4.4.1.20: leukotriene-C4 synthase

This is an abbreviated version!
For detailed information about leukotriene-C4 synthase, go to the full flat file.

Word Map on EC 4.4.1.20

4.4.1.20

asthma

lta4

cysteinyl

5-lipoxygenase

arachidonic

eosinophil

asthmatic

flap

bronchial

eicosanoids

aspirin

cysteinyl-leukotrienes

cys-lts

cysltr1

aspirin-induced

bronchoconstriction

5-lipoxygenase-activating

aspirin-intolerant

alox5ap

montelukast

1-chloro-2,4-dinitrobenzene

mapeg

aspirin-exacerbated

rbl-1

medicine

bronchoconstrictors

a23187-stimulated

molecular biology

drug development

analysis

Reaction

Synonyms

(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening), EC 2.5.1.37, leukotriene A4:glutathione S-leukotrienyltransferase, leukotriene C4 synthase, leukotriene C4 synthetase, LT C4 synthase, LTC4 synthase, LTC4 synthetase, LTC4S, LTCS, synthase, leukotriene C4

ECTree

4 Lyases

4.4 Carbon-sulfur lyases

4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)

4.4.1.20 leukotriene-C4 synthase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
12	Activating Compound
13	AA Sequence
17	Application
1	CAS Registry Number
25	Cloned(Commentary)
12	Crystallization (Commentary)
300	Disease/ Diagnostics
7	Expression
12	General Information
2	General Stability
20	IC50 Value
51	Inhibitors
28	kcat/KM [mM/s]
4	Ki Value [mM]
56	KM Value [mM]
53	Localization
6	Metals/Ions
15	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
255	Organism
7	Pathway
39	PDB ID
5	pH Optimum
1	pH Range
2	pI Value
2	Posttranslational Modification
65	Protein Variants
20	Purification (Commentary)
3	Reaction
12	Reaction Type
93	Reference
142	Source Tissue
19	Specific Activity [micromol/min/mg]
2	Storage Stability
106	Substrates and Products (Substrate)
21	Subunits
99	Synonyms
1	Systematic Name
4	Temperature Stability [°C]
36	Turnover Number [1/s]

Organism

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Organism on EC 4.4.1.20 - leukotriene-C4 synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Organism Search

Apostichopus japonicus

bifunctional enzyme, acts as glutathione transferase and LTC4 synthase

UniProt

644486, 644496, 644499, 644502, 644506

no activity in Sus scrofa

no activity in platelets

644501

Oryctolagus cuniculus

Rattus norvegicus Sprague-Dawley

Sprague-Dawley

678098