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Literature summary for 1.4.3.2 extracted from

  • Mason, J.M.; Naidu, M.D.; Barcia, M.; Porti, D.; Chavan, S.S.; Chu, C.C.
    IL-4-induced gene-1 is a leukocyte L-amino acid oxidase with an unusual acidic pH preference and lysosomal localization (2004), J. Immunol., 173, 4561-4567.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.5
-
L-Phe
-
Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
Mus musculus 5764
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein N-linked glycosylation Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Dopa + H2O + O2 about 10% of the activity with L-Phe Mus musculus ? + NH3 + H2O2
-
?
L-Phe + H2O + O2 best substrate Mus musculus phenylpyruvate + NH3 + H2O2
-
?
L-Pro + H2O + O2 less than 10% of the activity with L-Phe Mus musculus ? + NH3 + H2O2
-
?
L-tryptophan + H2O + O2 about 30% of the activity with L-Phe Mus musculus indole-3-pyruvate + NH3 + H2O2
-
?
L-Tyr + H2O + O2 about 40% of the activity with L-Phe Mus musculus p-hydroxyphenylpyruvate + NH3 + H2O2
-
?
additional information the enzyme has a preference for aromatic amin acids, less than 5% of the activity with L-Phe: Gln, Gly, Asn, His, Leu, Glu, Lys Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
IL4I1
-
Mus musculus
Il4i1 protein
-
Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4
-
-
Mus musculus