of Escherichia coli, a transcriptional repressor that generates positive supercoiling
FEBS Lett.
590
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2016
Escherichia coli (P68767)
Wu, M.; Yan, M.; Xu, J.; Liang, Y.; Gu, X.; Xie, Y.; Jing, B.; Lai, W.; Peng, X.; Yang, G.
Expression, tissue localization and serodiagnostic potential of Echinococcus granulosus leucine aminopeptidase
Int. J. Mol. Sci.
19
1063-1075
2018
Echinococcus granulosus (A0A336UEJ6), Echinococcus granulosus
Xi, H.; Tian, Y.; Zhou, N.; Zhou, Z.; Shen, W.
Characterization of an N-glycosylated Bacillus subtilis leucine aminopeptidase expressed in Pichia pastoris
J. Basic Microbiol.
55
236-246
2015
Bacillus subtilis (O32106), Bacillus subtilis, Bacillus subtilis Zj016 (O32106)
Fang, C.; Zhang, J.; Yang, H.; Peng, L.; Wang, K.; Wang, Y.; Zhao, X.; Liu, H.; Dou, C.; Shi, L.; Zhao, C.; Liang, S.; Li, D.; Wang, X.
Leucine aminopeptidase 3 promotes migration and invasion of breast cancer cells through upregulation of fascin and matrix metalloproteinases-2/9 expression
J. Cell. Biochem.
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Homo sapiens
Maggioli, G.; Rinaldi, G.; Giaudrone, I.; Berasain, P.; Tort, J.F.; Brindley, P.J.; Carmona, C.
Expression, purification and characterization of two leucine aminopeptidases of the blood fluke, Schistosoma mansoni
Mol. Biochem. Parasitol.
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Schistosoma mansoni
Timm, J.; Valente, M.; Garcixada-Caballero, D.; Wilson, K.; Gonzalez-Pacanowska, D.
Structural characterization of acidic M17 leucine aminopeptidases from the TriTryps and evaluation of their role in nutrient starvation in Trypanosoma brucei
mSphere
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Trypanosoma cruzi marinkellei (H2CS62), Trypanosoma brucei brucei (Q6Q833), Leishmania major (Q7KF27)
Laurinyecz, B.; Vedelek, V.; Kovacs, A.L.; Szilasi, K.; Lipinszki, Z.; Slezak, C.; Darula, Z.; Juhasz, G.; Sinka, R.
Sperm-leucylaminopeptidases are required for male fertility as structural components of mitochondrial paracrystalline material in Drosophila melanogaster sperm
PLoS Genet.
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Drosophila melanogaster (Q500X4), Drosophila melanogaster (Q7K2S9), Drosophila melanogaster (Q7K5K9), Drosophila melanogaster (Q8T4F1), Drosophila melanogaster (Q95R35), Drosophila melanogaster (Q961W5), Drosophila melanogaster (Q9VSM6), Drosophila melanogaster (Q9VSM7), Drosophila melanogaster
Lee, Y.R.; Na, B.K.; Moon, E.K.; Song, S.M.; Joo, S.Y.; Kong, H.H.; Goo, Y.K.; Chung, D.I.; Hong, Y.
Essential role for an M17 leucine aminopeptidase in encystation of Acanthamoeba castellanii
PLoS ONE
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2015
Acanthamoeba castellanii (A0A060A630), Acanthamoeba castellanii
Pena-Diaz, P.; Vancova, M.; Resl, C.; Field, M.C.; Lukes, J.
A leucine aminopeptidase is involved in kinetoplast DNA segregation in Trypanosoma brucei
PLoS Pathog.
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2017
Trypanosoma brucei brucei (Q57W67), Trypanosoma brucei brucei 927/4 GU Tat10.1 (Q57W67)
Valencia, J.W.; de Sa, M.F.; Jimenez, A.V.
Activity of leucine aminopeptidase of Telchin licus licus an important insect pest of sugarcane
Protein Pept. Lett.
21
535-541
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Telchin licus licus
Shevchenko, K.; Dulov, S.; Andreeva, L.; Nagaev, I.; Shevchenko, V.; Radilov, A.; Myasoedov, N.
Stability of His-Phe-Arg-Trp-Pro-Gly-Pro to leucine aminopeptidase, carboxypeptidase Y, and rat nasal mucus, blood, and plasma
Russ. J. Bioorg. Chem.
42
153-161
2016
Rattus norvegicus, Rattus norvegicus Wistar
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