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4.4.1.20: leukotriene-C4 synthase

This is an abbreviated version!
For detailed information about leukotriene-C4 synthase, go to the full flat file.

Word Map on EC 4.4.1.20

Reaction

leukotriene C4
=
leukotriene A4
+
glutathione

Synonyms

(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening), EC 2.5.1.37, leukotriene A4:glutathione S-leukotrienyltransferase, leukotriene C4 synthase, leukotriene C4 synthetase, LT C4 synthase, LTC4 synthase, LTC4 synthetase, LTC4S, LTCS, synthase, leukotriene C4

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.20 leukotriene-C4 synthase

Sequence

Sequence on EC 4.4.1.20 - leukotriene-C4 synthase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
MGST2_MOUSE
147
2
16786
Swiss-Prot
Secretory Pathway (Reliability: 2)
MGST3_HUMAN
152
4
16516
Swiss-Prot
Secretory Pathway (Reliability: 3)
MGST2_BOVIN
146
2
16483
Swiss-Prot
Secretory Pathway (Reliability: 2)
MGST2_HUMAN
147
2
16621
Swiss-Prot
Secretory Pathway (Reliability: 2)
GSTM4_HUMAN
218
0
25561
Swiss-Prot
other Location (Reliability: 5)
GSTM4_MOUSE
218
0
25519
Swiss-Prot
other Location (Reliability: 5)
GSTM4_RAT
218
0
25553
Swiss-Prot
other Location (Reliability: 5)
LTC4S_BOVIN
150
3
16701
Swiss-Prot
Secretory Pathway (Reliability: 1)
LTC4S_CAVPO
150
3
16748
Swiss-Prot
Secretory Pathway (Reliability: 2)
LTC4S_HUMAN
150
3
16567
Swiss-Prot
Secretory Pathway (Reliability: 1)
LTC4S_MOUSE
150
3
16814
Swiss-Prot
Secretory Pathway (Reliability: 1)
LTC4S_RAT
150
3
16850
Swiss-Prot
Secretory Pathway (Reliability: 1)
A0A219VGM9_STIJA
161
0
18348
TrEMBL
-