Information on EC 1.4.3.2 - L-amino-acid oxidase

New: Word Map on EC 1.4.3.2
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Search Reference ID:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

EC NUMBER
COMMENTARY hide
1.4.3.2
-
RECOMMENDED NAME
GeneOntology No.
L-amino-acid oxidase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an L-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidative deamination
-
-
-
-
redox reaction
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Alanine, aspartate and glutamate metabolism
-
-
arginine metabolism
-
-
Cysteine and methionine metabolism
-
-
Isoquinoline alkaloid biosynthesis
-
-
L-arginine degradation VIII (arginine oxidase pathway)
-
-
Metabolic pathways
-
-
methionine metabolism
-
-
Phenylalanine metabolism
-
-
Phenylalanine, tyrosine and tryptophan biosynthesis
-
-
Tryptophan metabolism
-
-
Tyrosine metabolism
-
-
Valine, leucine and isoleucine degradation
-
-
SYSTEMATIC NAME
IUBMB Comments
L-amino-acid:oxygen oxidoreductase (deaminating)
A flavoprotein (FAD).
CAS REGISTRY NUMBER
COMMENTARY hide
9000-89-9
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Aplysia californica Cooper 1863
strain Cooper 1863 collected in California
Swissprot
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
Bacillus carotarum
2Pfa
-
-
Manually annotated by BRENDA team
Bacillus carotarum 2Pfa
2Pfa
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
Bothrops sp.
venom
-
-
Manually annotated by BRENDA team
A20
-
-
Manually annotated by BRENDA team
A20
-
-
Manually annotated by BRENDA team
Crotalus terrificus terrificus
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
strain CBS 558.96
-
-
Manually annotated by BRENDA team
strain CBS 558.96
-
-
Manually annotated by BRENDA team
Hebeloma sp.
strains SE5, F-NB01 , F-RS01, R-RS01 and SIV
-
-
Manually annotated by BRENDA team
strain S238N
-
-
Manually annotated by BRENDA team
strain S238N
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
turkey
-
-
Manually annotated by BRENDA team
isozymes MPLAO1, MPLAO2, and MPLAO3
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
no activity in Acinetobacter anitratum
-
-
-
Manually annotated by BRENDA team
no activity in Alcaligenes faecalis
-
-
-
Manually annotated by BRENDA team
no activity in Anabaena variabilis ATCC 29413
-
-
-
Manually annotated by BRENDA team
no activity in Bacillus subtilis
-
-
-
Manually annotated by BRENDA team
no activity in Bacillus subtilis subsp. subtilis
-
-
-
Manually annotated by BRENDA team
no activity in Bacillus subtilis subsp. subtilis NCIB 3610
-
-
-
Manually annotated by BRENDA team
no activity in Diplococcus pneumoniae
-
-
-
Manually annotated by BRENDA team
no activity in Enterobacter aerogenes
-
-
-
Manually annotated by BRENDA team
no activity in Escherichia coli
-
-
-
Manually annotated by BRENDA team
no activity in Klebsiella pneumoniae
-
-
-
Manually annotated by BRENDA team
no activity in Micrococcus tetragenus
-
-
-
Manually annotated by BRENDA team
no activity in Moraxella catarrhalis
-
-
-
Manually annotated by BRENDA team
no activity in Mycobacterium phlei
-
-
-
Manually annotated by BRENDA team
no activity in Prochlorococcus marinus
-
-
-
Manually annotated by BRENDA team
no activity in Prochlorococcus marinus MED4
-
-
-
Manually annotated by BRENDA team
no activity in Prochlorococcus marinus MIT 9211
-
-
-
Manually annotated by BRENDA team
no activity in Prochlorococcus marinus MIT 9312
-
-
-
Manually annotated by BRENDA team
no activity in Prochlorococcus marinus MIT 9313
-
-
-
Manually annotated by BRENDA team
no activity in Prochlorococcus marinus NATL2A
-
-
-
Manually annotated by BRENDA team
no activity in Prochlorococcus marinus SS 120
-
-
-
Manually annotated by BRENDA team
no activity in Pseudomonas aeruginosa
-
-
-
Manually annotated by BRENDA team
no activity in Pseudomonas putida
-
-
-
Manually annotated by BRENDA team
no activity in Pseudomonas putida T1
-
-
-
Manually annotated by BRENDA team
no activity in Serratia marcescens
-
-
-
Manually annotated by BRENDA team
no activity in Shigella flexneri
-
-
-
Manually annotated by BRENDA team
no activity in Staphylococcus aureus
-
-
-
Manually annotated by BRENDA team
no activity in Staphylococcus epidermidis
-
-
-
Manually annotated by BRENDA team
no activity in Streptococcus viridans
-
-
-
Manually annotated by BRENDA team
no activity in Synechococcus sp.
-
-
-
Manually annotated by BRENDA team
no activity in Synechococcus sp. CC9902
-
-
-
Manually annotated by BRENDA team
no activity in Synechococcus sp. JA-2-3B'a(2-13)
-
-
-
Manually annotated by BRENDA team
no activity in Synechococcus sp. JA-3-3Ab
-
-
-
Manually annotated by BRENDA team
no activity in Synechococcus sp. RS9917
-
-
-
Manually annotated by BRENDA team
no activity in Synechococcus sp. WH 8102
-
-
-
Manually annotated by BRENDA team
no activity in Thermosynechococcus elongatus BP-1
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
30 different strains
-
-
Manually annotated by BRENDA team
Providencia sp. PCM 1298
PCM 1298
-
-
Manually annotated by BRENDA team
isolated from the encrusting pore coral Montipora aequituberculata from the Kenting coast of Southern Taiwan
-
-
Manually annotated by BRENDA team
isolated from the encrusting pore coral Montipora aequituberculata from the Kenting coast of Southern Taiwan
-
-
Manually annotated by BRENDA team
strain CPMOR-1; strain CPMOR-2; strain NCIMB 1893T
-
-
Manually annotated by BRENDA team
strain NCIMB 1893T
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Rhodococcus sp. AIU Z-35-1
-
-
-
Manually annotated by BRENDA team
snake
-
-
-
Manually annotated by BRENDA team
Synechococcus cedrorum PCC 6908
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
additional information
-
toxophallin is a highly cytotoxic protein, but differs distinctly from the other death cap toxic protein phallolysin. The interaction of toxophallin with target cells is not mediated by a specific cell surface receptor
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(1,1,2,2-tetrafluoroethyl)-L-cysteine + H2O + O2
2-oxo-3-[(1,1,2,2-tetrafluoroethyl)sulfanyl]propanoic acid + NH3 + H2O2
show the reaction diagram
-
80% of the activity with L-methionine
-
-
?
3,4-dihydroxyphenyl-L-Ala + H2O + O2
3-(3,4-dihydroxyphenyl)-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
alpha-hydroxyisocaproic acid + H2O + O2
2-oxo-4-methylpentanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
alpha-hydroxyvaleric acid + H2O + O2
2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
an L-amino acid + H2O + O2
a 2-oxo-acid + NH3 + H2O2
show the reaction diagram
-
L-amino-acid oxidase catalyzes the oxidative deamination of a number of L-amino acids to their respective imino acids with concomitant hydrolysis to alpha-keto acids, together with the production of ammonia and hydrogen peroxide
-
-
?
DL-3-(1-pyridyl)-alanine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
24% of the activity compared to L-alanine
-
?
DL-3-(1-pyridyl)alanine + H2O + O2
3-(1-pyridyl)pyruvate + NH3 + H2O2
show the reaction diagram
24% of the activity with L-Ala
-
-
?
DL-4-fluorophenylalanine + H2O + O2
(4-fluorophenyl)pyruvate + NH3 + H2O2
show the reaction diagram
25% of the activity with L-Ala
-
-
?
DL-4-fluorophenylalanine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
25% of the activity compared to L-alanine
-
?
DL-asparagine + H2O + O2
2-oxosuccinamic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-beta-phenylserine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
8% of the activity with L-Ala
-
-
?
DL-homophenylalanine + H2O + O2
2-oxo-4-phenylbutanoic acid + NH3 + H2O2
show the reaction diagram
50% of the activity compared to L-alanine
-
?
DL-homophenylalanine + H2O + O2
2-oxo-4-phenylbutyric acid + NH3 + H2O2
show the reaction diagram
50% of the activity with L-Ala
-
-
?
DL-leucine + H2O + O2
2-oxo-4-methylpentanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
DL-methionine + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
DL-norleucine + H2O + O2
2-oxocaproate + NH3 + H2O2
show the reaction diagram
DL-norleucine + H2O + O2
alpha-ketocaproate + NH3 + H2O2
show the reaction diagram
DL-O-methylserine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
DL-phenylseine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
8% of the activity compared to L-alanine
-
?
DL-threonine + H2O + O2
2-oxo-3-hydroxybutanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-valine + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
glycine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
glycine + H2O + O2
glyoxylate + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
-
hydroxyisovaleric acid + H2O + O2
? + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-2,3-diaminopropionic acid + H2O + O2
? + NH3 + H2O2
show the reaction diagram
L-2,4-diaminobutyric acid + H2O + O2
? + NH3 + H2O2
show the reaction diagram
L-2-4,4,dimethylvaleric acid + H2O + O2
? + NH3 + H2O2
show the reaction diagram
46% of the activity compared to L-alanine
-
?
L-2-amino-4,4-dimethylhexanoic acid + H2O + O2
4,4-dimethyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
44% of the activity with L-Ala
-
-
?
L-2-amino-4,4-dimethylvaleric acid + H2O + O2
4,4-dimethyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
46% of the activity with L-Ala
-
-
?
L-2-amino-5,5-dimethylhexanoic acid + H2O + O2
? + NH3 + H2O2
show the reaction diagram
44% of the activity compared to L-alanine
-
?
L-2-chlorophenylalanine + H2O + O2
(2-chlorophenyl)pyruvate + NH3 + H2O2
show the reaction diagram
24% of the activity with L-Ala
-
-
?
L-2-chlorophenylalanine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
24% of the activity compared to L-alanine
-
?
L-3-(1-naphthyl)alanine + H2O + O2
3-(1-naphthyl)pyruvate + NH3 + H2O2
show the reaction diagram
109% of the activity with L-Ala
-
-
?
L-3-(naphthyl)alanine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
109% of the activity compared to L-alanine
-
?
L-4-aminophenylalanine + H2O + O2
(4-aminophenyl)pyruvate + NH3 + H2O2
show the reaction diagram
16% of the activity with L-Ala
-
-
?
L-4-aminophenylalanine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
16% of the activity compared to L-alanine
-
?
L-4-chlorophenylalanine + H2O + O2
(4-chlorophenyl)pyruvate + NH3 + H2O2
show the reaction diagram
9% of the activity with L-Ala
-
-
?
L-4-chlorophenylalanine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
9% of the activity compared to L-alanine
-
?
L-4-nitrophenylalanine + H2O + O2
(4-nitrophenyl)pyruvate + NH3 + H2O2
show the reaction diagram
30% of the activity with L-Ala
-
-
?
L-4-nitrophenylalanine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
30% of the activity compared to L-alanine
-
?
L-Ala + H2O + O2
2-oxo-3-propanoate + NH3 + H2O2
show the reaction diagram
-
the substrate is not effectively oxidized
-
-
?
L-Ala + H2O + O2
2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
L-alanine + H2O + O2
2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
L-albizziin + H2O + O2
alpha-keto-beta-ureidopropionic acid + NH3 + H2O2
show the reaction diagram
-
L-alpha-amino-beta-ureidopropionic acid
-
-
?
L-alpha-aminobutyric acid + H2O + O2
alpha-ketobutyrate + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
2-oxo acid + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
2-oxocarboxylate + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
a 2-oxo carboxylate + NH3 + H2O2
show the reaction diagram
L-Arg + H2O + O2
2-oxo-5-guanidinovaleric acid + NH3 + H2O2
show the reaction diagram
L-Arg + H2O + O2
5-carbamidamido-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
-
the substrate is not effectively oxidized
-
-
?
L-arginine + H2O + O2
2-oxo-5-guanidinopentanoic acid + NH3 + H2O2
show the reaction diagram
L-arginine + H2O + O2
2-oxo-5-guanidinovaleric acid + NH3 + H2O2
show the reaction diagram
L-arginine + H2O + O2
5-carbamidamido-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
L-Asn + H2O + O2
2-oxosuccinamic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Asp + H2O + O2
? + NH3 + H2O2
show the reaction diagram
11% of the activity with L-Ala
-
-
?
L-Asp + H2O + O2
alpha-ketosuccinamic acid + NH3 + H2O2
show the reaction diagram
97% of the activity with L-Ala
-
-
?
L-Asp + H2O + O2
oxaloacetate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-asparagine + H2O + O2
alpha-ketosuccinamic acid + NH3 + H2O2
show the reaction diagram
L-aspartic acid + H2O + O2
oxaloacetate + NH3 + H2O2
show the reaction diagram
L-citrulline + H2O + O2
2-oxo-5-ureidovaleric acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-citrulline + H2O + O2
? + NH3 + H2O2
show the reaction diagram
74% of the activity compared to L-alanine
-
?
L-citrulline + H2O + O2
N5-carbamoyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
74% of the activity with L-Ala
-
-
?
L-cysteic acid + H2O + O2
? + NH3 + H2O2
show the reaction diagram
L-cysteine + H2O + O2
2-oxo-3-mercaptopropanoic acid + NH3 + H2O2
show the reaction diagram
L-cysteine + H2O + O2
2-oxo-3-thiopropanoate + NH3 + H2O2
show the reaction diagram
-
about 55% activity compared to L-methionine
-
-
?
L-cystine + H2O + O2
2-oxo-3-mercaptopropanoic acid + NH3 + H2O2
show the reaction diagram
104% of the activity compared to L-alanine
-
?
L-cystine + H2O + O2
?
show the reaction diagram
-
-
-
-
?
L-cystine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
L-Dopa + H2O + O2
? + NH3 + H2O2
show the reaction diagram
-
about 10% of the activity with L-Phe
-
-
?
L-Gln + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-Glu + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-glutamate + H2O + O2
2-oxoglutaric acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-glutamic acid + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-glutamine + H2O + O2
2-oxo-4-carbamoylbutanoic acid + NH3 + H2O2
show the reaction diagram
L-glutamine + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-glutamine + H2O + O2
2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
L-glutamine + H2O + O2
5-amino-2,5-dioxopentanoate + NH3 + H2O2
show the reaction diagram
-
about 11% activity compared to L-methionine
-
-
?
L-His + H2O + O2
3-(1H-imidazol-4-yl)-2-oxopropionic acid + NH3 + H2O2
show the reaction diagram
L-histidine + H2O + O2
2-oxo-4-imidazolepropionic acid + NH3 + H2O2
show the reaction diagram
L-histidine + H2O + O2
3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
about 19% activity compared to L-methionine
-
-
?
L-histidine + H2O + O2
3-(1H-imidazol-4-yl)-2-oxopropionic acid + NH3 + H2O2
show the reaction diagram
L-homocysteine + H2O + O2
4-thio-2-ketobutyric acid + NH3 + H2O2
show the reaction diagram
L-homocysteine thiolactone + H2O + O2
? + NH3 + H2O2
show the reaction diagram
L-homoserine + H2O + O2
2-oxo-4-hydroxybutyric acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-homoserine lactone + H2O + O2
? + NH3 + H2O2
show the reaction diagram
L-Ile + H2O + O2
3-methyl-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
L-isoleucine + H2O + O2
3-methyl-2-oxo-pentanoate + NH3 + H2O2
show the reaction diagram
-
substrate affinity in decreasing order: L-methionine, L-tryptophan, L-leucine, L-histidine, L-phenylalanine, L-arginine, L-isoleucine
-
-
?
L-isoleucine + H2O + O2
3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
show the reaction diagram
L-isoleucine + H2O + O2
3-methyl-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
L-isoleucine + H2O + O2
3-methyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
L-isoleucine + H2O + O2
alpha-keto-beta-methyl-pentanoic acid + NH3 + H2O2
show the reaction diagram
L-lactic acid + H2O + O2
pyruvate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Leu + H2O + O2
2-oxo-4-methylvaleric acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Leu + H2O + O2
4-methyl-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
-
best substrate
-
-
?
L-Leu + H2O + O2
4-methyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
L-leucine + H2O + O2
2-oxo-4-methylpentanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-leucine + H2O + O2
2-oxo-4-methylvaleric acid + NH3 + H2O2
show the reaction diagram
L-leucine + H2O + O2
4-methyl-2-oxo-pentanoic acid + NH3 + H2O2
show the reaction diagram
-
about 99% activity compared to L-methionine
-
-
?
L-leucine + H2O + O2
4-methyl-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
-
about 97% activity compared to L-methionine
-
-
?
L-leucine + H2O + O2
4-methyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
L-Lys + H2O + O2
6-amino-2-oxo-hexanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
?
L-Lys + H2O + O2
6-amino-2-oxohexanoate + NH3 + H2O2
show the reaction diagram
-
the substrate is not effectively oxidized
-
-
?
L-Lys + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
L-lysine + H2O + O2
6-amino-2-oxohexanoate + NH3 + H2O2
show the reaction diagram
L-lysine + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
L-Met + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
L-Met + H2O + O2
4-methylthio-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-methionine + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
L-methionine + H2O + O2
4-methylthio-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
-
100% activity
-
-
?
L-norleucine + H2O + O2
2-oxohexanoate + NH3 + H2O2
show the reaction diagram
-
high catalytic activity
-
-
?
L-norleucine + H2O + O2
alpha-ketocaproate + NH3 + H2O2
show the reaction diagram
L-norvaline + H2O + O2
2-oxo-valeric acid + NH3 + NADH + NH3 + H2O2
show the reaction diagram
L-Orn + H2O + O2
2-oxo-5-aminopentanoate + NH3 + H2O2
show the reaction diagram
117% of the activity with L-Ala
-
-
?
L-ornithine + H2O + O2
2-oxo-5-aminopentanoate + NH3 + H2O2
show the reaction diagram
L-ornithine + H2O + O2
?
show the reaction diagram
L-Phe + H2O + O2
2-oxo-3-phenylpropanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Phe + H2O + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
L-phenylalanine + H2O + O2
2-oxo-3-phenylpropanoate + NH3 + H2O2
show the reaction diagram
-
about 74% activity compared to L-methionine
-
-
?
L-phenylalanine + H2O + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
L-phenylalanine + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
-
inhibition of T cell proliferation through phenylalanine degradation
activity measurement by measuring H2O2 production
-
?
L-phenylglycine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
5% of the activity compared to L-alanine
-
?
L-phenylglycine + H2O + O2
phenylacetate + NH3 + H2O2
show the reaction diagram
5% of the activity with L-Ala
-
-
?
L-Pro + H2O + O2
? + NH3 + H2O2
show the reaction diagram
-
less than 10% of the activity with L-Phe
-
-
?
L-proline + H2O + O2
? + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-propargylglycine + H2O + O2
2-oxopent-4-ynoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-propargylglycine + H2O + O2
3-amino-5-methylene-5H-furan-2-one + NH3 + H2O2
show the reaction diagram
L-Ser + H2O + O2
2-oxo-3-hydroxypropionic acid + NH3 + H2O2
show the reaction diagram
72% of the activity with L-Ala
-
-
?
L-serine + H2O + O2
2-oxo-3-hydroxypropionic acid + NH3 + H2O2
show the reaction diagram
L-serine + H2O + O2
3-hydroxy-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
about 12% activity compared to L-methionine
-
-
?
L-threonine + H2O + O2
2-oxo-3-hydroxybutanoic acid + NH3 + H2O2
show the reaction diagram
L-threonine + H2O + O2
3-hydroxy-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
-
about 11% activity compared to L-methionine
-
-
?
L-Trp + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Trp + H2O + O2
indol-3-pyruvate + NH3 + H2O2
show the reaction diagram
L-Trp + H2O + O2
indole-3-pyruvate + NH3 + H2O2
show the reaction diagram
12% of the activity with L-Ala
-
-
?
L-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
L-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-tryptophan + H2O + O2
3-indole-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
L-tryptophan + H2O + O2
? + NH3 + H2O2
show the reaction diagram
L-tryptophan + H2O + O2
indole-3-pyruvate + NH3 + H2O2
show the reaction diagram
-
about 55% activity compared to L-methionine
-
-
?
L-Tyr + H2O + O2
3-(4-hydroxyphenyl)-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Tyr + H2O + O2
4-hydroxyphenylpyruvate + NH3 + H2O2
show the reaction diagram
L-Tyr + H2O + O2
p-hydroxyphenylpyruvate + NH3 + H2O2
show the reaction diagram
L-tyrosine + H2O + O2
3-(4-hydroxyphenyl)-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
about 68% activity compared to L-methionine
-
-
?
L-tyrosine + H2O + O2
4-hydroxyphenylpyruvate + NH3 + H2O2
show the reaction diagram
L-tyrosine + H2O + O2
p-hydroxyphenylpyruvate + NH3 + H2O2
show the reaction diagram
L-Val + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
L-Val + H2O + O2
3-methyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
-
the substrate is not effectively oxidized
-
-
?
L-valine + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
L-valine + H2O + O2
3-methyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
-
about 22% activity compared to L-methionine
-
-
?
lysine + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
mandelic acid + H2O + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
Nepsilon-acetyl-L-Lys + H2O + O2
6-acetylamino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
46% of the activity with L-Ala
-
-
?
Nepsilon-acetyl-L-lysine + H2O + O2
2-oxo-6-acetylaminohexanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
Nepsilon-acetyl-L-lysine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
46% of the activity compared to L-alanine
-
?
O-carbamoyl-L-serine + H2O + O2
3-O-carbamoyl-2-keto-propionic acid + NH3 + H2O2
show the reaction diagram
S-adenosyl-L-homocysteine + H2O + O2
4-thioadenosyl-2-oxobutyrate + NH3 + H2O2
show the reaction diagram
S-allyl-L-cysteine + H2O + O2
2-oxo-3-(prop-2-en-1-ylsulfanyl)propanoic acid + NH3 + H2O2
show the reaction diagram
-
94% of the activity with L-methionine
-
-
?
S-allylmercapto-L-cysteine + H2O + O2
2-oxo-3-[(2-thioxoethyl)sulfanyl]propanoic acid + NH3 + H2O2
show the reaction diagram
-
26% of the activity with L-methionine
-
-
?
S-benzothiazolyl-L-cysteine + H2O + O2
3-(1,3-benzothiazol-3(2H)-ylsulfanyl)-2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
-
161% of the activity with L-methionine
-
-
?
S-carbamoyl-L-cysteine + H2O + O2
3-thiocarbamoyl-2-keto-propionic acid + NH3 + H2O2
show the reaction diagram
S-methylmercapto-L-cysteine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
-
66% of the activity with L-methionine
-
-
?
S-penta-1,3-dienylmercapto-L-cysteine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
-
7% of the activity with L-methionine
-
-
?
S-propylmercapto-L-cysteine + H2O + O2
2-oxo-3-[(3-thioxopropyl)sulfanyl]propanoic acid + NH3 + H2O2
show the reaction diagram
-
16% of the activity with L-methionine
-
-
?
thyroxine + H2O + O2
3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenylpyruvate] + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
triiodothyronine + H2O + O2
3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-2-oxopropionic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
additional information
?
-