Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-propargylglycine | irreversible inhibition in a dose- and time-dependent manner | Crotalus adamanteus | |
L-propargylglycine | irreversible inhibition in a dose- and time-dependent manner | Crotalus atrox |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03601 | - |
L-phenylalanine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus atrox | |
0.03782 | - |
L-phenylalanine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus adamanteus | |
7.95 | - |
L-propargylglycine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus adamanteus | |
11.78 | - |
L-propargylglycine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus atrox |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Crotalus adamanteus | - |
- |
- |
Crotalus atrox | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Crotalus adamanteus | - |
venom | - |
Crotalus atrox | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-phenylalanine + H2O + O2 | - |
Crotalus adamanteus | phenylpyruvate + NH3 + H2O2 | - |
? | |
L-phenylalanine + H2O + O2 | - |
Crotalus atrox | phenylpyruvate + NH3 + H2O2 | - |
? | |
L-propargylglycine + O2 | the substrate L-propargylglycine competes with the substrate L-Phe during inactivation of the enzyme | Crotalus adamanteus | 3-amino-5-methylene-5H-furan-2-one + H2O2 | - |
? | |
L-propargylglycine + O2 | the substrate L-propargylglycine competes with the substrate L-Phe during inactivation of the enzyme | Crotalus atrox | 3-amino-5-methylene-5H-furan-2-one + H2O2 | - |
? | |
additional information | glycine is not oxidized by the enzyme | Crotalus adamanteus | ? | - |
? | |
additional information | glycine is not oxidized by the enzyme | Crotalus atrox | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-amino acid oxidase | - |
Crotalus adamanteus |
L-amino acid oxidase | - |
Crotalus atrox |
LAAO | - |
Crotalus adamanteus |
LAAO | - |
Crotalus atrox |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
6.27 | - |
L-phenylalanine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus adamanteus | |
6.78 | - |
L-phenylalanine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus atrox | |
7.75 | - |
L-propargylglycine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus atrox | |
9.62 | - |
L-propargylglycine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus adamanteus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Crotalus adamanteus | |
FAD | - |
Crotalus atrox |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
7.49 | - |
L-propargylglycine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus adamanteus | |
9.69 | - |
L-propargylglycine | in 20 mM Na-phosphate, pH 7.5, at 28°C | Crotalus atrox |