Application | Comment | Organism |
---|---|---|
medicine | induces apoptosis in Hela cervical cancer cells in a concentration- and time-dependent manner. Caspase activation and PARP cleavage are involved in ACTX-8-induced apoptosis. ACTX-8 activates a mitochondrial pathway of apoptosis, which is regulated by Bcl-2 family members. Reactive oxygen species generated by ACTX-8 are involved in apoptosis. Translocation of Bax and Bad from the cytosol into mitochondria in ACTX-8-treated cells | Deinagkistrodon acutus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Deinagkistrodon acutus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Deinagkistrodon acutus | - |
Synonyms | Comment | Organism |
---|---|---|
ACTX-8 | - |
Deinagkistrodon acutus |